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The map label for this gene is phoR [H]

Identifier: 326423716

GI number: 326423716

Start: 465883

End: 467181

Strand: Reverse

Name: phoR [H]

Synonym: NA

Alternate gene names: 326423716

Gene position: 467181-465883 (Counterclockwise)

Preceding gene: 27363935

Following gene: 27363933

Centisome position: 14.24

GC content: 47.42

Gene sequence:

>1299_bases
GTGGTTGAAAGATTAACTTGGAAAAAGCTGGCATGGGAGCTGGCTTTTTTTTACACCCCCTGGGTGATTGTTGGGTGGAT
ATTCGGCTATATGCCGTGGCTGCTTTTGGTGGCGACGGCTTTGCAGCTTGGTTGGCATTTACACAATCAGGTACGTTTGT
CTGCGTGGCTCTGGGATGAAAAGCGTTTAACGCCGCCATCGGGCAGTGGTAATTGGGAATCGCTGTTTAATGGCCTTTAT
CGCTTACAGCAAAGGCAGCGACGCAAGCGTAAAGAACTGACGAATTTGATCCGTCGTTTCCGCAATGGTGCAGAATCGTT
GCCGGATGCGGTTGTGGTGTTTCGTGCGGAGGGCAACATTGTCTGGTGTAACAAGCTGGCGCAACATCTATTAGGTTTCC
ATTGGCCTGAAGATTCTGGTCAGCCTATTTCTAATCTTCTTCGCACTCCTGACTTTATTAAATATCTCTCTGGTAATGAT
TTTTCTGAACCGTTGGAAATGTGCTCGCCGCTAAACGTTGAACGTACGCTGGAACTGCGTATTGTTCCTTATACTGAAGG
TGAGCACTTGATGGTGGTGCGTGACGTGACGCAGTTGAAACAGCTAGAAGGCATGCGTCGAAACTTTTTTGCTAATGTTT
CCCATGAGTTACGTACGCCAATGACGGTGCTTCAGGGTTATCTCGAAATGACCGAAGACCCGGACATGTTGGTTGGCCCC
ATGTGGGGCAAAGCCCATCGTGTGATGACGGAACAGCTGAATCGAATGAACAGTTTAGTGAATCAGTTGTTAACCTTATC
CAAGATCGAAGCGTCGCCAATTCATGAGTTGGATGAAGTGGTTGATGTGCCCGCCATGCTGGAAGTGCTAGAGAAAGAAG
CGGTAAGTTTGAGTGGTGATAATCAGCACGCCATCTCTTTCCAAGTGGATAAAGCGCTTAAAGTCTATGCCGATGAAGAT
CAACTGCGCAGTGCTATTTCGAACCTAGTATACAATGCCGTGAAGTACACACCTGCTGGTGCAAGCGTACAGGTTCGTTG
GTATCGCAATAGCAAGGGTGCTTGCCTAGAAGTGGAAGACAGTGGTGATGGTATTGAACCGCAACATATCCATCGTCTAA
CGGAGCGTTTTTATCGTGTTGACAAAGCACGCTCTCGTGACACCGGAGGCAGTGGTTTAGGTCTAGCGATTGTAAAACAT
GCTTTGACTCATCACGACACTCATTTGGATATCCAAAGTAAAGTTGGCAGTGGCAGTAAGTTTTCATTCGTTTTACCGGC
AAAATTGGTGGCGAAATGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: phosphate regulon sensor kinase PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:
NA

Sequences:

>Translated_432_residues
MVERLTWKKLAWELAFFYTPWVIVGWIFGYMPWLLLVATALQLGWHLHNQVRLSAWLWDEKRLTPPSGSGNWESLFNGLY
RLQQRQRRKRKELTNLIRRFRNGAESLPDAVVVFRAEGNIVWCNKLAQHLLGFHWPEDSGQPISNLLRTPDFIKYLSGND
FSEPLEMCSPLNVERTLELRIVPYTEGEHLMVVRDVTQLKQLEGMRRNFFANVSHELRTPMTVLQGYLEMTEDPDMLVGP
MWGKAHRVMTEQLNRMNSLVNQLLTLSKIEASPIHELDEVVDVPAMLEVLEKEAVSLSGDNQHAISFQVDKALKVYADED
QLRSAISNLVYNAVKYTPAGASVQVRWYRNSKGACLEVEDSGDGIEPQHIHRLTERFYRVDKARSRDTGGSGLGLAIVKH
ALTHHDTHLDIQSKVGSGSKFSFVLPAKLVAK
>Mature_432_residues
MVERLTWKKLAWELAFFYTPWVIVGWIFGYMPWLLLVATALQLGWHLHNQVRLSAWLWDEKRLTPPSGSGNWESLFNGLY
RLQQRQRRKRKELTNLIRRFRNGAESLPDAVVVFRAEGNIVWCNKLAQHLLGFHWPEDSGQPISNLLRTPDFIKYLSGND
FSEPLEMCSPLNVERTLELRIVPYTEGEHLMVVRDVTQLKQLEGMRRNFFANVSHELRTPMTVLQGYLEMTEDPDMLVGP
MWGKAHRVMTEQLNRMNSLVNQLLTLSKIEASPIHELDEVVDVPAMLEVLEKEAVSLSGDNQHAISFQVDKALKVYADED
QLRSAISNLVYNAVKYTPAGASVQVRWYRNSKGACLEVEDSGDGIEPQHIHRLTERFYRVDKARSRDTGGSGLGLAIVKH
ALTHHDTHLDIQSKVGSGSKFSFVLPAKLVAK

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=433, Percent_Identity=60.0461893764434, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=29.8804780876494, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786783, Length=273, Percent_Identity=31.8681318681319, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788549, Length=365, Percent_Identity=24.6575342465753, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=30.1801801801802, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788713, Length=405, Percent_Identity=23.7037037037037, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=28.3842794759825, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=373, Percent_Identity=24.6648793565684, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=348, Percent_Identity=25, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=26.5217391304348, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=27.1551724137931, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789808, Length=249, Percent_Identity=28.5140562248996, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790551, Length=216, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=28.8793103448276, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789403, Length=231, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788279, Length=261, Percent_Identity=26.0536398467433, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=25.6521739130435, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=226, Percent_Identity=27.8761061946903, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=28.9855072463768, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49407; Mature: 49407

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERLTWKKLAWELAFFYTPWVIVGWIFGYMPWLLLVATALQLGWHLHNQVRLSAWLWDE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECC
KRLTPPSGSGNWESLFNGLYRLQQRQRRKRKELTNLIRRFRNGAESLPDAVVVFRAEGNI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEEECCCCE
VWCNKLAQHLLGFHWPEDSGQPISNLLRTPDFIKYLSGNDFSEPLEMCSPLNVERTLELR
EEHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHCCCCCCCHHHHCCCCCCCEEEEEE
IVPYTEGEHLMVVRDVTQLKQLEGMRRNFFANVSHELRTPMTVLQGYLEMTEDPDMLVGP
EEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCCCEEEEC
MWGKAHRVMTEQLNRMNSLVNQLLTLSKIEASPIHELDEVVDVPAMLEVLEKEAVSLSGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCC
NQHAISFQVDKALKVYADEDQLRSAISNLVYNAVKYTPAGASVQVRWYRNSKGACLEVED
CCEEEEEEECCHHHEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEC
SGDGIEPQHIHRLTERFYRVDKARSRDTGGSGLGLAIVKHALTHHDTHLDIQSKVGSGSK
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHCCCCCC
FSFVLPAKLVAK
EEEECCHHHHCC
>Mature Secondary Structure
MVERLTWKKLAWELAFFYTPWVIVGWIFGYMPWLLLVATALQLGWHLHNQVRLSAWLWDE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECC
KRLTPPSGSGNWESLFNGLYRLQQRQRRKRKELTNLIRRFRNGAESLPDAVVVFRAEGNI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEEECCCCE
VWCNKLAQHLLGFHWPEDSGQPISNLLRTPDFIKYLSGNDFSEPLEMCSPLNVERTLELR
EEHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHCCCCCCCHHHHCCCCCCCEEEEEE
IVPYTEGEHLMVVRDVTQLKQLEGMRRNFFANVSHELRTPMTVLQGYLEMTEDPDMLVGP
EEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCCCEEEEC
MWGKAHRVMTEQLNRMNSLVNQLLTLSKIEASPIHELDEVVDVPAMLEVLEKEAVSLSGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCC
NQHAISFQVDKALKVYADEDQLRSAISNLVYNAVKYTPAGASVQVRWYRNSKGACLEVED
CCEEEEEEECCHHHEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEC
SGDGIEPQHIHRLTERFYRVDKARSRDTGGSGLGLAIVKHALTHHDTHLDIQSKVGSGSK
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHCCCCCC
FSFVLPAKLVAK
EEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3550103; 9278503; 2187152; 8391104 [H]