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The map label for this gene is atsA [H]

Identifier: 29350091

GI number: 29350091

Start: 6143443

End: 6145014

Strand: Reverse

Name: atsA [H]

Synonym: BT_4683

Alternate gene names: 29350091

Gene position: 6145014-6143443 (Counterclockwise)

Preceding gene: 29350092

Following gene: 29350090

Centisome position: 98.16

GC content: 45.04

Gene sequence:

>1572_bases
ATGATAAATAGAATAGTATATACTTCATTTTTATTAGGAGCGAGTTTCGCCAGTACAGAAGCACAGGTAAGTACTCCTCC
CAATATTGTATTGATTTTATGTGACGACATGGGATTCTCCGATCTGGGTTGCTACGGAAGTGAAATCCAGACTCCCAACA
TAGACCGTCTGGCAGAAAACGGGGTACGCTTCAGCCTGTTCAAAAATACAGGAAGAAGCTGCCCTAGCCGTGCTGCTTTG
CTGACAGGACATTATCAGCACGAAGCCGGCATGGGATGGATGACGGCAGTAGATGAACACCGCCCCGGATACAGAGGACA
AATTACAAAAAACATCCCCACCATTGCCGAGGTGATGAAAGCGAATGGCTACAGCACATATATGAGCGGTAAATGGCACG
TCACAGTGGACGGAGCTTTTGATACTCCCAATGGCAGCTATCCGGCCCAACGGGGATTTGACAAATATTACGGTTGCCTG
AGCGGAGGAGGCAGTTATTATAAACCAACACCGGTATACAGCAATCTGACCCGAATCAAAGAATTCCCCGATGACTATTA
CTATACCACTGCCATCACCGATTCCGCCGTCAGTTTTGTCAAGCAACACCCTACAGACAAACCGATGTTTATGTACGTAG
CTCATTATGCCCCTCACTTACCCCTCCAAGCTCCTGCCGATCGTGTAGAGAAATGCAGAGACCGATATAAAGTGGGATAT
GACATGTTGCGTAAACAACGTTTCGACAGGTTAAAGGAGCTGAAGTTCATTTCGGACGAAATGGATTATCCTGTCTACCA
AAAAGAATTTGACGGAAAACGTCCCTCTTGGGAAACACTCACACCAAAGCAACAGGAGCAATGGATTACCGATATGGCAA
CCTATGCCGCCATGATCGAAATTGTGGATAGCGGAATCGGTGAACTGGTGGAAACCATCAAGGAGAAAGGGATGCTGGAC
AATACCGTATTTATCTTCTTAAGCGATAACGGTGCAACCAAAGAAGGCGGATACCTGGGCCAGCTTATGGCTGATTTGAG
CAATACTCCTTATAGAAGCTATAAGTCACAATGTTTTCAGGGAGGCACAAGTACCCCTTTTATCTTATCTTATGGCGATG
CCGAAAAAAACAAGATGAAAGGTCAGATTTGCAGGCAACCTGCCCACATTATAGACATACTGCCTACCTGCATGGATATT
GCCACAGCTACTTATCCGTCAGAATTCAAAGAGAATTTGCCCGGCAAGAGCTTACTCCCTCCAATCCATGGAAAAAAGAT
AAAGCCCAGAGAATTATACTTTGAGCATCAAAGTTCCTGCGCCATTATTTCCAATCATTGGAAACTGGTACGCGGCAGCC
GGAATGAACCATGGGAGCTAATCGACTTATCGGCAGATCCGTTCGAAACCAAGGATTTGTCCGCCCAATATCCGAAGCTA
GTGAAAAAACTAGAGGCTAAATGGAATAAATGGGCGAAACAATGTAATGTCTTTCCACTCGAAAACAAACCTTGGACCGA
AAGAATTAACTACTATCTGAAACAAAATCCGGATCAAAGCGGAATAGAATAA

Upstream 100 bases:

>100_bases
CCTGAAACTGAAAGAAGTCGAAAAACAACAGAGTGACTTTGAATAATGCGCATAGTTCTATCTATAAACAGAAAAAACAC
AAACTTATTAAAATACAGTT

Downstream 100 bases:

>100_bases
AATCCGGGAACAATAGTCTTCTTAATACTAGGTTTAGAAAAAAGACTGTTCCTTTTAGACGAACAGTCTTTTTTCTGTTT
ACAAGACATATTGTTTGTAT

Product: arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MINRIVYTSFLLGASFASTEAQVSTPPNIVLILCDDMGFSDLGCYGSEIQTPNIDRLAENGVRFSLFKNTGRSCPSRAAL
LTGHYQHEAGMGWMTAVDEHRPGYRGQITKNIPTIAEVMKANGYSTYMSGKWHVTVDGAFDTPNGSYPAQRGFDKYYGCL
SGGGSYYKPTPVYSNLTRIKEFPDDYYYTTAITDSAVSFVKQHPTDKPMFMYVAHYAPHLPLQAPADRVEKCRDRYKVGY
DMLRKQRFDRLKELKFISDEMDYPVYQKEFDGKRPSWETLTPKQQEQWITDMATYAAMIEIVDSGIGELVETIKEKGMLD
NTVFIFLSDNGATKEGGYLGQLMADLSNTPYRSYKSQCFQGGTSTPFILSYGDAEKNKMKGQICRQPAHIIDILPTCMDI
ATATYPSEFKENLPGKSLLPPIHGKKIKPRELYFEHQSSCAIISNHWKLVRGSRNEPWELIDLSADPFETKDLSAQYPKL
VKKLEAKWNKWAKQCNVFPLENKPWTERINYYLKQNPDQSGIE

Sequences:

>Translated_523_residues
MINRIVYTSFLLGASFASTEAQVSTPPNIVLILCDDMGFSDLGCYGSEIQTPNIDRLAENGVRFSLFKNTGRSCPSRAAL
LTGHYQHEAGMGWMTAVDEHRPGYRGQITKNIPTIAEVMKANGYSTYMSGKWHVTVDGAFDTPNGSYPAQRGFDKYYGCL
SGGGSYYKPTPVYSNLTRIKEFPDDYYYTTAITDSAVSFVKQHPTDKPMFMYVAHYAPHLPLQAPADRVEKCRDRYKVGY
DMLRKQRFDRLKELKFISDEMDYPVYQKEFDGKRPSWETLTPKQQEQWITDMATYAAMIEIVDSGIGELVETIKEKGMLD
NTVFIFLSDNGATKEGGYLGQLMADLSNTPYRSYKSQCFQGGTSTPFILSYGDAEKNKMKGQICRQPAHIIDILPTCMDI
ATATYPSEFKENLPGKSLLPPIHGKKIKPRELYFEHQSSCAIISNHWKLVRGSRNEPWELIDLSADPFETKDLSAQYPKL
VKKLEAKWNKWAKQCNVFPLENKPWTERINYYLKQNPDQSGIE
>Mature_523_residues
MINRIVYTSFLLGASFASTEAQVSTPPNIVLILCDDMGFSDLGCYGSEIQTPNIDRLAENGVRFSLFKNTGRSCPSRAAL
LTGHYQHEAGMGWMTAVDEHRPGYRGQITKNIPTIAEVMKANGYSTYMSGKWHVTVDGAFDTPNGSYPAQRGFDKYYGCL
SGGGSYYKPTPVYSNLTRIKEFPDDYYYTTAITDSAVSFVKQHPTDKPMFMYVAHYAPHLPLQAPADRVEKCRDRYKVGY
DMLRKQRFDRLKELKFISDEMDYPVYQKEFDGKRPSWETLTPKQQEQWITDMATYAAMIEIVDSGIGELVETIKEKGMLD
NTVFIFLSDNGATKEGGYLGQLMADLSNTPYRSYKSQCFQGGTSTPFILSYGDAEKNKMKGQICRQPAHIIDILPTCMDI
ATATYPSEFKENLPGKSLLPPIHGKKIKPRELYFEHQSSCAIISNHWKLVRGSRNEPWELIDLSADPFETKDLSAQYPKL
VKKLEAKWNKWAKQCNVFPLENKPWTERINYYLKQNPDQSGIE

Specific function: Plays an important role in the mineralization of sulfates [H]

