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The map label for this gene is mrp

Identifier: 30995435

GI number: 30995435

Start: 1354058

End: 1355170

Strand: Direct

Name: mrp

Synonym: HI1277

Alternate gene names: 30995435

Gene position: 1354058-1355170 (Clockwise)

Preceding gene: 16273189

Following gene: 16273194

Centisome position: 73.99

GC content: 41.69

Gene sequence:

>1113_bases
ATGGCAACCTACTTTTCTGATAATTTGACTGCCGACCAGCAAAACCAAGTTCAGCAGATTATTCAACAATTTCAGCATCC
AACCCTGCAAAAGGATCTGATTGTGCTTAATACTTTGAAAAAAGTGGAAAAGGGCGGCGATACTTTACGCATTGAATTGC
AATTACCTTTTGCATGGAATTCTGGTGCAGAACAGTTAAAACAAGCGGTTTCAGATGCGTTGTTGAAAGCAACAGATTGT
AAATTAATTAAATGGGCGGTGGCTTATCAAATCGCCACACTTAAACGTGCAAACAATCAACCGGCAGTAAAAGGTGTGAA
AAACATTATTGCTGTGAGTTCTGGTAAAGGCGGCGTAGGGAAATCATCGGTTTCTGTTAATCTAGCTTTAGCATTACAAG
CACAAGGCGCACGTGTTGGAATTTTAGATGCGGATATTTATGGCCCTTCTATTCCTCATATGTTAGGCGCAGCGGATCAA
CGCCCGACTTCGCCAGATAATCAACACATCACCCCAATTAAAGCACATGGTTTATCTGCAAATTCCATTGGCTTTTTAAT
GAATGAAGATAGCGCAACAATTTGGCGTGGCCCAATGGCGAGCAGTGCATTAAGCCAATTATTAAATGAAACCCTATGGG
ATAGTTTAGATTATCTTGTTATCGATATGCCTCCGGGCACTGGCGATATTCAACTTACCTTATCACAACAAATCCCTGTG
ACTGGTGCAGTGGTTGTGACAACTCCACAAGATATTGCTTTGCTTGACGCAGTGAAAGGTATTTCAATGTTTGAGCGAGT
ATCCGTACCAGTGTTAGGCATTGTGGAAAATATGTCGATGCATATTTGTAGCGAGTGCGGTCATCACGAAGCGATTTTTG
GCACAGGCGGTGCAGAGAAAATGGCGGAAAAATACAATGTGAAAGTATTAGCTCAACTTCCTCTGCATATTCGTATCCGT
GAAGATTTAGATGCAGGCAACCCGACCGTTGTGCGAGTGCCTGAAAATGAAATTTCACAAGCGTTCTTACAACTTGCCGA
AAAAGTCTCTACAGAACTTTACTGGCAAGGTTCCGTAATCCCAAGCGAGATTTTATTTAAAGAAGTGAAATAA

Upstream 100 bases:

>100_bases
TAGGGGATTTTTTCTAGTTTGAAAAACTTTAACTTAACATACCGCACTTTCCGTGATTAAATATGCCCGACAAATTTACT
CTACTAAACAGGAAGTTATT

Downstream 100 bases:

>100_bases
TCAAAAAAGATAGGGCTGCATGTGCAGCCCTTTTTTAATGGGATTTTTACCCCACCCATTTCACCACTTCATCCAATCCT
TTACGGGATTTTTTCGCAAT

Product: putative ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MATYFSDNLTADQQNQVQQIIQQFQHPTLQKDLIVLNTLKKVEKGGDTLRIELQLPFAWNSGAEQLKQAVSDALLKATDC
KLIKWAVAYQIATLKRANNQPAVKGVKNIIAVSSGKGGVGKSSVSVNLALALQAQGARVGILDADIYGPSIPHMLGAADQ
RPTSPDNQHITPIKAHGLSANSIGFLMNEDSATIWRGPMASSALSQLLNETLWDSLDYLVIDMPPGTGDIQLTLSQQIPV
TGAVVVTTPQDIALLDAVKGISMFERVSVPVLGIVENMSMHICSECGHHEAIFGTGGAEKMAEKYNVKVLAQLPLHIRIR
EDLDAGNPTVVRVPENEISQAFLQLAEKVSTELYWQGSVIPSEILFKEVK

Sequences:

>Translated_370_residues
MATYFSDNLTADQQNQVQQIIQQFQHPTLQKDLIVLNTLKKVEKGGDTLRIELQLPFAWNSGAEQLKQAVSDALLKATDC
KLIKWAVAYQIATLKRANNQPAVKGVKNIIAVSSGKGGVGKSSVSVNLALALQAQGARVGILDADIYGPSIPHMLGAADQ
RPTSPDNQHITPIKAHGLSANSIGFLMNEDSATIWRGPMASSALSQLLNETLWDSLDYLVIDMPPGTGDIQLTLSQQIPV
TGAVVVTTPQDIALLDAVKGISMFERVSVPVLGIVENMSMHICSECGHHEAIFGTGGAEKMAEKYNVKVLAQLPLHIRIR
EDLDAGNPTVVRVPENEISQAFLQLAEKVSTELYWQGSVIPSEILFKEVK
>Mature_369_residues
ATYFSDNLTADQQNQVQQIIQQFQHPTLQKDLIVLNTLKKVEKGGDTLRIELQLPFAWNSGAEQLKQAVSDALLKATDCK
LIKWAVAYQIATLKRANNQPAVKGVKNIIAVSSGKGGVGKSSVSVNLALALQAQGARVGILDADIYGPSIPHMLGAADQR
PTSPDNQHITPIKAHGLSANSIGFLMNEDSATIWRGPMASSALSQLLNETLWDSLDYLVIDMPPGTGDIQLTLSQQIPVT
GAVVVTTPQDIALLDAVKGISMFERVSVPVLGIVENMSMHICSECGHHEAIFGTGGAEKMAEKYNVKVLAQLPLHIRIRE
DLDAGNPTVVRVPENEISQAFLQLAEKVSTELYWQGSVIPSEILFKEVK

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family

Homologues:

Organism=Homo sapiens, GI157384956, Length=257, Percent_Identity=49.8054474708171, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI6912540, Length=254, Percent_Identity=38.5826771653543, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI118572611, Length=255, Percent_Identity=36.4705882352941, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI87082045, Length=353, Percent_Identity=66.0056657223796, Blast_Score=484, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI25143050, Length=257, Percent_Identity=41.2451361867704, Blast_Score=187, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6322188, Length=276, Percent_Identity=35.5072463768116, Blast_Score=182, Evalue=8e-47,
Organism=Saccharomyces cerevisiae, GI6321347, Length=253, Percent_Identity=39.5256916996047, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI221511043, Length=251, Percent_Identity=42.6294820717131, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24667611, Length=257, Percent_Identity=39.6887159533074, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI19921440, Length=240, Percent_Identity=37.9166666666667, Blast_Score=135, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRP_HAEIN (P45135)

Other databases:

- EMBL:   L42023
- PIR:   A64114
- RefSeq:   NP_439430.2
- ProteinModelPortal:   P45135
- SMR:   P45135
- GeneID:   950197
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1277
- NMPDR:   fig|71421.1.peg.1219
- TIGR:   HI_1277
- HOGENOM:   HBG586485
- OMA:   HIRIRED
- ProtClustDB:   PRK11670
- BioCyc:   HINF71421:HI_1277-MONOMER
- InterPro:   IPR019591
- InterPro:   IPR000808

Pfam domain/function: PF10609 ParA

EC number: NA

Molecular weight: Translated: 40047; Mature: 39915

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYFSDNLTADQQNQVQQIIQQFQHPTLQKDLIVLNTLKKVEKGGDTLRIELQLPFAWN
CCEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
SGAEQLKQAVSDALLKATDCKLIKWAVAYQIATLKRANNQPAVKGVKNIIAVSSGKGGVG
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCCCCC
KSSVSVNLALALQAQGARVGILDADIYGPSIPHMLGAADQRPTSPDNQHITPIKAHGLSA
CCCEEEEEEEEEEECCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCCCC
NSIGFLMNEDSATIWRGPMASSALSQLLNETLWDSLDYLVIDMPPGTGDIQLTLSQQIPV
CCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCC
TGAVVVTTPQDIALLDAVKGISMFERVSVPVLGIVENMSMHICSECGHHEAIFGTGGAEK
EEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
MAEKYNVKVLAQLPLHIRIREDLDAGNPTVVRVPENEISQAFLQLAEKVSTELYWQGSVI
HHHHCCEEEEEECCEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHCCEEEEECCCC
PSEILFKEVK
HHHHHHHCCC
>Mature Secondary Structure 
ATYFSDNLTADQQNQVQQIIQQFQHPTLQKDLIVLNTLKKVEKGGDTLRIELQLPFAWN
CEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
SGAEQLKQAVSDALLKATDCKLIKWAVAYQIATLKRANNQPAVKGVKNIIAVSSGKGGVG
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCCCCC
KSSVSVNLALALQAQGARVGILDADIYGPSIPHMLGAADQRPTSPDNQHITPIKAHGLSA
CCCEEEEEEEEEEECCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCCCC
NSIGFLMNEDSATIWRGPMASSALSQLLNETLWDSLDYLVIDMPPGTGDIQLTLSQQIPV
CCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCC
TGAVVVTTPQDIALLDAVKGISMFERVSVPVLGIVENMSMHICSECGHHEAIFGTGGAEK
EEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
MAEKYNVKVLAQLPLHIRIREDLDAGNPTVVRVPENEISQAFLQLAEKVSTELYWQGSVI
HHHHCCEEEEEECCEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHCCEEEEECCCC
PSEILFKEVK
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800