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The map label for this gene is tolB

Identifier: 32265933

GI number: 32265933

Start: 416353

End: 417612

Strand: Direct

Name: tolB

Synonym: HH0434

Alternate gene names: 32265933

Gene position: 416353-417612 (Clockwise)

Preceding gene: 32265932

Following gene: 32265934

Centisome position: 23.14

GC content: 34.6

Gene sequence:

>1260_bases
ATGAGATTTATCGGTTTGGTTTTATTATTACTAAGTGTTAAATTATTTGGAATTGACGCAACATTGGAGATCGTCAAAAA
TACCAACAAGATTCCATATATCGTGGTTGAAAGATTAGATAGTGAAAATGCAGATTTTGGCGCAAAAGTACTTAAAATGC
TTGCAGCTGACTTAAAGGTAAGTGGGCATTTTCAAGTATATGATGGTAGCGTTAATAAAAACTCAGAGGTTGCATATAAA
GATTATGCAGATAAAAAAATTGATTTGCTTGCACAAATCAAAGTAAGTAAATCCTCAAATAGCCTTACAGGCACGATATC
GCTCTATGATATTAATACTTCCAAACGCATATATGTTAAAGATTACACCGAAAATGATGTAAAACGTTTTCCTTTCATCG
CTCATCGTATGTGTATTGATGTCAATAGTTATATCCAAGCCCCAAGTATTGAATGGATGCAACGTCTTGTTGTGCTTTCA
CAATACACAACTTCAGGTAATAGTGAGATTCTTATTGCTGATTATACCTTGACTTATCAAAAAGTTGTCGTTAAGGGTGG
GCTTAATATTTTTCCTAAATGGGTAGATTCTAAGCAAGAAAGCATTTATTACACAAAGTATCTTGATGTCCCCACAATCC
TTAAACATAATCTTACCACAGGACACATTGAACAACTCGTCGGTAGCGAAGGCATTGCTGTAGTTTCTGATGTAAGTAAA
AATGGAGAGAATCTTATCCTTAGCCTCTCTCCTACTGCTCTTTCCGATTTATATCTTTATAACACAAAAAGCAAAAATTT
GCGTAGACTCACAAACTATTCAGGTATTGATGTTGATGGAAAATTTGTCAATAATGAAAAAGAGATTATTTTTGTCTCTG
ATAGACTTGGTTACCCTAATATCTTTATGATGCGTCTTGATGGAGGCGGAACGGAACAAGTCGTGCTCCACGGACGCAAT
AACAGCGCAGTTACTTCAAATGGCAAATACGCAGTTTATACAAGTCGTGAAACAAACAATGAGTTTGGCGCTAATACTTT
TAATCTCTATCTTATTTCACTTGCTCCGGGTTCAAATTATATACGCCGACTTACGGCAAGTGGAAAAAATCAAATGCCCA
AATATTCAAATGATGGTGGAACAATTATGTATCTTAAGTATTACAAAGCACAAAGTGCTTTGGGAATAATTCGCATAGAT
TATAATACAAATTACTTTTTCCCTCTCATCAAAATGAAAATCCAAGCTTTTGATTGGTAA

Upstream 100 bases:

>100_bases
TCTCAAAACAATGCTTGAAGAATGCACACAAATGCACTTTCCACCTCACCCAAAGGGAACAAGGGAGATTGCTATAACTT
TTAAAAACTAAAGGAGTTGT

Downstream 100 bases:

>100_bases
GATATTTACTTTTATAGCGTAGAATCTTGCCATTTTAATTCTTAAAGGAGATGATGATGAAAAAATATATTGCAATGGGT
GTTTTAGCTGCGCTAATTTC

Product: translocation protein TolB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRFIGLVLLLLSVKLFGIDATLEIVKNTNKIPYIVVERLDSENADFGAKVLKMLAADLKVSGHFQVYDGSVNKNSEVAYK
DYADKKIDLLAQIKVSKSSNSLTGTISLYDINTSKRIYVKDYTENDVKRFPFIAHRMCIDVNSYIQAPSIEWMQRLVVLS
QYTTSGNSEILIADYTLTYQKVVVKGGLNIFPKWVDSKQESIYYTKYLDVPTILKHNLTTGHIEQLVGSEGIAVVSDVSK
NGENLILSLSPTALSDLYLYNTKSKNLRRLTNYSGIDVDGKFVNNEKEIIFVSDRLGYPNIFMMRLDGGGTEQVVLHGRN
NSAVTSNGKYAVYTSRETNNEFGANTFNLYLISLAPGSNYIRRLTASGKNQMPKYSNDGGTIMYLKYYKAQSALGIIRID
YNTNYFFPLIKMKIQAFDW

Sequences:

>Translated_419_residues
MRFIGLVLLLLSVKLFGIDATLEIVKNTNKIPYIVVERLDSENADFGAKVLKMLAADLKVSGHFQVYDGSVNKNSEVAYK
DYADKKIDLLAQIKVSKSSNSLTGTISLYDINTSKRIYVKDYTENDVKRFPFIAHRMCIDVNSYIQAPSIEWMQRLVVLS
QYTTSGNSEILIADYTLTYQKVVVKGGLNIFPKWVDSKQESIYYTKYLDVPTILKHNLTTGHIEQLVGSEGIAVVSDVSK
NGENLILSLSPTALSDLYLYNTKSKNLRRLTNYSGIDVDGKFVNNEKEIIFVSDRLGYPNIFMMRLDGGGTEQVVLHGRN
NSAVTSNGKYAVYTSRETNNEFGANTFNLYLISLAPGSNYIRRLTASGKNQMPKYSNDGGTIMYLKYYKAQSALGIIRID
YNTNYFFPLIKMKIQAFDW
>Mature_419_residues
MRFIGLVLLLLSVKLFGIDATLEIVKNTNKIPYIVVERLDSENADFGAKVLKMLAADLKVSGHFQVYDGSVNKNSEVAYK
DYADKKIDLLAQIKVSKSSNSLTGTISLYDINTSKRIYVKDYTENDVKRFPFIAHRMCIDVNSYIQAPSIEWMQRLVVLS
QYTTSGNSEILIADYTLTYQKVVVKGGLNIFPKWVDSKQESIYYTKYLDVPTILKHNLTTGHIEQLVGSEGIAVVSDVSK
NGENLILSLSPTALSDLYLYNTKSKNLRRLTNYSGIDVDGKFVNNEKEIIFVSDRLGYPNIFMMRLDGGGTEQVVLHGRN
NSAVTSNGKYAVYTSRETNNEFGANTFNLYLISLAPGSNYIRRLTASGKNQMPKYSNDGGTIMYLKYYKAQSALGIIRID
YNTNYFFPLIKMKIQAFDW

Specific function: Involved in the tonB-independent uptake of proteins

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TOLB_HELHP (Q7VJ16)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_859965.1
- ProteinModelPortal:   Q7VJ16
- GeneID:   1493488
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0434
- NMPDR:   fig|235279.1.peg.434
- HOGENOM:   HBG320885
- OMA:   LNIFPKW
- ProtClustDB:   PRK04043
- BioCyc:   HHEP235279:HH_0434-MONOMER
- HAMAP:   MF_00671
- InterPro:   IPR014167
- InterPro:   IPR007195
- InterPro:   IPR015943
- Gene3D:   G3DSA:3.40.50.10070
- Gene3D:   G3DSA:2.130.10.10

Pfam domain/function: PF04052 TolB_N; SSF52964 TolB_N

EC number: NA

Molecular weight: Translated: 47265; Mature: 47265

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFIGLVLLLLSVKLFGIDATLEIVKNTNKIPYIVVERLDSENADFGAKVLKMLAADLKV
CHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCEE
SGHFQVYDGSVNKNSEVAYKDYADKKIDLLAQIKVSKSSNSLTGTISLYDINTSKRIYVK
CCEEEEEECCCCCCCCEEECCCCCCCEEEEEEEEEECCCCCEEEEEEEEEECCCCEEEEE
DYTENDVKRFPFIAHRMCIDVNSYIQAPSIEWMQRLVVLSQYTTSGNSEILIADYTLTYQ
ECCCCCHHHCCHHHHHEEEEHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEE
KVVVKGGLNIFPKWVDSKQESIYYTKYLDVPTILKHNLTTGHIEQLVGSEGIAVVSDVSK
EEEEECCCEECCCCCCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHCCCCEEEEEECCC
NGENLILSLSPTALSDLYLYNTKSKNLRRLTNYSGIDVDGKFVNNEKEIIFVSDRLGYPN
CCCEEEEEECCCHHEEEEEEECCCCCHHHHCCCCCCCCCCEEECCCCEEEEEECCCCCCE
IFMMRLDGGGTEQVVLHGRNNSAVTSNGKYAVYTSRETNNEFGANTFNLYLISLAPGSNY
EEEEEECCCCCEEEEEECCCCCEEECCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCHH
IRRLTASGKNQMPKYSNDGGTIMYLKYYKAQSALGIIRIDYNTNYFFPLIKMKIQAFDW
HHEECCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEECCCCEEEEEEEEEEEEECC
>Mature Secondary Structure
MRFIGLVLLLLSVKLFGIDATLEIVKNTNKIPYIVVERLDSENADFGAKVLKMLAADLKV
CHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCEE
SGHFQVYDGSVNKNSEVAYKDYADKKIDLLAQIKVSKSSNSLTGTISLYDINTSKRIYVK
CCEEEEEECCCCCCCCEEECCCCCCCEEEEEEEEEECCCCCEEEEEEEEEECCCCEEEEE
DYTENDVKRFPFIAHRMCIDVNSYIQAPSIEWMQRLVVLSQYTTSGNSEILIADYTLTYQ
ECCCCCHHHCCHHHHHEEEEHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEE
KVVVKGGLNIFPKWVDSKQESIYYTKYLDVPTILKHNLTTGHIEQLVGSEGIAVVSDVSK
EEEEECCCEECCCCCCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHCCCCEEEEEECCC
NGENLILSLSPTALSDLYLYNTKSKNLRRLTNYSGIDVDGKFVNNEKEIIFVSDRLGYPN
CCCEEEEEECCCHHEEEEEEECCCCCHHHHCCCCCCCCCCEEECCCCEEEEEECCCCCCE
IFMMRLDGGGTEQVVLHGRNNSAVTSNGKYAVYTSRETNNEFGANTFNLYLISLAPGSNY
EEEEEECCCCCEEEEEECCCCCEEECCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCHH
IRRLTASGKNQMPKYSNDGGTIMYLKYYKAQSALGIIRIDYNTNYFFPLIKMKIQAFDW
HHEECCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEECCCCEEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12810954