Click here to switch to the map view.

The map label for this gene is trpB [H]

Identifier: 308513320

GI number: 308513320

Start: 2602792

End: 2603982

Strand: Reverse

Name: trpB [H]

Synonym: NA

Alternate gene names: 308513320

Gene position: 2603982-2602792 (Counterclockwise)

Preceding gene: 39997471

Following gene: 39997470

Centisome position: 68.27

GC content: 65.83

Gene sequence:

>1191_bases
ATGAAATTACCCGACAAACAGGGCCATTTCGGCCAGTTCGGCGGCCGCTACGTGCCGGAAACCCTCATGCCGGCCCTGTT
GGAGCTGGAGCAGGCCTACAACCACTACCGGCACGACCGCGAGTTCAAGGAGGAGTTCGACTACTACCTCCGCCAGTACG
TGGGGCGGCCCAATCCGCTCTATTTCGCCGAAAAGCTCACGCAAAAGCTCGGGGGCGCGAAGATTTACCTCAAGCGCGAG
GACCTGAACCACACCGGAGCCCACAAGGTGAACAACACCATCGGCCAGGGGCTTCTGGCCAAGCGGATGGGGAAGAAGCG
GGTCATTGCGGAGACCGGCGCGGGGCAGCACGGGGTGGCCACCGCCACCATCGCGGCCCTTTTCGGCATGGAGTGCGAAG
TCTTCATGGGAGAGGAGGATATCCGGCGCCAGGCTCTGAACGTCTTCCGGATGAAGCTCCTGGGGGCCACGGTCACGCCG
GTGACCGCCGGGACCGCCACCCTCAAGGACGCCATGAACGAGGCCCTGCGCAACTGGGTGACCTACATCCACAACACCTT
CTACGTGATCGGCACCGTGGCGGGGCCCCACCCCTATCCGGCCATGGTGCGCGACTTCCAGACGGTCATCGGCCGTGAGG
CCAAGGCCCAGCACAGGAAGATCGAGGGGCGGCTGCCGGATGTGCTGGTGGCCTGCGTCGGCGGCGGCAGCAACGCCCTG
GGGCTCTTCTACCCCTTCCTCGATGACCGGGAAGTGCGGATGGTGGGGGTGGAGGCGGCGGGCCACGGCATCGCCTCCGG
CGCCCACGCGGCGCCCCTGTGTGCCGGGAGCGTCGGGGTCCTCCACGGCAACAAGACCTATCTACTCCAGGACGAGTTCG
GCCAGATCGCCAATGCCCACTCCGTATCCGCCGGACTTGACTACCCCGGGGTCGGCCCGGAGCATGCCTGGCTCAAGGAT
GCGGGCCGGGCCGAGTACGTGTCGGTCACGGATGAGGAAGCCCTGGACGCCTTCACGCTCCTGACCCGCGAGGAGGGGAT
CATGCCGGCCCTGGAGTCGTCCCACGCCATCGCCCACGTGGTGAAGCTGGCACCGACGCTGCCGAAGGAGCAGACCATCG
TGGTCTGTCTTTCGGGCCGGGGGGACAAGGATATTCATACCGTGGCCGATGCCATGGGGGTACGTTTTTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:
NA

Sequences:

>Translated_396_residues
MKLPDKQGHFGQFGGRYVPETLMPALLELEQAYNHYRHDREFKEEFDYYLRQYVGRPNPLYFAEKLTQKLGGAKIYLKRE
DLNHTGAHKVNNTIGQGLLAKRMGKKRVIAETGAGQHGVATATIAALFGMECEVFMGEEDIRRQALNVFRMKLLGATVTP
VTAGTATLKDAMNEALRNWVTYIHNTFYVIGTVAGPHPYPAMVRDFQTVIGREAKAQHRKIEGRLPDVLVACVGGGSNAL
GLFYPFLDDREVRMVGVEAAGHGIASGAHAAPLCAGSVGVLHGNKTYLLQDEFGQIANAHSVSAGLDYPGVGPEHAWLKD
AGRAEYVSVTDEEALDAFTLLTREEGIMPALESSHAIAHVVKLAPTLPKEQTIVVCLSGRGDKDIHTVADAMGVRF
>Mature_396_residues
MKLPDKQGHFGQFGGRYVPETLMPALLELEQAYNHYRHDREFKEEFDYYLRQYVGRPNPLYFAEKLTQKLGGAKIYLKRE
DLNHTGAHKVNNTIGQGLLAKRMGKKRVIAETGAGQHGVATATIAALFGMECEVFMGEEDIRRQALNVFRMKLLGATVTP
VTAGTATLKDAMNEALRNWVTYIHNTFYVIGTVAGPHPYPAMVRDFQTVIGREAKAQHRKIEGRLPDVLVACVGGGSNAL
GLFYPFLDDREVRMVGVEAAGHGIASGAHAAPLCAGSVGVLHGNKTYLLQDEFGQIANAHSVSAGLDYPGVGPEHAWLKD
AGRAEYVSVTDEEALDAFTLLTREEGIMPALESSHAIAHVVKLAPTLPKEQTIVVCLSGRGDKDIHTVADAMGVRF

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=388, Percent_Identity=55.9278350515464, Blast_Score=447, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=57.8125, Blast_Score=458, Evalue=1e-130,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43237; Mature: 43237

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPDKQGHFGQFGGRYVPETLMPALLELEQAYNHYRHDREFKEEFDYYLRQYVGRPNPL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCH
YFAEKLTQKLGGAKIYLKREDLNHTGAHKVNNTIGQGLLAKRMGKKRVIAETGAGQHGVA
HHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
TATIAALFGMECEVFMGEEDIRRQALNVFRMKLLGATVTPVTAGTATLKDAMNEALRNWV
HHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
TYIHNTFYVIGTVAGPHPYPAMVRDFQTVIGREAKAQHRKIEGRLPDVLVACVGGGSNAL
HHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCCCCE
GLFYPFLDDREVRMVGVEAAGHGIASGAHAAPLCAGSVGVLHGNKTYLLQDEFGQIANAH
EEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCEEEEECHHHHHHHCCC
SVSAGLDYPGVGPEHAWLKDAGRAEYVSVTDEEALDAFTLLTREEGIMPALESSHAIAHV
CCCCCCCCCCCCCCCHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCHHCCHHHHHH
VKLAPTLPKEQTIVVCLSGRGDKDIHTVADAMGVRF
HHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKLPDKQGHFGQFGGRYVPETLMPALLELEQAYNHYRHDREFKEEFDYYLRQYVGRPNPL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCH
YFAEKLTQKLGGAKIYLKREDLNHTGAHKVNNTIGQGLLAKRMGKKRVIAETGAGQHGVA
HHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
TATIAALFGMECEVFMGEEDIRRQALNVFRMKLLGATVTPVTAGTATLKDAMNEALRNWV
HHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
TYIHNTFYVIGTVAGPHPYPAMVRDFQTVIGREAKAQHRKIEGRLPDVLVACVGGGSNAL
HHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCCCCE
GLFYPFLDDREVRMVGVEAAGHGIASGAHAAPLCAGSVGVLHGNKTYLLQDEFGQIANAH
EEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCEEEEECHHHHHHHCCC
SVSAGLDYPGVGPEHAWLKDAGRAEYVSVTDEEALDAFTLLTREEGIMPALESSHAIAHV
CCCCCCCCCCCCCCCHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCHHCCHHHHHH
VKLAPTLPKEQTIVVCLSGRGDKDIHTVADAMGVRF
HHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA