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The map label for this gene is siaT [H]

Identifier: 32267369

GI number: 32267369

Start: 1790213

End: 1791487

Strand: Direct

Name: siaT [H]

Synonym: HH1870

Alternate gene names: 32267369

Gene position: 1790213-1791487 (Clockwise)

Preceding gene: 32267368

Following gene: 32267370

Centisome position: 99.5

GC content: 36.47

Gene sequence:

>1275_bases
ATGAGTGTTGCATATCTAATGGTTGCTTTATTTGGTTTATTGCTTTTAGGTGTTCCTGTTTCGGTTGCTTTAGGCATAAG
CGCAATTAGTGCACTGTATTTTTTTACTTCATACAATATTATTGGTTCAGCTGAAATTATGTTTAATGGCTTAAAACCTG
CTCTTATGGCAATTCCTATGTTTATTCTTGCAGGTTCTCTTATGAGTAAAGGAAGTTCAGCTCAACGTATTATCAATTTT
GCAACCTCTCTTGTAGGGCATTTACCGGGTGGATTACCTATAAGTGCAATTTTAGCTTGTATAATTTTTGCTGCCGTAAG
CGGTAGCTCCCCTGCTACGGTTGTAGCTGTAGGTTCAGTAATGTTTTTAGCCATTGCTAATGCAAAATATCCAAAAAGTT
ATGCCATAGGTGCTATTACATCAGCTGGAAGTCTAGGGATTCTTATTCCTCCTTCAGTTGTAATGATTGTCTATGGTGTA
ACAGCAGAAGTTTCCATTGAAAAACTTTTTATGGCAGGAGTGATTCCGGGGTTAATGATTGGCACTATGATGATGCTTTA
TGCGTATGTAGGTGCAAAACGACTAGGTTTCAAAGCGACAAAACCTGAAAGTTTCAAAGTGCGTTTTCAAAAATTCAGAG
AAGCATTTTGGGCATTGCTTATTGTCTTTGTTATCATTGGAGGTATTTATGGGGGTATATTTACTGCTACAGAAGCAGCA
GGCATTAGTGCAGTATATGCGTTTATTATTTCTGTTTTTGTATATAAAGATATTAAACTCAAGAATCTTCATTCGGTATT
TTTAGATGCAGCTATTACCACAGCTATGATATTTTTTATCATAGGTTTTGCAGTCGTATTTGCACATTTTTTAACCAATG
AGAGAATCCCTCATCTTATAGCTGAATTTCTTATTGCGCAGCAAATGAGTTGGTGGGTATTTCTTATCCTTGTAAATATT
ATGCTCTTTGTTATGGGGCAGTTTATGGAACCTAGCTCTGTGATTATGATAATGACACCTCTCCTTTTGCCCATTGCCTT
AGCTCTTGGTATAGACCCCATACATTTTGGTGTTGTAATGGTTGTAAATATGGAACTAGGTATGCTTACACCACCTGTAG
GTTTAAATCTTTTTGTGGCAAGTTCACTTACTGGGCTTAGCCTTAAAGATGTAACAACTTCGGTGCTTCCTTGGCTTGGA
ATAATGTTGGTGGGTTTATTGCTTATAACTTATATTCCAGATATTTCGCTTTGGTTACCTAATAAACTCAATTAA

Upstream 100 bases:

>100_bases
AAAATCTATGAAGTCTCTTGGATGGAAGCAGACAAAGTAATTAAAAATGCCGAAAATGAAATGATACACGATTCTGTGAT
TAAAGATTAATGGAGTATTA

Downstream 100 bases:

>100_bases
AAGGAGGATTTATGGAGTTTAAAAATGTCAAGCAAATTGAAAAGGCTCAGAACTTTAACCAAAAAGATGGTATAAAGCTT
TTTATTGTACTCATCTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSVAYLMVALFGLLLLGVPVSVALGISAISALYFFTSYNIIGSAEIMFNGLKPALMAIPMFILAGSLMSKGSSAQRIINF
ATSLVGHLPGGLPISAILACIIFAAVSGSSPATVVAVGSVMFLAIANAKYPKSYAIGAITSAGSLGILIPPSVVMIVYGV
TAEVSIEKLFMAGVIPGLMIGTMMMLYAYVGAKRLGFKATKPESFKVRFQKFREAFWALLIVFVIIGGIYGGIFTATEAA
GISAVYAFIISVFVYKDIKLKNLHSVFLDAAITTAMIFFIIGFAVVFAHFLTNERIPHLIAEFLIAQQMSWWVFLILVNI
MLFVMGQFMEPSSVIMIMTPLLLPIALALGIDPIHFGVVMVVNMELGMLTPPVGLNLFVASSLTGLSLKDVTTSVLPWLG
IMLVGLLLITYIPDISLWLPNKLN

Sequences:

>Translated_424_residues
MSVAYLMVALFGLLLLGVPVSVALGISAISALYFFTSYNIIGSAEIMFNGLKPALMAIPMFILAGSLMSKGSSAQRIINF
ATSLVGHLPGGLPISAILACIIFAAVSGSSPATVVAVGSVMFLAIANAKYPKSYAIGAITSAGSLGILIPPSVVMIVYGV
TAEVSIEKLFMAGVIPGLMIGTMMMLYAYVGAKRLGFKATKPESFKVRFQKFREAFWALLIVFVIIGGIYGGIFTATEAA
GISAVYAFIISVFVYKDIKLKNLHSVFLDAAITTAMIFFIIGFAVVFAHFLTNERIPHLIAEFLIAQQMSWWVFLILVNI
MLFVMGQFMEPSSVIMIMTPLLLPIALALGIDPIHFGVVMVVNMELGMLTPPVGLNLFVASSLTGLSLKDVTTSVLPWLG
IMLVGLLLITYIPDISLWLPNKLN
>Mature_423_residues
SVAYLMVALFGLLLLGVPVSVALGISAISALYFFTSYNIIGSAEIMFNGLKPALMAIPMFILAGSLMSKGSSAQRIINFA
TSLVGHLPGGLPISAILACIIFAAVSGSSPATVVAVGSVMFLAIANAKYPKSYAIGAITSAGSLGILIPPSVVMIVYGVT
AEVSIEKLFMAGVIPGLMIGTMMMLYAYVGAKRLGFKATKPESFKVRFQKFREAFWALLIVFVIIGGIYGGIFTATEAAG
ISAVYAFIISVFVYKDIKLKNLHSVFLDAAITTAMIFFIIGFAVVFAHFLTNERIPHLIAEFLIAQQMSWWVFLILVNIM
LFVMGQFMEPSSVIMIMTPLLLPIALALGIDPIHFGVVMVVNMELGMLTPPVGLNLFVASSLTGLSLKDVTTSVLPWLGI
MLVGLLLITYIPDISLWLPNKLN

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=416, Percent_Identity=33.1730769230769, Blast_Score=225, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45389; Mature: 45258

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVAYLMVALFGLLLLGVPVSVALGISAISALYFFTSYNIIGSAEIMFNGLKPALMAIPM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHCCCCHHHHHHHH
FILAGSLMSKGSSAQRIINFATSLVGHLPGGLPISAILACIIFAAVSGSSPATVVAVGSV
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
MFLAIANAKYPKSYAIGAITSAGSLGILIPPSVVMIVYGVTAEVSIEKLFMAGVIPGLMI
HHHHHHCCCCCCCCCCEEEECCCCCEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GTMMMLYAYVGAKRLGFKATKPESFKVRFQKFREAFWALLIVFVIIGGIYGGIFTATEAA
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GISAVYAFIISVFVYKDIKLKNLHSVFLDAAITTAMIFFIIGFAVVFAHFLTNERIPHLI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AEFLIAQQMSWWVFLILVNIMLFVMGQFMEPSSVIMIMTPLLLPIALALGIDPIHFGVVM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
VVNMELGMLTPPVGLNLFVASSLTGLSLKDVTTSVLPWLGIMLVGLLLITYIPDISLWLP
EEEEHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NKLN
CCCC
>Mature Secondary Structure 
SVAYLMVALFGLLLLGVPVSVALGISAISALYFFTSYNIIGSAEIMFNGLKPALMAIPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHCCCCHHHHHHHH
FILAGSLMSKGSSAQRIINFATSLVGHLPGGLPISAILACIIFAAVSGSSPATVVAVGSV
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
MFLAIANAKYPKSYAIGAITSAGSLGILIPPSVVMIVYGVTAEVSIEKLFMAGVIPGLMI
HHHHHHCCCCCCCCCCEEEECCCCCEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GTMMMLYAYVGAKRLGFKATKPESFKVRFQKFREAFWALLIVFVIIGGIYGGIFTATEAA
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GISAVYAFIISVFVYKDIKLKNLHSVFLDAAITTAMIFFIIGFAVVFAHFLTNERIPHLI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AEFLIAQQMSWWVFLILVNIMLFVMGQFMEPSSVIMIMTPLLLPIALALGIDPIHFGVVM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
VVNMELGMLTPPVGLNLFVASSLTGLSLKDVTTSVLPWLGIMLVGLLLITYIPDISLWLP
EEEEHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NKLN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]