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The map label for this gene is folB [H]

Identifier: 148359601

GI number: 148359601

Start: 2386750

End: 2387088

Strand: Direct

Name: folB [H]

Synonym: LPC_1513

Alternate gene names: 148359601

Gene position: 2386750-2387088 (Clockwise)

Preceding gene: 148359599

Following gene: 295815286

Centisome position: 66.73

GC content: 35.1

Gene sequence:

>339_bases
ATGGATACTTTAAATATTACAGCTCTCAGTGTTGAAACAAAAATTGGTGTTTATGGGTGGGAGCAGCGTATTAATCAACG
ATTATTAATTGATATATCCATTCCCTTTGACTTTAAAGATTGCAAAGATAATTTGTCTAATACACTGGATTACGCTGATT
TGTGCCAAACAGTAACTCAATTTGTAGAGTCAACTTCGTTTCAATTAATTGAAACGGTAGCGGAACAAATTGCACAATTA
ATCAAGCAAAAGTATCCTGTTAGTAAGGTTTCCGTCGCTGTTACAAAACCCCATGCTGTAAAAAACGCTGCGGGAATCCA
AGTAGTTGTAAACAGATAA

Upstream 100 bases:

>100_bases
ATAAGAAAGTTTAGATAAATTAAATGACTGAGTTAAAAAATTTTAAACAAAAAGATTGAGGATTTTTCGTAAGTCCTGAT
AAATTATTAATGGATATCAA

Downstream 100 bases:

>100_bases
TCTGAAAGAAGCAATCTTCTTTGATTAAATGATTACTCCTTATCCCCCAACGCTGCGCACCATGCCGTTCAGGTGCTCTG
TTTTGGCAAGGTTCATTTGA

Product: dihydroneopterin aldolase FolB

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 112; Mature: 112

Protein sequence:

>112_residues
MDTLNITALSVETKIGVYGWEQRINQRLLIDISIPFDFKDCKDNLSNTLDYADLCQTVTQFVESTSFQLIETVAEQIAQL
IKQKYPVSKVSVAVTKPHAVKNAAGIQVVVNR

Sequences:

>Translated_112_residues
MDTLNITALSVETKIGVYGWEQRINQRLLIDISIPFDFKDCKDNLSNTLDYADLCQTVTQFVESTSFQLIETVAEQIAQL
IKQKYPVSKVSVAVTKPHAVKNAAGIQVVVNR
>Mature_112_residues
MDTLNITALSVETKIGVYGWEQRINQRLLIDISIPFDFKDCKDNLSNTLDYADLCQTVTQFVESTSFQLIETVAEQIAQL
IKQKYPVSKVSVAVTKPHAVKNAAGIQVVVNR

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. Can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as substrates for the formation of 6-hydroxymethyldihydropterin, but it can also catalyze the epimeriza

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

Organism=Escherichia coli, GI87082204, Length=114, Percent_Identity=40.3508771929825, Blast_Score=92, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 12530; Mature: 12530

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLNITALSVETKIGVYGWEQRINQRLLIDISIPFDFKDCKDNLSNTLDYADLCQTVTQ
CCCCEEEEEEEECCCCCCCHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHH
FVESTSFQLIETVAEQIAQLIKQKYPVSKVSVAVTKPHAVKNAAGIQVVVNR
HHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCCCCEEEEEEC
>Mature Secondary Structure
MDTLNITALSVETKIGVYGWEQRINQRLLIDISIPFDFKDCKDNLSNTLDYADLCQTVTQ
CCCCEEEEEEEECCCCCCCHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHH
FVESTSFQLIETVAEQIAQLIKQKYPVSKVSVAVTKPHAVKNAAGIQVVVNR
HHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]