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The map label for this gene is DHSS

Identifier: 33862316

GI number: 33862316

Start: 42402

End: 43550

Strand: Reverse

Name: DHSS

Synonym: PMT0043

Alternate gene names: NA

Gene position: 43550-42402 (Counterclockwise)

Preceding gene: 33862322

Following gene: 33862312

Centisome position: 1.81

GC content: 52.92

Gene sequence:

>1149_bases
GTGCAGGACAAACTCACCCTGATGATCCCGGGTCCTACACCGGTTCCCGAAACAGTACTCAAAGCCATGGGTCGCCACCC
CATCGGCCATCGCAGTGGAGAGTTTCAAGCCGTCGTTAGACATACCACCGAGCAGCTGCGCTGGCTGCATCAGACCAAAG
CAGATGTTCTAGTTATCACTGGAAGCGGTACCGCTGCGATGGAAGCAGGAATCATCAATACCCTCAGCTACGGCGACAAG
GTCCTCTGCGGCGACAACGGCAAGTTTGGACAGCGCTGGGTAAAGCTGGCTAAGGCTTACGGCCTGGACGTACAAGTGAT
AAAAGCAGACTGGGGACAACCGTTAGACCCAGAAGCCTTCAAAAAAGCACTGGAAGCAGATAATGGCAAAACAATAAAAG
CCGTAATTCTCACCCACTCGGAAACCTCAACCGGGGTCATTAACGACCTTGAAACCATCAGCAAATATGTCCGCACTCAT
GGCAAAGCACTAGCCATCGCTGATTGCGTTACAAGCCTTGGGGCCTGCAATGTCCCCATGGATTCTTGGGGTCTAGATGT
GGTTGCCTCCGGTTCCCAAAAGGGATACATGATGCCTCCAGGTCTCAGCTTCGTGGCCATGAGTGAACGAGCCTGGCAAG
CGCATCAACAATCGGATCTACCGAAGTTTTATCTCGATCTGGGGCCATACCGAAAAACTGCCGCTCAAGACAGCAATCCA
TTCACCCCTGCTGTGAATCTCTACTTCGCACTGGAATCTGCGCTGGGAATGATGCAGTCAGAAGGACTGGAAGCCATCTT
TGAACGTCATGCTCGCCATCGCGCAGCCGCTCAGGCCGGCATGAAGGCCATCTGCCTGCCACTGTATGCAGCTGAAGGAC
ACGGCAGCCCAGCGATCACCGCAGTCGCACCTGAGGGAATTGATGCAGAGCAACTGCGCAAAACTGTCAAAGAGAAATTC
GACATCCTGCTAGCAGGTGGACAGGATCATCTAAAAGGGAAGGTCTTCCGTATCGGCCATCTTGGATTCGTATGTGATAG
AGATATCCTCACTGCCATAGCTGCCATCGAATCCACCTTGCAATCTCTTGGCTTGCATAAAGGCAACATGGGAGATGGCC
TGGCAGCAGCAGCAGCAATTCTGAGATAA

Upstream 100 bases:

>100_bases
AAACCGGGAGCGTCAACCCCCTTGAATCAGCATCGGCGTGATCGATAAAAAACCCTTGCTTAGGTATTTTTGAGGATGGT
TCATTACTAAGCCTTAGGCC

Downstream 100 bases:

>100_bases
CAGTGCTCGCCAACAAAACGAACTAAAGCTGATCTAAACTGATCAAATGCGGGTGTAATTCAGTGGTAGAATGTCAGCTT
CCCAAGCTGAACGTCGCCGG

Product: soluble hydrogenase small subunit

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQDKLTLMIPGPTPVPETVLKAMGRHPIGHRSGEFQAVVRHTTEQLRWLHQTKADVLVITGSGTAAMEAGIINTLSYGDK
VLCGDNGKFGQRWVKLAKAYGLDVQVIKADWGQPLDPEAFKKALEADNGKTIKAVILTHSETSTGVINDLETISKYVRTH
GKALAIADCVTSLGACNVPMDSWGLDVVASGSQKGYMMPPGLSFVAMSERAWQAHQQSDLPKFYLDLGPYRKTAAQDSNP
FTPAVNLYFALESALGMMQSEGLEAIFERHARHRAAAQAGMKAICLPLYAAEGHGSPAITAVAPEGIDAEQLRKTVKEKF
DILLAGGQDHLKGKVFRIGHLGFVCDRDILTAIAAIESTLQSLGLHKGNMGDGLAAAAAILR

Sequences:

>Translated_382_residues
MQDKLTLMIPGPTPVPETVLKAMGRHPIGHRSGEFQAVVRHTTEQLRWLHQTKADVLVITGSGTAAMEAGIINTLSYGDK
VLCGDNGKFGQRWVKLAKAYGLDVQVIKADWGQPLDPEAFKKALEADNGKTIKAVILTHSETSTGVINDLETISKYVRTH
GKALAIADCVTSLGACNVPMDSWGLDVVASGSQKGYMMPPGLSFVAMSERAWQAHQQSDLPKFYLDLGPYRKTAAQDSNP
FTPAVNLYFALESALGMMQSEGLEAIFERHARHRAAAQAGMKAICLPLYAAEGHGSPAITAVAPEGIDAEQLRKTVKEKF
DILLAGGQDHLKGKVFRIGHLGFVCDRDILTAIAAIESTLQSLGLHKGNMGDGLAAAAAILR
>Mature_382_residues
MQDKLTLMIPGPTPVPETVLKAMGRHPIGHRSGEFQAVVRHTTEQLRWLHQTKADVLVITGSGTAAMEAGIINTLSYGDK
VLCGDNGKFGQRWVKLAKAYGLDVQVIKADWGQPLDPEAFKKALEADNGKTIKAVILTHSETSTGVINDLETISKYVRTH
GKALAIADCVTSLGACNVPMDSWGLDVVASGSQKGYMMPPGLSFVAMSERAWQAHQQSDLPKFYLDLGPYRKTAAQDSNP
FTPAVNLYFALESALGMMQSEGLEAIFERHARHRAAAQAGMKAICLPLYAAEGHGSPAITAVAPEGIDAEQLRKTVKEKF
DILLAGGQDHLKGKVFRIGHLGFVCDRDILTAIAAIESTLQSLGLHKGNMGDGLAAAAAILR

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=366, Percent_Identity=31.6939890710383, Blast_Score=155, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17536281, Length=347, Percent_Identity=31.1239193083574, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6321079, Length=370, Percent_Identity=26.2162162162162, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17530823, Length=347, Percent_Identity=29.3948126801153, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 41007; Mature: 41007

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDKLTLMIPGPTPVPETVLKAMGRHPIGHRSGEFQAVVRHTTEQLRWLHQTKADVLVIT
CCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
GSGTAAMEAGIINTLSYGDKVLCGDNGKFGQRWVKLAKAYGLDVQVIKADWGQPLDPEAF
CCCCHHHHHCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHH
KKALEADNGKTIKAVILTHSETSTGVINDLETISKYVRTHGKALAIADCVTSLGACNVPM
HHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCC
DSWGLDVVASGSQKGYMMPPGLSFVAMSERAWQAHQQSDLPKFYLDLGPYRKTAAQDSNP
CCCCCEEEECCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCEECCCCCCHHHHCCCCCC
FTPAVNLYFALESALGMMQSEGLEAIFERHARHRAAAQAGMKAICLPLYAAEGHGSPAIT
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEE
AVAPEGIDAEQLRKTVKEKFDILLAGGQDHLKGKVFRIGHLGFVCDRDILTAIAAIESTL
EECCCCCCHHHHHHHHHHHHCEEEECCCHHHCCEEEEEECCCCEECHHHHHHHHHHHHHH
QSLGLHKGNMGDGLAAAAAILR
HHHCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MQDKLTLMIPGPTPVPETVLKAMGRHPIGHRSGEFQAVVRHTTEQLRWLHQTKADVLVIT
CCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
GSGTAAMEAGIINTLSYGDKVLCGDNGKFGQRWVKLAKAYGLDVQVIKADWGQPLDPEAF
CCCCHHHHHCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHH
KKALEADNGKTIKAVILTHSETSTGVINDLETISKYVRTHGKALAIADCVTSLGACNVPM
HHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCC
DSWGLDVVASGSQKGYMMPPGLSFVAMSERAWQAHQQSDLPKFYLDLGPYRKTAAQDSNP
CCCCCEEEECCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCEECCCCCCHHHHCCCCCC
FTPAVNLYFALESALGMMQSEGLEAIFERHARHRAAAQAGMKAICLPLYAAEGHGSPAIT
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEE
AVAPEGIDAEQLRKTVKEKFDILLAGGQDHLKGKVFRIGHLGFVCDRDILTAIAAIESTL
EECCCCCCHHHHHHHHHHHHCEEEECCCHHHCCEEEEEECCCCEECHHHHHHHHHHHHHH
QSLGLHKGNMGDGLAAAAAILR
HHHCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]