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The map label for this gene is lptD [H]

Identifier: 308513319

GI number: 308513319

Start: 2593636

End: 2595543

Strand: Reverse

Name: lptD [H]

Synonym: NA

Alternate gene names: 308513319

Gene position: 2595543-2593636 (Counterclockwise)

Preceding gene: 39997464

Following gene: 39997462

Centisome position: 68.05

GC content: 60.27

Gene sequence:

>1908_bases
GTGCGGATCAGGGGGAGGGGAATGACGCTCCTCTCGGACCAGGCGTTCCTGTTCGGAGACAAGGAGGAGGCTGAGGCCCG
GGGGAACGTGATCCTCATGCGCGACGGCGATACCCTGCGCGCGGACCGGATCCGGCTCAACTACCGAACCGACACCGGCG
TGGTGGAGAACGGTGCGGCCTTCATGCCCAAGGGCAACTTCCACCTGCGGGCGAAGCAAATGGAAAAGAAGGGCCCCGAC
GCGTATCGCCTGGAGCGGGGGTCCTTCACCACCTGTGACGGGGACAATCCCAGCTGGAAGTTTTCCGCTTCCGAAATCGA
CGTGAATACCGAAGGCTACGCCACCGGCAAGCACGCCCTGTTTCTCGTCAAGGATATTCCGATCCTCTACTTTCCCTACC
TCATCTATCCCGTGAAACGCGAACGGCAGTCGGGCCTGCTGACGCCCCGCACCGGCAACTCAAGCAAAAAGGGTTTCATG
CTCGATCTGGCCTACTACTGGGCCATCAGCCCCAGCCAGGACGCGACCTTCAATGTTGACATCCTGACCAAGCGCGGAAC
GGGGCTCGGCGTGGATTACCGCTACATCCGGAAGCGGGGCAGCGAGGGAAACCTGCGGGGCTTTGTCATCTACGATACCG
AGCAGCAGCGCTTCCGGGGCGATCTCTCCCAGCGGCATCAGGAGATCGTTTCGGATACGTTCAACCTGAAGTCCGACATC
AACCTGGTGGCCGACCGGAACTTCTACCGGGACTACGCCGAAGAGAGCGGGGTTTACAACCAGAGCCAGCTGGAAACCAC
CCTTTCGGCCACCAAGTATTTTGATCGCCACATCCTTTCCGGCGAGTTCCGCTACGTGCAGGACCTGCGGGAAGAGGTCC
CCGACAACCGCAAAACTCTCCAGAAGCTCCCCACCATAACCCTGACGGGCATCCGCCAGCGGCTGTGGGAAACCCCGGTC
TTCTTCTCGTTTGATTCCAATTTCATCAACTTCTATCGGAGAGAAGGGATCAAGGGGCAGCGACTCGATATCTCCCCCAT
GCTCACGGGGTACGCAAAGCCGTTCGGTCCCCTGGAGACCGCCGCCTGGGTCGGCTACCGCCAGCGTCTCTACTACGCTC
ACGGCGTTGAGAGCGGTGAAGGTATCCGCGGGTCGGGGCTTTTTTCGGCAGGAACCTCGCTTTCCTCAACGCTCTCGCGA
GTGTTCGAAACGGGCAGTGCTTCCATGCCCCGGGTTCGCCACGTGATGGTTCCCGAGGTCAGTTACAATTATGTGCAGGA
CCGGGACCAGGAATCGCTGCCGTTCTTCGATTACAACGACCGCATCGTGCATGAAAACCGGGTCGTCTACTCCCTTACCA
ATTACGTGACCGGCCGATTCAACCGGGGCGACGGGCCGCCCGAGTACCGGGACCTCCTCTATCTCCGCATCGCCCAGGGC
TATGAGTTCAGCGGTACCCGCCGCGATCTCCTCACCCTGGTGGATGAGAAGCGGCACTTCACCGACGTGCAGGTGGAGGC
CACGGTGCACCCTCACCGGCTGGTGTCGTTATCCACTGACGTTCGCTATAATCCCTACCGCACGATCCTTTCCACGGTGG
CTGTGTCGGCCGACGCCCGCGATGAAAAGGGCAATACGGCCTCCATTCTGTATCGCCACGCCCGGGACGAGGTGGAATAT
CTGGAGGCGAGGACCTCGCTGGCCCTTTTCGCACCGGTGTTCGTTAATTACGCCAACCGCTACTCCTTTGATCGCAAGGG
GACCCTCGAGTCCTTCTATTCGCTGGAGTACCGGCACCAGTGCTGGAGCGTGAGCTTTTCCTACCGCGACCGGCCCGATA
CCAACGAATTCTTTGTTACCTTTGCCCTGGCCGGTATCGGTTCAGTGGGCAAGATACGGGCATTCTAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:
NA

