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The map label for this gene is yecK

Identifier: 30995392

GI number: 30995392

Start: 687976

End: 689076

Strand: Reverse

Name: yecK

Synonym: HI0644

Alternate gene names: 30995392

Gene position: 689076-687976 (Counterclockwise)

Preceding gene: 16272588

Following gene: 16272586

Centisome position: 37.65

GC content: 39.15

Gene sequence:

>1101_bases
ATGTCAAAAATGAAAAAAATAGTAACCGCACTTTGTTTAGTCGGTGTCGGGGTGGGAGCATTATGGGGTTCTCAGTGGAT
AATGCACAAAACGAGTACACCAGAGTTTTGTGCTAGTTGTCATTCAATGAGTTATCCACAACAGGAGTGGGAAGGTTCTA
GCCATTTTGCTAATGCAAAAGGGGTTAGAGCACAATGTTCAGATTGTCATATTCCAAAAGAAGGTTGGCATTATGTCAAG
GCTAAATTTATTGCTTTAAAAGACTTGTGGTATGAAGCACAAGGTAAGATTGAGAATAAAGAAAAATATGAAGCTCATCG
TGCAGAAATGGCACAACGAGTGTGGAAGGATATGAAAGCCAATGATTCAGAAACCTGTCGTAGCTGTCACAGTTTTGATG
CAATGGAGCTTTCAAAACAAACTAAATTAGCAAAACAAACTCATACGGAGGCGCAAACAAACGGTCAAACTTGTATTGAT
TGTCACAAGGGCATTGTTCACTTCCTACCTGAAGTGCATGGCGATCAAAATACACAAAAATCCTCTGCAGTACAAGGTGG
TACTCTCTCTGATGGCTCAGCTATTTTTGCCACTGAAATGGTAAAAGCGACCAATGATAAAGGAAATGAGGTTCGCCTAA
TGCCTTATGCAGAATTAATGCAATGGAAAGTGGATGGTGATCAAATTCAAGGCACTTTACATGGTTGGCAACAAGTGGGG
GCTGAAGCAGTTGTGTATCAAGAATTAGGTAAACGTATCACGCTTGCTTTAATGGACGAAGATGCACGTAATCATGTTCA
AGTATTAAAAATAGTTCATGATGCAGTAACAGATTCTGATTGGAAAGAAATCAGTGTTGCGGTGAATGTCGCAAAAGAAA
AAATGACATCAGATTTAACCACGCTTAATCAATACGGTAATCAGTTAAACCAAACTCAATGTAGTGGTTGTCACGCAGCA
ATTGGTGCAGATCATTACACGGCTAACCAATGGATTGGTGTGGTGAATTCTATGAAAGACCGTACATCAATGAAAAAAGA
TGAAGTACGTGCATTAACTATTTATCTGCAACGCAATGCCAAAGATATGGCAAAACAATAA

Upstream 100 bases:

>100_bases
TTTCTTGAGAAATATCATAGTTTTTGATTTACAAAACCTCTACAATCAACCCTAACTATAAGTAGTTAGGGTTGTTTTTT
ATTATTTTATTGGAGTGGCT

Downstream 100 bases:

>100_bases
TGAATGAATTAACTATCTAAAACGAGGCTGAAATGAAAAAGAATAACGTAAATGAACAACGTCGTGATTTTCTGAAAAAA
ACATCTTTAGGCGTGGCTGG

Product: cytochrome C-like protein

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSKMKKIVTALCLVGVGVGALWGSQWIMHKTSTPEFCASCHSMSYPQQEWEGSSHFANAKGVRAQCSDCHIPKEGWHYVK
AKFIALKDLWYEAQGKIENKEKYEAHRAEMAQRVWKDMKANDSETCRSCHSFDAMELSKQTKLAKQTHTEAQTNGQTCID
CHKGIVHFLPEVHGDQNTQKSSAVQGGTLSDGSAIFATEMVKATNDKGNEVRLMPYAELMQWKVDGDQIQGTLHGWQQVG
AEAVVYQELGKRITLALMDEDARNHVQVLKIVHDAVTDSDWKEISVAVNVAKEKMTSDLTTLNQYGNQLNQTQCSGCHAA
IGADHYTANQWIGVVNSMKDRTSMKKDEVRALTIYLQRNAKDMAKQ

Sequences:

>Translated_366_residues
MSKMKKIVTALCLVGVGVGALWGSQWIMHKTSTPEFCASCHSMSYPQQEWEGSSHFANAKGVRAQCSDCHIPKEGWHYVK
AKFIALKDLWYEAQGKIENKEKYEAHRAEMAQRVWKDMKANDSETCRSCHSFDAMELSKQTKLAKQTHTEAQTNGQTCID
CHKGIVHFLPEVHGDQNTQKSSAVQGGTLSDGSAIFATEMVKATNDKGNEVRLMPYAELMQWKVDGDQIQGTLHGWQQVG
AEAVVYQELGKRITLALMDEDARNHVQVLKIVHDAVTDSDWKEISVAVNVAKEKMTSDLTTLNQYGNQLNQTQCSGCHAA
IGADHYTANQWIGVVNSMKDRTSMKKDEVRALTIYLQRNAKDMAKQ
>Mature_365_residues
SKMKKIVTALCLVGVGVGALWGSQWIMHKTSTPEFCASCHSMSYPQQEWEGSSHFANAKGVRAQCSDCHIPKEGWHYVKA
KFIALKDLWYEAQGKIENKEKYEAHRAEMAQRVWKDMKANDSETCRSCHSFDAMELSKQTKLAKQTHTEAQTNGQTCIDC
HKGIVHFLPEVHGDQNTQKSSAVQGGTLSDGSAIFATEMVKATNDKGNEVRLMPYAELMQWKVDGDQIQGTLHGWQQVGA
EAVVYQELGKRITLALMDEDARNHVQVLKIVHDAVTDSDWKEISVAVNVAKEKMTSDLTTLNQYGNQLNQTQCSGCHAAI
GADHYTANQWIGVVNSMKDRTSMKKDEVRALTIYLQRNAKDMAKQ

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorZ. Required for electron transfer to the TorZ terminal enzyme

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family

Homologues:

Organism=Escherichia coli, GI1788181, Length=348, Percent_Identity=41.6666666666667, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1787230, Length=364, Percent_Identity=37.3626373626374, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1788530, Length=168, Percent_Identity=44.6428571428571, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TORY_HAEIN (P44799)

Other databases:

- EMBL:   L42023
- PIR:   I64083
- RefSeq:   NP_438804.2
- ProteinModelPortal:   P44799
- SMR:   P44799
- GeneID:   950598
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0644
- NMPDR:   fig|71421.1.peg.614
- TIGR:   HI_0644
- HOGENOM:   HBG303867
- OMA:   WIGVVNS
- ProtClustDB:   CLSK918303
- BioCyc:   HINF71421:HI_0644-MONOMER
- GO:   GO:0006810
- InterPro:   IPR009056
- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126
- PIRSF:   PIRSF000014

Pfam domain/function: PF03264 Cytochrom_NNT; SSF46626 Cytochrome_c

EC number: NA

Molecular weight: Translated: 40943; Mature: 40812

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: BINDING 39-39 BINDING 42-42 BINDING 68-68 BINDING 71-71 BINDING 128-128 BINDING 131-131 BINDING 160-160 BINDING 163-163 BINDING 316-316 BINDING 319-319

Signals:

None

Transmembrane regions:

HASH(0xc02fcac)-;

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKMKKIVTALCLVGVGVGALWGSQWIMHKTSTPEFCASCHSMSYPQQEWEGSSHFANAK
CCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCHHHCCCCCCCCCCC
GVRAQCSDCHIPKEGWHYVKAKFIALKDLWYEAQGKIENKEKYEAHRAEMAQRVWKDMKA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
NDSETCRSCHSFDAMELSKQTKLAKQTHTEAQTNGQTCIDCHKGIVHFLPEVHGDQNTQK
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCH
SSAVQGGTLSDGSAIFATEMVKATNDKGNEVRLMPYAELMQWKVDGDQIQGTLHGWQQVG
HHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHC
AEAVVYQELGKRITLALMDEDARNHVQVLKIVHDAVTDSDWKEISVAVNVAKEKMTSDLT
HHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TLNQYGNQLNQTQCSGCHAAIGADHYTANQWIGVVNSMKDRTSMKKDEVRALTIYLQRNA
HHHHHHHHCCHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHEEEEEEEECCC
KDMAKQ
HHHHCH
>Mature Secondary Structure 
SKMKKIVTALCLVGVGVGALWGSQWIMHKTSTPEFCASCHSMSYPQQEWEGSSHFANAK
CHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCHHHCCCCCCCCCCC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HHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800