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The map label for this gene is ubiA

Identifier: 30064630

GI number: 30064630

Start: 3434864

End: 3435736

Strand: Direct

Name: ubiA

Synonym: S3566

Alternate gene names: 30064630

Gene position: 3434864-3435736 (Clockwise)

Preceding gene: 30064629

Following gene: 30064632

Centisome position: 74.68

GC content: 51.09

Gene sequence:

>873_bases
ATGGAGTGGAGTCTGACGCAGAATAAGCTGCTGGCGTTTCATCGCTTAATGCGTACGGATAAGCCAATTGGCGCGTTACT
GCTGCTCTGGCCAACATTATGGGCGTTGTGGGTGGCGACACCGGGCGTTCCTCAGCTCTGGATCATGGCGGTGTTTGTCG
CGGGTGTCTGGCTGATGCGCGCTGCTGGTTGCGTGGTGAATGATTATGCTGATCGCAAGTTTGATGGTCATGTTAAGCGC
ACGGCGAACCGACCACTTCCCAGCGGCGCGGTAACAGAGAAAGAGGCGCGCGCGCTGTTTGTAGTGCTGGTACTGATTTC
GTTTTTACTGGTTCTGACGCTGAATACGATGACCATTCTGTTGTCGATTGCCGCTCTGGCATTGGCGTGGGTGTACCCGT
TTATGAAGCGGTATACCCATCTCCCGCAAGTGGTGCTGGGCGCGGCGTTTGGCTGGTCGATTCCAATGGCTTTTGCCGCT
GTGAGTGAGTCGGTGCCATTGAGTTGCTGGTTAATGTTCCTCGCCAATATTCTCTGGGCGGTGGCTTACGACACGCAGTA
TGCGATGGTTGACCGCGATGATGATGTGAAGATTGGCATTAAATCCACGGCAATCCTGTTCGGCCAATACGATAAATTGA
TTATTGGTATTTTGCAGATTGGCGTACTGGCACTGATGGCGATCATCGGTGAGTTAAATGGCTTAGGCTGGGGATATTAC
TGGTCAATTGTGGTGGCTGGCGCGCTGTTTGTTTATCAACAAAAACTGATTGCCAACCGCGAGCGTGAAGCCTGCTTTAA
AGCATTTATGAATAATAACTATGTTGGTCTGGTACTGTTTTTAGGACTGGCAATGAGTTACTGGCATTTCTGA

Upstream 100 bases:

>100_bases
ACTGTGGGGGCGACGTTCCCGCCTGCGATTAAGCGGTAAACCGCTGTTGCTAACAGAACTGTTTTTACCGGCGTCACCGT
TGTACTAAGAGGAAAAAAAT

Downstream 100 bases:

>100_bases
TGATGTAAAAAAGCCGGATGATCATCCGGCTTTCTTCTGGGTTGCCTGATGCGTTGCGCTTCTCAGGCCTACCCGGTGAA
TCGCAATTTATTGAATTTGC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWIMAVFVAGVWLMRAAGCVVNDYADRKFDGHVKR
TANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYY
WSIVVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF

Sequences:

>Translated_290_residues
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWIMAVFVAGVWLMRAAGCVVNDYADRKFDGHVKR
TANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYY
WSIVVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
>Mature_290_residues
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWIMAVFVAGVWLMRAAGCVVNDYADRKFDGHVKR
TANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYY
WSIVVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=282, Percent_Identity=34.0425531914894, Blast_Score=174, Evalue=7e-44,
Organism=Escherichia coli, GI1790473, Length=290, Percent_Identity=99.3103448275862, Blast_Score=582, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI32565247, Length=281, Percent_Identity=36.6548042704626, Blast_Score=176, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17553718, Length=284, Percent_Identity=36.6197183098592, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17553720, Length=183, Percent_Identity=41.5300546448087, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=43.9716312056738, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32565243, Length=140, Percent_Identity=43.5714285714286, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324370, Length=300, Percent_Identity=31.6666666666667, Blast_Score=143, Evalue=3e-35,
Organism=Drosophila melanogaster, GI21355567, Length=276, Percent_Identity=36.9565217391304, Blast_Score=180, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32516; Mature: 32516

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWIMAVFVAGVWLMR
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTIL
HCCHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYY
HHHCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
WSIVVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWIMAVFVAGVWLMR
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTIL
HCCHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYY
HHHCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
WSIVVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA