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The map label for this gene is yhdP [H]

Identifier: 32267371

GI number: 32267371

Start: 1793147

End: 1794469

Strand: Direct

Name: yhdP [H]

Synonym: HH1872

Alternate gene names: 32267371

Gene position: 1793147-1794469 (Clockwise)

Preceding gene: 32267370

Following gene: NA

Centisome position: 99.67

GC content: 33.94

Gene sequence:

>1323_bases
TTGGACCCGTATTCGTCCATTTTAATGCTTATTTTGGCATTATTTTTAGTATTTCTTAATGCCTTTTTTGTGCTTTCAGA
GTTTGCTATTGTTAAAATACGAAAATCAAAGCTAGAGGAACTTGCGAAAAATGAAGTTAAAAATGCTTCTCTTGCTTTAA
AAATTACTCATTCGCTTGATACATATTTGAGTGCAACACAACTTGGCATCACTCTTGCTTCTCTCGCACTAGGTTGGATT
AGTGAAAATGCTTTTGTTAAGCTTATAAGTATTCCATTTGGTTATCTTTTGGAATCTTCTCCTCTTTTAGTGCATTCTAT
TGCATCAATGATTGCTTTTGTTTTCGTAACGCTTCTTCACGTTGTGCTTGGAGAGCTTGTGCCAAAGTCAGTTGCCATTG
CCAAAACAGAATCGGTCGTGCTTCTCGTTGCCAAACCACTTTATACATTTCGGATTATCTTTTCTCCATTGATTAAGCTT
TTTGATTTGCTTGCAGCATTTTTTCTTAAGTTCATTAACATCTCGCCTGCACGTGAAAATGAAGCTGTCCATTCCGATGA
GGAACTTAAAATTATTATAGGTGAAAGTCTTAAAGAAGGCTATATAGATTCTATAGAGGGTGAGATTATTAAAAACGCTG
TTGATTTCTCTGATACCCTTGCTAGAGAAATTATGACGCCCAGAAAAGATATGATATGTTTAAATGCACAAGATGGATAT
GAAAAAAATATTGATATTATTTTGCAAACGAATCACACGCGCTATCCTTACTATCAAGATTCCAAAGATAATATTCTAGG
TATGATACATATCCGCGATTTATTTGAAAACGCAATAAAAGGCAAAGAGCATAATCTCTCTAAACTTGTCCGCAATATGA
TTATTGTGCCAGAGAGCGCACATATCTCTGAAATTTTAAATACAATGAATCGTCAACAAGTCCATACTGCACTTGTTGTT
GATGAATACGGTGGCACTTCTGGGCTTTTGACAATGGAAGATATTATTGAGGAAATTATGGGGGATATTTCTGATGAACA
CGACCTCAAAATTGAAGATATGAGGCAAATTGATGCGCAAACTTATGAATTTGATGGAAAACTTGAAATAAGTGATATTG
AAGAAATGCTTGACATTACTTTTAAAAATACAAATGACCATATCACTATTGGAGGCTATGTATTTGGATTATTTGGGCGA
TTACCTATGATGAAAGATAAAATTACTGATGAACATTGCATTTTTGAAGTGCTTGAAATGGAAGGTGCAAGAATTAAAAA
ATTAAAAGTTACTTATACACCAAAAATAACATCAACGCTTTGA

Upstream 100 bases:

>100_bases
GTTACTTATTATGTGATTACTAGTCTTGGCTTTAGTATTTAGTTTTTTAAAAGATTTGATTGATTACAATTAAATCTTTA
CTTTTAGACAAGGAGATTTT

Downstream 100 bases:

>100_bases
TTTTTCTCTTACCATTTGCACAAGGGCAATAGCATTCTCGCGTGGTAAGTCTGGAAGCATTCCGTGTCCTAAATTAAAGA
TATGTCCCTTTTCTTTTCCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MDPYSSILMLILALFLVFLNAFFVLSEFAIVKIRKSKLEELAKNEVKNASLALKITHSLDTYLSATQLGITLASLALGWI
SENAFVKLISIPFGYLLESSPLLVHSIASMIAFVFVTLLHVVLGELVPKSVAIAKTESVVLLVAKPLYTFRIIFSPLIKL
FDLLAAFFLKFINISPARENEAVHSDEELKIIIGESLKEGYIDSIEGEIIKNAVDFSDTLAREIMTPRKDMICLNAQDGY
EKNIDIILQTNHTRYPYYQDSKDNILGMIHIRDLFENAIKGKEHNLSKLVRNMIIVPESAHISEILNTMNRQQVHTALVV
DEYGGTSGLLTMEDIIEEIMGDISDEHDLKIEDMRQIDAQTYEFDGKLEISDIEEMLDITFKNTNDHITIGGYVFGLFGR
LPMMKDKITDEHCIFEVLEMEGARIKKLKVTYTPKITSTL

Sequences:

>Translated_440_residues
MDPYSSILMLILALFLVFLNAFFVLSEFAIVKIRKSKLEELAKNEVKNASLALKITHSLDTYLSATQLGITLASLALGWI
SENAFVKLISIPFGYLLESSPLLVHSIASMIAFVFVTLLHVVLGELVPKSVAIAKTESVVLLVAKPLYTFRIIFSPLIKL
FDLLAAFFLKFINISPARENEAVHSDEELKIIIGESLKEGYIDSIEGEIIKNAVDFSDTLAREIMTPRKDMICLNAQDGY
EKNIDIILQTNHTRYPYYQDSKDNILGMIHIRDLFENAIKGKEHNLSKLVRNMIIVPESAHISEILNTMNRQQVHTALVV
DEYGGTSGLLTMEDIIEEIMGDISDEHDLKIEDMRQIDAQTYEFDGKLEISDIEEMLDITFKNTNDHITIGGYVFGLFGR
LPMMKDKITDEHCIFEVLEMEGARIKKLKVTYTPKITSTL
>Mature_440_residues
MDPYSSILMLILALFLVFLNAFFVLSEFAIVKIRKSKLEELAKNEVKNASLALKITHSLDTYLSATQLGITLASLALGWI
SENAFVKLISIPFGYLLESSPLLVHSIASMIAFVFVTLLHVVLGELVPKSVAIAKTESVVLLVAKPLYTFRIIFSPLIKL
FDLLAAFFLKFINISPARENEAVHSDEELKIIIGESLKEGYIDSIEGEIIKNAVDFSDTLAREIMTPRKDMICLNAQDGY
EKNIDIILQTNHTRYPYYQDSKDNILGMIHIRDLFENAIKGKEHNLSKLVRNMIIVPESAHISEILNTMNRQQVHTALVV
DEYGGTSGLLTMEDIIEEIMGDISDEHDLKIEDMRQIDAQTYEFDGKLEISDIEEMLDITFKNTNDHITIGGYVFGLFGR
LPMMKDKITDEHCIFEVLEMEGARIKKLKVTYTPKITSTL

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=386, Percent_Identity=39.3782383419689, Blast_Score=273, Evalue=3e-73,
Organism=Escherichia coli, GI1790664, Length=425, Percent_Identity=24, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1786879, Length=246, Percent_Identity=30.8943089430894, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI145693175, Length=414, Percent_Identity=22.7053140096618, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI87082033, Length=399, Percent_Identity=22.8070175438596, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788119, Length=397, Percent_Identity=21.4105793450882, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49674; Mature: 49674

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPYSSILMLILALFLVFLNAFFVLSEFAIVKIRKSKLEELAKNEVKNASLALKITHSLD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHH
TYLSATQLGITLASLALGWISENAFVKLISIPFGYLLESSPLLVHSIASMIAFVFVTLLH
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VVLGELVPKSVAIAKTESVVLLVAKPLYTFRIIFSPLIKLFDLLAAFFLKFINISPAREN
HHHHHHCCCCEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EAVHSDEELKIIIGESLKEGYIDSIEGEIIKNAVDFSDTLAREIMTPRKDMICLNAQDGY
CCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEECCCCC
EKNIDIILQTNHTRYPYYQDSKDNILGMIHIRDLFENAIKGKEHNLSKLVRNMIIVPESA
CCCCEEEEEECCCCCCCEECCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHEECCCCH
HISEILNTMNRQQVHTALVVDEYGGTSGLLTMEDIIEEIMGDISDEHDLKIEDMRQIDAQ
HHHHHHHHHHHHHHHHEEEEECCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHCCH
TYEFDGKLEISDIEEMLDITFKNTNDHITIGGYVFGLFGRLPMMKDKITDEHCIFEVLEM
HEECCCEEEHHHHHHHHHEEEECCCCEEEEHHHHHHHHCCCCCHHHHCCCHHHHHHHHHC
EGARIKKLKVTYTPKITSTL
CCCEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MDPYSSILMLILALFLVFLNAFFVLSEFAIVKIRKSKLEELAKNEVKNASLALKITHSLD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHH
TYLSATQLGITLASLALGWISENAFVKLISIPFGYLLESSPLLVHSIASMIAFVFVTLLH
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VVLGELVPKSVAIAKTESVVLLVAKPLYTFRIIFSPLIKLFDLLAAFFLKFINISPAREN
HHHHHHCCCCEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EAVHSDEELKIIIGESLKEGYIDSIEGEIIKNAVDFSDTLAREIMTPRKDMICLNAQDGY
CCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEECCCCC
EKNIDIILQTNHTRYPYYQDSKDNILGMIHIRDLFENAIKGKEHNLSKLVRNMIIVPESA
CCCCEEEEEECCCCCCCEECCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHEECCCCH
HISEILNTMNRQQVHTALVVDEYGGTSGLLTMEDIIEEIMGDISDEHDLKIEDMRQIDAQ
HHHHHHHHHHHHHHHHEEEEECCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHCCH
TYEFDGKLEISDIEEMLDITFKNTNDHITIGGYVFGLFGRLPMMKDKITDEHCIFEVLEM
HEECCCEEEHHHHHHHHHEEEECCCCEEEEHHHHHHHHCCCCCHHHHCCCHHHHHHHHHC
EGARIKKLKVTYTPKITSTL
CCCEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]