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The map label for this gene is fdnG-1 [H]

Identifier: 308535295

GI number: 308535295

Start: 2635756

End: 2638785

Strand: Reverse

Name: fdnG-1 [H]

Synonym: NA

Alternate gene names: 308535295

Gene position: 2638785-2635756 (Counterclockwise)

Preceding gene: 197118652

Following gene: 197118647

Centisome position: 57.18

GC content: 61.65

Gene sequence:

>3030_bases
ATGGCTGTTTCACGGAGGGAGTTTCTGCAGGGAGGGGCGCTGGCTACGGCACTGGTCCTTTCCGGCAAAAAAGCGGAAGC
GGGCGGAGCCGATGCCCCGCAGATGCGCACCAAGGGGCTGAAAAGCTCGACCACCATCTGTCCTTTCTGCGCGGTAGGTT
GTGGGCTTGTGGTGCATACCAAGAACGGCAAGATCGTCAACATCGAGGGGGACACCCAGCATCCGATCAACCAGGGTGCG
CTTTGCTCGAAAGGTAGCGCGCTGTTCCAGGTCGCCAACAACGAGCGCCGCCTGCAGAAGGTCATGTACCGTGCTCCCGG
CAGCGACAAGTTCGAAGAGAAGAGCTGGGATTGGGCGCTGGAGCGGATCAGCCAGAAGATGAAGGAGACCCGCGACAAGA
CCTTCAAGGCCAAAGAGATCAACAAGAAGGACAACAAGGAATACGTCGTGAACCGCACCGAAGGGATGGCTTTCCTGGGC
GGCGCCGGTCTCGACAACGAGGAGTGCTACCTCTGGAGCAAGTTTGCCCGCTCTATGGGGGTCGCGAACCTCGAACACCA
AGCCCGAATATGACACTCCGCTACAGTCGCCGGTCTGGCGGCTTCGTTTGGACGTGGGGCAATGACCAACCACTGGATTG
ACCTGAAGAACGCCGATGCCATCCTGGCCATCGGTTGCAACCCTGCAGAAAACCACCCGATCTCGATGAAATGGATCGAG
GCGGCTATGGATAACGGCGGCAAGCTTCTCGCCGTCGACCCGCGCTTCACCAGGACCGGCTCCAAGGCCGATCACTACGC
GCAGATCCGTCCCGGCACCGACATCGCCTTTTTGGGCGGGATGATCAACTTCGCGCTGCAGAACAACATGATCCACGAGG
AGTACGTCCGCGAGTACACCAACGCCTCCTTCATCGTAAACGAGAAGTACGACTTCAACGAGGGTATCTTCTGCGCCTTC
GACGACCAGGAGAAGACCTATGACCCGAAGGCCTGGGCCTACGCGGTCGACGGCTCCGGCAACCCCAAGCGCGACAAGTC
GCTGAAGGACCCGCGCTGCGTCTACCAGCAGCTGAAGAAGCACTACTCCCGCTACACCGTCGACATGGTCTGCTCCATCA
CCGGCACCAAGAAGGAAGACTACGTCGCCGTCGCCAAGGCATTCTGCTCCACCGGGCGCGCCGACAAGGCCGGCACCATC
CTCTACGCGATGGGTATCACACAGTCCACCCACGGCACCCAGAACGTCCGCGCGACCGCCATGCTGCAGATGCTTTTGGG
CAACATCGGCATCGCCGGCGGCGGCGTGAATGCGCTGCGCGGCGAGAGCAACGTACAGGGCTCCTCCGATTACGGCCTGC
