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The map label for this gene is thyX [H]

Identifier: 30263688

GI number: 30263688

Start: 3495997

End: 3496755

Strand: Reverse

Name: thyX [H]

Synonym: BA_3813

Alternate gene names: 30263688

Gene position: 3496755-3495997 (Counterclockwise)

Preceding gene: 30263689

Following gene: 30263686

Centisome position: 66.89

GC content: 40.97

Gene sequence:

>759_bases
ATGGATGTAAAGCTACTAGCACATACGCAATTATCTGAGGAATTTGTTAATTATTTATCTGTTGTATTTGGTATTGGAGA
TGAAGGCTTTGACCCTACCCATGGGCAAGTAGTAGCTTTATCGGCAATCCGTACGTGTTACTCGCCAAATAAGCCTAGTA
GGATTGTGTCTTTAGAGGGAGAGAAGTACTTCAAGGGCAAAGCAACTGATGGAAAGGGTGGAAAAGAAGTAGATCGACTT
ATTAGACATATTGTAGGTTCGGGGCATGCCTCAACTCTGGAGCATCTAACATATACCTTTGCAGTAGAAGGAGTTAGCAG
AGCATTACTCGCTCAGTTAACACGTCACCGTGTAGGATTCAGTTACTCAGTCCAATCCCAAAGATATGTACGCATGGGAA
GTAATGATAAGATAGGCGGTTTTGATTATGTAGTGCCTGAAACAGTTAAGGCTAAAGGAGAACAAGTAGTTAATGCTTAC
AACGAAATGATGTACAAACTCCAAAGTGGTTATGATCTACTTAGAACATTAGGAATTCCTGCTGAGGATGCTCGTAGCGT
ACTTCCAAACGCAGCCGCAACTAACCTAGTCTTAACAGTCAATTTACGTGGGCTTTTAGATTTCTATAATAAGCGTCGAA
AAGGGAAAGGTGCTCAAGCTGAAATTGCGGAGTTGGCAGAGCAATTAAGGCAAGAAGTTGTAAAAGTTGAAAAGTGGGTA
GACGAGTTTTTTTGGAAGTGGAAAGTAACAGAAGTCTAG

Upstream 100 bases:

>100_bases
ATTCAAGTGACGAGCTTAATTTATAAGAAAGGACTAATTACAGTATATAAAAACTTGTCTAACAAGGTTACAAATTCATT
AAGAAATGGAGAATTTAAAT

Downstream 100 bases:

>100_bases
AAAGATTACAAATAAAAGAGCAGCTAGCAAAAGCTAACTGCTCATCTCCAGGGGAATTGGAGACTGCTGTATCTATAGTA
TTGACGGAATATTGAGTTTT

Product: prophage LambdaBa01, thymidylate synthase-complementing protein

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MDVKLLAHTQLSEEFVNYLSVVFGIGDEGFDPTHGQVVALSAIRTCYSPNKPSRIVSLEGEKYFKGKATDGKGGKEVDRL
IRHIVGSGHASTLEHLTYTFAVEGVSRALLAQLTRHRVGFSYSVQSQRYVRMGSNDKIGGFDYVVPETVKAKGEQVVNAY
NEMMYKLQSGYDLLRTLGIPAEDARSVLPNAAATNLVLTVNLRGLLDFYNKRRKGKGAQAEIAELAEQLRQEVVKVEKWV
DEFFWKWKVTEV

Sequences:

>Translated_252_residues
MDVKLLAHTQLSEEFVNYLSVVFGIGDEGFDPTHGQVVALSAIRTCYSPNKPSRIVSLEGEKYFKGKATDGKGGKEVDRL
IRHIVGSGHASTLEHLTYTFAVEGVSRALLAQLTRHRVGFSYSVQSQRYVRMGSNDKIGGFDYVVPETVKAKGEQVVNAY
NEMMYKLQSGYDLLRTLGIPAEDARSVLPNAAATNLVLTVNLRGLLDFYNKRRKGKGAQAEIAELAEQLRQEVVKVEKWV
DEFFWKWKVTEV
>Mature_252_residues
MDVKLLAHTQLSEEFVNYLSVVFGIGDEGFDPTHGQVVALSAIRTCYSPNKPSRIVSLEGEKYFKGKATDGKGGKEVDRL
IRHIVGSGHASTLEHLTYTFAVEGVSRALLAQLTRHRVGFSYSVQSQRYVRMGSNDKIGGFDYVVPETVKAKGEQVVNAY
NEMMYKLQSGYDLLRTLGIPAEDARSVLPNAAATNLVLTVNLRGLLDFYNKRRKGKGAQAEIAELAEQLRQEVVKVEKWV
DEFFWKWKVTEV

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 28177; Mature: 28177

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVKLLAHTQLSEEFVNYLSVVFGIGDEGFDPTHGQVVALSAIRTCYSPNKPSRIVSLEG
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCCCCCEEEEECC
EKYFKGKATDGKGGKEVDRLIRHIVGSGHASTLEHLTYTFAVEGVSRALLAQLTRHRVGF
CEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SYSVQSQRYVRMGSNDKIGGFDYVVPETVKAKGEQVVNAYNEMMYKLQSGYDLLRTLGIP
EEECCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AEDARSVLPNAAATNLVLTVNLRGLLDFYNKRRKGKGAQAEIAELAEQLRQEVVKVEKWV
HHHHHHHCCCCHHCCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
DEFFWKWKVTEV
HHHHHHEEECCC
>Mature Secondary Structure
MDVKLLAHTQLSEEFVNYLSVVFGIGDEGFDPTHGQVVALSAIRTCYSPNKPSRIVSLEG
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCCCCCEEEEECC
EKYFKGKATDGKGGKEVDRLIRHIVGSGHASTLEHLTYTFAVEGVSRALLAQLTRHRVGF
CEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SYSVQSQRYVRMGSNDKIGGFDYVVPETVKAKGEQVVNAYNEMMYKLQSGYDLLRTLGIP
EEECCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AEDARSVLPNAAATNLVLTVNLRGLLDFYNKRRKGKGAQAEIAELAEQLRQEVVKVEKWV
HHHHHHHCCCCHHCCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
DEFFWKWKVTEV
HHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]