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The map label for this gene is murB [H]

Identifier: 33862299

GI number: 33862299

Start: 28356

End: 29279

Strand: Reverse

Name: murB [H]

Synonym: PMT0026

Alternate gene names: 33862299

Gene position: 29279-28356 (Counterclockwise)

Preceding gene: 33862300

Following gene: 33862298

Centisome position: 1.21

GC content: 54.76

Gene sequence:

>924_bases
ATGCCCACCCTCCCTGGCAGCCTGACCCTAGTGAAGGGGATCAAGCCCCAACCACTGGTTTCTCTTGCCAACTTCACGAG
CTGGCGCGTCGGAGGACCTGCGGAATGGTTTGCATCACCCAGCAGCGTGGAGGAACTACAGACACTGATTGCTTGGGCTT
ATGAACAAAAGATGCCCTGTCGAGTCATCGGAGCAGGATCAAACCTACTGATCAACGACACTGGCTTGCCGGGCCTGAGC
CTTTGCATGCGCAAACTCCAAGGGAGCGACCTAGATCCAAAGACTGGCATTGTCGAAGCCTTGGCCGGTGAACCAATCCC
CAACCTTTCCAAACGCGCCGCAAAGGTTGGCCTACATGGCCTGGAATGGGCCGTTGGAATTCCTGGAACAGTTGGTGGTG
CAGCCGTCATGAATGCTGGAGCCCAGGGCGGCTGCACAGCCGACTGGCTGGAATCTGTACAAGTCCTCGACCTCAATGGC
GAGGGCCCTTTTGAACTGAGCCGCCAAGAGCTTGACTACGCCTACCGACAAAGTCTCTTGCAGGAAAAAACACTCGTCGT
GCTCTCAGCCAGATTCCGCCTAGACCCCGGGCATGATCACAAGGAGCTCAATCAAATCACACAGCAAAACCTCACTCATC
GCACGACGACCCAGCCTTATCAATTGCCTAGTTGCGGAAGTGTCTTTCGCAACCCAGAACCCCTCAAAGCTGGTCGTCTA
ATCGAAGCGCTGGGTCTGAAAGGTCACCGCATTGGAGGAGCTGAAGTCTCCCCCATTCATGCCAACTTCATCGTCAATAT
TGGTGGAGCCACGGCTGCTGACATCAATCAAATGATCACCCTCATTCAGCAACGGGTACAGATGGCCCATGGAGTGATGC
TTCATCCTGAAGTGAAACGACTTGGTTTCGAAGCGACCGCTTAA

Upstream 100 bases:

>100_bases
TGCAAAAACACAGCCTCAAAGGTGACCTAGTCCTCGCCATGGGTGCAGGCAATATCAACAATCTATGGAGACAACTGACA
CATCTTGACAACGCAAAGAG

Downstream 100 bases:

>100_bases
TCTGCCCATTCCTCCAGCAATGCAATGGCAGGGTTCGGACTTCCCAATTTCGGCCAACTCACCGAAGCCTTCCGCAAGGC
CCAACAAATCCAACAAAACG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MPTLPGSLTLVKGIKPQPLVSLANFTSWRVGGPAEWFASPSSVEELQTLIAWAYEQKMPCRVIGAGSNLLINDTGLPGLS
LCMRKLQGSDLDPKTGIVEALAGEPIPNLSKRAAKVGLHGLEWAVGIPGTVGGAAVMNAGAQGGCTADWLESVQVLDLNG
EGPFELSRQELDYAYRQSLLQEKTLVVLSARFRLDPGHDHKELNQITQQNLTHRTTTQPYQLPSCGSVFRNPEPLKAGRL
IEALGLKGHRIGGAEVSPIHANFIVNIGGATAADINQMITLIQQRVQMAHGVMLHPEVKRLGFEATA

Sequences:

>Translated_307_residues
MPTLPGSLTLVKGIKPQPLVSLANFTSWRVGGPAEWFASPSSVEELQTLIAWAYEQKMPCRVIGAGSNLLINDTGLPGLS
LCMRKLQGSDLDPKTGIVEALAGEPIPNLSKRAAKVGLHGLEWAVGIPGTVGGAAVMNAGAQGGCTADWLESVQVLDLNG
EGPFELSRQELDYAYRQSLLQEKTLVVLSARFRLDPGHDHKELNQITQQNLTHRTTTQPYQLPSCGSVFRNPEPLKAGRL
IEALGLKGHRIGGAEVSPIHANFIVNIGGATAADINQMITLIQQRVQMAHGVMLHPEVKRLGFEATA
>Mature_306_residues
PTLPGSLTLVKGIKPQPLVSLANFTSWRVGGPAEWFASPSSVEELQTLIAWAYEQKMPCRVIGAGSNLLINDTGLPGLSL
CMRKLQGSDLDPKTGIVEALAGEPIPNLSKRAAKVGLHGLEWAVGIPGTVGGAAVMNAGAQGGCTADWLESVQVLDLNGE
GPFELSRQELDYAYRQSLLQEKTLVVLSARFRLDPGHDHKELNQITQQNLTHRTTTQPYQLPSCGSVFRNPEPLKAGRLI
EALGLKGHRIGGAEVSPIHANFIVNIGGATAADINQMITLIQQRVQMAHGVMLHPEVKRLGFEATA

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=308, Percent_Identity=25.6493506493506, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32928; Mature: 32797

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLPGSLTLVKGIKPQPLVSLANFTSWRVGGPAEWFASPSSVEELQTLIAWAYEQKMPC
CCCCCCCEEEECCCCCCCHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCE
RVIGAGSNLLINDTGLPGLSLCMRKLQGSDLDPKTGIVEALAGEPIPNLSKRAAKVGLHG
EEEECCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCC
LEWAVGIPGTVGGAAVMNAGAQGGCTADWLESVQVLDLNGEGPFELSRQELDYAYRQSLL
CEEEECCCCCCCCHHHHCCCCCCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
QEKTLVVLSARFRLDPGHDHKELNQITQQNLTHRTTTQPYQLPSCGSVFRNPEPLKAGRL
HHHHEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCHHHHH
IEALGLKGHRIGGAEVSPIHANFIVNIGGATAADINQMITLIQQRVQMAHGVMLHPEVKR
HHHHCCCCCCCCCCEECCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEECCHHHH
LGFEATA
CCCCCCC
>Mature Secondary Structure 
PTLPGSLTLVKGIKPQPLVSLANFTSWRVGGPAEWFASPSSVEELQTLIAWAYEQKMPC
CCCCCCEEEECCCCCCCHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCE
RVIGAGSNLLINDTGLPGLSLCMRKLQGSDLDPKTGIVEALAGEPIPNLSKRAAKVGLHG
EEEECCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCC
LEWAVGIPGTVGGAAVMNAGAQGGCTADWLESVQVLDLNGEGPFELSRQELDYAYRQSLL
CEEEECCCCCCCCHHHHCCCCCCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
QEKTLVVLSARFRLDPGHDHKELNQITQQNLTHRTTTQPYQLPSCGSVFRNPEPLKAGRL
HHHHEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCHHHHH
IEALGLKGHRIGGAEVSPIHANFIVNIGGATAADINQMITLIQQRVQMAHGVMLHPEVKR
HHHHCCCCCCCCCCEECCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEECCHHHH
LGFEATA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA