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The map label for this gene is bisC

Identifier: 16272586

GI number: 16272586

Start: 685466

End: 687943

Strand: Reverse

Name: bisC

Synonym: HI0643

Alternate gene names: 16272586

Gene position: 687943-685466 (Counterclockwise)

Preceding gene: 30995392

Following gene: 16272580

Centisome position: 37.59

GC content: 42.98

Gene sequence:

>2478_bases
ATGAAAAAGAATAACGTAAATGAACAACGTCGTGATTTTCTGAAAAAAACATCTTTAGGCGTGGCTGGTAGTGCCCTTTC
TGGTGGTATGGTGGGCGTTGTATCAAAAAGTGCGGTCGCAAAAGAAGCTGAAATGAAAACGGTAGTGACTGCCGCTCACT
GGGGATCTATTGGGGTTGTAGTACAAGATGGTAAGGTCGTGAAATCTGGTCCAGCTATTGAGCCTGCAGTGCCGAACGAA
TTGCAAACAGTTGTTGCCGATCAATTGTATAGCGAACGTCGCGTGAAATGCCCAATGGTGCGTAAAGGCTTTTTAGCTAA
TCCAGGAAAAAGCGATACTACAATGCGTGGTCGTGATGAATGGGTGCGCGTTTCTTGGGATGAAGCGTTAGATTTAGTAC
ACAATCAGCTTAAACGTGTGCGTGACGAACATGGATCAACAGGTATTTTTGCCGGTTCTTATGGTTGGTTTAGTTGTGGT
TCATTACATGCTTCTCGTACGTTATTACAGCGTTATATGAACGCTACAGGTGGTTTTGTGGGACACAAAGGGGATTACTC
TACGGGGGCTGCACAAGTAATTATGCCACATGTATTAGGCACGATTGAGGTGTACGAACAACAAACCAGCTGGGAATCCA
TATTAGAAAGTAGTGATATTATTGTGCTTTGGTCTGCAAATCCACTCACAACAATGCGTATTGCTTGGATGTCCACTGAC
CAAAAAGGGATTGAATATTTCAAGAAATTCCAAGCGAGTGGTAAACGTATTATTTGTATCGACCCACAAAAAAGCGAAAC
TTGCCAAATGTTGAATGCAGAATGGATTCCAGTGAATACAGCAACGGATGTGCCATTAATGCTTGGTATTGCACATACTT
TAGTTGAACAAGGCAAGCACGATAAAGATTTCTTGAAAAAATATACGTCAGGTTACGCTAAATTCGAAGAATATTTATTA
GGTAAAACTGATGGCCAACCAAAAACAGCGGAATGGGCAGCTAAAATTTGTGGTGTGCCAGCAGAAACCATTAAGCAACT
TGCAGCTGATTTCGCCAGTAAACGTACCATGTTAATGGGTGGCTGGGGGATGCAACGCCAACGCCATGGTGAACAAACCC
ACTGGATGTTAGTAACCCTTGCATCTATGTTAGGACAAATTGGGTTACCGGGTGGCGGCTTTGGCTTGAGTTATCATTAT
TCAAATGGTGGGGTACCAACGGCGACAGGCGGTATTATCGGCTCAATTACAGCAAGTCCATCAGGCAAAGCGGGGGCAAA
AACATGGTTGGATGATACGTCTAAATCCGCGTTCCCATTAGCGCGTATTGCTGATGTGTTACTCCATCCAGGCAAAAAGA
TTCAGTATAACGGTACTGAAATTACTTATCCTGACATCAAAGCGGTATATTGGGCAGGTGGTAACCCGTTTGTTCACCAT
CAAGATACCAATACCTTAGTGAAAGCTTTCCAGAAACCTGATGTAGTGATTGTCAATGAGGTGAACTGGACGCCAACTGC
ACGCATGGCAGATATTGTGTTACCAGCTACGACGAGTTATGAACGTAATGACTTAACCATGGCTGGCGACTACTCTATGA
TGAGTGTTTACCCGATGAAACAAGTGGTTCCACCACAATTTGAAGCAAAAAATGACTACGATATTTTCGTTGAGCTTGCT
AAACGTGCCGGTGTGGAAGAACAATACACTGAAGGTAAAACTGAAATGGAGTGGCTGGAAGAATTCTATAATGCAGCCTT
TAGTGCTGCACGTGCAAATCGTGTAGCAATGCCACGTTTTGACAAATTCTGGGCAGAAAATAAACCATTAAGTTTTGAGG
CGGGTGAAGCTGCGAAGAAATGGGTGCGTTATGGTGAATTCCGTGAAGATCCATTGCTCAATCCGCTTGGCACACCGTCA
GGTAAAATTGAAATTTTCTCTGATGTTGTTGAGAAAATGAATTATAACGATTGTAAAGGGCATCCTAGTTGGATGGAACC
TGAAGAGTTTGCGGGTAATGTGACGGAAGAATATCCGTTAGCTTTAGTGACACCACATCCTTACTATCGTTTACACAGTC
AATTGGCGCATACTTCATTACGTCAAAAATATGCGGTAAATGATCGTGAGCCAGTGATGATTCACCCTGAAGATGCGGCT
GCTCGTGGTATTAAAGACGGTGATATTGTTCGCATTCATAGCAAACGCGGTCAAGTGCTTGCAGGTGCGGCTGTAACAGA
AAATATCATCAAAGGTACTGTCGCTCTCCATGAAGGCGCATGGTATGACCCAATGTACTTAGGTGAAAGTGAAAAACCAT
TATGTAAAAATGGTTGTGCAAATGTGTTAACTCGAGATGAAGGTACATCTAAATTGGCACAAGGCAATTCACCAAATACT
TGTATCGTTCAGATTGAGAAATTTATAGGCGTAGCACCAGAAGTTACGGTATTTAAACAACCTAAACAGGTGGCGTAA

Upstream 100 bases:

>100_bases
AAAAAGATGAAGTACGTGCATTAACTATTTATCTGCAACGCAATGCCAAAGATATGGCAAAACAATAATGAATGAATTAA
CTATCTAAAACGAGGCTGAA

Downstream 100 bases:

>100_bases
AACTATTAAAAATATAACCGCACTTCAAAAAGTGCGGTTCTTCTTTTAATAATAGAACGAAGGGGCATTAACAGCACTAA
ATTCTAAACATGAGGTGTTA

Product: biotin sulfoxide reductase

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase

Number of amino acids: Translated: 825; Mature: 825

Protein sequence:

>825_residues
MKKNNVNEQRRDFLKKTSLGVAGSALSGGMVGVVSKSAVAKEAEMKTVVTAAHWGSIGVVVQDGKVVKSGPAIEPAVPNE
LQTVVADQLYSERRVKCPMVRKGFLANPGKSDTTMRGRDEWVRVSWDEALDLVHNQLKRVRDEHGSTGIFAGSYGWFSCG
SLHASRTLLQRYMNATGGFVGHKGDYSTGAAQVIMPHVLGTIEVYEQQTSWESILESSDIIVLWSANPLTTMRIAWMSTD
QKGIEYFKKFQASGKRIICIDPQKSETCQMLNAEWIPVNTATDVPLMLGIAHTLVEQGKHDKDFLKKYTSGYAKFEEYLL
GKTDGQPKTAEWAAKICGVPAETIKQLAADFASKRTMLMGGWGMQRQRHGEQTHWMLVTLASMLGQIGLPGGGFGLSYHY
SNGGVPTATGGIIGSITASPSGKAGAKTWLDDTSKSAFPLARIADVLLHPGKKIQYNGTEITYPDIKAVYWAGGNPFVHH
QDTNTLVKAFQKPDVVIVNEVNWTPTARMADIVLPATTSYERNDLTMAGDYSMMSVYPMKQVVPPQFEAKNDYDIFVELA
KRAGVEEQYTEGKTEMEWLEEFYNAAFSAARANRVAMPRFDKFWAENKPLSFEAGEAAKKWVRYGEFREDPLLNPLGTPS
GKIEIFSDVVEKMNYNDCKGHPSWMEPEEFAGNVTEEYPLALVTPHPYYRLHSQLAHTSLRQKYAVNDREPVMIHPEDAA
ARGIKDGDIVRIHSKRGQVLAGAAVTENIIKGTVALHEGAWYDPMYLGESEKPLCKNGCANVLTRDEGTSKLAQGNSPNT
CIVQIEKFIGVAPEVTVFKQPKQVA