TCTTCCACCTGCTCCCGGGCTACCTGAAGTCCCCTGAGTTCGACAACGTCGACCTGAAGGCCTACCTGGAGAAGTGGACC
CCGAAGACCAAAGACGCAAAGAGCGCCAACTGGTGGGGGAACACCCCGAAGTACACGGTGAGCCTCCTCAAAGCCTGGTA
CGGCGACAACGCCACCGCGGAGAACGGCTTCTGCTACGACTACCTCCCCAAGAGAAGCGGCAACTACTCCTTCATGAAGC
TGATGGAGAAGATGGGCAAGGGCGAACTGCAGGGCCTCGTCTGCATGGGGCAGAACCCGGCGGTAGGCGGCCCGGATTCC
CTGAAGACCCGCGAGGCGCTGGGAAAACTCGACTGGCTCGTCACCGTCGACCTCTGGGAGACCGAGACCTCCATCTTCTG
GAAGCGCCCCGGCGTGAACCCGAAGGACATCAAGACCGAGGTCTTCATGCTGCCGGCAGCCTCCTCCGTCGAGAAGGAAG
GCTCCATCTCCAACTCCGGCCGCTGGGCCCAGTGGCGCTACAAGGCTGCGGAACCGGTAGGGGATGCGAAGAGCGACCTC
TGGATCATCGATCAGTTCGCGAAGCACGTGAAGAAGGCGTACCAGAAAGGGGGAACCTTCCCCGAGCCGATCACCAAGCT
CTCCTGGAACTACGGCGAAGGCCACGAGCCTGAAGTGCACCTGGTCGCCAAGGAGATCAACGGCTACTTCACCAAGGACA
TGACCATCGTCGACAAGGACAAGACCCTCGAGTTCAAGAAGGGTGACCAGGTCCCGATGTTCAAGTACCTGCAGGACGAC
GGCTCCACCGTCTCCGGCTGCTGGATCTACTGCGGCTCCTACACGAAAGACGGCAACCAGATGGCCCGCCGCGACGCCAC
CGACCCGACCGGGCTCGGCATGTTCCCGAAGTGGTCCTGGTGCTGGCCGGTCAACCGCCGCATCATCTACAACAGGGCCT
CCGTTAACCCGGACGGCGCGCCGTTCAACCCCAAGCGCGCGGTCATCGCCTGGGACGCGCTGGAGAAGAAGTGGAAAGGC
GACGTGCCCGACGGCCCCTGGCCGCCGATGAACGACGCGAAGGAAGGGAAGTACCCCTTCATCATGGTTCCTGAAGGTCA
CGGCCGCCTCTACGCGCTAGACATGAAGGACGGTCCGTTCCCCGAGCACTACGAGCCGATCGAAAGCCCGGCCAAGAACC
TCTTGTCCAAGGTGCAGAGCAACCCGGCGGTCAAGGTCCCGGCCAACATGTCCAGCGACCTGAACAAGTACCCGTTCGTC
GGCACCACCTACAGGATGACCGAGCACTGGCAGGCAGGCGCCATGACCCGCAGCCTTCCCTGGCTGGTGGAGCTGGTCCC
GACCATGTTCGTCGAGATCTCCCAGACCCTCGCCTCCTCCAAGGGGATCAACAACGGCGACCAGGTGAAGATCACCACCG
AGCGCGGTTCCATCGAGGCGAAGGCCCTGGTCACCACCAGGCTCAAGCCCTTCAACGTGCAGGGGAAAATGGTAGAGCAG
GTGGGCCTTCCCTGGCACTTCGGTTATGCAGGTCTCGCTACCGGCGACTCGGGCAACGTCCTGACCCCGTCCGTCGGCTG
CGCCAATACGAGCATCCCCGAATTCAAGGCATTCCTCTGCAACATCGAGAAAGGGGGTAAACGCGCATGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: formate dehydrogenase major subunit

