Click here to switch to the map view.

The map label for this gene is kefB_1

Identifier: 32265970

GI number: 32265970

Start: 454728

End: 455912

Strand: Direct

Name: kefB_1

Synonym: HH0471

Alternate gene names: 32265970

Gene position: 454728-455912 (Clockwise)

Preceding gene: 32265969

Following gene: 32265971

Centisome position: 25.27

GC content: 35.86

Gene sequence:

>1185_bases
ATGAGTTATCCCATTGAAACACTCAGTGCTTTTAGCATTTTTGTTCTCCTTATTCTATTTGCTTCGCCTATTAGTAGCCT
TACGCGTATTCCTATTGTAGTAGTAGAGATGATTTTAGGAGCTATTGCTGCACATTTTTTTACTTTCCTTAATGATTCTC
AAGAAATACACATTGTCGCAGAAATAGGATTTTTATTTTTAATGTTTTTATGCGGTTTGGAAGTAGATATTAAATCTTTT
GCAAAGCTTGGCAAACCCTTTTTGCTTCAAACTCTAGCATATTTTTGCACACTCTATGGCATTACTTGCATCGTTGTTTT
TAGCGCAAAAATTTCTTATGTGTATATTGCAGCATTTCCTGTTATGAGCTTAGGTATGATTGTAGCGCTTATTAAGGATT
ATGGCAAAGACCAACCTTGGCTTGATTTGGCACTCAAAATTGGTATCTTGGGAGAATTAGTAAGTATTGCCGCACTTGTA
ATTATTGATGGTGCATCGCGGCACGGAGTGGGAAGTGAGCTGGGAAGAAAACTCCTTATGCTTGGACTTTTCTTGCTTTT
TGTCATCTTTGGTTTTAAAATTGCAAAAGTCATTTTTTGGTGGATACCTCAGGTAAGATTCTTATTTTTGCCAAACGATG
ATAGCAATTCTCAAGACTTACGATTTGTCTTTATGTTACTTTTTGGCTTCGTGCTTTTAATGATGTTCTTAGAAATTAAA
GCTGTGCTTGGAGCATTTTTAGCCGGAACGATTCTCGCTACATTTTTTAAACATAAAGCCGAATTACCCGAAAAACTCAA
TCATTTTGGATTTGGGTTCTTTGTGCCTTTTTTCTTTGTGCACGTGGGCTCTACACTCAATCTCAATGCAGTATTTAGGG
ATACACAGATTCTCTATCACGCTTTATATCTTGTCATCGGTATGCTTACATTGCGCCTCATTAGTGCAAGTATTGTCTTT
GGTAAATATTTTAAAAGTGCAAAATTTACACTCCTTTTTGCGCTAAGCGATTCTATGCCACTTACCTTTCTTATCGCCAC
TGCTACTTTAGGTAAAAGTATCGGGGAACTCAATGATACGCTTTATGCATCATTTGTGCTTGGTGCGATTTTAGAGGGTA
TTATTTTTAGTGTGCTTATTAAAATTGTATATGTATTTTGGAAAACACCCCAAAAGGAGAAATAA

Upstream 100 bases:

>100_bases
TTGAATCTAAAATCCACGCCCTTGAATATTCTCTCTATCCACGCGCTATTTTGCTCGCACTTGGGTTAAAAGACTTAAAC
AAAAGTGTAGAGGAATCAAA

Downstream 100 bases:

>100_bases
TGCAAAATCCTGCCCCTACTCGCCAAACTTGGAGCTCTAGTCTCACTTATGTTTTAACCGTTGCAGGAGCGACTATTGGC
TTTGGAGCAACTTGGAGATT

Product: hypothetical protein

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSYPIETLSAFSIFVLLILFASPISSLTRIPIVVVEMILGAIAAHFFTFLNDSQEIHIVAEIGFLFLMFLCGLEVDIKSF
AKLGKPFLLQTLAYFCTLYGITCIVVFSAKISYVYIAAFPVMSLGMIVALIKDYGKDQPWLDLALKIGILGELVSIAALV
IIDGASRHGVGSELGRKLLMLGLFLLFVIFGFKIAKVIFWWIPQVRFLFLPNDDSNSQDLRFVFMLLFGFVLLMMFLEIK
AVLGAFLAGTILATFFKHKAELPEKLNHFGFGFFVPFFFVHVGSTLNLNAVFRDTQILYHALYLVIGMLTLRLISASIVF
GKYFKSAKFTLLFALSDSMPLTFLIATATLGKSIGELNDTLYASFVLGAILEGIIFSVLIKIVYVFWKTPQKEK

Sequences:

>Translated_394_residues
MSYPIETLSAFSIFVLLILFASPISSLTRIPIVVVEMILGAIAAHFFTFLNDSQEIHIVAEIGFLFLMFLCGLEVDIKSF
AKLGKPFLLQTLAYFCTLYGITCIVVFSAKISYVYIAAFPVMSLGMIVALIKDYGKDQPWLDLALKIGILGELVSIAALV
IIDGASRHGVGSELGRKLLMLGLFLLFVIFGFKIAKVIFWWIPQVRFLFLPNDDSNSQDLRFVFMLLFGFVLLMMFLEIK
AVLGAFLAGTILATFFKHKAELPEKLNHFGFGFFVPFFFVHVGSTLNLNAVFRDTQILYHALYLVIGMLTLRLISASIVF
GKYFKSAKFTLLFALSDSMPLTFLIATATLGKSIGELNDTLYASFVLGAILEGIIFSVLIKIVYVFWKTPQKEK
>Mature_393_residues
SYPIETLSAFSIFVLLILFASPISSLTRIPIVVVEMILGAIAAHFFTFLNDSQEIHIVAEIGFLFLMFLCGLEVDIKSFA
KLGKPFLLQTLAYFCTLYGITCIVVFSAKISYVYIAAFPVMSLGMIVALIKDYGKDQPWLDLALKIGILGELVSIAALVI
IDGASRHGVGSELGRKLLMLGLFLLFVIFGFKIAKVIFWWIPQVRFLFLPNDDSNSQDLRFVFMLLFGFVLLMMFLEIKA
VLGAFLAGTILATFFKHKAELPEKLNHFGFGFFVPFFFVHVGSTLNLNAVFRDTQILYHALYLVIGMLTLRLISASIVFG
KYFKSAKFTLLFALSDSMPLTFLIATATLGKSIGELNDTLYASFVLGAILEGIIFSVLIKIVYVFWKTPQKEK

Specific function: Probable Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 43997; Mature: 43865

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SYPIETLSAFSIFVLLILFASPISSLTRIPIVVVEMILGAIAAHFFTFLNDSQEIHIVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]