Sequences:

>Translated_825_residues
MKKNNVNEQRRDFLKKTSLGVAGSALSGGMVGVVSKSAVAKEAEMKTVVTAAHWGSIGVVVQDGKVVKSGPAIEPAVPNE
LQTVVADQLYSERRVKCPMVRKGFLANPGKSDTTMRGRDEWVRVSWDEALDLVHNQLKRVRDEHGSTGIFAGSYGWFSCG
SLHASRTLLQRYMNATGGFVGHKGDYSTGAAQVIMPHVLGTIEVYEQQTSWESILESSDIIVLWSANPLTTMRIAWMSTD
QKGIEYFKKFQASGKRIICIDPQKSETCQMLNAEWIPVNTATDVPLMLGIAHTLVEQGKHDKDFLKKYTSGYAKFEEYLL
GKTDGQPKTAEWAAKICGVPAETIKQLAADFASKRTMLMGGWGMQRQRHGEQTHWMLVTLASMLGQIGLPGGGFGLSYHY
SNGGVPTATGGIIGSITASPSGKAGAKTWLDDTSKSAFPLARIADVLLHPGKKIQYNGTEITYPDIKAVYWAGGNPFVHH
QDTNTLVKAFQKPDVVIVNEVNWTPTARMADIVLPATTSYERNDLTMAGDYSMMSVYPMKQVVPPQFEAKNDYDIFVELA
KRAGVEEQYTEGKTEMEWLEEFYNAAFSAARANRVAMPRFDKFWAENKPLSFEAGEAAKKWVRYGEFREDPLLNPLGTPS
GKIEIFSDVVEKMNYNDCKGHPSWMEPEEFAGNVTEEYPLALVTPHPYYRLHSQLAHTSLRQKYAVNDREPVMIHPEDAA
ARGIKDGDIVRIHSKRGQVLAGAAVTENIIKGTVALHEGAWYDPMYLGESEKPLCKNGCANVLTRDEGTSKLAQGNSPNT
CIVQIEKFIGVAPEVTVFKQPKQVA
>Mature_825_residues
MKKNNVNEQRRDFLKKTSLGVAGSALSGGMVGVVSKSAVAKEAEMKTVVTAAHWGSIGVVVQDGKVVKSGPAIEPAVPNE
LQTVVADQLYSERRVKCPMVRKGFLANPGKSDTTMRGRDEWVRVSWDEALDLVHNQLKRVRDEHGSTGIFAGSYGWFSCG
SLHASRTLLQRYMNATGGFVGHKGDYSTGAAQVIMPHVLGTIEVYEQQTSWESILESSDIIVLWSANPLTTMRIAWMSTD
QKGIEYFKKFQASGKRIICIDPQKSETCQMLNAEWIPVNTATDVPLMLGIAHTLVEQGKHDKDFLKKYTSGYAKFEEYLL
GKTDGQPKTAEWAAKICGVPAETIKQLAADFASKRTMLMGGWGMQRQRHGEQTHWMLVTLASMLGQIGLPGGGFGLSYHY
SNGGVPTATGGIIGSITASPSGKAGAKTWLDDTSKSAFPLARIADVLLHPGKKIQYNGTEITYPDIKAVYWAGGNPFVHH
QDTNTLVKAFQKPDVVIVNEVNWTPTARMADIVLPATTSYERNDLTMAGDYSMMSVYPMKQVVPPQFEAKNDYDIFVELA
KRAGVEEQYTEGKTEMEWLEEFYNAAFSAARANRVAMPRFDKFWAENKPLSFEAGEAAKKWVRYGEFREDPLLNPLGTPS
GKIEIFSDVVEKMNYNDCKGHPSWMEPEEFAGNVTEEYPLALVTPHPYYRLHSQLAHTSLRQKYAVNDREPVMIHPEDAA
ARGIKDGDIVRIHSKRGQVLAGAAVTENIIKGTVALHEGAWYDPMYLGESEKPLCKNGCANVLTRDEGTSKLAQGNSPNT
CIVQIEKFIGVAPEVTVFKQPKQVA

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family

Homologues:

Organism=Escherichia coli, GI87081994, Length=818, Percent_Identity=55.2567237163814, Blast_Score=928, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=787, Percent_Identity=52.3506988564168, Blast_Score=850, Evalue=0.0,
Organism=Escherichia coli, GI1787231, Length=839, Percent_Identity=43.8617401668653, Blast_Score=681, Evalue=0.0,
Organism=Escherichia coli, GI87081797, Length=763, Percent_Identity=31.8479685452163, Blast_Score=317, Evalue=2e-87,
Organism=Escherichia coli, GI1787870, Length=857, Percent_Identity=28.9381563593932, Blast_Score=276, Evalue=3e-75,
Organism=Escherichia coli, GI171474008, Length=748, Percent_Identity=29.5454545454545, Blast_Score=260, Evalue=3e-70,
Organism=Escherichia coli, GI3868721, Length=744, Percent_Identity=23.5215053763441, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TORZ_HAEIN (P44798)

Other databases:

- EMBL:   L42023
- PIR:   H64083
- RefSeq:   NP_438803.1
- ProteinModelPortal:   P44798
- SMR:   P44798
- GeneID:   950790
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0643
- NMPDR:   fig|71421.1.peg.613
- TIGR:   HI_0643
- HOGENOM:   HBG304064
- OMA:   MIREEVM
- ProtClustDB:   CLSK892376
- BioCyc:   HINF71421:HI_0643-MONOMER
- BRENDA:   1.7.2.3
- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- Gene3D:   G3DSA:2.40.40.20
- TIGRFAMs:   TIGR00509
- TIGRFAMs:   TIGR01409

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding; SSF50692 Asp_decarb_fold

EC number: =1.7.2.3

Molecular weight: Translated: 91054; Mature: 91054

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1; PS00490 MOLYBDOPTERIN_PROK_2; PS00932 MOLYBDOPTERIN_PROK_3; PS51318 TAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNNVNEQRRDFLKKTSLGVAGSALSGGMVGVVSKSAVAKEAEMKTVVTAAHWGSIGVV
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHEEEEECCCCEEEE
VQDGKVVKSGPAIEPAVPNELQTVVADQLYSERRVKCPMVRKGFLANPGKSDTTMRGRDE
EECCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCC
WVRVSWDEALDLVHNQLKRVRDEHGSTGIFAGSYGWFSCGSLHASRTLLQRYMNATGGFV
EEEEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GHKGDYSTGAAQVIMPHVLGTIEVYEQQTSWESILESSDIIVLWSANPLTTMRIAWMSTD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCC
QKGIEYFKKFQASGKRIICIDPQKSETCQMLNAEWIPVNTATDVPLMLGIAHTLVEQGKH
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCC
DKDFLKKYTSGYAKFEEYLLGKTDGQPKTAEWAAKICGVPAETIKQLAADFASKRTMLMG
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEE
GWGMQRQRHGEQTHWMLVTLASMLGQIGLPGGGFGLSYHYSNGGVPTATGGIIGSITASP
CCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCC
SGKAGAKTWLDDTSKSAFPLARIADVLLHPGKKIQYNGTEITYPDIKAVYWAGGNPFVHH
CCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCCEEECCCCEEEEECCCCCEEEE
QDTNTLVKAFQKPDVVIVNEVNWTPTARMADIVLPATTSYERNDLTMAGDYSMMSVYPMK
CCHHHHHHHHCCCCEEEEECCCCCCCCCHHEEEECCCCCCCCCCCEEECCCCEEEECCHH
QVVPPQFEAKNDYDIFVELAKRAGVEEQYTEGKTEMEWLEEFYNAAFSAARANRVAMPRF
HCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
DKFWAENKPLSFEAGEAAKKWVRYGEFREDPLLNPLGTPSGKIEIFSDVVEKMNYNDCKG
HHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
HPSWMEPEEFAGNVTEEYPLALVTPHPYYRLHSQLAHTSLRQKYAVNDREPVMIHPEDAA
CCCCCCHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHH
ARGIKDGDIVRIHSKRGQVLAGAAVTENIIKGTVALHEGAWYDPMYLGESEKPLCKNGCA
HCCCCCCCEEEEECCCCCEEECHHHHHHHHHHEEEEECCCCCCCEECCCCCCCHHHHCHH
NVLTRDEGTSKLAQGNSPNTCIVQIEKFIGVAPEVTVFKQPKQVA
HHEECCCCCHHHHCCCCCCEEEEEEHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure
MKKNNVNEQRRDFLKKTSLGVAGSALSGGMVGVVSKSAVAKEAEMKTVVTAAHWGSIGVV
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHEEEEECCCCEEEE
VQDGKVVKSGPAIEPAVPNELQTVVADQLYSERRVKCPMVRKGFLANPGKSDTTMRGRDE
EECCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCC
WVRVSWDEALDLVHNQLKRVRDEHGSTGIFAGSYGWFSCGSLHASRTLLQRYMNATGGFV
EEEEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GHKGDYSTGAAQVIMPHVLGTIEVYEQQTSWESILESSDIIVLWSANPLTTMRIAWMSTD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCC
QKGIEYFKKFQASGKRIICIDPQKSETCQMLNAEWIPVNTATDVPLMLGIAHTLVEQGKH
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCC
DKDFLKKYTSGYAKFEEYLLGKTDGQPKTAEWAAKICGVPAETIKQLAADFASKRTMLMG
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEE
GWGMQRQRHGEQTHWMLVTLASMLGQIGLPGGGFGLSYHYSNGGVPTATGGIIGSITASP
CCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCC
SGKAGAKTWLDDTSKSAFPLARIADVLLHPGKKIQYNGTEITYPDIKAVYWAGGNPFVHH
CCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCCEEECCCCEEEEECCCCCEEEE
QDTNTLVKAFQKPDVVIVNEVNWTPTARMADIVLPATTSYERNDLTMAGDYSMMSVYPMK
CCHHHHHHHHCCCCEEEEECCCCCCCCCHHEEEECCCCCCCCCCCEEECCCCEEEECCHH
QVVPPQFEAKNDYDIFVELAKRAGVEEQYTEGKTEMEWLEEFYNAAFSAARANRVAMPRF
HCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
DKFWAENKPLSFEAGEAAKKWVRYGEFREDPLLNPLGTPSGKIEIFSDVVEKMNYNDCKG
HHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
HPSWMEPEEFAGNVTEEYPLALVTPHPYYRLHSQLAHTSLRQKYAVNDREPVMIHPEDAA
CCCCCCHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHH
ARGIKDGDIVRIHSKRGQVLAGAAVTENIIKGTVALHEGAWYDPMYLGESEKPLCKNGCA
HCCCCCCCEEEEECCCCCEEECHHHHHHHHHHEEEEECCCCCCCEECCCCCCCHHHHCHH
NVLTRDEGTSKLAQGNSPNTCIVQIEKFIGVAPEVTVFKQPKQVA
HHEECCCCCHHHHCCCCCCEEEEEEHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800