Click here to switch to the map view.

The map label for this gene is lnt

Identifier: 32267127

GI number: 32267127

Start: 1551027

End: 1552229

Strand: Direct

Name: lnt

Synonym: HH1628

Alternate gene names: 32267127

Gene position: 1551027-1552229 (Clockwise)

Preceding gene: 32267126

Following gene: 32267128

Centisome position: 86.21

GC content: 34.16

Gene sequence:

>1203_bases
GTGTTACCTTTTTATGCGCAGTGGGTTTTGGAAAGTTATGATAAAGCAATATCACCATTACTTGTTTCATTACTTGGTTT
ATTCAGTATTGCAAGTGTGCTTTTTGTTCCTAAAAATCGTCGCTTTGGCGTTGGATTCTTTATTGGAATGCTATGGTTTT
ATTGGATAAGTTTAGGACTTAGATATTTTGATATGAGCTTTCTTATTCCTTTAGTTGTAATAGCTTGTGGCATTTTTATG
GGTTTTGTATTTTATATTGGTCTATGGTGTGAATGTTTGATTGTGCGATTTGCGTTTTTATTACTTTTAAGTTATCTTAC
ACCTTTTGGCTTTGATTGGATTGTGCCAGAGAGTGTATTTGCATATAGCTATATTGGTGTGGATAAATTAAGCTTTGCAC
TCTCAATTCTTGCTCTATGGATTTTATTTAAGTATAAAACTTGGTGGAAGTTAGGAGGAGTGATTTGCCTTGTTTTTGCA
CTTGATTTTGGACTTAAGGATTCAAAAATACAGAATCTACCCCCACTTAAAATTAAACTTGCTCAAAGTGCTGTGAGTCA
GGATTTTGATTATCGTATGAGAGAAGCAAAAAGCATATTTAGCGAACATATAAGTGATATACAAAAGGCAATTAATGAAG
AATATGATGTGATAATTCTACCCGAGAGTGCATTTTATGTGCCTTTAGATTCTCAATATTTTCCATATTTTGACTCGCTT
TTAGAGATGAGCCATAAAATTGTTATTATTGTGGGGGCATTACGTGAAGAGATACACACAGATGGAAGAGCGTCTTATTT
CAATAGCACCTATAAATTTGATAAAGGCAAAGTTTCTTTCTACGATAAAGTCCATCTTGTGCCTTTTGGTGAGACTCTCC
CCTCTTTTTTACTGCCACTTGTAAATACATTTTTTCAAGGCATTGGCGGATTTAGTGCTGGGAAAGATTTTGGATATTTT
GATATTGCAGAAATAAAATTTAAAAATGCTATTTGTTATGAGGGAAGTAATCGTGGATTCTATGCGGATTATCCACAATA
TGTGATTGTAACAAGCAATAATGCGTGGTTTGTGCCAAGCATTGAGCCTATATTACAAAAAAATTTGATGAAGTATTATG
CTCGGCTCTATGGCAGTGTAATTTTCCACGCAACAAACCTTTCTCCCGCTGCTATAATTACACCTTTTGTTTCTTCTAGG
TGA

Upstream 100 bases:

>100_bases
TATTTCTATACCTTATACGCATTTTTCTTTTTATAAACCACAGACTTACAAACCAACAATTCTATGGCATTTTATATCTT
TTATATTTGCATTTTTATAT

Downstream 100 bases:

>100_bases
ATGCCGTAGAAAATCACTTAAGAGAAAATATAAAAAACCGATTTTAAGCCGATATTAGTTTATTATGGTATCATAGGCAG
TTTAAACCATAAAAGGAGTT

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MLPFYAQWVLESYDKAISPLLVSLLGLFSIASVLFVPKNRRFGVGFFIGMLWFYWISLGLRYFDMSFLIPLVVIACGIFM
GFVFYIGLWCECLIVRFAFLLLLSYLTPFGFDWIVPESVFAYSYIGVDKLSFALSILALWILFKYKTWWKLGGVICLVFA
LDFGLKDSKIQNLPPLKIKLAQSAVSQDFDYRMREAKSIFSEHISDIQKAINEEYDVIILPESAFYVPLDSQYFPYFDSL
LEMSHKIVIIVGALREEIHTDGRASYFNSTYKFDKGKVSFYDKVHLVPFGETLPSFLLPLVNTFFQGIGGFSAGKDFGYF
DIAEIKFKNAICYEGSNRGFYADYPQYVIVTSNNAWFVPSIEPILQKNLMKYYARLYGSVIFHATNLSPAAIITPFVSSR

Sequences:

>Translated_400_residues
MLPFYAQWVLESYDKAISPLLVSLLGLFSIASVLFVPKNRRFGVGFFIGMLWFYWISLGLRYFDMSFLIPLVVIACGIFM
GFVFYIGLWCECLIVRFAFLLLLSYLTPFGFDWIVPESVFAYSYIGVDKLSFALSILALWILFKYKTWWKLGGVICLVFA
LDFGLKDSKIQNLPPLKIKLAQSAVSQDFDYRMREAKSIFSEHISDIQKAINEEYDVIILPESAFYVPLDSQYFPYFDSL
LEMSHKIVIIVGALREEIHTDGRASYFNSTYKFDKGKVSFYDKVHLVPFGETLPSFLLPLVNTFFQGIGGFSAGKDFGYF
DIAEIKFKNAICYEGSNRGFYADYPQYVIVTSNNAWFVPSIEPILQKNLMKYYARLYGSVIFHATNLSPAAIITPFVSSR
>Mature_400_residues
MLPFYAQWVLESYDKAISPLLVSLLGLFSIASVLFVPKNRRFGVGFFIGMLWFYWISLGLRYFDMSFLIPLVVIACGIFM
GFVFYIGLWCECLIVRFAFLLLLSYLTPFGFDWIVPESVFAYSYIGVDKLSFALSILALWILFKYKTWWKLGGVICLVFA
LDFGLKDSKIQNLPPLKIKLAQSAVSQDFDYRMREAKSIFSEHISDIQKAINEEYDVIILPESAFYVPLDSQYFPYFDSL
LEMSHKIVIIVGALREEIHTDGRASYFNSTYKFDKGKVSFYDKVHLVPFGETLPSFLLPLVNTFFQGIGGFSAGKDFGYF
DIAEIKFKNAICYEGSNRGFYADYPQYVIVTSNNAWFVPSIEPILQKNLMKYYARLYGSVIFHATNLSPAAIITPFVSSR

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily

Homologues:

Organism=Escherichia coli, GI1786878, Length=356, Percent_Identity=25.8426966292135, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_HELHP (Q7VFP7)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_861159.1
- ProteinModelPortal:   Q7VFP7
- GeneID:   1492175
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH1628
- NMPDR:   fig|235279.1.peg.1628
- HOGENOM:   HBG393025
- OMA:   AICYEAT
- ProtClustDB:   PRK12291
- BioCyc:   HHEP235279:HH_1628-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 45856; Mature: 45856

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfe36618)-; HASH(0x1021ec4c)-; HASH(0x100161fc)-; HASH(0xfaf5f34)-; HASH(0xf4f9834)-; HASH(0xea54238)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPFYAQWVLESYDKAISPLLVSLLGLFSIASVLFVPKNRRFGVGFFIGMLWFYWISLGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
RYFDMSFLIPLVVIACGIFMGFVFYIGLWCECLIVRFAFLLLLSYLTPFGFDWIVPESVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AYSYIGVDKLSFALSILALWILFKYKTWWKLGGVICLVFALDFGLKDSKIQNLPPLKIKL
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
AQSAVSQDFDYRMREAKSIFSEHISDIQKAINEEYDVIILPESAFYVPLDSQYFPYFDSL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCHHHHHH
LEMSHKIVIIVGALREEIHTDGRASYFNSTYKFDKGKVSFYDKVHLVPFGETLPSFLLPL
HHCCCCEEEEEHHHHHHHCCCCCHHHCCCCEEECCCCEEEEEEEEEEECCHHHHHHHHHH
VNTFFQGIGGFSAGKDFGYFDIAEIKFKNAICYEGSNRGFYADYPQYVIVTSNNAWFVPS
HHHHHHHCCCCCCCCCCCCEEHHHEEECCEEEEECCCCCEEECCCCEEEEECCCEEECCC
IEPILQKNLMKYYARLYGSVIFHATNLSPAAIITPFVSSR
CHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHCCCHHCCH
>Mature Secondary Structure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CHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHCCCHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12810954