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The map label for this gene is recG [H]

Identifier: 295815286

GI number: 295815286

Start: 2391123

End: 2392973

Strand: Direct

Name: recG [H]

Synonym: NA

Alternate gene names: 295815286

Gene position: 2391123-2392973 (Clockwise)

Preceding gene: 148359601

Following gene: 148359608

Centisome position: 66.86

GC content: 40.95

Gene sequence:

>1851_bases
ATGTTGAATTGTTATGTGGAAGATAAAACAGGAATAGTTAAGCTTCGTTTTTTTCATTTCAATAAGCAGCAAATTCAGGC
TTTGAATAATAGCGCCATGATTCGAGCTTTTGGCGAAGTCCGCGGATTTAACAACCAATTGGAGATGATTCATCCAGAAT
ATCAATTAATTGACCAAGAATCAGATTTCCACGTGGAAGAAACGCTTACGCCAATTTATCCATCGACTCAAGGCTTGACT
CAAACCCGATTAAGGCAGTTAGTTAAAATAGCCCTGGAACAATCTGAACACGAACTTCATCAATTGGAATGGATGAGTGA
AAAACAATTACAGGAAAACAATTTTTATGATTTGGGCGAAGCCATTAAATTACTACATAACCCTCCACCAGATATCTCCC
TCTCCAACCTCGAAGCCGGCGAACATCCTGCTCTCAAGCGGTTAATATTTGATGAATTACTGGCACAGCAGCTCAGTATG
CAATTTGCAAGACAGTCACGCAGCAAACTCCAAGCTCCCGCTATACTTTTCGATAATGCAATTCATAAACGTTTTATCGA
ATCATTGCCATTCAGTCTTACAAACGCACAACAACGGGTTTTTAAAGAAATCAGCGTTGATTTAACTCAAAGCAAACCCA
TGCTTCGTTTGCTGCAAGGAGATGTTGGGGCGGGTAAAACCATTATCGCGGCACTAGCCGCCCTTCAAGCCATTTCACAA
GGATTTCAGGTTGCTTTTATGGCACCAACCGATTTATTAAGTGAACAACATACAAATAGCCTCAGTAAATGGCTAGAACC
TATCGGTATTAATGTATTAAGACTGAGCGGTAAAATGAAAACCACAGAACGAAAAAATGCGCTTGCAGCCCTGCAGGACA
ATAGCTGTCAGCTCATTGTTGGAACTCATGCCTTATTTCAGGAGCAAGTCGAATTCGCTCGTTTGGGTTTGGTCATTATT
GACGAACAACACCGATTTGGAGTAGAACAACGGCTCCTTCTGCAACAAAAAGGGCAATTAAACCAATTAATCCCTCATCA
ATTATTAATGACAGCCACCCCTATTCCAAGAACCCTGTCAATGTCTCATTTTGCTCATTTGGATATATCGGTCATCGATG
AACTACCACCTGGCCGTATGCCAATTACAACAGCGGTATTGAACCAGGATAAGCGTGAACTCATTATCGAACGTTTGCAA
GCAGCAATCGCCAACGGCAAACAAGCTTACTGGGTCTGTACCCTTATAGAAGAATCTGAAAAATTACAATGCATAGCAGC
AACAGATACCTCAAAAAAATTACAAGAACAGCTCTCTTTCGCGCGTGTTCGTCAAGTTCATGGGAGAATGAAAGCGCATG
AAAAAGAAGCTACTATGGCGGCCTTTAAACAAGGCGAGATTGATAAAGTGGTGGCAACTACAGTTATTGAAGTTGGTGTA
GATGTTCCTAATGCCAGTTTAATGATCATTGAAAATGCGGAGCGACTTGGTTTGTCGCAGTTACATCAATTACGCGGGCG
CGTCGGCAGAGGTAATAATCAATCTCATTGTCTATTACTTTATCAATCTCCTCTATCACAGCAAGGTGCTGAACGTCTCA
AGATCATGCGTTCAACAACAGACGGTTTTCTAATCTCCGAAAAGGATTTGGAGTTAAGAGGCTCAGGAGAAATATTAGGA
ACCAGACAGACTGGCTTTAGACAATTTAAAATAGCTAACTTACAACGCGATAAAACCCTCTTCGCTATTTTACGTCCAAT
TGCAAAACAACTGATGCTGGAAAAAACAGCAATCGCCAGACAAATTACACAACGATGGCTGGGCAATTTTGAACAATTTT
TTCAAAGTTAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:
NA

Sequences:

>Translated_616_residues
MLNCYVEDKTGIVKLRFFHFNKQQIQALNNSAMIRAFGEVRGFNNQLEMIHPEYQLIDQESDFHVEETLTPIYPSTQGLT
QTRLRQLVKIALEQSEHELHQLEWMSEKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSM
QFARQSRSKLQAPAILFDNAIHKRFIESLPFSLTNAQQRVFKEISVDLTQSKPMLRLLQGDVGAGKTIIAALAALQAISQ
GFQVAFMAPTDLLSEQHTNSLSKWLEPIGINVLRLSGKMKTTERKNALAALQDNSCQLIVGTHALFQEQVEFARLGLVII
DEQHRFGVEQRLLLQQKGQLNQLIPHQLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQ
AAIANGKQAYWVCTLIEESEKLQCIAATDTSKKLQEQLSFARVRQVHGRMKAHEKEATMAAFKQGEIDKVVATTVIEVGV
DVPNASLMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLSQQGAERLKIMRSTTDGFLISEKDLELRGSGEILG
TRQTGFRQFKIANLQRDKTLFAILRPIAKQLMLEKTAIARQITQRWLGNFEQFFQS
>Mature_616_residues
MLNCYVEDKTGIVKLRFFHFNKQQIQALNNSAMIRAFGEVRGFNNQLEMIHPEYQLIDQESDFHVEETLTPIYPSTQGLT
QTRLRQLVKIALEQSEHELHQLEWMSEKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSM
QFARQSRSKLQAPAILFDNAIHKRFIESLPFSLTNAQQRVFKEISVDLTQSKPMLRLLQGDVGAGKTIIAALAALQAISQ
GFQVAFMAPTDLLSEQHTNSLSKWLEPIGINVLRLSGKMKTTERKNALAALQDNSCQLIVGTHALFQEQVEFARLGLVII
DEQHRFGVEQRLLLQQKGQLNQLIPHQLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQ
AAIANGKQAYWVCTLIEESEKLQCIAATDTSKKLQEQLSFARVRQVHGRMKAHEKEATMAAFKQGEIDKVVATTVIEVGV
DVPNASLMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLSQQGAERLKIMRSTTDGFLISEKDLELRGSGEILG
TRQTGFRQFKIANLQRDKTLFAILRPIAKQLMLEKTAIARQITQRWLGNFEQFFQS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=614, Percent_Identity=50.4885993485342, Blast_Score=589, Evalue=1e-169,
Organism=Escherichia coli, GI1787357, Length=404, Percent_Identity=35.1485148514851, Blast_Score=231, Evalue=7e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 69778; Mature: 69778

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNCYVEDKTGIVKLRFFHFNKQQIQALNNSAMIRAFGEVRGFNNQLEMIHPEYQLIDQE
CCEEEEECCCCEEEEEEEECCHHHHHHHCCCHHHHHHHHHCCCCCCCEEECCHHHHCCCC
SDFHVEETLTPIYPSTQGLTQTRLRQLVKIALEQSEHELHQLEWMSEKQLQENNFYDLGE
CCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
AIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQSRSKLQAPAILFDNA
HHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IHKRFIESLPFSLTNAQQRVFKEISVDLTQSKPMLRLLQGDVGAGKTIIAALAALQAISQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GFQVAFMAPTDLLSEQHTNSLSKWLEPIGINVLRLSGKMKTTERKNALAALQDNSCQLIV
CCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHEECCCCEEEEE
GTHALFQEQVEFARLGLVIIDEQHRFGVEQRLLLQQKGQLNQLIPHQLLMTATPIPRTLS
CHHHHHHHHHHHHHCCEEEEECHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHC
MSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAIANGKQAYWVCTLIEESE
HHHHHHCCHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
KLQCIAATDTSKKLQEQLSFARVRQVHGRMKAHEKEATMAAFKQGEIDKVVATTVIEVGV
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
DVPNASLMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLSQQGAERLKIMRSTT
CCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCC
DGFLISEKDLELRGSGEILGTRQTGFRQFKIANLQRDKTLFAILRPIAKQLMLEKTAIAR
CCEEEECCCCEECCCCCEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QITQRWLGNFEQFFQS
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNCYVEDKTGIVKLRFFHFNKQQIQALNNSAMIRAFGEVRGFNNQLEMIHPEYQLIDQE
CCEEEEECCCCEEEEEEEECCHHHHHHHCCCHHHHHHHHHCCCCCCCEEECCHHHHCCCC
SDFHVEETLTPIYPSTQGLTQTRLRQLVKIALEQSEHELHQLEWMSEKQLQENNFYDLGE
CCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
AIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQSRSKLQAPAILFDNA
HHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IHKRFIESLPFSLTNAQQRVFKEISVDLTQSKPMLRLLQGDVGAGKTIIAALAALQAISQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GFQVAFMAPTDLLSEQHTNSLSKWLEPIGINVLRLSGKMKTTERKNALAALQDNSCQLIV
CCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHEECCCCEEEEE
GTHALFQEQVEFARLGLVIIDEQHRFGVEQRLLLQQKGQLNQLIPHQLLMTATPIPRTLS
CHHHHHHHHHHHHHCCEEEEECHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHC
MSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAIANGKQAYWVCTLIEESE
HHHHHHCCHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
KLQCIAATDTSKKLQEQLSFARVRQVHGRMKAHEKEATMAAFKQGEIDKVVATTVIEVGV
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
DVPNASLMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLSQQGAERLKIMRSTT
CCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCC
DGFLISEKDLELRGSGEILGTRQTGFRQFKIANLQRDKTLFAILRPIAKQLMLEKTAIAR
CCEEEECCCCEECCCCCEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QITQRWLGNFEQFFQS
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]