Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 326423988

GI number: 326423988

Start: 2383415

End: 2385028

Strand: Reverse

Name: hlyB [H]

Synonym: NA

Alternate gene names: 326423988

Gene position: 2385028-2383415 (Counterclockwise)

Preceding gene: 27365674

Following gene: 27365672

Centisome position: 72.67

GC content: 50.31

Gene sequence:

>1614_bases
ATGATGTCACTGTCTATTCGAGGGAAGGTGCTTGCACTATGCCTTCTATCGTTATTCGGATTTGCTAGCATGTTGTCCAT
TAGTGGTTCCACCCTGACCAATAACACTGAACAGGTTCGTCATATCGACAAACTGTACTATCCCGTCATGAACTCCGCAG
CGCTCAACTTAGTGCTGCTCTCCCAACTTACAGAGCGCTTTAACCTTGCGGTTACCCTAGGCGATGAAGAGCTGCTGGAT
TTGAACCGCACCACGCTTGAGGAAATCGTTGAGAACCTTGCGTTACAGGCGACATTGCAACCCGCGTTACGTGAACAAAC
CACCACGTTGCGTCGGCTTTTAAATACTTACTTTCAATCAACTTATGATGTGGCTCTCGGCATGATTGATGGCAACCTTG
ATCTCTCCGCCGCTGCGCAAAAAGCAGACGCCAATCGAAAGACGCTTGACGCACTAAAAAATCAGATGCAGCAATTTTCA
CATGCTCGAGTCGCGGATTTTGAACGCTCCGTGACGGAGCTTGAACAGAACAATGTCGCGGCCACTCAACTCATGCGTGT
GTTGGGCGCCACTGCATTGTTGCTCACCATTTTGATGGGTTGGTTTGTCACTCGCGGCATTAGACTAGATTTAGGCTCAT
TCGCAGAAAAGATGCGTGATATTGCCGACGGCGATGGCGACCTTACTGTTCGCATCCGTCACGAGAAAAATGATGAACTG
AAACCCGTTGTCGATTCATTCAACGCTTTTGTCACCAAACTTCAGCACAACGTCACGCAAACCATTGAGAACGTGAGCAA
ACTGGACCAAATATCCAGCACTTTGGTTGCTTCCAGCCACACTACGGCAGACTTGTCTGAACGCCAATATAAAGAGATTG
AAGATGTGTCCCATTCACTTGGCCAGTTGTTCGACGCAGCGAAACACATCGCCTCGCACGCCAGTGAAGCCTCCACATCC
GCCAATAGCGCGAGTGAAGAAGCTGCCAACGGCGAAGCGCAGGTCCAAAGCACGATTGTTGCCGTTCGAGAACTGACGGC
CGAAGTGAGAAATGCCTCACTCGTGGTTCAGCAATTGGATCAAAATACGCAAAACGCAGGCTCGATACTCGATGCCATCA
GTGCCATCGCCGAACAAACCAACCTGCTCGCCTTGAACGCAGCGATTGAAGCCGCCCGAGCAGGAGAACAGGGGCGTGGG
TTTGCCGTCGTTGCTGACGAAGTCAGAACACTGGCCTCTCGTACTCAATCTTCCACCCAAGAGATCCAATCCGTTTTGCA
TGAGTTGCAAGAACAAACCAAAACGGCCGCAAACATCATTTCTGAGAGCGCTTGCCGCGCAGAAGAGTGCGTGCAGAAAT
CGTTGGTCGCAGAGCAATCCTTACAACGCATCACCAGAGACGTTTCCGACATCAGCAGTAAAAATGGCCTGATTGCATTT
TCAACCGAAGAGCAGGAACGTGCCTCCAGTGACATTGAAGCCATCGTCGACAACATTCGCAGTATGGCACAGGGCACCGC
TGACAGCGTCGGCGAACTTGACGCAGTAGCACAAAACATCAACGCAATTACGGCAAACTTATCCGGTTTAACCGGACACT
TTAAGGTGAAGTAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:
NA

Sequences:

>Translated_537_residues
MMSLSIRGKVLALCLLSLFGFASMLSISGSTLTNNTEQVRHIDKLYYPVMNSAALNLVLLSQLTERFNLAVTLGDEELLD
LNRTTLEEIVENLALQATLQPALREQTTTLRRLLNTYFQSTYDVALGMIDGNLDLSAAAQKADANRKTLDALKNQMQQFS
HARVADFERSVTELEQNNVAATQLMRVLGATALLLTILMGWFVTRGIRLDLGSFAEKMRDIADGDGDLTVRIRHEKNDEL
KPVVDSFNAFVTKLQHNVTQTIENVSKLDQISSTLVASSHTTADLSERQYKEIEDVSHSLGQLFDAAKHIASHASEASTS
ANSASEEAANGEAQVQSTIVAVRELTAEVRNASLVVQQLDQNTQNAGSILDAISAIAEQTNLLALNAAIEAARAGEQGRG
FAVVADEVRTLASRTQSSTQEIQSVLHELQEQTKTAANIISESACRAEECVQKSLVAEQSLQRITRDVSDISSKNGLIAF
STEEQERASSDIEAIVDNIRSMAQGTADSVGELDAVAQNINAITANLSGLTGHFKVK
>Mature_537_residues
MMSLSIRGKVLALCLLSLFGFASMLSISGSTLTNNTEQVRHIDKLYYPVMNSAALNLVLLSQLTERFNLAVTLGDEELLD
LNRTTLEEIVENLALQATLQPALREQTTTLRRLLNTYFQSTYDVALGMIDGNLDLSAAAQKADANRKTLDALKNQMQQFS
HARVADFERSVTELEQNNVAATQLMRVLGATALLLTILMGWFVTRGIRLDLGSFAEKMRDIADGDGDLTVRIRHEKNDEL
KPVVDSFNAFVTKLQHNVTQTIENVSKLDQISSTLVASSHTTADLSERQYKEIEDVSHSLGQLFDAAKHIASHASEASTS
ANSASEEAANGEAQVQSTIVAVRELTAEVRNASLVVQQLDQNTQNAGSILDAISAIAEQTNLLALNAAIEAARAGEQGRG
FAVVADEVRTLASRTQSSTQEIQSVLHELQEQTKTAANIISESACRAEECVQKSLVAEQSLQRITRDVSDISSKNGLIAF
STEEQERASSDIEAIVDNIRSMAQGTADSVGELDAVAQNINAITANLSGLTGHFKVK

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=318, Percent_Identity=30.188679245283, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788195, Length=295, Percent_Identity=31.1864406779661, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787690, Length=252, Percent_Identity=34.5238095238095, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788194, Length=306, Percent_Identity=30.0653594771242, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789453, Length=339, Percent_Identity=28.023598820059, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58263; Mature: 58263

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSLSIRGKVLALCLLSLFGFASMLSISGSTLTNNTEQVRHIDKLYYPVMNSAALNLVLL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SQLTERFNLAVTLGDEELLDLNRTTLEEIVENLALQATLQPALREQTTTLRRLLNTYFQS
HHHHHHHCEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYDVALGMIDGNLDLSAAAQKADANRKTLDALKNQMQQFSHARVADFERSVTELEQNNVA
HHHHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ATQLMRVLGATALLLTILMGWFVTRGIRLDLGSFAEKMRDIADGDGDLTVRIRHEKNDEL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCH
KPVVDSFNAFVTKLQHNVTQTIENVSKLDQISSTLVASSHTTADLSERQYKEIEDVSHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GQLFDAAKHIASHASEASTSANSASEEAANGEAQVQSTIVAVRELTAEVRNASLVVQQLD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNTQNAGSILDAISAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQSSTQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
EIQSVLHELQEQTKTAANIISESACRAEECVQKSLVAEQSLQRITRDVSDISSKNGLIAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
STEEQERASSDIEAIVDNIRSMAQGTADSVGELDAVAQNINAITANLSGLTGHFKVK
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEECC
>Mature Secondary Structure
MMSLSIRGKVLALCLLSLFGFASMLSISGSTLTNNTEQVRHIDKLYYPVMNSAALNLVLL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SQLTERFNLAVTLGDEELLDLNRTTLEEIVENLALQATLQPALREQTTTLRRLLNTYFQS
HHHHHHHCEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYDVALGMIDGNLDLSAAAQKADANRKTLDALKNQMQQFSHARVADFERSVTELEQNNVA
HHHHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ATQLMRVLGATALLLTILMGWFVTRGIRLDLGSFAEKMRDIADGDGDLTVRIRHEKNDEL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCH
KPVVDSFNAFVTKLQHNVTQTIENVSKLDQISSTLVASSHTTADLSERQYKEIEDVSHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GQLFDAAKHIASHASEASTSANSASEEAANGEAQVQSTIVAVRELTAEVRNASLVVQQLD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNTQNAGSILDAISAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQSSTQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
EIQSVLHELQEQTKTAANIISESACRAEECVQKSLVAEQSLQRITRDVSDISSKNGLIAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
STEEQERASSDIEAIVDNIRSMAQGTADSVGELDAVAQNINAITANLSGLTGHFKVK
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]