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The map label for this gene is surE

Identifier: 32265834

GI number: 32265834

Start: 330594

End: 331388

Strand: Direct

Name: surE

Synonym: HH0335

Alternate gene names: 32265834

Gene position: 330594-331388 (Clockwise)

Preceding gene: 32265833

Following gene: 32265835

Centisome position: 18.38

GC content: 40.63

Gene sequence:

>795_bases
ATGAAGCGCATTCTCCTTACCAATGATGATGGCTTTGACTCAAGCGGTCTTCTTGCACTCAAAGATGCCCTCAAAGATAT
AGCACACGTGATGGTTGTCGCTCCAGCAAGTGAAAAATCAGCGTGTGGGCACGGACTAACACTCACGCGCCCACTTAGTT
TTGTGCAGCTTGATGATGATTTTTATAAACTTGAAGATGGCACGCCCAGTGATTGTGTGTATCTTGCACTCAATACGCTT
TATAAAGCATCGTGCAAACCCGATTTAGTTATTTCGGGCATTAATCTTGGCTCAAATATGGGAGAAGATATTACTTATTC
AGGAACAGCTGCAGGCGCTATGGAAGGGTGCATACAAGGTGTGCCTTCTATTGCTATTTCACAGCTTATGCCAGATAAAA
ATTGCTCAAAACATTTTGACTTTTCCCTTGCCAAAGAATGTATTTATAAAATCACTCAACTTATTTTTGCCAAAGGATTC
CCTTTGGGAGAGCGCAAATTTCTTAATATCAATATCCCTCACATTAAGCCTAAAGAATGCAAAGGTTACAAAATCACGCA
AATGGGTTATAGAATCTACGCTGATAATGCACATTTACACCGCAATCCACGAGGACAAGAATATTATTGGCTGGGGCTAC
ACCCTTTAGAATGGGAAGAACGCAACGATATGCCTCATAGTTATGGTTCTGACTTTAAAGCAACGCACGAACATTATGTC
TCTATCACACCTATCAAGCTTGATATGACAAGCTATGAGGATAGTTCATCTCTTTGCGAATGGATACAATTATGA

Upstream 100 bases:

>100_bases
CTCGTATGAAAGAGCAGATTCAAAAAGAACTCCAAACATTTGATGAAGCCATTTATGTTCATTTGACTACTCTTTTGCAA
GATTATTTCAAGGATATTGA

Downstream 100 bases:

>100_bases
ATGAACTTGTTGATGAAAATACAATAATTGATAGATACACGCGTTCGCGCATTATTTTTGGCGAAAACTTTGAGCGCATA
CAAAATACAAAAGTAGTTGT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKRILLTNDDGFDSSGLLALKDALKDIAHVMVVAPASEKSACGHGLTLTRPLSFVQLDDDFYKLEDGTPSDCVYLALNTL
YKASCKPDLVISGINLGSNMGEDITYSGTAAGAMEGCIQGVPSIAISQLMPDKNCSKHFDFSLAKECIYKITQLIFAKGF
PLGERKFLNINIPHIKPKECKGYKITQMGYRIYADNAHLHRNPRGQEYYWLGLHPLEWEERNDMPHSYGSDFKATHEHYV
SITPIKLDMTSYEDSSSLCEWIQL

Sequences:

>Translated_264_residues
MKRILLTNDDGFDSSGLLALKDALKDIAHVMVVAPASEKSACGHGLTLTRPLSFVQLDDDFYKLEDGTPSDCVYLALNTL
YKASCKPDLVISGINLGSNMGEDITYSGTAAGAMEGCIQGVPSIAISQLMPDKNCSKHFDFSLAKECIYKITQLIFAKGF
PLGERKFLNINIPHIKPKECKGYKITQMGYRIYADNAHLHRNPRGQEYYWLGLHPLEWEERNDMPHSYGSDFKATHEHYV
SITPIKLDMTSYEDSSSLCEWIQL
>Mature_264_residues
MKRILLTNDDGFDSSGLLALKDALKDIAHVMVVAPASEKSACGHGLTLTRPLSFVQLDDDFYKLEDGTPSDCVYLALNTL
YKASCKPDLVISGINLGSNMGEDITYSGTAAGAMEGCIQGVPSIAISQLMPDKNCSKHFDFSLAKECIYKITQLIFAKGF
PLGERKFLNINIPHIKPKECKGYKITQMGYRIYADNAHLHRNPRGQEYYWLGLHPLEWEERNDMPHSYGSDFKATHEHYV
SITPIKLDMTSYEDSSSLCEWIQL

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=261, Percent_Identity=37.1647509578544, Blast_Score=174, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_HELHP (Q7VJA8)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_859866.1
- ProteinModelPortal:   Q7VJA8
- SMR:   Q7VJA8
- GeneID:   1493389
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0335
- NMPDR:   fig|235279.1.peg.335
- HOGENOM:   HBG600532
- OMA:   KHTASAG
- ProtClustDB:   PRK00346
- BioCyc:   HHEP235279:HH_0335-MONOMER
- BRENDA:   3.1.3.5
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 29538; Mature: 29538

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILLTNDDGFDSSGLLALKDALKDIAHVMVVAPASEKSACGHGLTLTRPLSFVQLDDD
CCEEEEECCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEECCEEEEEECCC
FYKLEDGTPSDCVYLALNTLYKASCKPDLVISGINLGSNMGEDITYSGTAAGAMEGCIQG
EEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEECCCCHHHHHHHHHC
VPSIAISQLMPDKNCSKHFDFSLAKECIYKITQLIFAKGFPLGERKFLNINIPHIKPKEC
CCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCC
KGYKITQMGYRIYADNAHLHRNPRGQEYYWLGLHPLEWEERNDMPHSYGSDFKATHEHYV
CCEEEEECCEEEEECCCEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEE
SITPIKLDMTSYEDSSSLCEWIQL
EEEEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MKRILLTNDDGFDSSGLLALKDALKDIAHVMVVAPASEKSACGHGLTLTRPLSFVQLDDD
CCEEEEECCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEECCEEEEEECCC
FYKLEDGTPSDCVYLALNTLYKASCKPDLVISGINLGSNMGEDITYSGTAAGAMEGCIQG
EEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEECCCCHHHHHHHHHC
VPSIAISQLMPDKNCSKHFDFSLAKECIYKITQLIFAKGFPLGERKFLNINIPHIKPKEC
CCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCC
KGYKITQMGYRIYADNAHLHRNPRGQEYYWLGLHPLEWEERNDMPHSYGSDFKATHEHYV
CCEEEEECCEEEEECCCEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEE
SITPIKLDMTSYEDSSSLCEWIQL
EEEEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954