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The map label for this gene is map [H]

Identifier: 308535202

GI number: 308535202

Start: 1108707

End: 1109453

Strand: Direct

Name: map [H]

Synonym: NA

Alternate gene names: 308535202

Gene position: 1108707-1109453 (Clockwise)

Preceding gene: 197117344

Following gene: 197117346

Centisome position: 24.02

GC content: 61.98

Gene sequence:

>747_bases
GTGATCGTACTAAAGTCCCCGGCTGAGATCGAGAAGATGGCGGCTGCCGGAAGGATCGTAGCGGAGATCCTGGCCGGGCT
CAGGGAAAAAGTGGTGCCGGGGGTTACCCTGGCACAACTTGACGCATTCGCGGAGAGGGAAACGCTGAAGAGGAAGGCGA
AGCCAGCCTTCAAGGGTTACAGCGGCTTCCCCTTTTCGCTTTGTTGCTCGGTGAACGAGCAGGTGGTTCATGGGTTTGCC
ACGCAGCGCGTCCTGGTCTCAGGCGACATCGTCAGTTTAGACTTCGGAGTCGTCTACGGCGGCTATTACGGCGATTCGGC
GATCACGGTTCCGGTGGGCGAGATATCGCAGGCCGCGGCCAAGCTGATCAAGGTCACCGAGGAGTCGCTCTACAAGGCGA
TCGAGGTCGCTGACGCCTCGCACCGCCTCTCGGACGTCTCCCACGCGGTGCAGGCCTATGTCGAGGCGCGCGGCTTTTCC
GTGGTGCGCGACTTTGTCGGGCACGGCATCGGCAAGGAACTGCACGAGGGGCCGCAGATCCCCAACTTCGGCGTTGCCGG
AAAGGGGCCCAAGCTGAAGCCGGGCATGGTGCTCGCCATCGAGCCCATGATCAACGAAAAGGGATACGACGTGCGGGTGC
TGGAGGACGGCTGGACCGCGGTCACCGCGGATGGCGGGCTCTCGGCGCACTTCGAGCACACGGTGGCAGTAACGGACAAC
GGTCCGTTGATACTTACACAAATTTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:
NA

Sequences:

>Translated_248_residues
MIVLKSPAEIEKMAAAGRIVAEILAGLREKVVPGVTLAQLDAFAERETLKRKAKPAFKGYSGFPFSLCCSVNEQVVHGFA
TQRVLVSGDIVSLDFGVVYGGYYGDSAITVPVGEISQAAAKLIKVTEESLYKAIEVADASHRLSDVSHAVQAYVEARGFS
VVRDFVGHGIGKELHEGPQIPNFGVAGKGPKLKPGMVLAIEPMINEKGYDVRVLEDGWTAVTADGGLSAHFEHTVAVTDN
GPLILTQI
>Mature_248_residues
MIVLKSPAEIEKMAAAGRIVAEILAGLREKVVPGVTLAQLDAFAERETLKRKAKPAFKGYSGFPFSLCCSVNEQVVHGFA
TQRVLVSGDIVSLDFGVVYGGYYGDSAITVPVGEISQAAAKLIKVTEESLYKAIEVADASHRLSDVSHAVQAYVEARGFS
VVRDFVGHGIGKELHEGPQIPNFGVAGKGPKLKPGMVLAIEPMINEKGYDVRVLEDGWTAVTADGGLSAHFEHTVAVTDN
GPLILTQI

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=246, Percent_Identity=40.2439024390244, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=36.5461847389558, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1786364, Length=247, Percent_Identity=42.1052631578947, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1788728, Length=210, Percent_Identity=26.6666666666667, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=240, Percent_Identity=36.6666666666667, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6323273, Length=239, Percent_Identity=40.5857740585774, Blast_Score=174, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21355531, Length=239, Percent_Identity=39.3305439330544, Blast_Score=175, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24583427, Length=244, Percent_Identity=35.655737704918, Blast_Score=172, Evalue=2e-43,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 26375; Mature: 26375

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLKSPAEIEKMAAAGRIVAEILAGLREKVVPGVTLAQLDAFAERETLKRKAKPAFKGY
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
SGFPFSLCCSVNEQVVHGFATQRVLVSGDIVSLDFGVVYGGYYGDSAITVPVGEISQAAA
CCCCCEEEECCCHHHHHHHHHCEEEEECCEEEEEECEEECCEECCCEEEEEHHHHHHHHH
KLIKVTEESLYKAIEVADASHRLSDVSHAVQAYVEARGFSVVRDFVGHGIGKELHEGPQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCCC
PNFGVAGKGPKLKPGMVLAIEPMINEKGYDVRVLEDGWTAVTADGGLSAHFEHTVAVTDN
CCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCEEEEECCCCEEEEEEEEEEECC
GPLILTQI
CCEEEEEC
>Mature Secondary Structure
MIVLKSPAEIEKMAAAGRIVAEILAGLREKVVPGVTLAQLDAFAERETLKRKAKPAFKGY
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
SGFPFSLCCSVNEQVVHGFATQRVLVSGDIVSLDFGVVYGGYYGDSAITVPVGEISQAAA
CCCCCEEEECCCHHHHHHHHHCEEEEECCEEEEEECEEECCEECCCEEEEEHHHHHHHHH
KLIKVTEESLYKAIEVADASHRLSDVSHAVQAYVEARGFSVVRDFVGHGIGKELHEGPQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCCC
PNFGVAGKGPKLKPGMVLAIEPMINEKGYDVRVLEDGWTAVTADGGLSAHFEHTVAVTDN
CCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCEEEEECCCCEEEEEEEEEEECC
GPLILTQI
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842; 7559358 [H]