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The map label for this gene is fhuG [H]

Identifier: 30263433

GI number: 30263433

Start: 3240381

End: 3241397

Strand: Reverse

Name: fhuG [H]

Synonym: BA_3533

Alternate gene names: 30263433

Gene position: 3241397-3240381 (Counterclockwise)

Preceding gene: 30263434

Following gene: 30263432

Centisome position: 62.01

GC content: 38.15

Gene sequence:

>1017_bases
GTGAAGAAGATTTTAAACACAGATAAGAAGAGAGCTATTACTGTAACTACAATATTTGGTTGTATTGGTATCGCTGTCAT
TTTAATTAGTTTAAATACAGGAACATTGAGTATAGCGCCACTTAAAGTAATTCAAACACTTTTTGGTTATGGTGATTTTG
AGAGCGCAACCGTGCTATATGATTATCGTATGCCAAGAATTATAATCACCATGTTAGCTGGCATTGGCCTTGGGATTTCC
GGTGCGATTTTGCAAGGATTATCACGTAATGCACTTGCAGACCCTGGTATTTTAGGATTACATTCCGGTGCGTCTTTCGG
TCTTATCGTATTTGTTACTTTCTTTCATTCTATTAATGAGAATGCATCCATTTTAATACCGTTATTTACATTTGGCGGAG
GAGTATTAGCTGCATTTCTTATTATTTTACTTGCGAGTGATCGGTCAAAAGGTTTACTTCCCATTAGACTTATTCTCGTT
GGTATTGCAGTTTCAGCTGGCTTTAGTGCAATTTCATTATTTTTCTCTCTCAAGTTAAATGATGAGACGTATACATTCGC
TTCTAGATGGCTAGTTGGTAACGTGTGGGGAAGGGACTGGATTCATGTCCTTGCATTATTACCTTGGATTTTCATACTAA
CCCCTTATGCATGGCTAAAATCTAAAACGTTAAATGCCTTGTCACTAGGTGATAGTGTAGCAGCAGGACTAGGTGTTTCT
GTTCAAAAAGAACGGTTACTACTTTTAGCTACAGCGGTTGGATTATCTTGCGGGAGTGTAGCGATGGCAGGAGGGATTGG
TTTTATCGGTTTAGTTGCTCCGCATATCGCAAGGAAGTTAGTAGGTACTACATATCAACACTTCCTTCCTTTAGCTGGCA
TTATCGGAATGATTATTTTAGTGCTAGCAGATACGATAGGTCGTTCTATATTTGAGCCAAACTCTATTCCAGCTGGTGTA
GTAGTGGCAGCTTTAGGAGCACCGTATTTTCTTTATTTACTTACAAAAACAAAATAA

Upstream 100 bases:

>100_bases
AGTAAACCCTCCTAAAGAACTTGCGATAGGGATTATGGTAGCTCTCATTGGAGTTCCGTTTTTCCTATATATAGCACGTA
AAGTTGGGAGGGAACTATAA

Downstream 100 bases:

>100_bases
ATACTTCAAAGAGGAGAACATATGAAAAAGAAACTTACTATTTTATTTAGCATCGTGTGTATTTTAGTATTAGCAGCATG
TGGTCAAACGAAAGCTAATA

Product: iron compound ABC transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKKILNTDKKRAITVTTIFGCIGIAVILISLNTGTLSIAPLKVIQTLFGYGDFESATVLYDYRMPRIIITMLAGIGLGIS
GAILQGLSRNALADPGILGLHSGASFGLIVFVTFFHSINENASILIPLFTFGGGVLAAFLIILLASDRSKGLLPIRLILV
GIAVSAGFSAISLFFSLKLNDETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNALSLGDSVAAGLGVS
VQKERLLLLATAVGLSCGSVAMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIILVLADTIGRSIFEPNSIPAGV
VVAALGAPYFLYLLTKTK

Sequences:

>Translated_338_residues
MKKILNTDKKRAITVTTIFGCIGIAVILISLNTGTLSIAPLKVIQTLFGYGDFESATVLYDYRMPRIIITMLAGIGLGIS
GAILQGLSRNALADPGILGLHSGASFGLIVFVTFFHSINENASILIPLFTFGGGVLAAFLIILLASDRSKGLLPIRLILV
GIAVSAGFSAISLFFSLKLNDETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNALSLGDSVAAGLGVS
VQKERLLLLATAVGLSCGSVAMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIILVLADTIGRSIFEPNSIPAGV
VVAALGAPYFLYLLTKTK
>Mature_338_residues
MKKILNTDKKRAITVTTIFGCIGIAVILISLNTGTLSIAPLKVIQTLFGYGDFESATVLYDYRMPRIIITMLAGIGLGIS
GAILQGLSRNALADPGILGLHSGASFGLIVFVTFFHSINENASILIPLFTFGGGVLAAFLIILLASDRSKGLLPIRLILV
GIAVSAGFSAISLFFSLKLNDETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNALSLGDSVAAGLGVS
VQKERLLLLATAVGLSCGSVAMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIILVLADTIGRSIFEPNSIPAGV
VVAALGAPYFLYLLTKTK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=311, Percent_Identity=34.0836012861736, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1786804, Length=308, Percent_Identity=35.0649350649351, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786805, Length=312, Percent_Identity=35.2564102564103, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786347, Length=288, Percent_Identity=31.5972222222222, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1788004, Length=290, Percent_Identity=36.551724137931, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790741, Length=300, Percent_Identity=32, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35801; Mature: 35801

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILNTDKKRAITVTTIFGCIGIAVILISLNTGTLSIAPLKVIQTLFGYGDFESATVLY
CCCCCCCCCCCEEEHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHCCCCCCCEEEEE
DYRMPRIIITMLAGIGLGISGAILQGLSRNALADPGILGLHSGASFGLIVFVTFFHSINE
ECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCC
NASILIPLFTFGGGVLAAFLIILLASDRSKGLLPIRLILVGIAVSAGFSAISLFFSLKLN
CCEEEEEHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEEEEEC
DETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNALSLGDSVAAGLGVS
CCHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCHHHHCCCCC
VQKERLLLLATAVGLSCGSVAMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIIL
CCHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLADTIGRSIFEPNSIPAGVVVAALGAPYFLYLLTKTK
HHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCC
>Mature Secondary Structure
MKKILNTDKKRAITVTTIFGCIGIAVILISLNTGTLSIAPLKVIQTLFGYGDFESATVLY
CCCCCCCCCCCEEEHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHCCCCCCCEEEEE
DYRMPRIIITMLAGIGLGISGAILQGLSRNALADPGILGLHSGASFGLIVFVTFFHSINE
ECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCC
NASILIPLFTFGGGVLAAFLIILLASDRSKGLLPIRLILVGIAVSAGFSAISLFFSLKLN
CCEEEEEHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEEEEEC
DETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNALSLGDSVAAGLGVS
CCHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCHHHHCCCCC
VQKERLLLLATAVGLSCGSVAMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIIL
CCHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLADTIGRSIFEPNSIPAGVVVAALGAPYFLYLLTKTK
HHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]