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The map label for this gene is coaD

Identifier: 32266860

GI number: 32266860

Start: 1317288

End: 1317785

Strand: Direct

Name: coaD

Synonym: HH1361

Alternate gene names: 32266860

Gene position: 1317288-1317785 (Clockwise)

Preceding gene: 32266859

Following gene: 32266861

Centisome position: 73.22

GC content: 35.54

Gene sequence:

>498_bases
ATGAGAACATTAGCCATTTATCCGGGCACTTTTGACCCTGTAACAAATGGGCATTTGGATATTATCAAACGTTCTATGGA
GATTTTTGATAATGTAATTGTTGCTGTGGCTCAATCAAGCTCTAAACGACCAATGTTTTCGCTTCAAGAACGCATTGATA
TTTTAAAGCTTAGCACACAAAATTTAGTAAATGTGCAAGTTGAAGGTTTTTGCACTCTTCTTGCAGATTTTGCAAAGCAA
AAGGGTGCAAGAATGATTATACGAGGATTGCGGGCTGTAAGTGATTTTGAATATGAATTACAAATAGGCTACGCGAACGC
TTCGCTCAATCCAGAGCTTGAAACAATTTATTTTATGCCAACTTTAGAGAATGCATTTATTAGCTCATCAGTAGTGCGTT
CAATCATTGAACATAATGGAGCATTTTCTCACCTTGTGCCAAAAAATGCTGCTGATTTTATTTATTCACTTTATACCAAA
CATAAAAGAGGTATGTAA

Upstream 100 bases:

>100_bases
TAGAATCTATGGAGAGGTTTTTTATAGGAAAGTGGTTTGATGCACTTTGTATAGAAAATATACTTTATCAACGTTGGAAA
TATGATATAAAGGGGATTTA

Downstream 100 bases:

>100_bases
TGTATGTAGCAATTGAAGGCGTAGATACTTGTGGTAAAAGCACACAGATTCAATTACTCAAAGCGTATTACCCACAAGCT
GTTTTTACCAAAGAGCCCGG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRTLAIYPGTFDPVTNGHLDIIKRSMEIFDNVIVAVAQSSSKRPMFSLQERIDILKLSTQNLVNVQVEGFCTLLADFAKQ
KGARMIIRGLRAVSDFEYELQIGYANASLNPELETIYFMPTLENAFISSSVVRSIIEHNGAFSHLVPKNAADFIYSLYTK
HKRGM

Sequences:

>Translated_165_residues
MRTLAIYPGTFDPVTNGHLDIIKRSMEIFDNVIVAVAQSSSKRPMFSLQERIDILKLSTQNLVNVQVEGFCTLLADFAKQ
KGARMIIRGLRAVSDFEYELQIGYANASLNPELETIYFMPTLENAFISSSVVRSIIEHNGAFSHLVPKNAADFIYSLYTK
HKRGM
>Mature_165_residues
MRTLAIYPGTFDPVTNGHLDIIKRSMEIFDNVIVAVAQSSSKRPMFSLQERIDILKLSTQNLVNVQVEGFCTLLADFAKQ
KGARMIIRGLRAVSDFEYELQIGYANASLNPELETIYFMPTLENAFISSSVVRSIIEHNGAFSHLVPKNAADFIYSLYTK
HKRGM

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=149, Percent_Identity=51.6778523489933, Blast_Score=181, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_HELHP (Q7VGG0)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_860892.1
- ProteinModelPortal:   Q7VGG0
- SMR:   Q7VGG0
- GeneID:   1493049
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH1361
- NMPDR:   fig|235279.1.peg.1361
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   HHEP235279:HH_1361-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18579; Mature: 18579

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLAIYPGTFDPVTNGHLDIIKRSMEIFDNVIVAVAQSSSKRPMFSLQERIDILKLSTQ
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
NLVNVQVEGFCTLLADFAKQKGARMIIRGLRAVSDFEYELQIGYANASLNPELETIYFMP
CEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEEEEEE
TLENAFISSSVVRSIIEHNGAFSHLVPKNAADFIYSLYTKHKRGM
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTLAIYPGTFDPVTNGHLDIIKRSMEIFDNVIVAVAQSSSKRPMFSLQERIDILKLSTQ
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
NLVNVQVEGFCTLLADFAKQKGARMIIRGLRAVSDFEYELQIGYANASLNPELETIYFMP
CEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEEEEEE
TLENAFISSSVVRSIIEHNGAFSHLVPKNAADFIYSLYTKHKRGM
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954