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The map label for this gene is ureH

Identifier: 32265912

GI number: 32265912

Start: 396730

End: 397410

Strand: Direct

Name: ureH

Synonym: HH0413

Alternate gene names: 32265912

Gene position: 396730-397410 (Clockwise)

Preceding gene: 32265911

Following gene: 32265917

Centisome position: 22.05

GC content: 32.31

Gene sequence:

>681_bases
ATGTTTTTTACACCTCCCTTAAAGATAATAAGCCCACTAGAAGATGAGGATATAGCCGAAATTATGCTTATATCAGTTTC
AGCTGGGCTACTTAAAGATGATTGCCAAGATATTCAAATACACATTGGCAAAGAAAGTAAAATTCGTCTCATCTCGCAAA
GTTATGAAAAAATACACGATACACAAGATGGCTACGCAAGCAAGCATACTCAAATTACAATAGAAGAAAATGCCTTTTTA
GATTATGCACCCCTGCCTATATTACCCTTTAAAGATTCTTCATTCAAAAATACTACTGATATTTATCTTAGCAAAAATGC
TAGACTTCATTACAGCGAGATAATATGCGCAGGTAGAGTAGCTATGGGAGAAATATTTGATTTTTCAGAATTAAGCTCAA
GACTTCGCATATATAAAGAAAATCATTTAGTATTTTTTGAAAATATGAATCTTAAACCTGCACAAATGGCTATGCAAAAT
ATTTGCCTCTTTGATAAATATACTCACGCTTTGAGTATGGTAATATTTGATGACTTAATAGAGGTTCAAGCCTTAGAGCA
AAAAATCAAAAACAGCTCCTTAAATGTTGGCATAAGCACAAATAATGGAGGTATTATCATCAAAGCATTAGATAATCAAA
GCGAGAGATTGCTCCAATTCAAAAAAGACTTAGCTTTATAA

Upstream 100 bases:

>100_bases
AATATGCACTTTTGGAAGATATATGAGTAGCTTTGCACAAAAGAGTATCTTAAAACTCAAAACAAAAAGAGGTTTAAATG
GCAAAAATATCATTGAGGAG

Downstream 100 bases:

>100_bases
TCTTAGGTTATATCACATAATTTTCCATCTTCTATCACCTTGAGATTCCCACATAATTTTTGAGCTATATATTTATCGTG
TGTGATAAGCAAAATTGCGC

Product: urease accessory protein UreH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MFFTPPLKIISPLEDEDIAEIMLISVSAGLLKDDCQDIQIHIGKESKIRLISQSYEKIHDTQDGYASKHTQITIEENAFL
DYAPLPILPFKDSSFKNTTDIYLSKNARLHYSEIICAGRVAMGEIFDFSELSSRLRIYKENHLVFFENMNLKPAQMAMQN
ICLFDKYTHALSMVIFDDLIEVQALEQKIKNSSLNVGISTNNGGIIIKALDNQSERLLQFKKDLAL

Sequences:

>Translated_226_residues
MFFTPPLKIISPLEDEDIAEIMLISVSAGLLKDDCQDIQIHIGKESKIRLISQSYEKIHDTQDGYASKHTQITIEENAFL
DYAPLPILPFKDSSFKNTTDIYLSKNARLHYSEIICAGRVAMGEIFDFSELSSRLRIYKENHLVFFENMNLKPAQMAMQN
ICLFDKYTHALSMVIFDDLIEVQALEQKIKNSSLNVGISTNNGGIIIKALDNQSERLLQFKKDLAL
>Mature_226_residues
MFFTPPLKIISPLEDEDIAEIMLISVSAGLLKDDCQDIQIHIGKESKIRLISQSYEKIHDTQDGYASKHTQITIEENAFL
DYAPLPILPFKDSSFKNTTDIYLSKNARLHYSEIICAGRVAMGEIFDFSELSSRLRIYKENHLVFFENMNLKPAQMAMQN
ICLFDKYTHALSMVIFDDLIEVQALEQKIKNSSLNVGISTNNGGIIIKALDNQSERLLQFKKDLAL

Specific function: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter

COG id: COG0829

COG function: function code O; Urease accessory protein UreH

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREH_HELHP (Q7VJ35)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_859944.1
- GeneID:   1493467
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0413
- HOGENOM:   HBG500138
- OMA:   CKLRITS
- ProtClustDB:   CLSK495846
- BioCyc:   HHEP235279:HH_0413-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01384
- InterPro:   IPR002669

Pfam domain/function: PF01774 UreD

EC number: NA

Molecular weight: Translated: 25724; Mature: 25724

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFTPPLKIISPLEDEDIAEIMLISVSAGLLKDDCQDIQIHIGKESKIRLISQSYEKIHD
CCCCCCHHHHCCCCCCCHHHEEEEECCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHC
TQDGYASKHTQITIEENAFLDYAPLPILPFKDSSFKNTTDIYLSKNARLHYSEIICAGRV
CCCCCCCCCEEEEEECCCEEEECCCCEEECCCCCCCCCEEEEEECCCEEEHHHHEECCCH
AMGEIFDFSELSSRLRIYKENHLVFFENMNLKPAQMAMQNICLFDKYTHALSMVIFDDLI
HHHHHCCHHHHHHHHEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVQALEQKIKNSSLNVGISTNNGGIIIKALDNQSERLLQFKKDLAL
HHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MFFTPPLKIISPLEDEDIAEIMLISVSAGLLKDDCQDIQIHIGKESKIRLISQSYEKIHD
CCCCCCHHHHCCCCCCCHHHEEEEECCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHC
TQDGYASKHTQITIEENAFLDYAPLPILPFKDSSFKNTTDIYLSKNARLHYSEIICAGRV
CCCCCCCCCEEEEEECCCEEEECCCCEEECCCCCCCCCEEEEEECCCEEEHHHHEECCCH
AMGEIFDFSELSSRLRIYKENHLVFFENMNLKPAQMAMQNICLFDKYTHALSMVIFDDLI
HHHHHCCHHHHHHHHEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVQALEQKIKNSSLNVGISTNNGGIIIKALDNQSERLLQFKKDLAL
HHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954