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The map label for this gene is glyQ

Identifier: 32266030

GI number: 32266030

Start: 511258

End: 512154

Strand: Direct

Name: glyQ

Synonym: HH0531

Alternate gene names: 32266030

Gene position: 511258-512154 (Clockwise)

Preceding gene: 32266029

Following gene: 32266031

Centisome position: 28.42

GC content: 38.24

Gene sequence:

>897_bases
ATGTTAAGTTTTTCAGATATTTTATTAAAATTACAAGAATTTTGGAAAAATCAAGGCTGCCTCATTGTCCAGCCTTATGA
CATTCCTGCAGGAGCTGGGACATTCCACCCTGCAACCCTACTTAGAAGTCTTGATTCTAAGCCGTGGAATGTAGCTTATG
TCGCACCTTCACGCCGCCCCACAGATGGACGATACGGAGAAAATCCTAACCGCTTAGGAAGTTACTATCAATTTCAAGTG
CTTATCAAACCAAGTCCTGATAATATACAAGAGCTCTACTTACGTAGCCTTGAGGCTTTAGGATTAGATTTAAAATCACA
CGATGTGCGATTTGTAGAAGATAATTGGGAATCTCCAACGCTTGGTGCGTGGGGATTAGGCTGGGAAGTATGGCTTGATG
GTATGGAAGTAACTCAATTCACTTACTTTCAACAAGTAGGAGGTATCCCTTGTCGCCCTGTAGCAGTAGAAATCACTTAT
GGAGTGGAGCGTTTAGCAATGTATATTCAAAGTGTAGAAAATATCTTTGATATTCTTTGGAATGATTCCTCAAACTCTGC
ACCTATGCTTTATGCTGATGTTCATTTGCAAAGCGAATATGAATTTTCTAAATACCATTTTGAGCTTGCTGATACACAAA
TGATTTTTTCTCTCTTTAATCAATACACTCAAGAAGTCAAACATTGTTTGCAACAAAAAGTCCCTCTTGTAGCCTATGAT
TACACAATGTTAGCAAGTCATTTTTTTAATATCCTTGATGCGCGTAAAGCTATCTCTGTAGCTCAAAGACAAAACTATAT
CTTACAAATACGCGAACTCGCTAAAGGCTGTGCCACACTCTATAAAGAAATGGAAGAAGAGAGAACTATGCGAAGAGAAA
AAAACAAAGGATTATGA

Upstream 100 bases:

>100_bases
TTTTTATGCTTTTTAAAGTCAAATGCGATGTTGTAGCTGCATTTTGTGGTGTGGAAAAAGGCACAATGATGTTAAAGCAT
AATGTCAAATAAGGAGAAAT

Downstream 100 bases:

>100_bases
TGCGCCTTTTTCTGATTTTAATTTTTATATTTAGCATACTTCACGCGGAGAATCTTGTGCGTGATTTTGAACTTTATAAA
CTCAATGATGGAGACAAAAG

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLSFSDILLKLQEFWKNQGCLIVQPYDIPAGAGTFHPATLLRSLDSKPWNVAYVAPSRRPTDGRYGENPNRLGSYYQFQV
LIKPSPDNIQELYLRSLEALGLDLKSHDVRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIPCRPVAVEITY
GVERLAMYIQSVENIFDILWNDSSNSAPMLYADVHLQSEYEFSKYHFELADTQMIFSLFNQYTQEVKHCLQQKVPLVAYD
YTMLASHFFNILDARKAISVAQRQNYILQIRELAKGCATLYKEMEEERTMRREKNKGL

Sequences:

>Translated_298_residues
MLSFSDILLKLQEFWKNQGCLIVQPYDIPAGAGTFHPATLLRSLDSKPWNVAYVAPSRRPTDGRYGENPNRLGSYYQFQV
LIKPSPDNIQELYLRSLEALGLDLKSHDVRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIPCRPVAVEITY
GVERLAMYIQSVENIFDILWNDSSNSAPMLYADVHLQSEYEFSKYHFELADTQMIFSLFNQYTQEVKHCLQQKVPLVAYD
YTMLASHFFNILDARKAISVAQRQNYILQIRELAKGCATLYKEMEEERTMRREKNKGL
>Mature_298_residues
MLSFSDILLKLQEFWKNQGCLIVQPYDIPAGAGTFHPATLLRSLDSKPWNVAYVAPSRRPTDGRYGENPNRLGSYYQFQV
LIKPSPDNIQELYLRSLEALGLDLKSHDVRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIPCRPVAVEITY
GVERLAMYIQSVENIFDILWNDSSNSAPMLYADVHLQSEYEFSKYHFELADTQMIFSLFNQYTQEVKHCLQQKVPLVAYD
YTMLASHFFNILDARKAISVAQRQNYILQIRELAKGCATLYKEMEEERTMRREKNKGL

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=281, Percent_Identity=61.5658362989324, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_HELHP (Q7VIS3)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_860062.1
- HSSP:   Q9WY59
- ProteinModelPortal:   Q7VIS3
- SMR:   Q7VIS3
- GeneID:   1493585
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0531
- NMPDR:   fig|235279.1.peg.531
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BioCyc:   HHEP235279:HH_0531-MONOMER
- BRENDA:   6.1.1.14
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 34513; Mature: 34513

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFSDILLKLQEFWKNQGCLIVQPYDIPAGAGTFHPATLLRSLDSKPWNVAYVAPSRRP
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCC
TDGRYGENPNRLGSYYQFQVLIKPSPDNIQELYLRSLEALGLDLKSHDVRFVEDNWESPT
CCCCCCCCHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
LGAWGLGWEVWLDGMEVTQFTYFQQVGGIPCRPVAVEITYGVERLAMYIQSVENIFDILW
CCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHC
NDSSNSAPMLYADVHLQSEYEFSKYHFELADTQMIFSLFNQYTQEVKHCLQQKVPLVAYD
CCCCCCCCEEEEEEEECCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEH
YTMLASHFFNILDARKAISVAQRQNYILQIRELAKGCATLYKEMEEERTMRREKNKGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSFSDILLKLQEFWKNQGCLIVQPYDIPAGAGTFHPATLLRSLDSKPWNVAYVAPSRRP
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCC
TDGRYGENPNRLGSYYQFQVLIKPSPDNIQELYLRSLEALGLDLKSHDVRFVEDNWESPT
CCCCCCCCHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
LGAWGLGWEVWLDGMEVTQFTYFQQVGGIPCRPVAVEITYGVERLAMYIQSVENIFDILW
CCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHC
NDSSNSAPMLYADVHLQSEYEFSKYHFELADTQMIFSLFNQYTQEVKHCLQQKVPLVAYD
CCCCCCCCEEEEEEEECCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEH
YTMLASHFFNILDARKAISVAQRQNYILQIRELAKGCATLYKEMEEERTMRREKNKGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954