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The map label for this gene is 33862573

Identifier: 33862573

GI number: 33862573

Start: 341494

End: 343143

Strand: Direct

Name: 33862573

Synonym: PMT0300

Alternate gene names: NA

Gene position: 341494-343143 (Clockwise)

Preceding gene: 33862569

Following gene: 33862574

Centisome position: 14.16

GC content: 39.15

Gene sequence:

>1650_bases
ATGCATGAACGAAACACCGCTGAGGAATATATAAAACGTGCTAAGGAAAAGTTCCTATTGAAAAATTATCGAGGTGCGAT
CTCTGATTGCAGCAAGGCAATAGAAATTGATCCAAAGGACTCGAGTGCCTACCACATTCGTGGTCTTGCGAGGATTATTA
GTGATGAAAAGGAATTAGCGCGTAATGATTTGTACAAGGCATCCGAGTTGGGCGACAAACATGCTATGGAGATGCTCAAG
AAGTGTTTTTATCCAAATGTACAGAATTTAATTGATTTAGAAACAAAGAAAATTGAGAAGGATGCTTCTAATTTTGAACA
TTACATAAGACGTGCTCTCCTTAAAGAAAAGTTTGACCCGAATGGAGCAATAGCGGATTATTCAAAAATATTAGAAATTG
ATTCTGAGCGTGTCGATGTTTACTTCTATCTTGCTTTAGTCAAGAATAAAGCAGGATATCCCAAACAAGCAATTGAAGAT
TGCAGAAGAGCATTAGATATCGAAGCAGGAAATCTCCTTCTCAAGGAGTATTTTGAACTTCGTAACTTTGTAAACTATCT
ATTAGATGGGAAATCTGAACCCTATCAAGACGCAGGCGACTTGATAGGGGTAATATTGGTGCGTGAACCTAAAATTACAC
CTAGTGATTCATTAGAGTATAATTTGAGAGGTATCAGAAAAGCAGATTTAAAGAACTTCCCAGGCGCAATTGATGATTTC
AGCAAGGCAATAGAACTAGAACCTAGAGACTGTCATTTGTATGTAAATAGAGGGATTTATAGGGATATGTCAGGGGACCC
TGAATCCGCAATTAGTGATTATTGCAAGGCAATAGAAATTAATCCGGATTTTGCAGATGCATACTATGAACGTGGTGTTA
CTTTAAGGGACTCAGGGCATCAGGAAAGAGCAATTTGTGATTTTTTGAAGGCAGTTGATTTAAATCCAAAATATAGTAAT
GCTTATCTCAATATAGGAAGCATAAAGTTTCATAGTTCTGATGTAAAAGGTGCCTGTGCTTACTGGAAGAAAGCATCGGA
ATTGGAAAATAAAACTGCTGACCTACTTTTAGATCAGGAATGTGCCTCACAGGGTGTACTTGCCAGTCTGAGTTATTATT
TAAACCTTGGAAGTGATAGATGTGAATCTGGCGATTTTGAAGGTGAAATTAATGCTTACGACAAAGCGCTTGAACTGAGT
CCTAATGATGCAGTTATCTATAACAACCGCGGTAATGCTAAGCGTAAGTTGGAAGACTATCAGAGTGCTATTGAGGATTA
CAATAAATCAATAGAGATCAACCCTAGTTCTGCTGCCCCTTACTTCAATCGTGGCGATATAAAGTATGTGTTAGATGACC
ATAAAGGCGCGATTGATGATTATAATCTGGCGCTAGAGGTTGATCCTGATGATCCGTTTCTCTATGCTAAACGTGGCGAC
CTAAGGGTTGCATTACATGACTATCAAGGAGCAATTGCTGATTACACAAAGGCGATAGAGATTAATCCCCAACTTGCCAT
TGCTTACTACAACCGTGGAGAGGCAAAAAAAGAAATAGGAGACCTCAAAGGTGCCTGTGAGGATTGGAAGAAAGCGGCAG
AACTAGGATACGAAGATGCTGCCAAATTGGTGGAGGAGCACTGTCAGTGA

Upstream 100 bases:

>100_bases
GTTGGCGATCATTGCTGAGAGGAACGCCTCCAAGACCCCCTAGGAGGGCAAGAAGTCTCTCCCTGCCTAGTGTGAGGTCA
TAGGAAGATGCTTTCTGCTG

Downstream 100 bases:

>100_bases
AAAATCCTCTAATCAAATTGCCTAAGAAAATACTTAGACATTATTTTCTAATGTGGGAAAGATGTCTTGATATTGATGGA
CTCTGTTCGCGGGAGGAATA

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MHERNTAEEYIKRAKEKFLLKNYRGAISDCSKAIEIDPKDSSAYHIRGLARIISDEKELARNDLYKASELGDKHAMEMLK
KCFYPNVQNLIDLETKKIEKDASNFEHYIRRALLKEKFDPNGAIADYSKILEIDSERVDVYFYLALVKNKAGYPKQAIED
CRRALDIEAGNLLLKEYFELRNFVNYLLDGKSEPYQDAGDLIGVILVREPKITPSDSLEYNLRGIRKADLKNFPGAIDDF
SKAIELEPRDCHLYVNRGIYRDMSGDPESAISDYCKAIEINPDFADAYYERGVTLRDSGHQERAICDFLKAVDLNPKYSN
AYLNIGSIKFHSSDVKGACAYWKKASELENKTADLLLDQECASQGVLASLSYYLNLGSDRCESGDFEGEINAYDKALELS
PNDAVIYNNRGNAKRKLEDYQSAIEDYNKSIEINPSSAAPYFNRGDIKYVLDDHKGAIDDYNLALEVDPDDPFLYAKRGD
LRVALHDYQGAIADYTKAIEINPQLAIAYYNRGEAKKEIGDLKGACEDWKKAAELGYEDAAKLVEEHCQ

Sequences:

>Translated_549_residues
MHERNTAEEYIKRAKEKFLLKNYRGAISDCSKAIEIDPKDSSAYHIRGLARIISDEKELARNDLYKASELGDKHAMEMLK
KCFYPNVQNLIDLETKKIEKDASNFEHYIRRALLKEKFDPNGAIADYSKILEIDSERVDVYFYLALVKNKAGYPKQAIED
CRRALDIEAGNLLLKEYFELRNFVNYLLDGKSEPYQDAGDLIGVILVREPKITPSDSLEYNLRGIRKADLKNFPGAIDDF
SKAIELEPRDCHLYVNRGIYRDMSGDPESAISDYCKAIEINPDFADAYYERGVTLRDSGHQERAICDFLKAVDLNPKYSN
AYLNIGSIKFHSSDVKGACAYWKKASELENKTADLLLDQECASQGVLASLSYYLNLGSDRCESGDFEGEINAYDKALELS
PNDAVIYNNRGNAKRKLEDYQSAIEDYNKSIEINPSSAAPYFNRGDIKYVLDDHKGAIDDYNLALEVDPDDPFLYAKRGD
LRVALHDYQGAIADYTKAIEINPQLAIAYYNRGEAKKEIGDLKGACEDWKKAAELGYEDAAKLVEEHCQ
>Mature_549_residues
MHERNTAEEYIKRAKEKFLLKNYRGAISDCSKAIEIDPKDSSAYHIRGLARIISDEKELARNDLYKASELGDKHAMEMLK
KCFYPNVQNLIDLETKKIEKDASNFEHYIRRALLKEKFDPNGAIADYSKILEIDSERVDVYFYLALVKNKAGYPKQAIED
CRRALDIEAGNLLLKEYFELRNFVNYLLDGKSEPYQDAGDLIGVILVREPKITPSDSLEYNLRGIRKADLKNFPGAIDDF
SKAIELEPRDCHLYVNRGIYRDMSGDPESAISDYCKAIEINPDFADAYYERGVTLRDSGHQERAICDFLKAVDLNPKYSN
AYLNIGSIKFHSSDVKGACAYWKKASELENKTADLLLDQECASQGVLASLSYYLNLGSDRCESGDFEGEINAYDKALELS
PNDAVIYNNRGNAKRKLEDYQSAIEDYNKSIEINPSSAAPYFNRGDIKYVLDDHKGAIDDYNLALEVDPDDPFLYAKRGD
LRVALHDYQGAIADYTKAIEINPQLAIAYYNRGEAKKEIGDLKGACEDWKKAAELGYEDAAKLVEEHCQ

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=347, Percent_Identity=26.8011527377522, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI32307148, Length=347, Percent_Identity=26.8011527377522, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI310123097, Length=442, Percent_Identity=23.9819004524887, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI310131789, Length=442, Percent_Identity=23.9819004524887, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI310110582, Length=442, Percent_Identity=23.9819004524887, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115532692, Length=296, Percent_Identity=28.3783783783784, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI115532690, Length=296, Percent_Identity=28.3783783783784, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319589, Length=320, Percent_Identity=23.75, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17647755, Length=328, Percent_Identity=27.4390243902439, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24585827, Length=328, Percent_Identity=27.4390243902439, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24585829, Length=328, Percent_Identity=27.4390243902439, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24647123, Length=263, Percent_Identity=25.0950570342205, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 62292; Mature: 62292

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHERNTAEEYIKRAKEKFLLKNYRGAISDCSKAIEIDPKDSSAYHIRGLARIISDEKELA
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCEECCCCCCCCHHHHHHHHHHCCHHHHH
RNDLYKASELGDKHAMEMLKKCFYPNVQNLIDLETKKIEKDASNFEHYIRRALLKEKFDP
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NGAIADYSKILEIDSERVDVYFYLALVKNKAGYPKQAIEDCRRALDIEAGNLLLKEYFEL
CCCHHHHHHHHHCCCCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
RNFVNYLLDGKSEPYQDAGDLIGVILVREPKITPSDSLEYNLRGIRKADLKNFPGAIDDF
HHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEECCCCCCHHHHCCCCCCHHHH
SKAIELEPRDCHLYVNRGIYRDMSGDPESAISDYCKAIEINPDFADAYYERGVTLRDSGH
HHHEECCCCCEEEEECCCEECCCCCCHHHHHHHHHHEEECCCCHHHHHHHCCCEEECCCC
QERAICDFLKAVDLNPKYSNAYLNIGSIKFHSSDVKGACAYWKKASELENKTADLLLDQE
HHHHHHHHHHHHCCCCCCCCEEEEECEEEEECCCCCHHHHHHHHHHHHHCHHHHHEECHH
CASQGVLASLSYYLNLGSDRCESGDFEGEINAYDKALELSPNDAVIYNNRGNAKRKLEDY
HHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCEEEECCCCEEEECCCCCHHHHHHHH
QSAIEDYNKSIEINPSSAAPYFNRGDIKYVLDDHKGAIDDYNLALEVDPDDPFLYAKRGD
HHHHHHCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEECCC
LRVALHDYQGAIADYTKAIEINPQLAIAYYNRGEAKKEIGDLKGACEDWKKAAELGYEDA
EEEEEECCCCHHHHHHEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
AKLVEEHCQ
HHHHHHHCC
>Mature Secondary Structure
MHERNTAEEYIKRAKEKFLLKNYRGAISDCSKAIEIDPKDSSAYHIRGLARIISDEKELA
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCEECCCCCCCCHHHHHHHHHHCCHHHHH
RNDLYKASELGDKHAMEMLKKCFYPNVQNLIDLETKKIEKDASNFEHYIRRALLKEKFDP
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NGAIADYSKILEIDSERVDVYFYLALVKNKAGYPKQAIEDCRRALDIEAGNLLLKEYFEL
CCCHHHHHHHHHCCCCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
RNFVNYLLDGKSEPYQDAGDLIGVILVREPKITPSDSLEYNLRGIRKADLKNFPGAIDDF
HHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEECCCCCCHHHHCCCCCCHHHH
SKAIELEPRDCHLYVNRGIYRDMSGDPESAISDYCKAIEINPDFADAYYERGVTLRDSGH
HHHEECCCCCEEEEECCCEECCCCCCHHHHHHHHHHEEECCCCHHHHHHHCCCEEECCCC
QERAICDFLKAVDLNPKYSNAYLNIGSIKFHSSDVKGACAYWKKASELENKTADLLLDQE
HHHHHHHHHHHHCCCCCCCCEEEEECEEEEECCCCCHHHHHHHHHHHHHCHHHHHEECHH
CASQGVLASLSYYLNLGSDRCESGDFEGEINAYDKALELSPNDAVIYNNRGNAKRKLEDY
HHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCEEEECCCCEEEECCCCCHHHHHHHH
QSAIEDYNKSIEINPSSAAPYFNRGDIKYVLDDHKGAIDDYNLALEVDPDDPFLYAKRGD
HHHHHHCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEECCC
LRVALHDYQGAIADYTKAIEINPQLAIAYYNRGEAKKEIGDLKGACEDWKKAAELGYEDA
EEEEEECCCCHHHHHHEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
AKLVEEHCQ
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]