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The map label for this gene is yihK

Identifier: 32267271

GI number: 32267271

Start: 1694417

End: 1696096

Strand: Direct

Name: yihK

Synonym: HH1772

Alternate gene names: 32267271

Gene position: 1694417-1696096 (Clockwise)

Preceding gene: 32267270

Following gene: 32267272

Centisome position: 94.18

GC content: 38.63

Gene sequence:

>1680_bases
ATGGATTCTAATGATTTAGAAAGAGAACGAGGTATTACTATTCTTTCAAAAAATACAGCTATCAATTATAAGGGGACAAA
AATAAATATTATTGACACGCCCGGACACGCGGATTTTGGTGGAGAGGTAGAACGGGTGCTTAAAATGGTTGATGGCGTGC
TGCTTCTTGTAGATGCACAAGAAGGTGTTATGCCTCAAACAAAGTTTGTTGTGAAAAAAGCACTTGGTTTTGGAATCCGC
CCCATTGTAGTAGTTAATAAAATTGATAAGCCAGCTGCCCAACCTCATAGAGTGATTGATGAAGTTTTTGATTTATTTGT
AGCAATGGGTGCAAGTGATGAACAACTAGATTTTCCTGTAGTTTATGCTGCTGCACGAGATGGTTATGCAATCAAAGAGT
TAGAAGATGAAAAGAAAAATCTTGAACCTCTTTTTGAGGCAATTTTAGAATATGTCCCACTGCCAAGTGGTGCAAAAGAG
AATCCTTTGCAAATGCAAGTATTTACGCTTGATTATGATAATTATGTAGGAAAAATCGGCATTGCTCGTGTATTTAATGG
TTGTATAAAAAAAGGTGAGAATGTAATGCTTGCTAAAAGTGATGGCGAGAAAGAAACTGGGCGCATTAGTAAGCTTATTG
GCTTTTTAGGCTTAGCACGCACAGAGATAGAATCTGCTGAAGCCGGTGATATTGTTGCTATTGCCGGTTTTAATGCCGTT
GATGTTGGAGATTCTATTGTATGTCCTACTAATCCTATGCCGCTTGACCCTATGCACCTTGAAGAACCTACAATGAGTGT
GTATTTTGCAGTTAATGATAGCCCTTTAGCAGGGTTGGAGGGCAAACACGTAACGGCAAATAAAATTAAAGATAGGCTCT
TAAAAGAAATGCAAACTAACATTGCTATGCGTTGTGAAGAAATGGGCGAGGGAAAATTCAAAGTGAGTGGGCGAGGGGAG
TTACAAATTACCATTTTGGCTGAAAATTTGCGCCGAGAAGGCTTTGAATTTAGTATTTCACGTCCTGAAGTAATTATCAA
AGAAGAGAATGGTGTGAAATGCGAGCCATTTGAGCATTTAGTCATTGATACGCCGCAAGATTTTAGCGGGGCGATTATTG
AAAAGCTTGGCAAGAGAAAGGCAGAGATGAAAGCTATGAATCCTATGAGTGATGGCTATACAAGATTAGAGTTTGAGATT
CCAGCGCGTGGGCTTATCGGCTATCGCAGTGAGTTTTTGACAGATACGAAAGGTGAGGGCATTATGAATCATAGTTTTTT
AGAGTTTCGTCCCTTTAGTGGTAGTGTAGAATCTCGTAAAAACGGCGCACTCATTAGTATGGAAAATGGAGATGCGACAG
GTTTTTCACTTTTTAATATCCAAGAGCGAGGAATACTCTTTATAGCACCACAAACTAAAGTATATGTAGGAATGGTCATT
GGTGAGCATAGCAGAGATAATGATTTAGATGTTAATCCTATTAAGGCAAAACACTTAACTAATATGCGTAGTAGTGGGGC
TGATGAAGCGATTAAACTTGTGCCACCAAGGGATTTAACACTAGAGAGGGCATTAGAATGGATAGAAGATGATGAAATAC
TTGAAGTAACTCCTCAAACTATTAGAATCCGTAAAAAGATTCTAGAGCCAAATATGCGTAAAAGAGCAAAAGCAAAATAA

Upstream 100 bases:

>100_bases
TGTTATTGCTCACGTTGATCACGGAAAAACTACACTTGTAGATGGGCTACTTACTCAATCCGGTACTTTTGGCGAGAGGG
AACAAATTGATGAGCGTGTT

Downstream 100 bases:

>100_bases
GTTGGTTTATTAAGGGGTGTTTGCCACCCTTTTATTAAGCCAATGGCTTAAAATTAAATAAAGGAAAAACAATGAATCCT
TTTTTAGAATCAATTTATTT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MDSNDLERERGITILSKNTAINYKGTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALGFGIR
PIVVVNKIDKPAAQPHRVIDEVFDLFVAMGASDEQLDFPVVYAAARDGYAIKELEDEKKNLEPLFEAILEYVPLPSGAKE
NPLQMQVFTLDYDNYVGKIGIARVFNGCIKKGENVMLAKSDGEKETGRISKLIGFLGLARTEIESAEAGDIVAIAGFNAV
DVGDSIVCPTNPMPLDPMHLEEPTMSVYFAVNDSPLAGLEGKHVTANKIKDRLLKEMQTNIAMRCEEMGEGKFKVSGRGE
LQITILAENLRREGFEFSISRPEVIIKEENGVKCEPFEHLVIDTPQDFSGAIIEKLGKRKAEMKAMNPMSDGYTRLEFEI
PARGLIGYRSEFLTDTKGEGIMNHSFLEFRPFSGSVESRKNGALISMENGDATGFSLFNIQERGILFIAPQTKVYVGMVI
GEHSRDNDLDVNPIKAKHLTNMRSSGADEAIKLVPPRDLTLERALEWIEDDEILEVTPQTIRIRKKILEPNMRKRAKAK

Sequences:

>Translated_559_residues
MDSNDLERERGITILSKNTAINYKGTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALGFGIR
PIVVVNKIDKPAAQPHRVIDEVFDLFVAMGASDEQLDFPVVYAAARDGYAIKELEDEKKNLEPLFEAILEYVPLPSGAKE
NPLQMQVFTLDYDNYVGKIGIARVFNGCIKKGENVMLAKSDGEKETGRISKLIGFLGLARTEIESAEAGDIVAIAGFNAV
DVGDSIVCPTNPMPLDPMHLEEPTMSVYFAVNDSPLAGLEGKHVTANKIKDRLLKEMQTNIAMRCEEMGEGKFKVSGRGE
LQITILAENLRREGFEFSISRPEVIIKEENGVKCEPFEHLVIDTPQDFSGAIIEKLGKRKAEMKAMNPMSDGYTRLEFEI
PARGLIGYRSEFLTDTKGEGIMNHSFLEFRPFSGSVESRKNGALISMENGDATGFSLFNIQERGILFIAPQTKVYVGMVI
GEHSRDNDLDVNPIKAKHLTNMRSSGADEAIKLVPPRDLTLERALEWIEDDEILEVTPQTIRIRKKILEPNMRKRAKAK
>Mature_559_residues
MDSNDLERERGITILSKNTAINYKGTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALGFGIR
PIVVVNKIDKPAAQPHRVIDEVFDLFVAMGASDEQLDFPVVYAAARDGYAIKELEDEKKNLEPLFEAILEYVPLPSGAKE
NPLQMQVFTLDYDNYVGKIGIARVFNGCIKKGENVMLAKSDGEKETGRISKLIGFLGLARTEIESAEAGDIVAIAGFNAV
DVGDSIVCPTNPMPLDPMHLEEPTMSVYFAVNDSPLAGLEGKHVTANKIKDRLLKEMQTNIAMRCEEMGEGKFKVSGRGE
LQITILAENLRREGFEFSISRPEVIIKEENGVKCEPFEHLVIDTPQDFSGAIIEKLGKRKAEMKAMNPMSDGYTRLEFEI
PARGLIGYRSEFLTDTKGEGIMNHSFLEFRPFSGSVESRKNGALISMENGDATGFSLFNIQERGILFIAPQTKVYVGMVI
GEHSRDNDLDVNPIKAKHLTNMRSSGADEAIKLVPPRDLTLERALEWIEDDEILEVTPQTIRIRKKILEPNMRKRAKAK

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=268, Percent_Identity=33.2089552238806, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI94966754, Length=94, Percent_Identity=44.6808510638298, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI18390331, Length=102, Percent_Identity=43.1372549019608, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI25306287, Length=87, Percent_Identity=48.2758620689655, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI19923640, Length=87, Percent_Identity=48.2758620689655, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI25306283, Length=87, Percent_Identity=48.2758620689655, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI94966752, Length=63, Percent_Identity=50.7936507936508, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI34147630, Length=235, Percent_Identity=27.2340425531915, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4503483, Length=105, Percent_Identity=36.1904761904762, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI217272892, Length=126, Percent_Identity=36.5079365079365, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI217272894, Length=126, Percent_Identity=36.5079365079365, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994988, Length=560, Percent_Identity=52.1428571428571, Blast_Score=599, Evalue=1e-172,
Organism=Escherichia coli, GI1788922, Length=258, Percent_Identity=34.4961240310078, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1789738, Length=109, Percent_Identity=40.3669724770642, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790835, Length=101, Percent_Identity=31.6831683168317, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17557151, Length=258, Percent_Identity=29.8449612403101, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17556745, Length=98, Percent_Identity=43.8775510204082, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17533571, Length=100, Percent_Identity=47, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71988811, Length=90, Percent_Identity=42.2222222222222, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71988819, Length=90, Percent_Identity=42.2222222222222, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17506493, Length=84, Percent_Identity=39.2857142857143, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=444, Percent_Identity=24.7747747747748, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6323098, Length=106, Percent_Identity=42.4528301886792, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324707, Length=107, Percent_Identity=42.0560747663551, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320593, Length=107, Percent_Identity=42.0560747663551, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322359, Length=103, Percent_Identity=38.8349514563107, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324761, Length=227, Percent_Identity=28.6343612334802, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI78706572, Length=451, Percent_Identity=25.4988913525499, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24582462, Length=102, Percent_Identity=45.0980392156863, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24585711, Length=127, Percent_Identity=34.6456692913386, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24585713, Length=127, Percent_Identity=34.6456692913386, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24585709, Length=127, Percent_Identity=34.6456692913386, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574573, Length=99, Percent_Identity=35.3535353535354, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 62074; Mature: 62074

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSNDLERERGITILSKNTAINYKGTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQ
CCCCCCCHHCCEEEEECCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECC
EGVMPQTKFVVKKALGFGIRPIVVVNKIDKPAAQPHRVIDEVFDLFVAMGASDEQLDFPV
CCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCE
VYAAARDGYAIKELEDEKKNLEPLFEAILEYVPLPSGAKENPLQMQVFTLDYDNYVGKIG
EEEECCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCHHHHH
IARVFNGCIKKGENVMLAKSDGEKETGRISKLIGFLGLARTEIESAEAGDIVAIAGFNAV
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEE
DVGDSIVCPTNPMPLDPMHLEEPTMSVYFAVNDSPLAGLEGKHVTANKIKDRLLKEMQTN
CCCCEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHH
IAMRCEEMGEGKFKVSGRGELQITILAENLRREGFEFSISRPEVIIKEENGVKCEPFEHL
HHHHHHHCCCCEEEECCCCEEEEEEEEEHHHCCCCEEECCCCEEEEECCCCCCCCCCCEE
VIDTPQDFSGAIIEKLGKRKAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLTDTKGEG
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCC
IMNHSFLEFRPFSGSVESRKNGALISMENGDATGFSLFNIQERGILFIAPQTKVYVGMVI
CCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCEEEEEEECCCEEEECCCCEEEEEEEE
GEHSRDNDLDVNPIKAKHLTNMRSSGADEAIKLVPPRDLTLERALEWIEDDEILEVTPQT
ECCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCCCEEEECHHH
IRIRKKILEPNMRKRAKAK
HHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure
MDSNDLERERGITILSKNTAINYKGTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQ
CCCCCCCHHCCEEEEECCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECC
EGVMPQTKFVVKKALGFGIRPIVVVNKIDKPAAQPHRVIDEVFDLFVAMGASDEQLDFPV
CCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCE
VYAAARDGYAIKELEDEKKNLEPLFEAILEYVPLPSGAKENPLQMQVFTLDYDNYVGKIG
EEEECCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCHHHHH
IARVFNGCIKKGENVMLAKSDGEKETGRISKLIGFLGLARTEIESAEAGDIVAIAGFNAV
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEE
DVGDSIVCPTNPMPLDPMHLEEPTMSVYFAVNDSPLAGLEGKHVTANKIKDRLLKEMQTN
CCCCEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHH
IAMRCEEMGEGKFKVSGRGELQITILAENLRREGFEFSISRPEVIIKEENGVKCEPFEHL
HHHHHHHCCCCEEEECCCCEEEEEEEEEHHHCCCCEEECCCCEEEEECCCCCCCCCCCEE
VIDTPQDFSGAIIEKLGKRKAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLTDTKGEG
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCC
IMNHSFLEFRPFSGSVESRKNGALISMENGDATGFSLFNIQERGILFIAPQTKVYVGMVI
CCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCEEEEEEECCCEEEECCCCEEEEEEEE
GEHSRDNDLDVNPIKAKHLTNMRSSGADEAIKLVPPRDLTLERALEWIEDDEILEVTPQT
ECCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCCCEEEECHHH
IRIRKKILEPNMRKRAKAK
HHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]