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The map label for this gene is ydhC [C]

Identifier: 30263419

GI number: 30263419

Start: 3229513

End: 3230712

Strand: Reverse

Name: ydhC [C]

Synonym: BA_3518

Alternate gene names: 30263419

Gene position: 3230712-3229513 (Counterclockwise)

Preceding gene: 30263421

Following gene: 30263418

Centisome position: 61.8

GC content: 34.17

Gene sequence:

>1200_bases
ATGAAAAAAGTCTCAGTACCATCACTTTTATTAATGATTATTCTTGTCGCATTTCCGCAAATTAGTGAAACGATTTATAC
ACCGTCTTTACCAGACATTTCAAAGGCGCTGCACGTAAGTAATAATGAGGTACAGTTAACACTTAGTGTGTATTTTGCTG
GATTTGCTTTAGGTGTATTTTTTATTGGATGGCTATCGGATATAATTGGCCGTCGTCCGGCAATGTTATTTGGAATTGTT
GTATATGGCATTGGGAGTTTCTTATGCTTTATTGCAAATTCCATTGAAGTTTTATTAGTAAGTCGTTTTATTCAAGCATT
TGGAGCAAGTGCAGGATCAGTTGTGACGCAAACGATTCTTCGTGAAAGTGTAGAAGGGCATAAGAGGCATGTTATGTTTG
CTCAAATCTCGGCAGTCATTGCTTTTACACCAGCGATAGGGCCATTAATTGGTGGATTTCTTGATCAAATGTTTGGATTT
AAAATAGTATTTTTAAGTTTAGTAGTTATGAGTGTCGGAATTTTTCTGTATACGTTTGTTTCTCTTCCAGAAACAAAAAC
GAGCTCAGTAACAAATAAAATAAATGTTTTTTCAGTATTGAAAAGATTAATTACAAATCCGAAAGTAGTAACATATGGGC
TATTAATTGGAGGTGCAAATGGTGTTTTATTTAGCTATTATGCAGAAGCACCGTTTATCTTTATTGAATACTTTCGATTA
TCGCCTAGTATGTATGGATTTTTAGGAATTGTTGTTGCTTCTGCTTCTATTATTGGAGCGAAAGTTTCAAAACGATTGCT
TGCAACTTATAAACCAGAGAAAATTATATATATCGGTTGTCTTGTAATGGTAGTTGGAGCAGTCGCTTTATCTCTTATTA
CTTCAGTTGGATCAAATCCAAACATAATATATATGGTCGGATTTTTAGTAGCGATGTTTATATTGCTATTAGGAATTGGA
GTAGCATTACCTAACTGTTTAAGTTTAGCATTAGTAGATTTTCAAGATGTCATTGGTACAGCGGGTGCATTGTTTAGCCT
AGGGTACTATGTAATTGTAACGATAACAATTTGGGGAATGAGTCAACTTCATACGGGCTCGTTACTGGTGATGCCACTTT
ATTTTCTAGCTATAGTAGTTATCATGATGGTGTTTACTAAAGTGTTTGTTTTAGGTAAACAAACTTCAAAAACGATTTAA

Upstream 100 bases:

>100_bases
TTGTTTTATGAGCGAATTTCTATAATGGCCCCTCCTGTTCCGTAGCTAAGGAAAGTCTTTTTATTTCTGAGATTTTCAAA
GTTATAGGAGGGTATGAAAA

Downstream 100 bases:

>100_bases
ATATGAAATGGTAAAAGAGTCTCATTTTTTAATGAGACTCTTTTATATTTTATGAAAATGATTAGTGGATATACGAACAA
AAATTAAAGGTATTGTTGAT

Product: Bcr/CflA subfamily drug resistance transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRPAMLFGIV
VYGIGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTSSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFRL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMVVGAVALSLITSVGSNPNIIYMVGFLVAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTITIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFVLGKQTSKTI

Sequences:

>Translated_399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRPAMLFGIV
VYGIGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTSSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFRL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMVVGAVALSLITSVGSNPNIIYMVGFLVAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTITIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFVLGKQTSKTI
>Mature_399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRPAMLFGIV
VYGIGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTSSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFRL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMVVGAVALSLITSVGSNPNIIYMVGFLVAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTITIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFVLGKQTSKTI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=324, Percent_Identity=25.9259259259259, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788509, Length=233, Percent_Identity=29.1845493562232, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI87082312, Length=326, Percent_Identity=26.0736196319018, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790146, Length=191, Percent_Identity=26.7015706806283, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787065, Length=340, Percent_Identity=24.1176470588235, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790794, Length=388, Percent_Identity=23.9690721649485, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324264, Length=170, Percent_Identity=31.1764705882353, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43155; Mature: 43155

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA