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The map label for this gene is panE [H]

Identifier: 326423894

GI number: 326423894

Start: 1807125

End: 1808018

Strand: Reverse

Name: panE [H]

Synonym: NA

Alternate gene names: 326423894

Gene position: 1808018-1807125 (Counterclockwise)

Preceding gene: 27365163

Following gene: 27365161

Centisome position: 55.09

GC content: 48.1

Gene sequence:

>894_bases
TTGGTGAATATCCTCATTTTAGGCCCGGGAGCTGTTGGCTCACTTTGGGCGACAAAACTCAAACTCGCAGGGCACAATGT
CGCATTGTGGGGAAGAGGCGATGCATCTGAGCAACCCTTGCAACTAGATGATTCATCAGCCATGACGTTTAAACATCGTC
ACCTACCCTCTTTGCAAAGTGCTGACCTCATTTTGGTCACAGTGAAAGCATGGCAGGTGATGGCGGCGATTGAGCCTTTA
TTGCCACACATCCACTCAGATACCATCATCCTGCTGATGCACAACGGCATGGGAACCGCATCTCAGGTTGAAGAACAGCT
CACGCACAACCCAATCGTTGTCGCAACCACCACACATGGCGCGTATAAGCCTCATTCGCAGCAGGTCTTGCACACTGGGC
AAGGCATCACACAGTTGGGGGGCTTTAATACACAAGGTGCACAATGCGAGTTCCTTCAAGTGGTGCTCGATCACGCCTTA
CCGTCTGTCACATGGAATCCCAATATCCAACAGGCGCTTTGGACCAAACTGGCCATCAACTGCGCAATCAACCCATTAAC
AGCAATTCATCAATGTAAAAATGGCGAGTTGGCCGATGAGAGATTTCATCAACGGCTTGAGCGCATCACTCAAGAGTTGG
TTGACGTTATGGTCAAAGAAGGGATCGAGGTTACTTTCGATACCTTGCAGCAAACGATCATGAACGTGATTCATGCAACA
GCGGAAAACTACTCCTCGATGCGACAAGATGTTTTCCATCAACGCCGCACTGAAATCGACTATATCACTGGATATTTGTT
GCAAGCAGCGCATAAACACCAGATTGATGCAGCGGAAAACGCTAAACTTTATCAACACATCAAACAGATTGAACAAAGCT
GGACAGAACAATGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:
NA

Sequences:

>Translated_297_residues
MVNILILGPGAVGSLWATKLKLAGHNVALWGRGDASEQPLQLDDSSAMTFKHRHLPSLQSADLILVTVKAWQVMAAIEPL
LPHIHSDTIILLMHNGMGTASQVEEQLTHNPIVVATTTHGAYKPHSQQVLHTGQGITQLGGFNTQGAQCEFLQVVLDHAL
PSVTWNPNIQQALWTKLAINCAINPLTAIHQCKNGELADERFHQRLERITQELVDVMVKEGIEVTFDTLQQTIMNVIHAT
AENYSSMRQDVFHQRRTEIDYITGYLLQAAHKHQIDAAENAKLYQHIKQIEQSWTEQ
>Mature_297_residues
MVNILILGPGAVGSLWATKLKLAGHNVALWGRGDASEQPLQLDDSSAMTFKHRHLPSLQSADLILVTVKAWQVMAAIEPL
LPHIHSDTIILLMHNGMGTASQVEEQLTHNPIVVATTTHGAYKPHSQQVLHTGQGITQLGGFNTQGAQCEFLQVVLDHAL
PSVTWNPNIQQALWTKLAINCAINPLTAIHQCKNGELADERFHQRLERITQELVDVMVKEGIEVTFDTLQQTIMNVIHAT
AENYSSMRQDVFHQRRTEIDYITGYLLQAAHKHQIDAAENAKLYQHIKQIEQSWTEQ

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=298, Percent_Identity=40.2684563758389, Blast_Score=203, Evalue=9e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33151; Mature: 33151

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNILILGPGAVGSLWATKLKLAGHNVALWGRGDASEQPLQLDDSSAMTFKHRHLPSLQS
CEEEEEECCCCHHHHHHHHHEECCCCEEEEECCCCCCCCEECCCCCCCEEHHHCCCCCCC
ADLILVTVKAWQVMAAIEPLLPHIHSDTIILLMHNGMGTASQVEEQLTHNPIVVATTTHG
CCEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEECCC
AYKPHSQQVLHTGQGITQLGGFNTQGAQCEFLQVVLDHALPSVTWNPNIQQALWTKLAIN
CCCCCHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
CAINPLTAIHQCKNGELADERFHQRLERITQELVDVMVKEGIEVTFDTLQQTIMNVIHAT
HCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AENYSSMRQDVFHQRRTEIDYITGYLLQAAHKHQIDAAENAKLYQHIKQIEQSWTEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNILILGPGAVGSLWATKLKLAGHNVALWGRGDASEQPLQLDDSSAMTFKHRHLPSLQS
CEEEEEECCCCHHHHHHHHHEECCCCEEEEECCCCCCCCEECCCCCCCEEHHHCCCCCCC
ADLILVTVKAWQVMAAIEPLLPHIHSDTIILLMHNGMGTASQVEEQLTHNPIVVATTTHG
CCEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEECCC
AYKPHSQQVLHTGQGITQLGGFNTQGAQCEFLQVVLDHALPSVTWNPNIQQALWTKLAIN
CCCCCHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
CAINPLTAIHQCKNGELADERFHQRLERITQELVDVMVKEGIEVTFDTLQQTIMNVIHAT
HCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AENYSSMRQDVFHQRRTEIDYITGYLLQAAHKHQIDAAENAKLYQHIKQIEQSWTEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]