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The map label for this gene is treB [H]

Identifier: 326423682

GI number: 326423682

Start: 280039

End: 281475

Strand: Reverse

Name: treB [H]

Synonym: NA

Alternate gene names: 326423682

Gene position: 281475-280039 (Counterclockwise)

Preceding gene: 27363768

Following gene: 27363766

Centisome position: 8.58

GC content: 49.41

Gene sequence:

>1437_bases
GTGGACAGAGTTATGAGTAAGATAGCGCGCAAGGACGTTGAACGTCTCATCGAGCTAGTCGGAGGAAGCGACAACATCGC
CAGTGTCAGCCACTGTTTGACACGCCTTCGCTTTGTGTTGAACGACACGTCGGCCGCCGATGTTAAGCAAATCGAAACAT
TGTCGATGGTCAAAGGATGCTTTACCAACGCGGGTCAATTTCAAGTGGTGATTGGCACGGAAGTTGATGCTGTCTATAAA
GTGTTGCTTGAGATTTCAGGTAAATCGGAAGCGAGCAAAGACGATGCGAAATTGGCGGCTCGTCAAAACATGAACATCAT
TGAGCGCGGAATCTCCCATCTTGCTGAAATTTTTGTCCCTCTGCTCCCTGCGATCATCACTGGTGGTTTAATCCTTGGTT
TCCGTAATGTGATTGGTGACATCAAGATGTTTGATGGCCAGACATTGACGGAGATTAGCCAGTTTTGGGCAACGGTTCAC
TCCTTTTTATGGTTGATTGGCGAAGCTATTTTCTTCTTCTTACCAGTAGGGGTGTGCTGGTCTACCGTGAAGAAACTCGG
CGGGACACCGATTTTGGGCATTACACTTGGTGTAACACTGGTTTCACCGCAGCTCATGAACGCCTACTTAATAGGTAAAC
AAGCCCCAGAAGTGTGGGACTTTGGTCTGTTTGTGATTGAAAAGGTCGGCTATCAAGCGCAGGTGATCCCAGCCATGTTG
GCAGGTGTTGCGTTGGCTTTCATTGAAACTAACCTAAAACGTATCGTCCCTTCTTACCTCTACCTCGTGGTGGTGCCGTT
TGTCTCGATCATCCTATCCGTTATTCTTGCCCATTCTTTGATTGGCCCGTTTGGCCGTGTGCTGGGTGATGGCGTGGCAT
TTGCGGCAAAAGCGGCCATGACGGGCGACTTTGCAGTGTTAGGCTCAATGATTTTTGGCTTCTTGTACGCACCACTTGTG
ATCACCGGTATTCACCATACAACCAACGCGGTGGATTTGCAGTTGATGCAAGAGATGGGTGGTACGCCAATTTGGCCGCT
GATTGCGTTGTCAAATATCGCACAGGCGTCTGCCGTTGTTGGCATCATCATTATCAGTAAAAAACATGGCGAGCGTGACA
TCTCTGTACCCGCTGCGATTTCAGCCTATTTAGGTGTGACTGAGCCTGCCATGTACGGCATCAACCTCAAGTACAAGTTC
CCTATGCTTAGCGCGATGATTGGTAGTGCTGTCGCGGCCGCAATTTGTGGTGGTGCTGGTGTGATGGCAAATGGCATCGG
GGTGGGTGGCCTACCTGGCATTCTCTCAATTCAACCACAATTTTGGGGAATTTACGCACTGGCGATGTTGACCGCCATTG
TGTTGCCAGCAGCCCTCACTTTAGTGTTTTACAAGCGAGCAGAAGCCAAAGGCGAACTCGAACCGGTAAACGCATAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: PTS system, trehalose-specific IIB component

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:
NA

Sequences:

>Translated_478_residues
MDRVMSKIARKDVERLIELVGGSDNIASVSHCLTRLRFVLNDTSAADVKQIETLSMVKGCFTNAGQFQVVIGTEVDAVYK
VLLEISGKSEASKDDAKLAARQNMNIIERGISHLAEIFVPLLPAIITGGLILGFRNVIGDIKMFDGQTLTEISQFWATVH
SFLWLIGEAIFFFLPVGVCWSTVKKLGGTPILGITLGVTLVSPQLMNAYLIGKQAPEVWDFGLFVIEKVGYQAQVIPAML
AGVALAFIETNLKRIVPSYLYLVVVPFVSIILSVILAHSLIGPFGRVLGDGVAFAAKAAMTGDFAVLGSMIFGFLYAPLV
ITGIHHTTNAVDLQLMQEMGGTPIWPLIALSNIAQASAVVGIIIISKKHGERDISVPAAISAYLGVTEPAMYGINLKYKF
PMLSAMIGSAVAAAICGGAGVMANGIGVGGLPGILSIQPQFWGIYALAMLTAIVLPAALTLVFYKRAEAKGELEPVNA
>Mature_478_residues
MDRVMSKIARKDVERLIELVGGSDNIASVSHCLTRLRFVLNDTSAADVKQIETLSMVKGCFTNAGQFQVVIGTEVDAVYK
VLLEISGKSEASKDDAKLAARQNMNIIERGISHLAEIFVPLLPAIITGGLILGFRNVIGDIKMFDGQTLTEISQFWATVH
SFLWLIGEAIFFFLPVGVCWSTVKKLGGTPILGITLGVTLVSPQLMNAYLIGKQAPEVWDFGLFVIEKVGYQAQVIPAML
AGVALAFIETNLKRIVPSYLYLVVVPFVSIILSVILAHSLIGPFGRVLGDGVAFAAKAAMTGDFAVLGSMIFGFLYAPLV
ITGIHHTTNAVDLQLMQEMGGTPIWPLIALSNIAQASAVVGIIIISKKHGERDISVPAAISAYLGVTEPAMYGINLKYKF
PMLSAMIGSAVAAAICGGAGVMANGIGVGGLPGILSIQPQFWGIYALAMLTAIVLPAALTLVFYKRAEAKGELEPVNA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=471, Percent_Identity=69.4267515923567, Blast_Score=656, Evalue=0.0,
Organism=Escherichia coli, GI1790159, Length=437, Percent_Identity=26.3157894736842, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI48994906, Length=431, Percent_Identity=28.0742459396752, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788769, Length=424, Percent_Identity=25.7075471698113, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 50894; Mature: 50894

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVMSKIARKDVERLIELVGGSDNIASVSHCLTRLRFVLNDTSAADVKQIETLSMVKGC
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FTNAGQFQVVIGTEVDAVYKVLLEISGKSEASKDDAKLAARQNMNIIERGISHLAEIFVP
HCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLPAIITGGLILGFRNVIGDIKMFDGQTLTEISQFWATVHSFLWLIGEAIFFFLPVGVCW
HHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STVKKLGGTPILGITLGVTLVSPQLMNAYLIGKQAPEVWDFGLFVIEKVGYQAQVIPAML
HHHHHHCCCCEEHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
AGVALAFIETNLKRIVPSYLYLVVVPFVSIILSVILAHSLIGPFGRVLGDGVAFAAKAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TGDFAVLGSMIFGFLYAPLVITGIHHTTNAVDLQLMQEMGGTPIWPLIALSNIAQASAVV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHE
GIIIISKKHGERDISVPAAISAYLGVTEPAMYGINLKYKFPMLSAMIGSAVAAAICGGAG
EEEEEECCCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEECHHHHHHHHHHHHHHHHCCCH
VMANGIGVGGLPGILSIQPQFWGIYALAMLTAIVLPAALTLVFYKRAEAKGELEPVNA
HHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDRVMSKIARKDVERLIELVGGSDNIASVSHCLTRLRFVLNDTSAADVKQIETLSMVKGC
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FTNAGQFQVVIGTEVDAVYKVLLEISGKSEASKDDAKLAARQNMNIIERGISHLAEIFVP
HCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLPAIITGGLILGFRNVIGDIKMFDGQTLTEISQFWATVHSFLWLIGEAIFFFLPVGVCW
HHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STVKKLGGTPILGITLGVTLVSPQLMNAYLIGKQAPEVWDFGLFVIEKVGYQAQVIPAML
HHHHHHCCCCEEHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
AGVALAFIETNLKRIVPSYLYLVVVPFVSIILSVILAHSLIGPFGRVLGDGVAFAAKAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TGDFAVLGSMIFGFLYAPLVITGIHHTTNAVDLQLMQEMGGTPIWPLIALSNIAQASAVV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHE
GIIIISKKHGERDISVPAAISAYLGVTEPAMYGINLKYKFPMLSAMIGSAVAAAICGGAG
EEEEEECCCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEECHHHHHHHHHHHHHHHHCCCH
VMANGIGVGGLPGILSIQPQFWGIYALAMLTAIVLPAALTLVFYKRAEAKGELEPVNA
HHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]