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The map label for this gene is aroA [H]

Identifier: 33862671

GI number: 33862671

Start: 446843

End: 448168

Strand: Direct

Name: aroA [H]

Synonym: PMT0398

Alternate gene names: 33862671

Gene position: 446843-448168 (Clockwise)

Preceding gene: 33862670

Following gene: 33862672

Centisome position: 18.53

GC content: 56.03

Gene sequence:

>1326_bases
TTGAGCGTTACAAACACTGCCTCATCGTCATGTGAGCTTCGAGCAGGTGGTGGGCTTTCTGGAACGGTGCGAGTCCCTGG
AGACAAATCGATTTCCCATCGAGCGCTGTTATTTGGAGCTATCGCAGAAGGGGTCACAACCATCGAGGGCCTTTTACCTG
CTGAAGATCCCATGAGTACCGCCGCCTGTCTTAGAGCGATGGGAGCCACGATCGGCCCGATTCATGTCGGGCAAATAGTT
CGCGTTGAAGGCGTTGGTCTCGATGGACTCCAAGAACCGCAAGATGTACTCGACTGCGGTAACTCCGGCACAACAATTCG
GCTGATGCTAGGGCTGTTGGCGGCACGCAAGGGCCGCCATTTCGTGCTTAGCGGTGATGCCTCTTTGCGCCGTAGACCGA
TGAATCGGGTTGGCCAGCCATTAACAATGATGGGAGCCAAAATTAAAGGACGATCCAACGGCGACTTCGCACCACTTGCC
GTGAGCGGTCAGAAACTTCGTGGTGGTGTCATCGGTACACCTGTAGCAAGTGCCCAGGTGAAGTCAGCCCTGCTGCTGGC
AGCCCTTACAGCCGATGGGGCAACGACTGTGATCGAACCAGCCCATTCGAGAGACCACAGCGAACGCATGTTGCGGGCAT
TCGGTGCTGATCTCGAGGTGGGAGGAGAGATGGGTCGCCATATCAGAGTGAGCCCAGGACAAAAGCTTTATGGGCAAAAT
ATTGTCGTGCCAGGTGATATCAGTTCCGCTGCTTTTTGGCTTGTCGCAGGAGCGCTTGTTCCTGGAGCTGAGCTCGTGGT
GGAAAACGTTGGTTTAAACCCCACCCGTACCGGCATTCTGGAAGTGTTGCAGCAAATGGAAGCTCGCATTGAGGTGCTCA
ACCGCCATGAAGTCGCCGGTGAACCAGTTGGAGACCTACGGGTGAGGCAAGGATCGTTAAAGCCCTTCAGCATCAATGGG
GACATCATTCCTCGCCTGGTCGATGAGGTGCCGATCCTGGCGGTGGCTGCTTGTTTCTGTGATGGTGAAAGCAAAATTAC
TGACGCCAGTGAACTGCGCGTCAAGGAAACCGATCGGCTCGCTGTGATGACCAGGCAGCTCACGGCTATGGGAGCAGATA
TCGACGAACATGCCGATGGGCTCACCATCCGAGGGGGACGAACACTGCGAGGCACAGACCTCGATAGTGAAACGGATCAT
CGAGTCGCCATGAGTCTGGCGGTGGCTGCGTTGCTGGCGGAGGGCAATTCTCGCTTGACTGGTAGCGAAGCTGCGGCTGT
GTCCTACCCCAACTTCTGGGATGACCTTGAGCGGCTGCATCGCTAA

Upstream 100 bases:

>100_bases
TTGAGATGGTCCAAAAGAAACAAATTACACAGCACAAAAACAAATTGGAAATAAGGTCAAACGCTTGACCATAAGATCGA
TCTGATCCGGGCCACACCCA

Downstream 100 bases:

>100_bases
TGCCGGCCACTCTCGCCCTTTGGGGGCACTGAATGTTTTCCCAACGGCGGATGGTAGCTTTAGCCTGCATAGTGAGTACT
TCGACGAAGCGTTCCACAAC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSVTNTASSSCELRAGGGLSGTVRVPGDKSISHRALLFGAIAEGVTTIEGLLPAEDPMSTAACLRAMGATIGPIHVGQIV
RVEGVGLDGLQEPQDVLDCGNSGTTIRLMLGLLAARKGRHFVLSGDASLRRRPMNRVGQPLTMMGAKIKGRSNGDFAPLA
VSGQKLRGGVIGTPVASAQVKSALLLAALTADGATTVIEPAHSRDHSERMLRAFGADLEVGGEMGRHIRVSPGQKLYGQN
IVVPGDISSAAFWLVAGALVPGAELVVENVGLNPTRTGILEVLQQMEARIEVLNRHEVAGEPVGDLRVRQGSLKPFSING
DIIPRLVDEVPILAVAACFCDGESKITDASELRVKETDRLAVMTRQLTAMGADIDEHADGLTIRGGRTLRGTDLDSETDH
RVAMSLAVAALLAEGNSRLTGSEAAAVSYPNFWDDLERLHR

Sequences:

>Translated_441_residues
MSVTNTASSSCELRAGGGLSGTVRVPGDKSISHRALLFGAIAEGVTTIEGLLPAEDPMSTAACLRAMGATIGPIHVGQIV
RVEGVGLDGLQEPQDVLDCGNSGTTIRLMLGLLAARKGRHFVLSGDASLRRRPMNRVGQPLTMMGAKIKGRSNGDFAPLA
VSGQKLRGGVIGTPVASAQVKSALLLAALTADGATTVIEPAHSRDHSERMLRAFGADLEVGGEMGRHIRVSPGQKLYGQN
IVVPGDISSAAFWLVAGALVPGAELVVENVGLNPTRTGILEVLQQMEARIEVLNRHEVAGEPVGDLRVRQGSLKPFSING
DIIPRLVDEVPILAVAACFCDGESKITDASELRVKETDRLAVMTRQLTAMGADIDEHADGLTIRGGRTLRGTDLDSETDH
RVAMSLAVAALLAEGNSRLTGSEAAAVSYPNFWDDLERLHR
>Mature_440_residues
SVTNTASSSCELRAGGGLSGTVRVPGDKSISHRALLFGAIAEGVTTIEGLLPAEDPMSTAACLRAMGATIGPIHVGQIVR
VEGVGLDGLQEPQDVLDCGNSGTTIRLMLGLLAARKGRHFVLSGDASLRRRPMNRVGQPLTMMGAKIKGRSNGDFAPLAV
SGQKLRGGVIGTPVASAQVKSALLLAALTADGATTVIEPAHSRDHSERMLRAFGADLEVGGEMGRHIRVSPGQKLYGQNI
VVPGDISSAAFWLVAGALVPGAELVVENVGLNPTRTGILEVLQQMEARIEVLNRHEVAGEPVGDLRVRQGSLKPFSINGD
IIPRLVDEVPILAVAACFCDGESKITDASELRVKETDRLAVMTRQLTAMGADIDEHADGLTIRGGRTLRGTDLDSETDHR
VAMSLAVAALLAEGNSRLTGSEAAAVSYPNFWDDLERLHR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=433, Percent_Identity=27.2517321016166, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320332, Length=453, Percent_Identity=26.9315673289183, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46355; Mature: 46224

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTNTASSSCELRAGGGLSGTVRVPGDKSISHRALLFGAIAEGVTTIEGLLPAEDPMST
CCCCCCCCCCCEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
AACLRAMGATIGPIHVGQIVRVEGVGLDGLQEPQDVLDCGNSGTTIRLMLGLLAARKGRH
HHHHHHHCCCCCCEECCCEEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCE
FVLSGDASLRRRPMNRVGQPLTMMGAKIKGRSNGDFAPLAVSGQKLRGGVIGTPVASAQV
EEEECCHHHHHCCHHHHCCCHHHHCCEEECCCCCCCCEEEECCCHHCCCCCCCCCHHHHH
KSALLLAALTADGATTVIEPAHSRDHSERMLRAFGADLEVGGEMGRHIRVSPGQKLYGQN
HHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCEECCCCCCEEEECCCCHHCCCC
IVVPGDISSAAFWLVAGALVPGAELVVENVGLNPTRTGILEVLQQMEARIEVLNRHEVAG
EEECCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
EPVGDLRVRQGSLKPFSINGDIIPRLVDEVPILAVAACFCDGESKITDASELRVKETDRL
CCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCEECCCHHH
AVMTRQLTAMGADIDEHADGLTIRGGRTLRGTDLDSETDHRVAMSLAVAALLAEGNSRLT
HHHHHHHHHHCCCHHHCCCCEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
GSEAAAVSYPNFWDDLERLHR
CCCCCEECCCCHHHHHHHHCC
>Mature Secondary Structure 
SVTNTASSSCELRAGGGLSGTVRVPGDKSISHRALLFGAIAEGVTTIEGLLPAEDPMST
CCCCCCCCCCEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
AACLRAMGATIGPIHVGQIVRVEGVGLDGLQEPQDVLDCGNSGTTIRLMLGLLAARKGRH
HHHHHHHCCCCCCEECCCEEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCE
FVLSGDASLRRRPMNRVGQPLTMMGAKIKGRSNGDFAPLAVSGQKLRGGVIGTPVASAQV
EEEECCHHHHHCCHHHHCCCHHHHCCEEECCCCCCCCEEEECCCHHCCCCCCCCCHHHHH
KSALLLAALTADGATTVIEPAHSRDHSERMLRAFGADLEVGGEMGRHIRVSPGQKLYGQN
HHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCEECCCCCCEEEECCCCHHCCCC
IVVPGDISSAAFWLVAGALVPGAELVVENVGLNPTRTGILEVLQQMEARIEVLNRHEVAG
EEECCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
EPVGDLRVRQGSLKPFSINGDIIPRLVDEVPILAVAACFCDGESKITDASELRVKETDRL
CCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCEECCCHHH
AVMTRQLTAMGADIDEHADGLTIRGGRTLRGTDLDSETDHRVAMSLAVAALLAEGNSRLT
HHHHHHHHHHCCCHHHCCCCEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
GSEAAAVSYPNFWDDLERLHR
CCCCCEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA