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The map label for this gene is guaA

Identifier: 32266943

GI number: 32266943

Start: 1390108

End: 1394235

Strand: Direct

Name: guaA

Synonym: HH1444

Alternate gene names: 32266943

Gene position: 1390108-1394235 (Clockwise)

Preceding gene: 32266939

Following gene: 32266944

Centisome position: 77.26

GC content: 42.97

Gene sequence:

>4128_bases
ATGCAAGAAAATAATGTCCAAATTTTAGTGCTAGATTTTGGCTCTCAATACACACAGCTTATCGCAAGGCGACTACGTGA
ATATGGCGTTTATACCGAGATTGTCCCTTACTTTGAAAAGCTAGATTCTATTAAGAGCAAAAATCCTAAGGGCATTATCC
TAAGTGGAGGACCTGCAAGCGTGTATGAAAAAGACGCTTATAAGCCTGATAGTGCGATTTTCACGCTTGGGATTCCCATT
CTTGGCATCTGCTATGGTATGCAGCTCATCGCCCAACATTTTGGCGGACGCGTTATCAAGGCGGACGCGCAAGAATTTGG
CAAGGCGGTGCTAGAGATTATGGAATCTTCTCAAGATTCTAAAGATTCTTCTTGTTTCGCATTTCAAGGTGCTTCTCAAG
GCATACAAGCACCAATGACGCTCTCTTTTGATATTTTTTCTCATCACAAGTTTCCTCAAATGCTCACAGCCCTGCTTGAT
TTATGGGAAGATTCTGTGCAAGCAAGCCATATTTTTTTAACTAAGCAACACATTGCAGAGATTAGGCTAGAAGTCAAAGC
GGCATTGCAAAGCTCCCAAAACATCATCACTGCGACAGATAAAAAGGATTTTTTGGGCTTTATCGGTGTGGAAAAGAATA
AGATTGAAATGCTTTTTGTCGCATCGAGTGTCTTTAGAAAAGGTATAGGCAAAGCACTACTCAAAGAGGCGTTGGAGCGA
TATTTGAAAGACTATCCTTACATTTTAGTAGATTGCAATGAACAAAACACGCAAGGTTTGGCATTTTATAAGTCTTTGGG
CTTTGAAAAAGTAGGAATGAGTGAAAAAGATTCCGCAGGGAGAGACTTCCCCATCGTGCATTTAAAGGTGAGCAAAGCGA
TATTAAAAAAAGCACTTGAAAGAGGAACTAGCGATTCTGTGGCAAATGCTTTTGTGTGCGAGAGCGAGCGCGTCTTTTTG
CGCCCTTATACACAGGCAGATTTTGCGGCATTGCATAAAATTGTGAGTGATAAGGAAACAATGTATGCGTGGGGGCAGGG
CTTTAGCAAAAAGCAGAGCCAAGAATGGCTGGATAAGCAATTAGCGCATTATCAACAATATGGCTTTGGAATCTGGGCGA
TTATAGAGAAGCAAAGCGGCGCAATTATCGGCAATGCGGGGCTAAATCATACGGAGATAAGTCTAAAGGGCAAAACTCAA
AAAATTGTAGAAATCGGCTATCTTTTGCACCGCGATTTTTGGGGCAAAGGCTATGGAAGCGAAGTGGCTAGAATGTGCGT
AAAATATGGCTTTGAAACTTTGGGATTGGAGGAAGTGTATTGTCTCATCAAAGAGGATAATACCGCTTCAATCAAGGTAG
CAAAAAGGCTTGAAATGCAAAAAGTGGGGGAATATCCTAAACCTTATAAGGGCAAAAAAATCAGTCATCTTGTCTTTAGG
CTTGAAAAAAAAGTATGGCAAGAATCCAAAAATAACGCCACGCAAGGTTTTAAATCTTGCTCACTTTTTAAAGGCATAAA
GCAAGATTCTATCGTGTGGATGAGCCACGCGGACAAGGTAGAATCTATCCCGCAAGGATTTAGAGAGCTTGCAAAGTCTG
GAAATACTCATTATTGCGCGATTGCGGATTCTAAACGCAAGATTTATGCCCTGCAGTTTCACCCTGAAGTTGTGCATAGT
GAATGTGGTGGGCAAATGTTGCAAAACTTTGCAGTAGGGATTTGCGGTGCAAATACTTGCTGGAATATGCGTCATTTCGC
GCAAAATGAGATTGAAAAATTGCGCCGTATCGTCTATGGAGGCAAGGCACATTGTGAAAATCCTATGAGTTTTATGCAGA
TTCAAGAAGCCTTTAAGCACATTGGCAAAGCACAAACCATACAAAGACTTGTTGAAATCTGGGAGGAAGGTGCAAGGGCT
ACACACAAAGATTTAAGCGAAAATGAAATTGCGGGTATGAGAGAGGAAATACGGGAGGCTATATTAAAATCTAAAAATTT
ACTTATAGCGCAAAAAAATGAAGAATGGTTAGGTTTTATTGAGATAGAAAAAAATGAAATTGCAATGCTTTTTGTCGTTC
CAAAAGCCTTTAGAAAGGGTGTGGGCAAGGCACTGCTCAAAGAGGCATTTATGCGGTATTTAGGTGCATTTGAAGTGATA
AAGGTTAATAGTCTTGAGTGGGCTTTAGGATTCTATCAGGCTTTGGGGTTTGCAAAAACAGGAAAAAAGCCTATCCCTGC
GGGGAGTGCTGGTGCATTTTCACCCGAACTTATCCCTCTAAGCATTGCGCGTGAGAGTTTGCAAAAGTCTTTGGGGCTTG
AGGCGCAAGATTCAAATGAGGGTGTGCGTGAAAAGGTGCGTTGCGCTTGGGCTACCGATAAGGACGAGGCGGCGCGTAAG
CTCTATGAGGACTACCACGACACAGAGTGGGGCGAACCACTGCACGAGGATAAAAAGCTCTTTGAACATCTTGTGCTAGA
GGGCTTTCAAGCGGGACTTTCTTGGATTACGATTCTTAAAAAACGCGAGGCTTTTAGGGTGGCATTTGATGACTTTGACC
CTCACATTGTAGCCAACTATGATGAGGACAAAATCAAAGAGCTAATGCGAAATGAGGGGATTATTAGGAATCGTGCCAAA
ATAGAAGCAGCGATTATCAATGCTAAGGCATTTATGGCGGTGCAAAGGGAGTTTGGGAGCTTTGATAAATATATTTGGGG
CTTTGTGGGAGGTAAGCCGATTATCAATGCCTTTGAAAGCATTGCGGATTTACCCGCTTCCACGCCGCTATCGGATAAAA
TCGCTAAGGATTTGAAAAAGCGCGGGTTTAAGTTTGTCGGCACTACGACTATGTATGCGATGATGCAGAGTATTGGAATG
GTGAATGACCATCTTACCTCGTGCTTTAAGTGCAATTCATCTTTGGGTATGCAATGCGATAAGATTTTGGATTTTTCGCA
GGGCACGAACACTAAGTCCGCTAACCTTACAAAAAATCCAAAAAACTTACACAGCCACACCGCAAATACTAGAATTGTGG
ATTCTCAACATACAGAATCTAGCGACATTAAAGGGCAAAGTCATTTAGAATCTAGTGCAGATTCAGGTTCGGCAGTATCT
TTGAGGGATTTTAAGAGTTGTGAAGGTGCGACACGAGGGAGTTACCTTGAGGGTAATGACAGAAGTGGAGTAGCAAACTC
TCTTAAAATCACCAAAGAGACAACGAGTAAAGTGTTGTGTGCGGTGAGTGGTGGGGTAGATAGCTCCGTTGTCGCTGCAC
TTTTATATCGCGCCATTGGGGAGAATCTTATTCCAGTGTTTGTTGATACCGGACTTTTGCGCAAAGGCGAGAGAGAGGCA
GTGGAGAAAATATTTAAAGAAAATCTCAAAGTGCCCCTGATTACTGCGGACGCAAGTGAGTTATTTTTAAGCCGCCTTAA
GGGTGTGCTTGACCCCGAGATTAAGCGTAAAATTATCGGCGAGACTTTCATTGAAGTGTTTGAAAAAGAGGCGAAAAAGC
ATAATACAAAAGGTGAGATAAAGTTCCTCGCGCAAGGCACACTCTACCCTGATGTGATAGAATCTGTGAGTGTGAAGGGT
CCCTCTAAGACGATAAAGTCTCATCATAATGTCGGTGGGTTACCTGAATGGATGAAGTTTGAGCTGATTGAGCCATTACG
AGAGCTATTTAAGGACGAAGTAAGGGCATTAGGGCGAGAGCTTGGAATGCCTGAATCTATGCTAATGCGCCACCCATTCC
CCGGACCCGGGCTAGCCATTCGCATTATGGGAGAGGTGAATAAGGCAGATTTGGATTTGCTGCGTGAGGCGGATTCTATC
TTTATAGACGAGCTACACAAACAAAGCTATTATGATAAGGTATGGCAGGCGTTTTGTGTGCTGCTCAATGTGCGGAGTGT
GGGTGTAATGGGCGATAATCGCACTTATGATAATACGATTTGTGTAAGAGCGGTGGAAGCGATTGACGGAATGACCGCAA
CTTTTGCGCATTTGCCTCACGATTTTTTAGAGGGCGTAAGTAATAGAATCATCAACGAAGTAGAGGGCATTAACCGCGTG
GTGTATGATATCACAAGCAAACCGCCAGGGACGATTGAGTGGGAGTGA

Upstream 100 bases:

>100_bases
TCTCAATCACAAAGCTTGAATAAAAGCACTTATAAGCAACTTTTAGCTAAGATTGCGCCGAAAATTAACAAATGTAAATC
TACTTTATCAAGGATTCTTT

Downstream 100 bases:

>100_bases
GGGGAAGTGTTATGAATTATTTTTTAGTTCAAACCATAGAACTTGCAAATCAAAAGGATTATTTTGAGAGTAGCTTTTTA
GAGTATATCCTATAAGTCCA

Product: guanosine monophosphate synthetase GuaA

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase

Number of amino acids: Translated: 1375; Mature: 1375

Protein sequence:

>1375_residues
MQENNVQILVLDFGSQYTQLIARRLREYGVYTEIVPYFEKLDSIKSKNPKGIILSGGPASVYEKDAYKPDSAIFTLGIPI
LGICYGMQLIAQHFGGRVIKADAQEFGKAVLEIMESSQDSKDSSCFAFQGASQGIQAPMTLSFDIFSHHKFPQMLTALLD
LWEDSVQASHIFLTKQHIAEIRLEVKAALQSSQNIITATDKKDFLGFIGVEKNKIEMLFVASSVFRKGIGKALLKEALER
YLKDYPYILVDCNEQNTQGLAFYKSLGFEKVGMSEKDSAGRDFPIVHLKVSKAILKKALERGTSDSVANAFVCESERVFL
RPYTQADFAALHKIVSDKETMYAWGQGFSKKQSQEWLDKQLAHYQQYGFGIWAIIEKQSGAIIGNAGLNHTEISLKGKTQ
KIVEIGYLLHRDFWGKGYGSEVARMCVKYGFETLGLEEVYCLIKEDNTASIKVAKRLEMQKVGEYPKPYKGKKISHLVFR
LEKKVWQESKNNATQGFKSCSLFKGIKQDSIVWMSHADKVESIPQGFRELAKSGNTHYCAIADSKRKIYALQFHPEVVHS
ECGGQMLQNFAVGICGANTCWNMRHFAQNEIEKLRRIVYGGKAHCENPMSFMQIQEAFKHIGKAQTIQRLVEIWEEGARA
THKDLSENEIAGMREEIREAILKSKNLLIAQKNEEWLGFIEIEKNEIAMLFVVPKAFRKGVGKALLKEAFMRYLGAFEVI
KVNSLEWALGFYQALGFAKTGKKPIPAGSAGAFSPELIPLSIARESLQKSLGLEAQDSNEGVREKVRCAWATDKDEAARK
LYEDYHDTEWGEPLHEDKKLFEHLVLEGFQAGLSWITILKKREAFRVAFDDFDPHIVANYDEDKIKELMRNEGIIRNRAK
IEAAIINAKAFMAVQREFGSFDKYIWGFVGGKPIINAFESIADLPASTPLSDKIAKDLKKRGFKFVGTTTMYAMMQSIGM
VNDHLTSCFKCNSSLGMQCDKILDFSQGTNTKSANLTKNPKNLHSHTANTRIVDSQHTESSDIKGQSHLESSADSGSAVS
LRDFKSCEGATRGSYLEGNDRSGVANSLKITKETTSKVLCAVSGGVDSSVVAALLYRAIGENLIPVFVDTGLLRKGEREA
VEKIFKENLKVPLITADASELFLSRLKGVLDPEIKRKIIGETFIEVFEKEAKKHNTKGEIKFLAQGTLYPDVIESVSVKG
PSKTIKSHHNVGGLPEWMKFELIEPLRELFKDEVRALGRELGMPESMLMRHPFPGPGLAIRIMGEVNKADLDLLREADSI
FIDELHKQSYYDKVWQAFCVLLNVRSVGVMGDNRTYDNTICVRAVEAIDGMTATFAHLPHDFLEGVSNRIINEVEGINRV
VYDITSKPPGTIEWE