Products: NA

Alternate protein names: FDH subunit alpha; Formate dehydrogenase large subunit [H]

Number of amino acids: Translated: 1009; Mature: 1008

Protein sequence:
NA

Sequences:

>Translated_1009_residues
MAVSRREFLQGGALATALVLSGKKAEAGGADAPQMRTKGLKSSTTICPFCAVGCGLVVHTKNGKIVNIEGDTQHPINQGA
LCSKGSALFQVANNERRLQKVMYRAPGSDKFEEKSWDWALERISQKMKETRDKTFKAKEINKKDNKEYVVNRTEGMAFLG
GAGLDNEECYLWSKFARSMGVANLEHQARI*HSATVAGLAASFGRGAMTNHWIDLKNADAILAIGCNPAENHPISMKWIE
AAMDNGGKLLAVDPRFTRTGSKADHYAQIRPGTDIAFLGGMINFALQNNMIHEEYVREYTNASFIVNEKYDFNEGIFCAF
DDQEKTYDPKAWAYAVDGSGNPKRDKSLKDPRCVYQQLKKHYSRYTVDMVCSITGTKKEDYVAVAKAFCSTGRADKAGTI
LYAMGITQSTHGTQNVRATAMLQMLLGNIGIAGGGVNALRGESNVQGSSDYGLLFHLLPGYLKSPEFDNVDLKAYLEKWT
PKTKDAKSANWWGNTPKYTVSLLKAWYGDNATAENGFCYDYLPKRSGNYSFMKLMEKMGKGELQGLVCMGQNPAVGGPDS
LKTREALGKLDWLVTVDLWETETSIFWKRPGVNPKDIKTEVFMLPAASSVEKEGSISNSGRWAQWRYKAAEPVGDAKSDL
WIIDQFAKHVKKAYQKGGTFPEPITKLSWNYGEGHEPEVHLVAKEINGYFTKDMTIVDKDKTLEFKKGDQVPMFKYLQDD
GSTVSGCWIYCGSYTKDGNQMARRDATDPTGLGMFPKWSWCWPVNRRIIYNRASVNPDGAPFNPKRAVIAWDALEKKWKG
DVPDGPWPPMNDAKEGKYPFIMVPEGHGRLYALDMKDGPFPEHYEPIESPAKNLLSKVQSNPAVKVPANMSSDLNKYPFV
GTTYRMTEHWQAGAMTRSLPWLVELVPTMFVEISQTLASSKGINNGDQVKITTERGSIEAKALVTTRLKPFNVQGKMVEQ
VGLPWHFGYAGLATGDSGNVLTPSVGCANTSIPEFKAFLCNIEKGGKRA
>Mature_1008_residues
AVSRREFLQGGALATALVLSGKKAEAGGADAPQMRTKGLKSSTTICPFCAVGCGLVVHTKNGKIVNIEGDTQHPINQGAL
CSKGSALFQVANNERRLQKVMYRAPGSDKFEEKSWDWALERISQKMKETRDKTFKAKEINKKDNKEYVVNRTEGMAFLGG
AGLDNEECYLWSKFARSMGVANLEHQARI*HSATVAGLAASFGRGAMTNHWIDLKNADAILAIGCNPAENHPISMKWIEA
AMDNGGKLLAVDPRFTRTGSKADHYAQIRPGTDIAFLGGMINFALQNNMIHEEYVREYTNASFIVNEKYDFNEGIFCAFD
DQEKTYDPKAWAYAVDGSGNPKRDKSLKDPRCVYQQLKKHYSRYTVDMVCSITGTKKEDYVAVAKAFCSTGRADKAGTIL
YAMGITQSTHGTQNVRATAMLQMLLGNIGIAGGGVNALRGESNVQGSSDYGLLFHLLPGYLKSPEFDNVDLKAYLEKWTP
KTKDAKSANWWGNTPKYTVSLLKAWYGDNATAENGFCYDYLPKRSGNYSFMKLMEKMGKGELQGLVCMGQNPAVGGPDSL
KTREALGKLDWLVTVDLWETETSIFWKRPGVNPKDIKTEVFMLPAASSVEKEGSISNSGRWAQWRYKAAEPVGDAKSDLW
IIDQFAKHVKKAYQKGGTFPEPITKLSWNYGEGHEPEVHLVAKEINGYFTKDMTIVDKDKTLEFKKGDQVPMFKYLQDDG
STVSGCWIYCGSYTKDGNQMARRDATDPTGLGMFPKWSWCWPVNRRIIYNRASVNPDGAPFNPKRAVIAWDALEKKWKGD
VPDGPWPPMNDAKEGKYPFIMVPEGHGRLYALDMKDGPFPEHYEPIESPAKNLLSKVQSNPAVKVPANMSSDLNKYPFVG
TTYRMTEHWQAGAMTRSLPWLVELVPTMFVEISQTLASSKGINNGDQVKITTERGSIEAKALVTTRLKPFNVQGKMVEQV
GLPWHFGYAGLATGDSGNVLTPSVGCANTSIPEFKAFLCNIEKGGKRA

Specific function: Alpha chain of the formate dehydrogenase (FDH) catalyze the reversible two-electron oxidation of formate to carbon dioxide. FDH loses activity in the presence of air, but this activity can be restored. The alpha subunit of formate dehydrogenase forms the

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868719, Length=1035, Percent_Identity=46.6666666666667, Blast_Score=917, Evalue=0.0,
Organism=Escherichia coli, GI3868720, Length=1032, Percent_Identity=45.5426356589147, Blast_Score=881, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=618, Percent_Identity=27.5080906148867, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1788534, Length=663, Percent_Identity=24.8868778280543, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1787870, Length=454, Percent_Identity=23.1277533039648, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87081797, Length=426, Percent_Identity=24.6478873239437, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787778, Length=233, Percent_Identity=26.6094420600858, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 111624; Mature: 111493

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSRREFLQGGALATALVLSGKKAEAGGADAPQMRTKGLKSSTTICPFCAVGCGLVVHT
CCCCHHHHHCCCHHHHHHEECCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHCCCEEEEC
KNGKIVNIEGDTQHPINQGALCSKGSALFQVANNERRLQKVMYRAPGSDKFEEKSWDWAL
CCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHH
ERISQKMKETRDKTFKAKEINKKDNKEYVVNRTEGMAFLGGAGLDNEECYLWSKFARSMG
HHHHHHHHHHHHHCEEHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHCC
VANLEHQARIHSATVAGLAASFGRGAMTNHWIDLKNADAILAIGCNPAENHPISMKWIEA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCCCCCEEHHHHHH
AMDNGGKLLAVDPRFTRTGSKADHYAQIRPGTDIAFLGGMINFALQNNMIHEEYVREYTN
HHCCCCEEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCC
ASFIVNEKYDFNEGIFCAFDDQEKTYDPKAWAYAVDGSGNPKRDKSLKDPRCVYQQLKKH
CEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
YSRYTVDMVCSITGTKKEDYVAVAKAFCSTGRADKAGTILYAMGITQSTHGTQNVRATAM
HHHEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHH
LQMLLGNIGIAGGGVNALRGESNVQGSSDYGLLFHLLPGYLKSPEFDNVDLKAYLEKWTP
HHHHHHHCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCC
KTKDAKSANWWGNTPKYTVSLLKAWYGDNATAENGFCYDYLPKRSGNYSFMKLMEKMGKG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCC
ELQGLVCMGQNPAVGGPDSLKTREALGKLDWLVTVDLWETETSIFWKRPGVNPKDIKTEV
CCCEEEEECCCCCCCCCCCHHHHHHHCCEEEEEEEEEEECCCEEEEECCCCCHHHCCEEE
FMLPAASSVEKEGSISNSGRWAQWRYKAAEPVGDAKSDLWIIDQFAKHVKKAYQKGGTFP
EEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCC
EPITKLSWNYGEGHEPEVHLVAKEINGYFTKDMTIVDKDKTLEFKKGDQVPMFKYLQDDG
CCHHHEECCCCCCCCCCEEEEEEECCCEEECCCEEEECCCEEEECCCCCCCHHHHHHCCC
STVSGCWIYCGSYTKDGNQMARRDATDPTGLGMFPKWSWCWPVNRRIIYNRASVNPDGAP
CEEEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCC
FNPKRAVIAWDALEKKWKGDVPDGPWPPMNDAKEGKYPFIMVPEGHGRLYALDMKDGPFP
CCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCC
EHYEPIESPAKNLLSKVQSNPAVKVPANMSSDLNKYPFVGTTYRMTEHWQAGAMTRSLPW
CCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEHHHHHHCCHHCCCHH
LVELVPTMFVEISQTLASSKGINNGDQVKITTERGSIEAKALVTTRLKPFNVQGKMVEQV
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCHHHHHC
GLPWHFGYAGLATGDSGNVLTPSVGCANTSIPEFKAFLCNIEKGGKRA
CCCEECCCCEEEECCCCCEECCCCCCCCCCCHHHHHHHEECCCCCCCC
>Mature Secondary Structure 
AVSRREFLQGGALATALVLSGKKAEAGGADAPQMRTKGLKSSTTICPFCAVGCGLVVHT
CCCHHHHHCCCHHHHHHEECCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHCCCEEEEC
KNGKIVNIEGDTQHPINQGALCSKGSALFQVANNERRLQKVMYRAPGSDKFEEKSWDWAL
CCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHH
ERISQKMKETRDKTFKAKEINKKDNKEYVVNRTEGMAFLGGAGLDNEECYLWSKFARSMG
HHHHHHHHHHHHHCEEHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHCC
VANLEHQARIHSATVAGLAASFGRGAMTNHWIDLKNADAILAIGCNPAENHPISMKWIEA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCCCCCEEHHHHHH
AMDNGGKLLAVDPRFTRTGSKADHYAQIRPGTDIAFLGGMINFALQNNMIHEEYVREYTN
HHCCCCEEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCC
ASFIVNEKYDFNEGIFCAFDDQEKTYDPKAWAYAVDGSGNPKRDKSLKDPRCVYQQLKKH
CEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
YSRYTVDMVCSITGTKKEDYVAVAKAFCSTGRADKAGTILYAMGITQSTHGTQNVRATAM
HHHEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHH
LQMLLGNIGIAGGGVNALRGESNVQGSSDYGLLFHLLPGYLKSPEFDNVDLKAYLEKWTP
HHHHHHHCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCC
KTKDAKSANWWGNTPKYTVSLLKAWYGDNATAENGFCYDYLPKRSGNYSFMKLMEKMGKG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCC
ELQGLVCMGQNPAVGGPDSLKTREALGKLDWLVTVDLWETETSIFWKRPGVNPKDIKTEV
CCCEEEEECCCCCCCCCCCHHHHHHHCCEEEEEEEEEEECCCEEEEECCCCCHHHCCEEE
FMLPAASSVEKEGSISNSGRWAQWRYKAAEPVGDAKSDLWIIDQFAKHVKKAYQKGGTFP
EEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCC
EPITKLSWNYGEGHEPEVHLVAKEINGYFTKDMTIVDKDKTLEFKKGDQVPMFKYLQDDG
CCHHHEECCCCCCCCCCEEEEEEECCCEEECCCEEEECCCEEEECCCCCCCHHHHHHCCC
STVSGCWIYCGSYTKDGNQMARRDATDPTGLGMFPKWSWCWPVNRRIIYNRASVNPDGAP
CEEEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCC
FNPKRAVIAWDALEKKWKGDVPDGPWPPMNDAKEGKYPFIMVPEGHGRLYALDMKDGPFP
CCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCC
EHYEPIESPAKNLLSKVQSNPAVKVPANMSSDLNKYPFVGTTYRMTEHWQAGAMTRSLPW
CCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEHHHHHHCCHHCCCHH
LVELVPTMFVEISQTLASSKGINNGDQVKITTERGSIEAKALVTTRLKPFNVQGKMVEQV
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCHHHHHC
GLPWHFGYAGLATGDSGNVLTPSVGCANTSIPEFKAFLCNIEKGGKRA
CCCEECCCCEEEECCCCCEECCCCCCCCCCCHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA