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The map label for this gene is ureG

Identifier: 32265911

GI number: 32265911

Start: 396053

End: 396655

Strand: Direct

Name: ureG

Synonym: HH0412

Alternate gene names: 32265911

Gene position: 396053-396655 (Clockwise)

Preceding gene: 32265910

Following gene: 32265912

Centisome position: 22.01

GC content: 38.14

Gene sequence:

>603_bases
ATGGTAAAAATAGGTATATGCGGACCAGTAGGAAGTGGCAAAACTGCCCTTATAGAATCTCTTACACGCAAGATGAATGA
GCAATACTCTCTTGCTGTCATCACTAATGATATTTATACACAAGAAGATGCGGAGTTTATGAGTAAAAATTCCGTGCTAC
CAAGTGAGCGAATCATAGGAGTGGAAACGGGTGGTTGCCCTCATACAGCAATCAGAGAAGATGCTTCTATGAATCTTGAA
GCAGTGGAAGAAATGCAAGAGAGATTTCCAGATATTGAGATTCTCTTTATAGAAAGCGGTGGTGATAATCTCTCTGCCAC
ATTTAGCCCAGAATTAGCAGATTTTACAATTTTTGTTATTGATGTGGCACAAGGGGATAAAATCCCACGAAAAGGCGGAC
CGGGCATTATGCGTTCAGATTTGCTCATTATCAATAAAATTGATTTAGCTCCTTATGTGGGTGCAAATTTAAGCATAATG
GAAAGAGATGCCAAAAAAATGCGTGAAGATAAGCCATTTTTATTTACAAATATTCGTGCTAAAGAGGGAATTGATGCCGT
GGTGGAATGGATAAAAAAATATGCACTTTTGGAAGATATATGA

Upstream 100 bases:

>100_bases
ACAAAGCAAGATTTATGCAATAACGCTATTGCTAGCGAGATTAAAGCAATGCAACATCAATATTTACCCACAAGATTATA
TATGTCATAAAGGAGAAAAA

Downstream 100 bases:

>100_bases
GTAGCTTTGCACAAAAGAGTATCTTAAAACTCAAAACAAAAAGAGGTTTAAATGGCAAAAATATCATTGAGGAGATGTTT
TTTACACCTCCCTTAAAGAT

Product: urease/hydrogenase-associated GTPase UreG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MVKIGICGPVGSGKTALIESLTRKMNEQYSLAVITNDIYTQEDAEFMSKNSVLPSERIIGVETGGCPHTAIREDASMNLE
AVEEMQERFPDIEILFIESGGDNLSATFSPELADFTIFVIDVAQGDKIPRKGGPGIMRSDLLIINKIDLAPYVGANLSIM
ERDAKKMREDKPFLFTNIRAKEGIDAVVEWIKKYALLEDI

Sequences:

>Translated_200_residues
MVKIGICGPVGSGKTALIESLTRKMNEQYSLAVITNDIYTQEDAEFMSKNSVLPSERIIGVETGGCPHTAIREDASMNLE
AVEEMQERFPDIEILFIESGGDNLSATFSPELADFTIFVIDVAQGDKIPRKGGPGIMRSDLLIINKIDLAPYVGANLSIM
ERDAKKMREDKPFLFTNIRAKEGIDAVVEWIKKYALLEDI
>Mature_200_residues
MVKIGICGPVGSGKTALIESLTRKMNEQYSLAVITNDIYTQEDAEFMSKNSVLPSERIIGVETGGCPHTAIREDASMNLE
AVEEMQERFPDIEILFIESGGDNLSATFSPELADFTIFVIDVAQGDKIPRKGGPGIMRSDLLIINKIDLAPYVGANLSIM
ERDAKKMREDKPFLFTNIRAKEGIDAVVEWIKKYALLEDI

Specific function: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by ureG

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureG family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREG_HELHP (Q93PJ0)

Other databases:

- EMBL:   AF332656
- EMBL:   AE017125
- RefSeq:   NP_859943.1
- ProteinModelPortal:   Q93PJ0
- SMR:   Q93PJ0
- GeneID:   1493466
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0412
- NMPDR:   fig|235279.1.peg.412
- HOGENOM:   HBG364734
- OMA:   RFPDSDV
- ProtClustDB:   CLSK872265
- BioCyc:   HHEP235279:HH_0412-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01389
- InterPro:   IPR003495
- InterPro:   IPR012202
- InterPro:   IPR004400
- PIRSF:   PIRSF005624
- TIGRFAMs:   TIGR00101

Pfam domain/function: PF02492 cobW

EC number: NA

Molecular weight: Translated: 22131; Mature: 22131

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIGICGPVGSGKTALIESLTRKMNEQYSLAVITNDIYTQEDAEFMSKNSVLPSERIIG
CEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCCCHHEEE
VETGGCPHTAIREDASMNLEAVEEMQERFPDIEILFIESGGDNLSATFSPELADFTIFVI
EECCCCCCHHHCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCEEEEEE
DVAQGDKIPRKGGPGIMRSDLLIINKIDLAPYVGANLSIMERDAKKMREDKPFLFTNIRA
EECCCCCCCCCCCCCCEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
KEGIDAVVEWIKKYALLEDI
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKIGICGPVGSGKTALIESLTRKMNEQYSLAVITNDIYTQEDAEFMSKNSVLPSERIIG
CEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCCCHHEEE
VETGGCPHTAIREDASMNLEAVEEMQERFPDIEILFIESGGDNLSATFSPELADFTIFVI
EECCCCCCHHHCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCEEEEEE
DVAQGDKIPRKGGPGIMRSDLLIINKIDLAPYVGANLSIMERDAKKMREDKPFLFTNIRA
EECCCCCCCCCCCCCCEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
KEGIDAVVEWIKKYALLEDI
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11500473; 12810954