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The map label for this gene is fmt

Identifier: 32265919

GI number: 32265919

Start: 405498

End: 406448

Strand: Direct

Name: fmt

Synonym: HH0420

Alternate gene names: 32265919

Gene position: 405498-406448 (Clockwise)

Preceding gene: 32265918

Following gene: 32265920

Centisome position: 22.54

GC content: 36.7

Gene sequence:

>951_bases
TTGCCCTGCAGATTCTCAAGGTATAAAGACGCTTATATGAAACTGATTCTCGCTGGAACACCTGCATTTGCATCGGCAAT
ATTTACACCCATAATAAAAAGCAAAATATTTGATATTCTTGCTCTTATCTGTCAGCCTGATAAGCCATTTGGTCGCAAAA
AAGAGCCCAAAGCCCCGCACACAAAAGAGAATTTTGCTTCAATGGGAATTGACATTTTACAACCCAATAAAATTGATGAA
ATATTTATTGCTCATATTCAAGCATTACAACCTGATGTGATACTTGTAGTAGCGTATGGGAAGATTTTACCTAAAGCTTT
TTTAGAGATTGCACCTTGTATTAATATTCACGCTTCAATTTTGCCTCTATGGCGCGGTGCAAGCCCTATTCAGCAGATGA
TACTTACTCAACCCCTATATTTTGGAGTAAGTGCTATAAAAATGAATGAAGAGCTTGATAAAGGAGCAATTTTGGGGCTA
CATTATGTGCCAAACACACAACAAAATATCACTCAACTCTCCGCTCAACTAAGTTGTGTGGGGGCAAAACTTGCATTGTA
TGTTCTCACACATTTCAAAGAAATTGAACCCTTAAATCAAATTAATGCAGATGCGAGTTATTGCACTAAAATTAAAAAAT
CTGATGGGTATGTGCAACTAGATGCGGCACTTAATGTATATTGTGCATATTTAGCATATTGCGAATGGCCCCATATTTTT
ATTAAAAGTATAAAAGGTTACACTCTCAAACTCTTTGATGTTGCTCTCATAGAATCTAGTGATTTACATAAAATGGGGGA
GATTCTAAGCATTGAAACTCAAAGTATTGTTGTAGGTTGTAAGCAGGGAAGTGTGCGCATTGGAACATTGCAACAAGAGG
GAAAAGAAAAGCTCAATGCCGCACTTTATTTACGTGGCAAAAGACTTAATGTAGGCGATATATTGTGCTAA

Upstream 100 bases:

>100_bases
TACTTCAACGCAAATGTATGATGTTTTTAAGCCACGGACGCAAACTTGATGTATTAAGAGATTTTCTTCTACATAATAAA
CAGAGTTCGGGCACACTTTT

Downstream 100 bases:

>100_bases
AATAAGGTATTATCAATGACTCATAATTCACCACAAGCTTTTTTTACAACTTCTTTTATCACTTTGCTCCAAGAACATAT
ATACCATTTTGATACATTAC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MPCRFSRYKDAYMKLILAGTPAFASAIFTPIIKSKIFDILALICQPDKPFGRKKEPKAPHTKENFASMGIDILQPNKIDE
IFIAHIQALQPDVILVVAYGKILPKAFLEIAPCINIHASILPLWRGASPIQQMILTQPLYFGVSAIKMNEELDKGAILGL
HYVPNTQQNITQLSAQLSCVGAKLALYVLTHFKEIEPLNQINADASYCTKIKKSDGYVQLDAALNVYCAYLAYCEWPHIF
IKSIKGYTLKLFDVALIESSDLHKMGEILSIETQSIVVGCKQGSVRIGTLQQEGKEKLNAALYLRGKRLNVGDILC

Sequences:

>Translated_316_residues
MPCRFSRYKDAYMKLILAGTPAFASAIFTPIIKSKIFDILALICQPDKPFGRKKEPKAPHTKENFASMGIDILQPNKIDE
IFIAHIQALQPDVILVVAYGKILPKAFLEIAPCINIHASILPLWRGASPIQQMILTQPLYFGVSAIKMNEELDKGAILGL
HYVPNTQQNITQLSAQLSCVGAKLALYVLTHFKEIEPLNQINADASYCTKIKKSDGYVQLDAALNVYCAYLAYCEWPHIF
IKSIKGYTLKLFDVALIESSDLHKMGEILSIETQSIVVGCKQGSVRIGTLQQEGKEKLNAALYLRGKRLNVGDILC
>Mature_315_residues
PCRFSRYKDAYMKLILAGTPAFASAIFTPIIKSKIFDILALICQPDKPFGRKKEPKAPHTKENFASMGIDILQPNKIDEI
FIAHIQALQPDVILVVAYGKILPKAFLEIAPCINIHASILPLWRGASPIQQMILTQPLYFGVSAIKMNEELDKGAILGLH
YVPNTQQNITQLSAQLSCVGAKLALYVLTHFKEIEPLNQINADASYCTKIKKSDGYVQLDAALNVYCAYLAYCEWPHIFI
KSIKGYTLKLFDVALIESSDLHKMGEILSIETQSIVVGCKQGSVRIGTLQQEGKEKLNAALYLRGKRLNVGDILC

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Escherichia coli, GI1789683, Length=307, Percent_Identity=30.2931596091205, Blast_Score=127, Evalue=7e-31,
Organism=Drosophila melanogaster, GI28571984, Length=230, Percent_Identity=27.8260869565217, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45550868, Length=230, Percent_Identity=27.8260869565217, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 35112; Mature: 34981

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCRFSRYKDAYMKLILAGTPAFASAIFTPIIKSKIFDILALICQPDKPFGRKKEPKAPH
CCCCCHHHHHHHHEEHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
TKENFASMGIDILQPNKIDEIFIAHIQALQPDVILVVAYGKILPKAFLEIAPCINIHASI
CHHHHHHCCCEEECCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCHHCCHHHH
LPLWRGASPIQQMILTQPLYFGVSAIKMNEELDKGAILGLHYVPNTQQNITQLSAQLSCV
HHHHCCCHHHHHHHHHCHHHHCHHHEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
GAKLALYVLTHFKEIEPLNQINADASYCTKIKKSDGYVQLDAALNVYCAYLAYCEWPHIF
HHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCHHHH
IKSIKGYTLKLFDVALIESSDLHKMGEILSIETQSIVVGCKQGSVRIGTLQQEGKEKLNA
HHHCCCCEEEEEEEEEECCCCHHHHHHHHEEEEEEEEEEECCCCEEEECCHHHHHHHHCE
ALYLRGKRLNVGDILC
EEEEECCCCCCCCCCC
>Mature Secondary Structure 
PCRFSRYKDAYMKLILAGTPAFASAIFTPIIKSKIFDILALICQPDKPFGRKKEPKAPH
CCCCHHHHHHHHEEHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
TKENFASMGIDILQPNKIDEIFIAHIQALQPDVILVVAYGKILPKAFLEIAPCINIHASI
CHHHHHHCCCEEECCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCHHCCHHHH
LPLWRGASPIQQMILTQPLYFGVSAIKMNEELDKGAILGLHYVPNTQQNITQLSAQLSCV
HHHHCCCHHHHHHHHHCHHHHCHHHEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
GAKLALYVLTHFKEIEPLNQINADASYCTKIKKSDGYVQLDAALNVYCAYLAYCEWPHIF
HHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCHHHH
IKSIKGYTLKLFDVALIESSDLHKMGEILSIETQSIVVGCKQGSVRIGTLQQEGKEKLNA
HHHCCCCEEEEEEEEEECCCCHHHHHHHHEEEEEEEEEEECCCCEEEECCHHHHHHHHCE
ALYLRGKRLNVGDILC
EEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA