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The map label for this gene is sdaC

Identifier: 32266599

GI number: 32266599

Start: 1070053

End: 1071432

Strand: Direct

Name: sdaC

Synonym: HH1100

Alternate gene names: 32266599

Gene position: 1070053-1071432 (Clockwise)

Preceding gene: 32266598

Following gene: 32266604

Centisome position: 59.48

GC content: 35.14

Gene sequence:

>1380_bases
ATGAACAAATGGAATAACTTTGATACAAGCTGGATAATTTCTCTTTTTGGAACAGCTGTGGGTGCTGGGATTTTATATCT
GCCAATTAAAGCAGGTGGAGGGGGAATCTGGCCTGTAATAGCAATGTGTTTTATTATATTTCCTATGGTTTATCTTAGCC
ATCGCGCACTTAGTCGTTTTGTATGTCAAGCAAATGGTAATGATAAAGATATTACATACGCCGCTGAAGAATATTTTGGT
CGCAATGTAAGTATATTTATCTCAATTCTCTATTTTTTTGCAATTTTTCCTATTTGTCTCGCATATTGCGTAGGCATTAC
AAACACATTTGAAAGTTTTATTTATCATCAGATTCTCCCACTTGTCAATGAAAATCACCCGGCAGTTGCTCCACTTGGGA
CTTTAGCTGGATTTATACAAGACATTTATTACGACCCATATAGTTTTCTCCACCAAAGCGAATCTGGAGCACTCCTTAAA
CTTAAATCTGAAAATTATGCTACTTTGCACCCATTTTGGCGAGCTGGGCTTGTTTTTATCTTGGTAAGTGCTTTTATGCT
TATTATGCTTTTTAGTGAAAAACTTATCATAAAAGTGTGCCAATGGCTTGTATATCCTCTTTGTGCTATTTTATTTATAT
TTTCACTCTATCTTATTCCCCAATGGAATCTTGAAAGCATTACATTTGTACCCGATATAGAAGATTTTTTGATAATTGTA
TGGCTTACACTTCCCGTGCTTGTATTTTCTTTTAATCACTCTCCTGCTATTTCTACCTTTGCGCTAAGTGCTAAGCGCGA
ATATGGAGCAGATGCTATCATAAAATCAGATTCTATACTTTTGCGCACTTCAATTATGCTTCTTGTCTTTGTAATGTTTT
TTGTCATCTCTTGTGTGCTCTCTCTTACACCACAAGAGCTTATAGAAGCTAGAGCACAAAATATCCCCGTGCTCTCATAT
TTTGCCAATAAACTTGATAATCCATTGATTTCCTATGGTGGTCCTTTGATTGCATTTTTGGCAATTTCTAGTTCATTTTT
TGGGCATTATTTTGGTGCACGTGAGGGTGCATATGGCATTGTAAGGAAATGTTGCAAAATTGCGGGAAACAAAGAGCCAA
ATCTCAAACTTATTGCAGCAATATGCACATTTGTAATGTATGTTATTATGCTTATTACTGCCTATATCAATCCAAGCGTT
TTAGGGTTTATTGAGGATTTAGGAGGTCCGATTATTGCAGCTATCCTTTTTCTTATGCCTATTATTGCTATTTATAGCGT
ATCTAAGATGAAACAATTCAAAAACCCAGCTCTTGATGCTTTTGTCTTTATAACAGGGCTTTTAACAATATTTACTATTA
CTTATAAGCTCATATTGTAA

Upstream 100 bases:

>100_bases
GAATGGATGAAATTCTATGTTTCATTGCGTAGATTGATAAAAAAAGATTCTAAAAAGCTATAATGAAACTAAAAATATCA
TTGTCTTAAAAGGATACCGA

Downstream 100 bases:

>100_bases
GATATTTATTTGGATTCTTGATTCTCTAAATGTGTGATATTAAACACAATAAATTTATAGCACACATATATAATGCCAAT
CCACAAAATAAGCATAAAAA

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MNKWNNFDTSWIISLFGTAVGAGILYLPIKAGGGGIWPVIAMCFIIFPMVYLSHRALSRFVCQANGNDKDITYAAEEYFG
RNVSIFISILYFFAIFPICLAYCVGITNTFESFIYHQILPLVNENHPAVAPLGTLAGFIQDIYYDPYSFLHQSESGALLK
LKSENYATLHPFWRAGLVFILVSAFMLIMLFSEKLIIKVCQWLVYPLCAILFIFSLYLIPQWNLESITFVPDIEDFLIIV
WLTLPVLVFSFNHSPAISTFALSAKREYGADAIIKSDSILLRTSIMLLVFVMFFVISCVLSLTPQELIEARAQNIPVLSY
FANKLDNPLISYGGPLIAFLAISSSFFGHYFGAREGAYGIVRKCCKIAGNKEPNLKLIAAICTFVMYVIMLITAYINPSV
LGFIEDLGGPIIAAILFLMPIIAIYSVSKMKQFKNPALDAFVFITGLLTIFTITYKLIL

Sequences:

>Translated_459_residues
MNKWNNFDTSWIISLFGTAVGAGILYLPIKAGGGGIWPVIAMCFIIFPMVYLSHRALSRFVCQANGNDKDITYAAEEYFG
RNVSIFISILYFFAIFPICLAYCVGITNTFESFIYHQILPLVNENHPAVAPLGTLAGFIQDIYYDPYSFLHQSESGALLK
LKSENYATLHPFWRAGLVFILVSAFMLIMLFSEKLIIKVCQWLVYPLCAILFIFSLYLIPQWNLESITFVPDIEDFLIIV
WLTLPVLVFSFNHSPAISTFALSAKREYGADAIIKSDSILLRTSIMLLVFVMFFVISCVLSLTPQELIEARAQNIPVLSY
FANKLDNPLISYGGPLIAFLAISSSFFGHYFGAREGAYGIVRKCCKIAGNKEPNLKLIAAICTFVMYVIMLITAYINPSV
LGFIEDLGGPIIAAILFLMPIIAIYSVSKMKQFKNPALDAFVFITGLLTIFTITYKLIL
>Mature_459_residues
MNKWNNFDTSWIISLFGTAVGAGILYLPIKAGGGGIWPVIAMCFIIFPMVYLSHRALSRFVCQANGNDKDITYAAEEYFG
RNVSIFISILYFFAIFPICLAYCVGITNTFESFIYHQILPLVNENHPAVAPLGTLAGFIQDIYYDPYSFLHQSESGALLK
LKSENYATLHPFWRAGLVFILVSAFMLIMLFSEKLIIKVCQWLVYPLCAILFIFSLYLIPQWNLESITFVPDIEDFLIIV
WLTLPVLVFSFNHSPAISTFALSAKREYGADAIIKSDSILLRTSIMLLVFVMFFVISCVLSLTPQELIEARAQNIPVLSY
FANKLDNPLISYGGPLIAFLAISSSFFGHYFGAREGAYGIVRKCCKIAGNKEPNLKLIAAICTFVMYVIMLITAYINPSV
LGFIEDLGGPIIAAILFLMPIIAIYSVSKMKQFKNPALDAFVFITGLLTIFTITYKLIL

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=462, Percent_Identity=41.7748917748918, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI1789504, Length=478, Percent_Identity=34.3096234309623, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1789211, Length=452, Percent_Identity=29.646017699115, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1789961, Length=437, Percent_Identity=24.4851258581236, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI145693183, Length=458, Percent_Identity=23.1441048034935, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 51371; Mature: 51371

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKWNNFDTSWIISLFGTAVGAGILYLPIKAGGGGIWPVIAMCFIIFPMVYLSHRALSRF
CCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VCQANGNDKDITYAAEEYFGRNVSIFISILYFFAIFPICLAYCVGITNTFESFIYHQILP
HHHCCCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVNENHPAVAPLGTLAGFIQDIYYDPYSFLHQSESGALLKLKSENYATLHPFWRAGLVFI
HHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEECCCCCCEECHHHHHHHHHH
LVSAFMLIMLFSEKLIIKVCQWLVYPLCAILFIFSLYLIPQWNLESITFVPDIEDFLIIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHH
WLTLPVLVFSFNHSPAISTFALSAKREYGADAIIKSDSILLRTSIMLLVFVMFFVISCVL
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
SLTPQELIEARAQNIPVLSYFANKLDNPLISYGGPLIAFLAISSSFFGHYFGAREGAYGI
HCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHH
VRKCCKIAGNKEPNLKLIAAICTFVMYVIMLITAYINPSVLGFIEDLGGPIIAAILFLMP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHH
IIAIYSVSKMKQFKNPALDAFVFITGLLTIFTITYKLIL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKWNNFDTSWIISLFGTAVGAGILYLPIKAGGGGIWPVIAMCFIIFPMVYLSHRALSRF
CCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VCQANGNDKDITYAAEEYFGRNVSIFISILYFFAIFPICLAYCVGITNTFESFIYHQILP
HHHCCCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVNENHPAVAPLGTLAGFIQDIYYDPYSFLHQSESGALLKLKSENYATLHPFWRAGLVFI
HHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEECCCCCCEECHHHHHHHHHH
LVSAFMLIMLFSEKLIIKVCQWLVYPLCAILFIFSLYLIPQWNLESITFVPDIEDFLIIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHH
WLTLPVLVFSFNHSPAISTFALSAKREYGADAIIKSDSILLRTSIMLLVFVMFFVISCVL
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
SLTPQELIEARAQNIPVLSYFANKLDNPLISYGGPLIAFLAISSSFFGHYFGAREGAYGI
HCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHH
VRKCCKIAGNKEPNLKLIAAICTFVMYVIMLITAYINPSVLGFIEDLGGPIIAAILFLMP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHH
IIAIYSVSKMKQFKNPALDAFVFITGLLTIFTITYKLIL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]