Sequences:

>Translated_635_residues
MRIRGRGMTLLSDQAFLFGDKEEAEARGNVILMRDGDTLRADRIRLNYRTDTGVVENGAAFMPKGNFHLRAKQMEKKGPD
AYRLERGSFTTCDGDNPSWKFSASEIDVNTEGYATGKHALFLVKDIPILYFPYLIYPVKRERQSGLLTPRTGNSSKKGFM
LDLAYYWAISPSQDATFNVDILTKRGTGLGVDYRYIRKRGSEGNLRGFVIYDTEQQRFRGDLSQRHQEIVSDTFNLKSDI
NLVADRNFYRDYAEESGVYNQSQLETTLSATKYFDRHILSGEFRYVQDLREEVPDNRKTLQKLPTITLTGIRQRLWETPV
FFSFDSNFINFYRREGIKGQRLDISPMLTGYAKPFGPLETAAWVGYRQRLYYAHGVESGEGIRGSGLFSAGTSLSSTLSR
VFETGSASMPRVRHVMVPEVSYNYVQDRDQESLPFFDYNDRIVHENRVVYSLTNYVTGRFNRGDGPPEYRDLLYLRIAQG
YEFSGTRRDLLTLVDEKRHFTDVQVEATVHPHRLVSLSTDVRYNPYRTILSTVAVSADARDEKGNTASILYRHARDEVEY
LEARTSLALFAPVFVNYANRYSFDRKGTLESFYSLEYRHQCWSVSFSYRDRPDTNEFFVTFALAGIGSVGKIRAF
>Mature_635_residues
MRIRGRGMTLLSDQAFLFGDKEEAEARGNVILMRDGDTLRADRIRLNYRTDTGVVENGAAFMPKGNFHLRAKQMEKKGPD
AYRLERGSFTTCDGDNPSWKFSASEIDVNTEGYATGKHALFLVKDIPILYFPYLIYPVKRERQSGLLTPRTGNSSKKGFM
LDLAYYWAISPSQDATFNVDILTKRGTGLGVDYRYIRKRGSEGNLRGFVIYDTEQQRFRGDLSQRHQEIVSDTFNLKSDI
NLVADRNFYRDYAEESGVYNQSQLETTLSATKYFDRHILSGEFRYVQDLREEVPDNRKTLQKLPTITLTGIRQRLWETPV
FFSFDSNFINFYRREGIKGQRLDISPMLTGYAKPFGPLETAAWVGYRQRLYYAHGVESGEGIRGSGLFSAGTSLSSTLSR
VFETGSASMPRVRHVMVPEVSYNYVQDRDQESLPFFDYNDRIVHENRVVYSLTNYVTGRFNRGDGPPEYRDLLYLRIAQG
YEFSGTRRDLLTLVDEKRHFTDVQVEATVHPHRLVSLSTDVRYNPYRTILSTVAVSADARDEKGNTASILYRHARDEVEY
LEARTSLALFAPVFVNYANRYSFDRKGTLESFYSLEYRHQCWSVSFSYRDRPDTNEFFVTFALAGIGSVGKIRAF

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

Organism=Escherichia coli, GI1786239, Length=284, Percent_Identity=25, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543 [H]

Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 73005; Mature: 73005

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRGRGMTLLSDQAFLFGDKEEAEARGNVILMRDGDTLRADRIRLNYRTDTGVVENGAA
CEECCCCCEEEECCEEEECCHHHHHCCCCEEEEECCCCEEEEEEEEEEECCCCEEECCCE
FMPKGNFHLRAKQMEKKGPDAYRLERGSFTTCDGDNPSWKFSASEIDVNTEGYATGKHAL
ECCCCCEEEEHHHHHHCCCCCEEEECCCEEECCCCCCCEEEECCEEEECCCCCCCCCEEE
FLVKDIPILYFPYLIYPVKRERQSGLLTPRTGNSSKKGFMLDLAYYWAISPSQDATFNVD
EEEECCCHHHHHHHHEEECHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEE
ILTKRGTGLGVDYRYIRKRGSEGNLRGFVIYDTEQQRFRGDLSQRHQEIVSDTFNLKSDI
EEEECCCCCCCCHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC
NLVADRNFYRDYAEESGVYNQSQLETTLSATKYFDRHILSGEFRYVQDLREEVPDNRKTL
EEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
QKLPTITLTGIRQRLWETPVFFSFDSNFINFYRREGIKGQRLDISPMLTGYAKPFGPLET
HHCCCEEEHHHHHHHHCCCEEEEECCHHHHHHHHCCCCCCEEECCHHHHCCCCCCCCHHH
AAWVGYRQRLYYAHGVESGEGIRGSGLFSAGTSLSSTLSRVFETGSASMPRVRHVMVPEV
HHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCC
SYNYVQDRDQESLPFFDYNDRIVHENRVVYSLTNYVTGRFNRGDGPPEYRDLLYLRIAQG
CCCHHCCCCCCCCCEECCCCCEEECCEEEEEEEHHHEECCCCCCCCHHHHHEEEEEEECC
YEFSGTRRDLLTLVDEKRHFTDVQVEATVHPHRLVSLSTDVRYNPYRTILSTVAVSADAR
CCCCCCHHHHHHHHHCCCCCEEEEEEEEECCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
DEKGNTASILYRHARDEVEYLEARTSLALFAPVFVNYANRYSFDRKGTLESFYSLEYRHQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
CWSVSFSYRDRPDTNEFFVTFALAGIGSVGKIRAF
EEEEEEECCCCCCCCCEEEEEEECCCCCCCCEECC
>Mature Secondary Structure
MRIRGRGMTLLSDQAFLFGDKEEAEARGNVILMRDGDTLRADRIRLNYRTDTGVVENGAA
CEECCCCCEEEECCEEEECCHHHHHCCCCEEEEECCCCEEEEEEEEEEECCCCEEECCCE
FMPKGNFHLRAKQMEKKGPDAYRLERGSFTTCDGDNPSWKFSASEIDVNTEGYATGKHAL
ECCCCCEEEEHHHHHHCCCCCEEEECCCEEECCCCCCCEEEECCEEEECCCCCCCCCEEE
FLVKDIPILYFPYLIYPVKRERQSGLLTPRTGNSSKKGFMLDLAYYWAISPSQDATFNVD
EEEECCCHHHHHHHHEEECHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEE
ILTKRGTGLGVDYRYIRKRGSEGNLRGFVIYDTEQQRFRGDLSQRHQEIVSDTFNLKSDI
EEEECCCCCCCCHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC
NLVADRNFYRDYAEESGVYNQSQLETTLSATKYFDRHILSGEFRYVQDLREEVPDNRKTL
EEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
QKLPTITLTGIRQRLWETPVFFSFDSNFINFYRREGIKGQRLDISPMLTGYAKPFGPLET
HHCCCEEEHHHHHHHHCCCEEEEECCHHHHHHHHCCCCCCEEECCHHHHCCCCCCCCHHH
AAWVGYRQRLYYAHGVESGEGIRGSGLFSAGTSLSSTLSRVFETGSASMPRVRHVMVPEV
HHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCC
SYNYVQDRDQESLPFFDYNDRIVHENRVVYSLTNYVTGRFNRGDGPPEYRDLLYLRIAQG
CCCHHCCCCCCCCCEECCCCCEEECCEEEEEEEHHHEECCCCCCCCHHHHHEEEEEEECC
YEFSGTRRDLLTLVDEKRHFTDVQVEATVHPHRLVSLSTDVRYNPYRTILSTVAVSADAR
CCCCCCHHHHHHHHHCCCCCEEEEEEEEECCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
DEKGNTASILYRHARDEVEYLEARTSLALFAPVFVNYANRYSFDRKGTLESFYSLEYRHQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
CWSVSFSYRDRPDTNEFFVTFALAGIGSVGKIRAF
EEEEEEECCCCCCCCCEEEEEEECCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA