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The map label for this gene is thiL [H]

Identifier: 33862302

GI number: 33862302

Start: 32003

End: 32986

Strand: Reverse

Name: thiL [H]

Synonym: PMT0029

Alternate gene names: 33862302

Gene position: 32986-32003 (Counterclockwise)

Preceding gene: 33862303

Following gene: 33862300

Centisome position: 1.37

GC content: 54.67

Gene sequence:

>984_bases
ATGGGCGAAACCCTAGCCCAACTTGGTGAAAACGAACTACTGCATCGACTAGCCCGCTTTGCTCCTGCTGGCCAACTTGA
CGACGACACAGCGCAAGTCCACACCAATGAGGGAGAACTCCTCATTAATACCGATGTCATGGTGGAAGGCATTCACTTCA
GCGAAGACACCACGACTCCAAAAGATGTTGGTTGGCGTTGCGTAACCGCCAACCTTTCCGACCTAGCAGCCAGTGGCGTT
GATCAGATTCTGGGTATCACTGTCGGACTTGTAGTCCCTCCAGAGACCCCCTGGGACTGGGTAGAGAAGGTTTATTTAGG
CATAGAAGCCGCATTGAAACAGTTTGGGGGGACCTTGCTGGGCGGCGACTGTTCCCGAGGGGATCAACGACTACTCGCAA
TCACCGCCCTGGGCACTCTCGGGCCAGTACGGTTGCACCGCTCCCAAGCCCAACCTGGAGATTCTCTTGTCGTCAGTGGT
CCCCATGGCCTCAGCCGTCTTGGCCTGGCCCTACTTCGCTCAGATCCACTGATAGAAGCAGCCCTGCTGCCAGACAAACT
CAAACAAAAAGCGATAGAAGCTCATCAACACCCTCAACCATGCCTGAAGGCACTCCACGCTCTTCAAACCTGTAAGCCTG
CTGAACTTCCATGGCGAGCTGGGGGCACCGACAGTAGTGACGGACTTCTGGCAGCGGTTCAAGGCCTTTGCAGAAGCAGC
GGTTGCCGGGCGATTCTTGATCCAACAGGCCTACCCAAAGACCCTGACTGGCCACTAGGCCAACACTGGGATAGCTGGTG
CCTAAATGGCGGAGAAGACTTTGAACTTATTCTCAGCCTGCCACCGAAATGGGCCACCGCTTGGCTGCAAGTTCTTCCAT
CAAGCCAAATCATTGGTGTCATGGAACAAGGCCCACCTCGGGTGGAATGGGCGCATGGCAAAGGAGAAGTGAGCAACTTC
TCAAGCTTCAAACATTTCCAATAA

Upstream 100 bases:

>100_bases
ACCGAGTTACTTAAAAAACTCGAAATTGGTGATCAAATCTTATCCATCAAAGTTGTCGATGGAGCTGATCGGCTGAAGCC
CCACGCCTGAGGACTTGTGT

Downstream 100 bases:

>100_bases
AGAAACAGAATAAACCCCTCGCTAATAGGAGGGGTTTATAACTCAAAAAGAAGCTAGAAGCTCAGAAAGTAGTAATCCTC
TGAAAGATCACTTCCAATTC

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MGETLAQLGENELLHRLARFAPAGQLDDDTAQVHTNEGELLINTDVMVEGIHFSEDTTTPKDVGWRCVTANLSDLAASGV
DQILGITVGLVVPPETPWDWVEKVYLGIEAALKQFGGTLLGGDCSRGDQRLLAITALGTLGPVRLHRSQAQPGDSLVVSG
PHGLSRLGLALLRSDPLIEAALLPDKLKQKAIEAHQHPQPCLKALHALQTCKPAELPWRAGGTDSSDGLLAAVQGLCRSS
GCRAILDPTGLPKDPDWPLGQHWDSWCLNGGEDFELILSLPPKWATAWLQVLPSSQIIGVMEQGPPRVEWAHGKGEVSNF
SSFKHFQ

Sequences:

>Translated_327_residues
MGETLAQLGENELLHRLARFAPAGQLDDDTAQVHTNEGELLINTDVMVEGIHFSEDTTTPKDVGWRCVTANLSDLAASGV
DQILGITVGLVVPPETPWDWVEKVYLGIEAALKQFGGTLLGGDCSRGDQRLLAITALGTLGPVRLHRSQAQPGDSLVVSG
PHGLSRLGLALLRSDPLIEAALLPDKLKQKAIEAHQHPQPCLKALHALQTCKPAELPWRAGGTDSSDGLLAAVQGLCRSS
GCRAILDPTGLPKDPDWPLGQHWDSWCLNGGEDFELILSLPPKWATAWLQVLPSSQIIGVMEQGPPRVEWAHGKGEVSNF
SSFKHFQ
>Mature_326_residues
GETLAQLGENELLHRLARFAPAGQLDDDTAQVHTNEGELLINTDVMVEGIHFSEDTTTPKDVGWRCVTANLSDLAASGVD
QILGITVGLVVPPETPWDWVEKVYLGIEAALKQFGGTLLGGDCSRGDQRLLAITALGTLGPVRLHRSQAQPGDSLVVSGP
HGLSRLGLALLRSDPLIEAALLPDKLKQKAIEAHQHPQPCLKALHALQTCKPAELPWRAGGTDSSDGLLAAVQGLCRSSG
CRAILDPTGLPKDPDWPLGQHWDSWCLNGGEDFELILSLPPKWATAWLQVLPSSQIIGVMEQGPPRVEWAHGKGEVSNFS
SFKHFQ

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=286, Percent_Identity=31.8181818181818, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35182; Mature: 35051

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGETLAQLGENELLHRLARFAPAGQLDDDTAQVHTNEGELLINTDVMVEGIHFSEDTTTP
CCHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEECCEEEEEEEECCCCCCC
KDVGWRCVTANLSDLAASGVDQILGITVGLVVPPETPWDWVEKVYLGIEAALKQFGGTLL
HHCCCEEEECCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEE
GGDCSRGDQRLLAITALGTLGPVRLHRSQAQPGDSLVVSGPHGLSRLGLALLRSDPLIEA
CCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHH
ALLPDKLKQKAIEAHQHPQPCLKALHALQTCKPAELPWRAGGTDSSDGLLAAVQGLCRSS
HHCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
GCRAILDPTGLPKDPDWPLGQHWDSWCLNGGEDFELILSLPPKWATAWLQVLPSSQIIGV
CCCEEECCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEEE
MEQGPPRVEWAHGKGEVSNFSSFKHFQ
CCCCCCCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GETLAQLGENELLHRLARFAPAGQLDDDTAQVHTNEGELLINTDVMVEGIHFSEDTTTP
CHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEECCEEEEEEEECCCCCCC
KDVGWRCVTANLSDLAASGVDQILGITVGLVVPPETPWDWVEKVYLGIEAALKQFGGTLL
HHCCCEEEECCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEE
GGDCSRGDQRLLAITALGTLGPVRLHRSQAQPGDSLVVSGPHGLSRLGLALLRSDPLIEA
CCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHH
ALLPDKLKQKAIEAHQHPQPCLKALHALQTCKPAELPWRAGGTDSSDGLLAAVQGLCRSS
HHCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
GCRAILDPTGLPKDPDWPLGQHWDSWCLNGGEDFELILSLPPKWATAWLQVLPSSQIIGV
CCCEEECCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEEE
MEQGPPRVEWAHGKGEVSNFSSFKHFQ
CCCCCCCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA