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The map label for this gene is rppH [H]

Identifier: 32266116

GI number: 32266116

Start: 595982

End: 596416

Strand: Direct

Name: rppH [H]

Synonym: HH0617

Alternate gene names: 32266116

Gene position: 595982-596416 (Clockwise)

Preceding gene: 32266115

Following gene: 32266117

Centisome position: 33.13

GC content: 32.87

Gene sequence:

>435_bases
GTGATTCTCTCAAGTGTATATCCAAAAGAATGCCGATTTTTTATTGCGCAACGTTTAGATATTAAAGATGTATGGCAATT
CCCTCAAGGAGGTATTGATGAAGGAGAAAGTCCTCGTGATGCGCTTTTTCGTGAATTGCGAGAGGAAATAGGCACAGATG
AAATAGAAATTATTAGTGAATGCCCAGAATGGATACAATATGATTTTCCCAAAAGTATGTCAAAAAAAAAGTATAAAGGC
TTTGCAGGACAGATTCAGAAATATTTTTTGGTGCGACTTAAAAATGATGCTGCTATTAATATCAAAACCAAAGAACCAGA
ATTTAACAAATATGAATTTGTCAGTAGAAAAAAACTCCTAGAGTGCGTAACACCTTTTAAAAAAGGAGTATATAAGCAAG
TTTTAGAGTATTTTAAAAAAGAAGGTTATCTCTAG

Upstream 100 bases:

>100_bases
TTTATAGAATCTAAAAGGCAAAGGTATGAAATCATCTTGCACACAAGAAAAATTACAACAAGATGCCCCTATTAAAAAGT
ATCGTCCCAATGTTGCTGCT

Downstream 100 bases:

>100_bases
TGATATATTTTAAGGAAGAACATTTTATGATTACGCCTTTATTTTACACTCAAGGATATATATGCTAATCGTGCAAAAAT
ATGGTGGCACGAGTATGGGA

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MILSSVYPKECRFFIAQRLDIKDVWQFPQGGIDEGESPRDALFRELREEIGTDEIEIISECPEWIQYDFPKSMSKKKYKG
FAGQIQKYFLVRLKNDAAINIKTKEPEFNKYEFVSRKKLLECVTPFKKGVYKQVLEYFKKEGYL

Sequences:

>Translated_144_residues
MILSSVYPKECRFFIAQRLDIKDVWQFPQGGIDEGESPRDALFRELREEIGTDEIEIISECPEWIQYDFPKSMSKKKYKG
FAGQIQKYFLVRLKNDAAINIKTKEPEFNKYEFVSRKKLLECVTPFKKGVYKQVLEYFKKEGYL
>Mature_144_residues
MILSSVYPKECRFFIAQRLDIKDVWQFPQGGIDEGESPRDALFRELREEIGTDEIEIISECPEWIQYDFPKSMSKKKYKG
FAGQIQKYFLVRLKNDAAINIKTKEPEFNKYEFVSRKKLLECVTPFKKGVYKQVLEYFKKEGYL

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=119, Percent_Identity=40.3361344537815, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 17114; Mature: 17114

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSSVYPKECRFFIAQRLDIKDVWQFPQGGIDEGESPRDALFRELREEIGTDEIEIISE
CCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
CPEWIQYDFPKSMSKKKYKGFAGQIQKYFLVRLKNDAAINIKTKEPEFNKYEFVSRKKLL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHH
ECVTPFKKGVYKQVLEYFKKEGYL
HHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MILSSVYPKECRFFIAQRLDIKDVWQFPQGGIDEGESPRDALFRELREEIGTDEIEIISE
CCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
CPEWIQYDFPKSMSKKKYKGFAGQIQKYFLVRLKNDAAINIKTKEPEFNKYEFVSRKKLL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHH
ECVTPFKKGVYKQVLEYFKKEGYL
HHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA