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The map label for this gene is murG

Identifier: 32266426

GI number: 32266426

Start: 898426

End: 899478

Strand: Direct

Name: murG

Synonym: HH0927

Alternate gene names: 32266426

Gene position: 898426-899478 (Clockwise)

Preceding gene: 32266423

Following gene: 32266427

Centisome position: 49.94

GC content: 36.56

Gene sequence:

>1053_bases
ATGTTTGCAATTACAGGAGGAGGAACAGGTGGACACTTAGCTATTGCCAAAGCACTTGCACAAGAAGCCCAAAAAAACAA
TCAACAATCAATTTATATTGGCTCACAGATAGGACAAGATAAAACGTGGTTTGAAGGAAGCTCACTTTTTACGCATTGTT
ATTTCTTAGATTCAACAGGAGTGGTGAATAAAAAGGGTTTGGGTAAAATCAAAGCTATTTTTAAACAACTTAAAGCAGCG
TGGGAAGCGCGAAATATCCTTAAAAAACACAAGATTGAATATGTTATTAGTGTCGGAGGCTTTAGTGCAGGAGGAGCGAG
CATAGGTGCAATTTTAAGTAATACACCCCTTTTTATCCACGAACAAAATGCCATTAAAGGCAAACTCAATGAGATTCTCA
CTCCCTTCGCAAAAGCTATATTTGGTAGCTTTGAGGGCAAAAGCAAAAACTTTATTCACACTTCATATCCTGTGCGTGAT
GAATTTTTTACCCATTCACGAGTGCGTGAAAAGCTACACCACCTCCTCTTTTTGGGTGGATCTCAAGGTGCAAAAGGAAT
CAATGACTTTGCTTTACAAATTGTGCCAGAATTATTAAAAAGAGGGATTACTATCGCTCATCAATGTGGAGAAAGAGACT
TTGAACGTATCAAAAAAGCTTATGAGCATATTGGCATATTGGATAAGGTTGATGTTTTTGCCTTTGATAAAGAAATTGTA
TTGCGTTTGCAAAAGGCAGATTTGTGCATTGCGCGTTCAGGTGCTTCAAGTCTATGGGAAATGAGTGCAAATGGACTTAT
TGGGATATTTGTCCCCTACCCATATGCAGCAAAAGATCATCAATACTATAATGCTTTGCATTTTACCAAACAAGGATTGG
GATTACTTCTTAGAGAATCGCAACTTGATATGCTACGAGTTTTTACATTTATAGAATCTTTACAAAAACAAGAAGACTCA
TTAAGTGAAAAATCTCATTTGCTAATGAGCAAAATACAACCTAATGGAGCAAAAGAGATTTTAGAGCATATTACATCTTT
GATGTCTCATTAA

Upstream 100 bases:

>100_bases
CTTAACTTAATGCCATATTTGATATTTTTTATTACAATGCAAAAGATAATGACAATGGCATATTTGCCTTAAAATCAGAA
TCTCGCACAAAGGAAAAATA

Downstream 100 bases:

>100_bases
AAGCAAGCTTATATTTTACCCTTTAAATAACTTGCTTTAATAAAGTTTGCTATACTTTTACCGACCCTTTCATCTAGCTG
GCCAAGGATATCACCCTTTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MFAITGGGTGGHLAIAKALAQEAQKNNQQSIYIGSQIGQDKTWFEGSSLFTHCYFLDSTGVVNKKGLGKIKAIFKQLKAA
WEARNILKKHKIEYVISVGGFSAGGASIGAILSNTPLFIHEQNAIKGKLNEILTPFAKAIFGSFEGKSKNFIHTSYPVRD
EFFTHSRVREKLHHLLFLGGSQGAKGINDFALQIVPELLKRGITIAHQCGERDFERIKKAYEHIGILDKVDVFAFDKEIV
LRLQKADLCIARSGASSLWEMSANGLIGIFVPYPYAAKDHQYYNALHFTKQGLGLLLRESQLDMLRVFTFIESLQKQEDS
LSEKSHLLMSKIQPNGAKEILEHITSLMSH

Sequences:

>Translated_350_residues
MFAITGGGTGGHLAIAKALAQEAQKNNQQSIYIGSQIGQDKTWFEGSSLFTHCYFLDSTGVVNKKGLGKIKAIFKQLKAA
WEARNILKKHKIEYVISVGGFSAGGASIGAILSNTPLFIHEQNAIKGKLNEILTPFAKAIFGSFEGKSKNFIHTSYPVRD
EFFTHSRVREKLHHLLFLGGSQGAKGINDFALQIVPELLKRGITIAHQCGERDFERIKKAYEHIGILDKVDVFAFDKEIV
LRLQKADLCIARSGASSLWEMSANGLIGIFVPYPYAAKDHQYYNALHFTKQGLGLLLRESQLDMLRVFTFIESLQKQEDS
LSEKSHLLMSKIQPNGAKEILEHITSLMSH
>Mature_350_residues
MFAITGGGTGGHLAIAKALAQEAQKNNQQSIYIGSQIGQDKTWFEGSSLFTHCYFLDSTGVVNKKGLGKIKAIFKQLKAA
WEARNILKKHKIEYVISVGGFSAGGASIGAILSNTPLFIHEQNAIKGKLNEILTPFAKAIFGSFEGKSKNFIHTSYPVRD
EFFTHSRVREKLHHLLFLGGSQGAKGINDFALQIVPELLKRGITIAHQCGERDFERIKKAYEHIGILDKVDVFAFDKEIV
LRLQKADLCIARSGASSLWEMSANGLIGIFVPYPYAAKDHQYYNALHFTKQGLGLLLRESQLDMLRVFTFIESLQKQEDS
LSEKSHLLMSKIQPNGAKEILEHITSLMSH

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=312, Percent_Identity=29.4871794871795, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_HELHP (Q7U322)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_860458.1
- ProteinModelPortal:   Q7U322
- GeneID:   1492616
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0927
- NMPDR:   fig|235279.1.peg.927
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   HHEP235279:HH_0927-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38908; Mature: 38908

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAITGGGTGGHLAIAKALAQEAQKNNQQSIYIGSQIGQDKTWFEGSSLFTHCYFLDSTG
CEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCEEEEEEECCCC
VVNKKGLGKIKAIFKQLKAAWEARNILKKHKIEYVISVGGFSAGGASIGAILSNTPLFIH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHCCCCEEEE
EQNAIKGKLNEILTPFAKAIFGSFEGKSKNFIHTSYPVRDEFFTHSRVREKLHHLLFLGG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHEEECC
SQGAKGINDFALQIVPELLKRGITIAHQCGERDFERIKKAYEHIGILDKVDVFAFDKEIV
CCCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHEECHHHH
LRLQKADLCIARSGASSLWEMSANGLIGIFVPYPYAAKDHQYYNALHFTKQGLGLLLRES
HHHHHHCEEEECCCCHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCHHHHHHHH
QLDMLRVFTFIESLQKQEDSLSEKSHLLMSKIQPNGAKEILEHITSLMSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFAITGGGTGGHLAIAKALAQEAQKNNQQSIYIGSQIGQDKTWFEGSSLFTHCYFLDSTG
CEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCEEEEEEECCCC
VVNKKGLGKIKAIFKQLKAAWEARNILKKHKIEYVISVGGFSAGGASIGAILSNTPLFIH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHCCCCEEEE
EQNAIKGKLNEILTPFAKAIFGSFEGKSKNFIHTSYPVRDEFFTHSRVREKLHHLLFLGG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHEEECC
SQGAKGINDFALQIVPELLKRGITIAHQCGERDFERIKKAYEHIGILDKVDVFAFDKEIV
CCCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHEECHHHH
LRLQKADLCIARSGASSLWEMSANGLIGIFVPYPYAAKDHQYYNALHFTKQGLGLLLRES
HHHHHHCEEEECCCCHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCHHHHHHHH
QLDMLRVFTFIESLQKQEDSLSEKSHLLMSKIQPNGAKEILEHITSLMSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12810954