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The map label for this gene is zraR [H]

Identifier: 308535302

GI number: 308535302

Start: 2771432

End: 2772829

Strand: Reverse

Name: zraR [H]

Synonym: NA

Alternate gene names: 308535302

Gene position: 2772829-2771432 (Counterclockwise)

Preceding gene: 197118775

Following gene: 197118768

Centisome position: 60.08

GC content: 62.8

Gene sequence:

>1398_bases
GTGAGTTCGCCGACACAACAACATATGCTTTTAGTGGATGACGAGCCGGGCATTCTTACGGAGGTGTCGCTACTTCTCGC
TTCAAGCGACGTGCAGCAGGTGGCAACCCTGTCGGACAGCCGGAACGTGCTTCAGTACGTGAAGGAACACAAGGTGACTT
CGGTGATCCTGGACTGGGTGATGCCTCACGTAACCGGAGCCGAAATCCTGCACGCCCTGACCGCCGAGCACCCGGAGATT
CCGGTAATCGTCATGACCGCCATGGGGGACGTGGAGACCGCGGTTGCCTGCATGCAGCAAGGGGCGTTCGACTTCCTTAC
CAAGCCGGTCGACCCGAGCAGGCTTGTGGCAAGCGTGAAAAAGGCGCTCCAGGTAAGCGAGCTGGGCCGGCAGAACCTGA
TGCTCAAGGACTACCTGCTGGCGGATACGCTGCGAAATCCCGACGCCTTCGCCGGTATCGTCACCACCTCGAAAAAGATG
CGCGGCATCTTCCAGTACATCGAGGCGATCGCGTCCTCGCGCCTTCCGGTGCTGATCACGGGTGAGACGGGGGCGGGGAA
GGAGCTGCTGGCGCGCGCGGTGCATGAAGTCTCCGGCGTCCCCGGCCCTTTCATCTCCCTGAACGCAGCCGGGCTCGACG
ACTTCATGTTCTCGGACACCCTTTTCGGCCACAAGAAAGGGGCCTTCACCGGCGCCGACAGCAAGCGCGACGGATTGATC
GCCGCGGCAGCCGGCGGAACCCTTTTCCTTGACGAGATCGGGGACCTGAACCTCGCCTCGCAGATCAAGCTGTTGCGGCT
TTTGCAGGAGCGGGAGTACTACCGGATCGGCTCCGATCTGCTCCTGAAAAGCGACGCGCGCATCGTCGCGGCCTCCAACA
TGGACTTCACAGCGCTCAGGGCCGCAGGGAGCTTCCGCAACGACCTCTACTTCCGCCTCTGCGCCCACGAATTCCGGGTG
CCCCCCTTGAGGGAGCGTCTGGAGGATGTCGGCCCGCTGGTCGACTACTTCGCGCACAACATAGCGCTAGAGCAGGGGAA
GGCGATCCCCGCCGCTCCGCACAGCGTCATCGCGGCCCTGGCGCAGTACCGTTTCCCGGGCAACGTCCGGGAGCTCTACA
ACATGGTGCACCACGCGGTTACCTGCAACGACGGGCAACCGCTCGCGCTCTCGGACTTTCCGGGGATAGCGGCGGCGCCG
GCGCGTCCCCCCCAGAGTGTGGATGCAGCCAATCCGCTTTTTGCTTTGTTCGGGAAGTTTCCAACTGTGCTGCAGGTCGA
GGAGTATCTGATCGCCGAGGCGATGAAGCTTACCGGCGGCAACCAGACACAGGCGGCGGAACTCCTCGGACTGACGCGCC
CCACACTGAACAAGAGGTTGAAGCAGGAGCGTCAGTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: sigma-54-dependent transcriptional response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:
NA

Sequences:

>Translated_465_residues
MSSPTQQHMLLVDDEPGILTEVSLLLASSDVQQVATLSDSRNVLQYVKEHKVTSVILDWVMPHVTGAEILHALTAEHPEI
PVIVMTAMGDVETAVACMQQGAFDFLTKPVDPSRLVASVKKALQVSELGRQNLMLKDYLLADTLRNPDAFAGIVTTSKKM
RGIFQYIEAIASSRLPVLITGETGAGKELLARAVHEVSGVPGPFISLNAAGLDDFMFSDTLFGHKKGAFTGADSKRDGLI
AAAAGGTLFLDEIGDLNLASQIKLLRLLQEREYYRIGSDLLLKSDARIVAASNMDFTALRAAGSFRNDLYFRLCAHEFRV
PPLRERLEDVGPLVDYFAHNIALEQGKAIPAAPHSVIAALAQYRFPGNVRELYNMVHHAVTCNDGQPLALSDFPGIAAAP
ARPPQSVDAANPLFALFGKFPTVLQVEEYLIAEAMKLTGGNQTQAAELLGLTRPTLNKRLKQERQ
>Mature_464_residues
SSPTQQHMLLVDDEPGILTEVSLLLASSDVQQVATLSDSRNVLQYVKEHKVTSVILDWVMPHVTGAEILHALTAEHPEIP
VIVMTAMGDVETAVACMQQGAFDFLTKPVDPSRLVASVKKALQVSELGRQNLMLKDYLLADTLRNPDAFAGIVTTSKKMR
GIFQYIEAIASSRLPVLITGETGAGKELLARAVHEVSGVPGPFISLNAAGLDDFMFSDTLFGHKKGAFTGADSKRDGLIA
AAAGGTLFLDEIGDLNLASQIKLLRLLQEREYYRIGSDLLLKSDARIVAASNMDFTALRAAGSFRNDLYFRLCAHEFRVP
PLRERLEDVGPLVDYFAHNIALEQGKAIPAAPHSVIAALAQYRFPGNVRELYNMVHHAVTCNDGQPLALSDFPGIAAAPA
RPPQSVDAANPLFALFGKFPTVLQVEEYLIAEAMKLTGGNQTQAAELLGLTRPTLNKRLKQERQ

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=456, Percent_Identity=38.3771929824561, Blast_Score=277, Evalue=9e-76,
Organism=Escherichia coli, GI1788550, Length=455, Percent_Identity=36.4835164835165, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1790299, Length=470, Percent_Identity=34.468085106383, Blast_Score=245, Evalue=6e-66,
Organism=Escherichia coli, GI1788905, Length=456, Percent_Identity=34.6491228070175, Blast_Score=234, Evalue=6e-63,
Organism=Escherichia coli, GI1789087, Length=358, Percent_Identity=39.1061452513966, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87082117, Length=340, Percent_Identity=35.5882352941176, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI87082152, Length=258, Percent_Identity=43.4108527131783, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789233, Length=316, Percent_Identity=37.0253164556962, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI87081872, Length=310, Percent_Identity=37.0967741935484, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1787583, Length=246, Percent_Identity=36.5853658536585, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786524, Length=344, Percent_Identity=33.7209302325581, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1789828, Length=241, Percent_Identity=39.4190871369295, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI87081858, Length=317, Percent_Identity=28.0757097791798, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=30.8333333333333, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50521; Mature: 50390

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPTQQHMLLVDDEPGILTEVSLLLASSDVQQVATLSDSRNVLQYVKEHKVTSVILDWV
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
MPHVTGAEILHALTAEHPEIPVIVMTAMGDVETAVACMQQGAFDFLTKPVDPSRLVASVK
HHCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHH
KALQVSELGRQNLMLKDYLLADTLRNPDAFAGIVTTSKKMRGIFQYIEAIASSRLPVLIT
HHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
GETGAGKELLARAVHEVSGVPGPFISLNAAGLDDFMFSDTLFGHKKGAFTGADSKRDGLI
CCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEE
AAAAGGTLFLDEIGDLNLASQIKLLRLLQEREYYRIGSDLLLKSDARIVAASNMDFTALR
EEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEECCCCEEEECCCCHHHHH
AAGSFRNDLYFRLCAHEFRVPPLRERLEDVGPLVDYFAHNIALEQGKAIPAAPHSVIAAL
HHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AQYRFPGNVRELYNMVHHAVTCNDGQPLALSDFPGIAAAPARPPQSVDAANPLFALFGKF
HHHCCCCCHHHHHHHHHHEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
PTVLQVEEYLIAEAMKLTGGNQTQAAELLGLTRPTLNKRLKQERQ
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SSPTQQHMLLVDDEPGILTEVSLLLASSDVQQVATLSDSRNVLQYVKEHKVTSVILDWV
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
MPHVTGAEILHALTAEHPEIPVIVMTAMGDVETAVACMQQGAFDFLTKPVDPSRLVASVK
HHCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHH
KALQVSELGRQNLMLKDYLLADTLRNPDAFAGIVTTSKKMRGIFQYIEAIASSRLPVLIT
HHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
GETGAGKELLARAVHEVSGVPGPFISLNAAGLDDFMFSDTLFGHKKGAFTGADSKRDGLI
CCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEE
AAAAGGTLFLDEIGDLNLASQIKLLRLLQEREYYRIGSDLLLKSDARIVAASNMDFTALR
EEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEECCCCEEEECCCCHHHHH
AAGSFRNDLYFRLCAHEFRVPPLRERLEDVGPLVDYFAHNIALEQGKAIPAAPHSVIAAL
HHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AQYRFPGNVRELYNMVHHAVTCNDGQPLALSDFPGIAAAPARPPQSVDAANPLFALFGKF
HHHCCCCCHHHHHHHHHHEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
PTVLQVEEYLIAEAMKLTGGNQTQAAELLGLTRPTLNKRLKQERQ
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]