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The map label for this gene is hpaX

Identifier: 30065589

GI number: 30065589

Start: 4542204

End: 4543559

Strand: Reverse

Name: hpaX

Synonym: S4648

Alternate gene names: 30065589

Gene position: 4543559-4542204 (Counterclockwise)

Preceding gene: 30065590

Following gene: 30065588

Centisome position: 98.79

GC content: 46.39

Gene sequence:

>1356_bases
ATGACGACCTCTACCCTGCAATATAAAGATAATAAAACTGTTGAAATTGAACATCGTGTCATTAATAAATTATTTCGTCG
CCTAATCATTTTTCTTTTTATTCTGTTTGTTTTTTCGTTTCTTGATCGCATCAATATAGGATTTGCCGGACTGACAATGG
GCAAGGATCTTGGCCTGACGTCCACAATGTTTGGCCTCGCCGCAACACTCTTTTATGTCACGTACGTCATGTGCGGGATC
CCCAGTAATATGATGTTAGCGAAAATTGGCGCTCGTCGATGGATCGCTGGGATCATGGTGGTCTGGGGAATTGCTTCCAC
CTGCACAATGTTTGCAACAAGCCCCGAAACACTCTATCTACTGCGTATGCTGGTTGGTATTGCTGAGGCGGGTTTTTTAC
CTGGTATTTTGGTTTATCTGACCTGGTGGTTCCCGGCATATCATCGGGCCAGAGCCAATGCCTTATTTATGATAGCGATG
CCAGTCACTATGATGCTGGGATTGATCCTTTCAGGCTACATTCTGGCCTTGGATGGACTGTGGAATCTAAAAGGCTGGCA
ATGGCTCTTTTTGCTGGAAGGTCTGCCATCGGTCATTCTTGGTGTCGTCACCTGGTTTTATCTCAACGACACACCAGACC
AGGCGACCTGGCTTGATGAAAACGAAAAACAGGCTTTAAAAACGATGATTCTCCGTGAACAAGAGAGTGCATTTGCCCAT
GCATCTGTTCCACGCTCAACCTTACGTGAAGTCCTGACCCCAGCCATCATGCTATATACACTTGCTTATTTTTGCCTGAC
TAATACTCTGAGTGCGATTAATATCTGGACGCCGCAAATCCTACAGAGTTTCAATACTGGCAGTAGCAACATCATGATTG
GTTTGCTGGCGGCCATCCCCCAATTCTGCACAATTTTTGGCATGATCTGGTGGAGTCGTCGTTCCGACCGTCTTAAAGAA
CGCAAAAAGCATACGATTCTTCCCTACCTGTTTGCCGCTGCCGGATGGTTACTCGCTTCTGCGACAGATCACAGCCTCAT
TCAACTGAGCAGCATCATTATGGCCTCAATGGGATCATTTACCGCGATGACTATCTTTTGGACAACACCGGATCAAGTTA
TAAGCTTGCAATCGCGTGCCGTTGCGATGGCTGTCATCAATGCTGTCGGCAATGTAGGTTCAGCAGTCAGTCCATTACTT
ATCGGTATTTTGAAAGATGCAACCGGCAGTTTTAGCTCAGGTTTGTGGTTTGTAGCAGGATTGCTGGTACTGGGCGCGTT
AGTCATGACCCGAATCCCTATGGGGAGTCGGGAACACTCTCTTTCATCTGAACTTATCGCACCAAAACCGCAATAA

Upstream 100 bases:

>100_bases
CGCCGAAGCGCTGGCAGCACGGTTTGGTAATAGTTCTTCTATTTCGATGGCGAAGCAAAACAACAACTCTGTCTACTAAA
CGTACGATGTGGAGCGCATC

Downstream 100 bases:

>100_bases
GGAGTCATGATGTCCAGTGAAGCTATCTTTGAACATGGTTATGAAAATATTGATTTGGTCCGGGAATATGATGCCCGCTA
CGCTGGTGAAGATGTGCATT

Product: putative 4-hydroxyphenylacetate permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTTSTLQYKDNKTVEIEHRVINKLFRRLIIFLFILFVFSFLDRINIGFAGLTMGKDLGLTSTMFGLAATLFYVTYVMCGI
PSNMMLAKIGARRWIAGIMVVWGIASTCTMFATSPETLYLLRMLVGIAEAGFLPGILVYLTWWFPAYHRARANALFMIAM
PVTMMLGLILSGYILALDGLWNLKGWQWLFLLEGLPSVILGVVTWFYLNDTPDQATWLDENEKQALKTMILREQESAFAH
ASVPRSTLREVLTPAIMLYTLAYFCLTNTLSAINIWTPQILQSFNTGSSNIMIGLLAAIPQFCTIFGMIWWSRRSDRLKE
RKKHTILPYLFAAAGWLLASATDHSLIQLSSIIMASMGSFTAMTIFWTTPDQVISLQSRAVAMAVINAVGNVGSAVSPLL
IGILKDATGSFSSGLWFVAGLLVLGALVMTRIPMGSREHSLSSELIAPKPQ

Sequences:

>Translated_451_residues
MTTSTLQYKDNKTVEIEHRVINKLFRRLIIFLFILFVFSFLDRINIGFAGLTMGKDLGLTSTMFGLAATLFYVTYVMCGI
PSNMMLAKIGARRWIAGIMVVWGIASTCTMFATSPETLYLLRMLVGIAEAGFLPGILVYLTWWFPAYHRARANALFMIAM
PVTMMLGLILSGYILALDGLWNLKGWQWLFLLEGLPSVILGVVTWFYLNDTPDQATWLDENEKQALKTMILREQESAFAH
ASVPRSTLREVLTPAIMLYTLAYFCLTNTLSAINIWTPQILQSFNTGSSNIMIGLLAAIPQFCTIFGMIWWSRRSDRLKE
RKKHTILPYLFAAAGWLLASATDHSLIQLSSIIMASMGSFTAMTIFWTTPDQVISLQSRAVAMAVINAVGNVGSAVSPLL
IGILKDATGSFSSGLWFVAGLLVLGALVMTRIPMGSREHSLSSELIAPKPQ
>Mature_450_residues
TTSTLQYKDNKTVEIEHRVINKLFRRLIIFLFILFVFSFLDRINIGFAGLTMGKDLGLTSTMFGLAATLFYVTYVMCGIP
SNMMLAKIGARRWIAGIMVVWGIASTCTMFATSPETLYLLRMLVGIAEAGFLPGILVYLTWWFPAYHRARANALFMIAMP
VTMMLGLILSGYILALDGLWNLKGWQWLFLLEGLPSVILGVVTWFYLNDTPDQATWLDENEKQALKTMILREQESAFAHA
SVPRSTLREVLTPAIMLYTLAYFCLTNTLSAINIWTPQILQSFNTGSSNIMIGLLAAIPQFCTIFGMIWWSRRSDRLKER
KKHTILPYLFAAAGWLLASATDHSLIQLSSIIMASMGSFTAMTIFWTTPDQVISLQSRAVAMAVINAVGNVGSAVSPLLI
GILKDATGSFSSGLWFVAGLLVLGALVMTRIPMGSREHSLSSELIAPKPQ

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=411, Percent_Identity=31.3868613138686, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1789515, Length=431, Percent_Identity=24.5939675174014, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1789152, Length=411, Percent_Identity=22.6277372262774, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87082320, Length=424, Percent_Identity=22.877358490566, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI2367379, Length=427, Percent_Identity=22.9508196721311, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322025, Length=264, Percent_Identity=25.7575757575758, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319876, Length=253, Percent_Identity=23.3201581027668, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321698, Length=326, Percent_Identity=25.1533742331288, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324410, Length=143, Percent_Identity=22.3776223776224, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50078; Mature: 49947

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSTLQYKDNKTVEIEHRVINKLFRRLIIFLFILFVFSFLDRINIGFAGLTMGKDLGLT
CCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHH
STMFGLAATLFYVTYVMCGIPSNMMLAKIGARRWIAGIMVVWGIASTCTMFATSPETLYL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LRMLVGIAEAGFLPGILVYLTWWFPAYHRARANALFMIAMPVTMMLGLILSGYILALDGL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCC
WNLKGWQWLFLLEGLPSVILGVVTWFYLNDTPDQATWLDENEKQALKTMILREQESAFAH
CCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ASVPRSTLREVLTPAIMLYTLAYFCLTNTLSAINIWTPQILQSFNTGSSNIMIGLLAAIP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHH
QFCTIFGMIWWSRRSDRLKERKKHTILPYLFAAAGWLLASATDHSLIQLSSIIMASMGSF
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
TAMTIFWTTPDQVISLQSRAVAMAVINAVGNVGSAVSPLLIGILKDATGSFSSGLWFVAG
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
LLVLGALVMTRIPMGSREHSLSSELIAPKPQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTSTLQYKDNKTVEIEHRVINKLFRRLIIFLFILFVFSFLDRINIGFAGLTMGKDLGLT
CCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHH
STMFGLAATLFYVTYVMCGIPSNMMLAKIGARRWIAGIMVVWGIASTCTMFATSPETLYL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LRMLVGIAEAGFLPGILVYLTWWFPAYHRARANALFMIAMPVTMMLGLILSGYILALDGL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCC
WNLKGWQWLFLLEGLPSVILGVVTWFYLNDTPDQATWLDENEKQALKTMILREQESAFAH
CCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ASVPRSTLREVLTPAIMLYTLAYFCLTNTLSAINIWTPQILQSFNTGSSNIMIGLLAAIP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHH
QFCTIFGMIWWSRRSDRLKERKKHTILPYLFAAAGWLLASATDHSLIQLSSIIMASMGSF
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
TAMTIFWTTPDQVISLQSRAVAMAVINAVGNVGSAVSPLLIGILKDATGSFSSGLWFVAG
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
LLVLGALVMTRIPMGSREHSLSSELIAPKPQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]