| Definition | Prochlorococcus marinus str. MIT 9313 chromosome, complete genome. |
|---|---|
| Accession | NC_005071 |
| Length | 2,410,873 |
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The map label for this gene is murF [H]
Identifier: 33862674
GI number: 33862674
Start: 450925
End: 452322
Strand: Reverse
Name: murF [H]
Synonym: PMT0401
Alternate gene names: 33862674
Gene position: 452322-450925 (Counterclockwise)
Preceding gene: 33862675
Following gene: 33862669
Centisome position: 18.76
GC content: 54.72
Gene sequence:
>1398_bases ATGAGACTGCGTCTGGGGCAGCTGGTCGAGTTTTGGGGTGCTCCGATGCATGTTCACGCGTCTGACCTAGATCTTGACCA AGCTGTTGGTCCGATCTGCACAGACAGTCGTCAGTTGAGCGAAGGCAGCTTCTTTGTGCCGTTGGTGGGGGAGCATTTCA ATGGCCATGCCTTTCTTGCTCAAGCTCTGAAGCTTGAGGTCCAGGCGGCTGTGGTGGCTCGCAAAGATCATCATCCAGTA CCCGAGGGTCTCCCCCATTGGATTGTGGAAGACACTCTCGAGGCTTATCAGCAACTGGGGTTGCTGCATCGCCGTCAGTT GAATGTACCGGTGGTTGCCGTCACAGGTTCAGCAGGAAAAACCACGACTCGGGAGTTGATCCGCTCTGCACTCACACCCC TTGGTGAGGTCTTGGCAAGTGCAGGCAACAACAACAACGACGTGGGTGTTCCGCTCACCTTGTTGCAGGCTCATTCAGAT CATGGCGCAGTTGTGGTAGAGATGGGGATGCGTGGAATTGGGGAAATAGAACGTCTCTCCTGTTGCACCCAACCAGACGT CGCTGTGATCACCAATATCGGCAATGCACACGTCGGTCGTTTAGGTAGTCGTGCGGCGATTGCTTCCGCCAAGTGTGAGA TCACCACTTGCCTGAAACCCAGAGGCGTGATCGTTATCCCAGCAGGGGATTTGCTCCTGGAAGATGCTCTTGAACGGATC TGGCGGGGGCGGGTGATCCGCGTGGCAGTTCAAGACAATCAACAATTAGAGCCACCAGAGATTGCAGATCTGCATCGAAG ACCTCTACCCAAGGCCGATCTCGTTGGCTGCGTTGACCTGGCCAAGGGTGAACTATTGCTAGAAGGAAATGCCTACACCC TGCCTTTAGAAGGGATGCATAACGCTTGCAATTTGATGCTGGCACTCGCAGTTGCCCGTGAATTAGATGTCTGCAAGGAA TCGCTATCCAATCTAAAGGTAGACGTTCCTGGTGGCCGTAGTCGACGGCTAAAAGTTGGCAACTTCACTGTTCTAGACGA GACCTACAACGCTTCGCCCGAAGCCGTGCAAGCAGCATTGGAACTATTAGCAATTCAACCGGGGCGTCACTTTGCAGTCC TCGGAACCATGCTGGAGCTAGGAGACCAGAGCGTGGCTTTGCATCGCCAAGTTGCTGAACGGGCGGTACAAGTTGGTTTA GATGGACTCGTCGTCGTTGCTGCAGGCGCTGAGGCTGAGGCCATGGCAACAGCAGCAGGGTCCTTGCCGCATTTGGCCGT CGTTGCCAACCCAGAGCAGGCTGCTCAGCCATTGCAGGCTTGGCTTGAGGCCGGCGATGTGGTTCTGCTTAAGGCTAGTC GTGGTGTCGCTCTAGAGAAATTGATCCCATTGCTCTAA
Upstream 100 bases:
>100_bases GTTATGACGAACTTCAACTTCAAAGCGAGGATGATCAACTGCTTGCCAGGACAGCAAGAGTGGGTGTGGGCATGATCATT TTCGATCAGGATTTGGCTTA
Downstream 100 bases:
>100_bases GAGGGCTAAGCCTTAATCCTCTCGTTTCACTGCCAACCATTTTTAATCAGTTGTTTGGAGCGGCCAAGGGCGAGAGCACC ATTGGGAACATCTTTAGTGA
Product: cytoplasmic peptidoglycan synthetase
Products: NA
Alternate protein names: D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetase [H]
Number of amino acids: Translated: 465; Mature: 465
Protein sequence:
>465_residues MRLRLGQLVEFWGAPMHVHASDLDLDQAVGPICTDSRQLSEGSFFVPLVGEHFNGHAFLAQALKLEVQAAVVARKDHHPV PEGLPHWIVEDTLEAYQQLGLLHRRQLNVPVVAVTGSAGKTTTRELIRSALTPLGEVLASAGNNNNDVGVPLTLLQAHSD HGAVVVEMGMRGIGEIERLSCCTQPDVAVITNIGNAHVGRLGSRAAIASAKCEITTCLKPRGVIVIPAGDLLLEDALERI WRGRVIRVAVQDNQQLEPPEIADLHRRPLPKADLVGCVDLAKGELLLEGNAYTLPLEGMHNACNLMLALAVARELDVCKE SLSNLKVDVPGGRSRRLKVGNFTVLDETYNASPEAVQAALELLAIQPGRHFAVLGTMLELGDQSVALHRQVAERAVQVGL DGLVVVAAGAEAEAMATAAGSLPHLAVVANPEQAAQPLQAWLEAGDVVLLKASRGVALEKLIPLL
Sequences:
>Translated_465_residues MRLRLGQLVEFWGAPMHVHASDLDLDQAVGPICTDSRQLSEGSFFVPLVGEHFNGHAFLAQALKLEVQAAVVARKDHHPV PEGLPHWIVEDTLEAYQQLGLLHRRQLNVPVVAVTGSAGKTTTRELIRSALTPLGEVLASAGNNNNDVGVPLTLLQAHSD HGAVVVEMGMRGIGEIERLSCCTQPDVAVITNIGNAHVGRLGSRAAIASAKCEITTCLKPRGVIVIPAGDLLLEDALERI WRGRVIRVAVQDNQQLEPPEIADLHRRPLPKADLVGCVDLAKGELLLEGNAYTLPLEGMHNACNLMLALAVARELDVCKE SLSNLKVDVPGGRSRRLKVGNFTVLDETYNASPEAVQAALELLAIQPGRHFAVLGTMLELGDQSVALHRQVAERAVQVGL DGLVVVAAGAEAEAMATAAGSLPHLAVVANPEQAAQPLQAWLEAGDVVLLKASRGVALEKLIPLL >Mature_465_residues MRLRLGQLVEFWGAPMHVHASDLDLDQAVGPICTDSRQLSEGSFFVPLVGEHFNGHAFLAQALKLEVQAAVVARKDHHPV PEGLPHWIVEDTLEAYQQLGLLHRRQLNVPVVAVTGSAGKTTTRELIRSALTPLGEVLASAGNNNNDVGVPLTLLQAHSD HGAVVVEMGMRGIGEIERLSCCTQPDVAVITNIGNAHVGRLGSRAAIASAKCEITTCLKPRGVIVIPAGDLLLEDALERI WRGRVIRVAVQDNQQLEPPEIADLHRRPLPKADLVGCVDLAKGELLLEGNAYTLPLEGMHNACNLMLALAVARELDVCKE SLSNLKVDVPGGRSRRLKVGNFTVLDETYNASPEAVQAALELLAIQPGRHFAVLGTMLELGDQSVALHRQVAERAVQVGL DGLVVVAAGAEAEAMATAAGSLPHLAVVANPEQAAQPLQAWLEAGDVVLLKASRGVALEKLIPLL
Specific function: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein [H]
COG id: COG0770
COG function: function code M; UDP-N-acetylmuramyl pentapeptide synthase
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786274, Length=470, Percent_Identity=32.5531914893617, Blast_Score=179, Evalue=4e-46,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005863 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.10 [H]
Molecular weight: Translated: 49557; Mature: 49557
Theoretical pI: Translated: 5.83; Mature: 5.83
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLRLGQLVEFWGAPMHVHASDLDLDQAVGPICTDSRQLSEGSFFVPLVGEHFNGHAFLA CCCCHHHHHHHHCCCEEEECCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHH QALKLEVQAAVVARKDHHPVPEGLPHWIVEDTLEAYQQLGLLHRRQLNVPVVAVTGSAGK HHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC TTTRELIRSALTPLGEVLASAGNNNNDVGVPLTLLQAHSDHGAVVVEMGMRGIGEIERLS HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHH CCTQPDVAVITNIGNAHVGRLGSRAAIASAKCEITTCLKPRGVIVIPAGDLLLEDALERI CCCCCCEEEEEECCCHHHHCCCCCHHHHCCCEEEEEEECCCCEEEECCCHHHHHHHHHHH WRGRVIRVAVQDNQQLEPPEIADLHRRPLPKADLVGCVDLAKGELLLEGNAYTLPLEGMH HCCCEEEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHEECCCCEEEECCEEEEEHHCCH NACNLMLALAVARELDVCKESLSNLKVDVPGGRSRRLKVGNFTVLDETYNASPEAVQAAL HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCEEEECCEEEEECCCCCCHHHHHHHH ELLAIQPGRHFAVLGTMLELGDQSVALHRQVAERAVQVGLDGLVVVAAGAEAEAMATAAG HHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCC SLPHLAVVANPEQAAQPLQAWLEAGDVVLLKASRGVALEKLIPLL CCCEEEEEECHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCC >Mature Secondary Structure MRLRLGQLVEFWGAPMHVHASDLDLDQAVGPICTDSRQLSEGSFFVPLVGEHFNGHAFLA CCCCHHHHHHHHCCCEEEECCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHH QALKLEVQAAVVARKDHHPVPEGLPHWIVEDTLEAYQQLGLLHRRQLNVPVVAVTGSAGK HHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC TTTRELIRSALTPLGEVLASAGNNNNDVGVPLTLLQAHSDHGAVVVEMGMRGIGEIERLS HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHH CCTQPDVAVITNIGNAHVGRLGSRAAIASAKCEITTCLKPRGVIVIPAGDLLLEDALERI CCCCCCEEEEEECCCHHHHCCCCCHHHHCCCEEEEEEECCCCEEEECCCHHHHHHHHHHH WRGRVIRVAVQDNQQLEPPEIADLHRRPLPKADLVGCVDLAKGELLLEGNAYTLPLEGMH HCCCEEEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHEECCCCEEEECCEEEEEHHCCH NACNLMLALAVARELDVCKESLSNLKVDVPGGRSRRLKVGNFTVLDETYNASPEAVQAAL HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCEEEECCEEEEECCCCCCHHHHHHHH ELLAIQPGRHFAVLGTMLELGDQSVALHRQVAERAVQVGLDGLVVVAAGAEAEAMATAAG HHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCC SLPHLAVVANPEQAAQPLQAWLEAGDVVLLKASRGVALEKLIPLL CCCEEEEEECHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7894708; 8905231 [H]