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The map label for this gene is kdsB [H]

Identifier: 308535252

GI number: 308535252

Start: 1853407

End: 1854174

Strand: Direct

Name: kdsB [H]

Synonym: NA

Alternate gene names: 308535252

Gene position: 1853407-1854174 (Clockwise)

Preceding gene: 197117985

Following gene: 197117987

Centisome position: 40.16

GC content: 60.94

Gene sequence:

>768_bases
TTGAGACGCCAAATGAAAATAACCGCGGTAATACCCGCCAGGTATGCTTCTACGCGTTTTGAGGGGAAGGCCTTGGCGGA
CATCATGGGGCGCCCCATGGTGCAGCATGTTTACGAGCGCGCAGCGAAGGCGACCCTCGTGTCCGAGGTGATAGTGGCGA
CCGACGACGAGCGCATAGCCGCCGCCGTGCGCGCCTTCGGCGGCAGGGTCGAGATGACCTCGCCGACCCACGAGACCGGT
ACCGACCGCCTGGCCGAGGTGGCCGCCAGGATCGATGCGGACATCATCGTGAACGTCCAAGGGGACGAGCCGCTGATCGA
TCCCGCCATGATCGACGAGGCGATCCGGCCGCTTTTGGACGATCCGTCCATCCCGATGGCCACCTTGAAGTGCAGGATCA
AGACGCTGCACGACTTTCTTTCCCCGAACGTGGTGAAGGTCGTTTCCGACCCCACGGGGAACGTGCTCTACTTCTCGCGT
TCGCCGCTCCCCTTTTTCAGGGACAAGTGGAACGATTTGAAAGACGACGCCTTCGTCTCCGGGAAGCTTCTCTGCTACAA
GCACGTAGGTCTCTACGTCTACCGCAGGGAGTTCCTCCCCGTGTTCGCGGGATTGCAGCCGACCTACCTCGAGCTCGCCG
AGAAGCTCGAGCAGTTGCGGGTTCTGGAAAACGGCTACCGCATCAAGATCGTCGAGACCGAGTTCGAGTCCATAGGCGTA
GACACCCCGGCGGACCTGGATAAGGTGCTGGAAAGGCTGAAAGGCTAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:
NA

Sequences:

>Translated_255_residues
MRRQMKITAVIPARYASTRFEGKALADIMGRPMVQHVYERAAKATLVSEVIVATDDERIAAAVRAFGGRVEMTSPTHETG
TDRLAEVAARIDADIIVNVQGDEPLIDPAMIDEAIRPLLDDPSIPMATLKCRIKTLHDFLSPNVVKVVSDPTGNVLYFSR
SPLPFFRDKWNDLKDDAFVSGKLLCYKHVGLYVYRREFLPVFAGLQPTYLELAEKLEQLRVLENGYRIKIVETEFESIGV
DTPADLDKVLERLKG
>Mature_255_residues
MRRQMKITAVIPARYASTRFEGKALADIMGRPMVQHVYERAAKATLVSEVIVATDDERIAAAVRAFGGRVEMTSPTHETG
TDRLAEVAARIDADIIVNVQGDEPLIDPAMIDEAIRPLLDDPSIPMATLKCRIKTLHDFLSPNVVKVVSDPTGNVLYFSR
SPLPFFRDKWNDLKDDAFVSGKLLCYKHVGLYVYRREFLPVFAGLQPTYLELAEKLEQLRVLENGYRIKIVETEFESIGV
DTPADLDKVLERLKG

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=254, Percent_Identity=44.8818897637795, Blast_Score=187, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28619; Mature: 28619

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRQMKITAVIPARYASTRFEGKALADIMGRPMVQHVYERAAKATLVSEVIVATDDERIA
CCCCEEEEEEECCHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AAVRAFGGRVEMTSPTHETGTDRLAEVAARIDADIIVNVQGDEPLIDPAMIDEAIRPLLD
HHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
DPSIPMATLKCRIKTLHDFLSPNVVKVVSDPTGNVLYFSRSPLPFFRDKWNDLKDDAFVS
CCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCHHHHHCCCCCCCCCCC
GKLLCYKHVGLYVYRREFLPVFAGLQPTYLELAEKLEQLRVLENGYRIKIVETEFESIGV
CEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHCCC
DTPADLDKVLERLKG
CCCHHHHHHHHHHCC
>Mature Secondary Structure
MRRQMKITAVIPARYASTRFEGKALADIMGRPMVQHVYERAAKATLVSEVIVATDDERIA
CCCCEEEEEEECCHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AAVRAFGGRVEMTSPTHETGTDRLAEVAARIDADIIVNVQGDEPLIDPAMIDEAIRPLLD
HHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
DPSIPMATLKCRIKTLHDFLSPNVVKVVSDPTGNVLYFSRSPLPFFRDKWNDLKDDAFVS
CCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCHHHHHCCCCCCCCCCC
GKLLCYKHVGLYVYRREFLPVFAGLQPTYLELAEKLEQLRVLENGYRIKIVETEFESIGV
CEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHCCC
DTPADLDKVLERLKG
CCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA