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The map label for this gene is trxB [H]

Identifier: 304570587

GI number: 304570587

Start: 2109783

End: 2110706

Strand: Reverse

Name: trxB [H]

Synonym: NA

Alternate gene names: 304570587

Gene position: 2110706-2109783 (Counterclockwise)

Preceding gene: 78357110

Following gene: 78357108

Centisome position: 56.58

GC content: 53.35

Gene sequence:

>924_bases
ATGAAGCTCTACGATTCCATTGTTATCGGAGGGGGGCCGGCAGGCATGACGGCCGCCCTTTATCTTCTTCGTTCCGGTGT
TTCCGTTGCATGGTGCGAAAAGCTGTCACCCGGCGGTCAGATGCTGATGACGGAAGAAATCGAGAATTACCCGGGATTTC
CCAAAGGATTGAAAGGGTACGAGCTGGTGGATTTGTTTGCCGCTCACCTCGATGGCTGGTCATTTGATAAATATACTGAC
GAAGTGGCCGAAATTATTCCCGGAAACGGCGTGCACAGGGTGCGTGTGGGCGATGAGTGGGTTGAAGGAAAGACCCTCAT
TATCTGCTCCGGTGCCCGTTACAAGCGTCTGGGGCTGCCTAACGAAGAAAGGTTGACCGGTAAGGGGATTTCATACTGCG
CGCTGTGTGACGGCAACTTTTTCCGCGGTCAGGAAGTCGGCGTCGTCGGCGGAGGGAACTCCGCGCTCGAAGAGTCGCTG
TATCTTTCTAAGCTTGTGAAAAAGCTGCACCTGATCCACCGTCGCGATGATTTCCGCGCTATGAAATGCTATCAGGACAA
GGTGTGCATCAAGCCTGATATCGAGGTTGTGCGCAGCACCGTAGTAACTGAGATTCACGGTGAAAATGCTCTCGAAGGCG
TTACCTTGCGCAACCTGAAGACCGGTGAAGAGTATTTTCTTAAACTTGATGGGCTGTTTGTGTTTATCGGCTTTGAGCCT
GTTACCGGATTTTTCCCGGACCAGCTCGGCGTTGATGCGCAGGGGTTCATCATTACGGACGTGGAAATGGCGACGAATGT
TCCCGGTATTTTTGCCGCGGGCGATGTGCGTTCCAAGCTGTGCCGTCAGGTGACTACCGCCGTTGGCGACGGTGCCACAG
CAGCCAATTCTGCTTTCCTTTATCTGGAACAGCTTGATGCGTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: thioredoxin reductase (NADPH)

Products: NA

Alternate protein names: TRXR; General stress protein 35; GSP35 [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:
NA

Sequences:

>Translated_307_residues
MKLYDSIVIGGGPAGMTAALYLLRSGVSVAWCEKLSPGGQMLMTEEIENYPGFPKGLKGYELVDLFAAHLDGWSFDKYTD
EVAEIIPGNGVHRVRVGDEWVEGKTLIICSGARYKRLGLPNEERLTGKGISYCALCDGNFFRGQEVGVVGGGNSALEESL
YLSKLVKKLHLIHRRDDFRAMKCYQDKVCIKPDIEVVRSTVVTEIHGENALEGVTLRNLKTGEEYFLKLDGLFVFIGFEP
VTGFFPDQLGVDAQGFIITDVEMATNVPGIFAAGDVRSKLCRQVTTAVGDGATAANSAFLYLEQLDA
>Mature_307_residues
MKLYDSIVIGGGPAGMTAALYLLRSGVSVAWCEKLSPGGQMLMTEEIENYPGFPKGLKGYELVDLFAAHLDGWSFDKYTD
EVAEIIPGNGVHRVRVGDEWVEGKTLIICSGARYKRLGLPNEERLTGKGISYCALCDGNFFRGQEVGVVGGGNSALEESL
YLSKLVKKLHLIHRRDDFRAMKCYQDKVCIKPDIEVVRSTVVTEIHGENALEGVTLRNLKTGEEYFLKLDGLFVFIGFEP
VTGFFPDQLGVDAQGFIITDVEMATNVPGIFAAGDVRSKLCRQVTTAVGDGATAANSAFLYLEQLDA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=309, Percent_Identity=37.5404530744337, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI87081763, Length=306, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6320560, Length=312, Percent_Identity=36.8589743589744, Blast_Score=182, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6321898, Length=315, Percent_Identity=35.5555555555556, Blast_Score=177, Evalue=2e-45,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33508; Mature: 33508

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYDSIVIGGGPAGMTAALYLLRSGVSVAWCEKLSPGGQMLMTEEIENYPGFPKGLKGY
CCCCCEEEECCCCHHHHHHHHHHHCCCCEEEHHHCCCCCCEEEHHHHHCCCCCCCCCCCH
ELVDLFAAHLDGWSFDKYTDEVAEIIPGNGVHRVRVGDEWVEGKTLIICSGARYKRLGLP
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCEEECCCC
NEERLTGKGISYCALCDGNFFRGQEVGVVGGGNSALEESLYLSKLVKKLHLIHRRDDFRA
CCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
MKCYQDKVCIKPDIEVVRSTVVTEIHGENALEGVTLRNLKTGEEYFLKLDGLFVFIGFEP
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHEEEECCEEEEEEEEC
VTGFFPDQLGVDAQGFIITDVEMATNVPGIFAAGDVRSKLCRQVTTAVGDGATAANSAFL
CCCCCCHHHCCCCCCEEEEEHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCEEE
YLEQLDA
EEEECCC
>Mature Secondary Structure
MKLYDSIVIGGGPAGMTAALYLLRSGVSVAWCEKLSPGGQMLMTEEIENYPGFPKGLKGY
CCCCCEEEECCCCHHHHHHHHHHHCCCCEEEHHHCCCCCCEEEHHHHHCCCCCCCCCCCH
ELVDLFAAHLDGWSFDKYTDEVAEIIPGNGVHRVRVGDEWVEGKTLIICSGARYKRLGLP
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCEEECCCC
NEERLTGKGISYCALCDGNFFRGQEVGVVGGGNSALEESLYLSKLVKKLHLIHRRDDFRA
CCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
MKCYQDKVCIKPDIEVVRSTVVTEIHGENALEGVTLRNLKTGEEYFLKLDGLFVFIGFEP
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHEEEECCEEEEEEEEC
VTGFFPDQLGVDAQGFIITDVEMATNVPGIFAAGDVRSKLCRQVTTAVGDGATAANSAFL
CCCCCCHHHCCCCCCEEEEEHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCEEE
YLEQLDA
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]