Sequences:

>Translated_1375_residues
MQENNVQILVLDFGSQYTQLIARRLREYGVYTEIVPYFEKLDSIKSKNPKGIILSGGPASVYEKDAYKPDSAIFTLGIPI
LGICYGMQLIAQHFGGRVIKADAQEFGKAVLEIMESSQDSKDSSCFAFQGASQGIQAPMTLSFDIFSHHKFPQMLTALLD
LWEDSVQASHIFLTKQHIAEIRLEVKAALQSSQNIITATDKKDFLGFIGVEKNKIEMLFVASSVFRKGIGKALLKEALER
YLKDYPYILVDCNEQNTQGLAFYKSLGFEKVGMSEKDSAGRDFPIVHLKVSKAILKKALERGTSDSVANAFVCESERVFL
RPYTQADFAALHKIVSDKETMYAWGQGFSKKQSQEWLDKQLAHYQQYGFGIWAIIEKQSGAIIGNAGLNHTEISLKGKTQ
KIVEIGYLLHRDFWGKGYGSEVARMCVKYGFETLGLEEVYCLIKEDNTASIKVAKRLEMQKVGEYPKPYKGKKISHLVFR
LEKKVWQESKNNATQGFKSCSLFKGIKQDSIVWMSHADKVESIPQGFRELAKSGNTHYCAIADSKRKIYALQFHPEVVHS
ECGGQMLQNFAVGICGANTCWNMRHFAQNEIEKLRRIVYGGKAHCENPMSFMQIQEAFKHIGKAQTIQRLVEIWEEGARA
THKDLSENEIAGMREEIREAILKSKNLLIAQKNEEWLGFIEIEKNEIAMLFVVPKAFRKGVGKALLKEAFMRYLGAFEVI
KVNSLEWALGFYQALGFAKTGKKPIPAGSAGAFSPELIPLSIARESLQKSLGLEAQDSNEGVREKVRCAWATDKDEAARK
LYEDYHDTEWGEPLHEDKKLFEHLVLEGFQAGLSWITILKKREAFRVAFDDFDPHIVANYDEDKIKELMRNEGIIRNRAK
IEAAIINAKAFMAVQREFGSFDKYIWGFVGGKPIINAFESIADLPASTPLSDKIAKDLKKRGFKFVGTTTMYAMMQSIGM
VNDHLTSCFKCNSSLGMQCDKILDFSQGTNTKSANLTKNPKNLHSHTANTRIVDSQHTESSDIKGQSHLESSADSGSAVS
LRDFKSCEGATRGSYLEGNDRSGVANSLKITKETTSKVLCAVSGGVDSSVVAALLYRAIGENLIPVFVDTGLLRKGEREA
VEKIFKENLKVPLITADASELFLSRLKGVLDPEIKRKIIGETFIEVFEKEAKKHNTKGEIKFLAQGTLYPDVIESVSVKG
PSKTIKSHHNVGGLPEWMKFELIEPLRELFKDEVRALGRELGMPESMLMRHPFPGPGLAIRIMGEVNKADLDLLREADSI
FIDELHKQSYYDKVWQAFCVLLNVRSVGVMGDNRTYDNTICVRAVEAIDGMTATFAHLPHDFLEGVSNRIINEVEGINRV
VYDITSKPPGTIEWE
>Mature_1375_residues
MQENNVQILVLDFGSQYTQLIARRLREYGVYTEIVPYFEKLDSIKSKNPKGIILSGGPASVYEKDAYKPDSAIFTLGIPI
LGICYGMQLIAQHFGGRVIKADAQEFGKAVLEIMESSQDSKDSSCFAFQGASQGIQAPMTLSFDIFSHHKFPQMLTALLD
LWEDSVQASHIFLTKQHIAEIRLEVKAALQSSQNIITATDKKDFLGFIGVEKNKIEMLFVASSVFRKGIGKALLKEALER
YLKDYPYILVDCNEQNTQGLAFYKSLGFEKVGMSEKDSAGRDFPIVHLKVSKAILKKALERGTSDSVANAFVCESERVFL
RPYTQADFAALHKIVSDKETMYAWGQGFSKKQSQEWLDKQLAHYQQYGFGIWAIIEKQSGAIIGNAGLNHTEISLKGKTQ
KIVEIGYLLHRDFWGKGYGSEVARMCVKYGFETLGLEEVYCLIKEDNTASIKVAKRLEMQKVGEYPKPYKGKKISHLVFR
LEKKVWQESKNNATQGFKSCSLFKGIKQDSIVWMSHADKVESIPQGFRELAKSGNTHYCAIADSKRKIYALQFHPEVVHS
ECGGQMLQNFAVGICGANTCWNMRHFAQNEIEKLRRIVYGGKAHCENPMSFMQIQEAFKHIGKAQTIQRLVEIWEEGARA
THKDLSENEIAGMREEIREAILKSKNLLIAQKNEEWLGFIEIEKNEIAMLFVVPKAFRKGVGKALLKEAFMRYLGAFEVI
KVNSLEWALGFYQALGFAKTGKKPIPAGSAGAFSPELIPLSIARESLQKSLGLEAQDSNEGVREKVRCAWATDKDEAARK
LYEDYHDTEWGEPLHEDKKLFEHLVLEGFQAGLSWITILKKREAFRVAFDDFDPHIVANYDEDKIKELMRNEGIIRNRAK
IEAAIINAKAFMAVQREFGSFDKYIWGFVGGKPIINAFESIADLPASTPLSDKIAKDLKKRGFKFVGTTTMYAMMQSIGM
VNDHLTSCFKCNSSLGMQCDKILDFSQGTNTKSANLTKNPKNLHSHTANTRIVDSQHTESSDIKGQSHLESSADSGSAVS
LRDFKSCEGATRGSYLEGNDRSGVANSLKITKETTSKVLCAVSGGVDSSVVAALLYRAIGENLIPVFVDTGLLRKGEREA
VEKIFKENLKVPLITADASELFLSRLKGVLDPEIKRKIIGETFIEVFEKEAKKHNTKGEIKFLAQGTLYPDVIESVSVKG
PSKTIKSHHNVGGLPEWMKFELIEPLRELFKDEVRALGRELGMPESMLMRHPFPGPGLAIRIMGEVNKADLDLLREADSI
FIDELHKQSYYDKVWQAFCVLLNVRSVGVMGDNRTYDNTICVRAVEAIDGMTATFAHLPHDFLEGVSNRIINEVEGINRV
VYDITSKPPGTIEWE

Specific function: Catalyzes the synthesis of GMP from XMP

COG id: COG0519

COG function: function code F; GMP synthase, PP-ATPase domain/subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains

Homologues:

Organism=Homo sapiens, GI4504035, Length=401, Percent_Identity=33.1670822942643, Blast_Score=163, Evalue=1e-39,
Organism=Escherichia coli, GI1788854, Length=300, Percent_Identity=62.6666666666667, Blast_Score=367, Evalue=1e-102,
Organism=Escherichia coli, GI1789971, Length=182, Percent_Identity=47.2527472527472, Blast_Score=186, Evalue=8e-48,
Organism=Escherichia coli, GI1790442, Length=131, Percent_Identity=29.7709923664122, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71992717, Length=352, Percent_Identity=35.2272727272727, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71992710, Length=352, Percent_Identity=35.2272727272727, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI133901714, Length=352, Percent_Identity=35.2272727272727, Blast_Score=167, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6323873, Length=360, Percent_Identity=52.7777777777778, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI281365319, Length=336, Percent_Identity=34.8214285714286, Blast_Score=145, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GUAA_HELHP (Q7VG78)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_860975.1
- ProteinModelPortal:   Q7VG78
- GeneID:   1493132
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH1444
- NMPDR:   fig|235279.1.peg.1444
- BioCyc:   HHEP235279:HH_1444-MONOMER
- BRENDA:   6.3.5.2
- HAMAP:   MF_00344
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.630.30
- Gene3D:   G3DSA:1.10.340.30
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR00099
- TIGRFAMs:   TIGR00884

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C; SSF55729 Acyl_CoA_acyltransferase; SSF48150 DNA_glycsylse

EC number: =6.3.5.2

Molecular weight: Translated: 154162; Mature: 154162

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS51273 GATASE_TYPE_1; PS51186 GNAT; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 84-84 ACT_SITE 554-554 ACT_SITE 556-556

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQENNVQILVLDFGSQYTQLIARRLREYGVYTEIVPYFEKLDSIKSKNPKGIILSGGPAS
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
VYEKDAYKPDSAIFTLGIPILGICYGMQLIAQHFGGRVIKADAQEFGKAVLEIMESSQDS
HHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHCCCCC
KDSSCFAFQGASQGIQAPMTLSFDIFSHHKFPQMLTALLDLWEDSVQASHIFLTKQHIAE
CCCCEEEECCCCCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEHHHHHH
IRLEVKAALQSSQNIITATDKKDFLGFIGVEKNKIEMLFVASSVFRKGIGKALLKEALER
HHHHHHHHHHCCCCEEEECCCHHHHEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
YLKDYPYILVDCNEQNTQGLAFYKSLGFEKVGMSEKDSAGRDFPIVHLKVSKAILKKALE
HHHHCCEEEEECCCCCCCHHHHHHHCCCHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH
RGTSDSVANAFVCESERVFLRPYTQADFAALHKIVSDKETMYAWGQGFSKKQSQEWLDKQ
CCCCCCHHHHHEECCCCEEEECCCHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHH
LAHYQQYGFGIWAIIEKQSGAIIGNAGLNHTEISLKGKTQKIVEIGYLLHRDFWGKGYGS
HHHHHHHCCEEEEEEEECCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCHH
EVARMCVKYGFETLGLEEVYCLIKEDNTASIKVAKRLEMQKVGEYPKPYKGKKISHLVFR
HHHHHHHHHCCHHCCHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LEKKVWQESKNNATQGFKSCSLFKGIKQDSIVWMSHADKVESIPQGFRELAKSGNTHYCA
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEE
IADSKRKIYALQFHPEVVHSECGGQMLQNFAVGICGANTCWNMRHFAQNEIEKLRRIVYG
EECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
GKAHCENPMSFMQIQEAFKHIGKAQTIQRLVEIWEEGARATHKDLSENEIAGMREEIREA
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHH
ILKSKNLLIAQKNEEWLGFIEIEKNEIAMLFVVPKAFRKGVGKALLKEAFMRYLGAFEVI
HHCCCCEEEEECCCCEEEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEE
KVNSLEWALGFYQALGFAKTGKKPIPAGSAGAFSPELIPLSIARESLQKSLGLEAQDSNE
EECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GVREKVRCAWATDKDEAARKLYEDYHDTEWGEPLHEDKKLFEHLVLEGFQAGLSWITILK
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KREAFRVAFDDFDPHIVANYDEDKIKELMRNEGIIRNRAKIEAAIINAKAFMAVQREFGS
HHHHHEEEECCCCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
FDKYIWGFVGGKPIINAFESIADLPASTPLSDKIAKDLKKRGFKFVGTTTMYAMMQSIGM
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEECHHHHHHHHHHHCC
VNDHLTSCFKCNSSLGMQCDKILDFSQGTNTKSANLTKNPKNLHSHTANTRIVDSQHTES
HHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCCCCC
SDIKGQSHLESSADSGSAVSLRDFKSCEGATRGSYLEGNDRSGVANSLKITKETTSKVLC
CCCCCHHHHHCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEHHHHHHEEE
AVSGGVDSSVVAALLYRAIGENLIPVFVDTGLLRKGEREAVEKIFKENLKVPLITADASE
EECCCCCHHHHHHHHHHHHCCCCEEHHHCCHHHCCCCHHHHHHHHHCCCCEEEEECCHHH
LFLSRLKGVLDPEIKRKIIGETFIEVFEKEAKKHNTKGEIKFLAQGTLYPDVIESVSVKG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCC
PSKTIKSHHNVGGLPEWMKFELIEPLRELFKDEVRALGRELGMPESMLMRHPFPGPGLAI
CHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCEEE
RIMGEVNKADLDLLREADSIFIDELHKQSYYDKVWQAFCVLLNVRSVGVMGDNRTYDNTI
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHH
CVRAVEAIDGMTATFAHLPHDFLEGVSNRIINEVEGINRVVYDITSKPPGTIEWE
HHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCC
>Mature Secondary Structure
MQENNVQILVLDFGSQYTQLIARRLREYGVYTEIVPYFEKLDSIKSKNPKGIILSGGPAS
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
VYEKDAYKPDSAIFTLGIPILGICYGMQLIAQHFGGRVIKADAQEFGKAVLEIMESSQDS
HHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHCCCCC
KDSSCFAFQGASQGIQAPMTLSFDIFSHHKFPQMLTALLDLWEDSVQASHIFLTKQHIAE
CCCCEEEECCCCCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEHHHHHH
IRLEVKAALQSSQNIITATDKKDFLGFIGVEKNKIEMLFVASSVFRKGIGKALLKEALER
HHHHHHHHHHCCCCEEEECCCHHHHEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
YLKDYPYILVDCNEQNTQGLAFYKSLGFEKVGMSEKDSAGRDFPIVHLKVSKAILKKALE
HHHHCCEEEEECCCCCCCHHHHHHHCCCHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH
RGTSDSVANAFVCESERVFLRPYTQADFAALHKIVSDKETMYAWGQGFSKKQSQEWLDKQ
CCCCCCHHHHHEECCCCEEEECCCHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHH
LAHYQQYGFGIWAIIEKQSGAIIGNAGLNHTEISLKGKTQKIVEIGYLLHRDFWGKGYGS
HHHHHHHCCEEEEEEEECCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCHH
EVARMCVKYGFETLGLEEVYCLIKEDNTASIKVAKRLEMQKVGEYPKPYKGKKISHLVFR
HHHHHHHHHCCHHCCHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LEKKVWQESKNNATQGFKSCSLFKGIKQDSIVWMSHADKVESIPQGFRELAKSGNTHYCA
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEE
IADSKRKIYALQFHPEVVHSECGGQMLQNFAVGICGANTCWNMRHFAQNEIEKLRRIVYG
EECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
GKAHCENPMSFMQIQEAFKHIGKAQTIQRLVEIWEEGARATHKDLSENEIAGMREEIREA
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHH
ILKSKNLLIAQKNEEWLGFIEIEKNEIAMLFVVPKAFRKGVGKALLKEAFMRYLGAFEVI
HHCCCCEEEEECCCCEEEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEE
KVNSLEWALGFYQALGFAKTGKKPIPAGSAGAFSPELIPLSIARESLQKSLGLEAQDSNE
EECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GVREKVRCAWATDKDEAARKLYEDYHDTEWGEPLHEDKKLFEHLVLEGFQAGLSWITILK
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KREAFRVAFDDFDPHIVANYDEDKIKELMRNEGIIRNRAKIEAAIINAKAFMAVQREFGS
HHHHHEEEECCCCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
FDKYIWGFVGGKPIINAFESIADLPASTPLSDKIAKDLKKRGFKFVGTTTMYAMMQSIGM
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEECHHHHHHHHHHHCC
VNDHLTSCFKCNSSLGMQCDKILDFSQGTNTKSANLTKNPKNLHSHTANTRIVDSQHTES
HHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCCCCC
SDIKGQSHLESSADSGSAVSLRDFKSCEGATRGSYLEGNDRSGVANSLKITKETTSKVLC
CCCCCHHHHHCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEHHHHHHEEE
AVSGGVDSSVVAALLYRAIGENLIPVFVDTGLLRKGEREAVEKIFKENLKVPLITADASE
EECCCCCHHHHHHHHHHHHCCCCEEHHHCCHHHCCCCHHHHHHHHHCCCCEEEEECCHHH
LFLSRLKGVLDPEIKRKIIGETFIEVFEKEAKKHNTKGEIKFLAQGTLYPDVIESVSVKG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCC
PSKTIKSHHNVGGLPEWMKFELIEPLRELFKDEVRALGRELGMPESMLMRHPFPGPGLAI
CHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCEEE
RIMGEVNKADLDLLREADSIFIDELHKQSYYDKVWQAFCVLLNVRSVGVMGDNRTYDNTI
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHH
CVRAVEAIDGMTATFAHLPHDFLEGVSNRIINEVEGINRVVYDITSKPPGTIEWE
HHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12810954