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI38569405, Length=539, Percent_Identity=27.2727272727273, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI109389362, Length=550, Percent_Identity=25.8181818181818, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI38569407, Length=398, Percent_Identity=29.3969849246231, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI59797060, Length=522, Percent_Identity=26.4367816091954, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI53831991, Length=479, Percent_Identity=26.7223382045929, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI146229331, Length=481, Percent_Identity=28.0665280665281, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI146229329, Length=481, Percent_Identity=28.0665280665281, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI6005990, Length=481, Percent_Identity=28.0665280665281, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI146229324, Length=481, Percent_Identity=28.0665280665281, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI58743319, Length=566, Percent_Identity=24.0282685512367, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI157266309, Length=160, Percent_Identity=36.25, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI71852586, Length=142, Percent_Identity=40.8450704225352, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI71852584, Length=142, Percent_Identity=40.8450704225352, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI31742482, Length=138, Percent_Identity=40.5797101449275, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4503899, Length=241, Percent_Identity=33.6099585062241, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI45430057, Length=284, Percent_Identity=29.9295774647887, Blast_Score=96, Evalue=8e-20,
Organism=Escherichia coli, GI87081924, Length=459, Percent_Identity=25.9259259259259, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1790112, Length=469, Percent_Identity=25.7995735607676, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790233, Length=453, Percent_Identity=23.6203090507726, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115533416, Length=505, Percent_Identity=25.3465346534653, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI115533418, Length=490, Percent_Identity=25.1020408163265, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17559078, Length=130, Percent_Identity=34.6153846153846, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24666175, Length=446, Percent_Identity=29.372197309417, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI281366397, Length=476, Percent_Identity=26.6806722689076, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281366395, Length=476, Percent_Identity=26.6806722689076, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24666163, Length=476, Percent_Identity=26.6806722689076, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281363223, Length=452, Percent_Identity=27.8761061946903, Blast_Score=145, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24666109, Length=461, Percent_Identity=28.1995661605206, Blast_Score=139, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 59422; Mature: 59422

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINRIVYTSFLLGASFASTEAQVSTPPNIVLILCDDMGFSDLGCYGSEIQTPNIDRLAEN
CCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHC
GVRFSLFKNTGRSCPSRAALLTGHYQHEAGMGWMTAVDEHRPGYRGQITKNIPTIAEVMK
CCEEEEECCCCCCCCCCHHHHCCCHHHHCCCCHHHHHHHCCCCCCCEECCCCHHHHHHHH
ANGYSTYMSGKWHVTVDGAFDTPNGSYPAQRGFDKYYGCLSGGGSYYKPTPVYSNLTRIK
CCCCEEEECCEEEEEECCCCCCCCCCCCHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHH
EFPDDYYYTTAITDSAVSFVKQHPTDKPMFMYVAHYAPHLPLQAPADRVEKCRDRYKVGY
HCCCCEEEEEEHHHHHHHHHHHCCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHHHHHHH
DMLRKQRFDRLKELKFISDEMDYPVYQKEFDGKRPSWETLTPKQQEQWITDMATYAAMIE
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IVDSGIGELVETIKEKGMLDNTVFIFLSDNGATKEGGYLGQLMADLSNTPYRSYKSQCFQ
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHC
GGTSTPFILSYGDAEKNKMKGQICRQPAHIIDILPTCMDIATATYPSEFKENLPGKSLLP
CCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCC
PIHGKKIKPRELYFEHQSSCAIISNHWKLVRGSRNEPWELIDLSADPFETKDLSAQYPKL
CCCCCCCCHHHHHHHCCCCEEEEECCCCEEECCCCCCCEEEECCCCCCCCCCCCHHHHHH
VKKLEAKWNKWAKQCNVFPLENKPWTERINYYLKQNPDQSGIE
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MINRIVYTSFLLGASFASTEAQVSTPPNIVLILCDDMGFSDLGCYGSEIQTPNIDRLAEN
CCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHC
GVRFSLFKNTGRSCPSRAALLTGHYQHEAGMGWMTAVDEHRPGYRGQITKNIPTIAEVMK
CCEEEEECCCCCCCCCCHHHHCCCHHHHCCCCHHHHHHHCCCCCCCEECCCCHHHHHHHH
ANGYSTYMSGKWHVTVDGAFDTPNGSYPAQRGFDKYYGCLSGGGSYYKPTPVYSNLTRIK
CCCCEEEECCEEEEEECCCCCCCCCCCCHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHH
EFPDDYYYTTAITDSAVSFVKQHPTDKPMFMYVAHYAPHLPLQAPADRVEKCRDRYKVGY
HCCCCEEEEEEHHHHHHHHHHHCCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHHHHHHH
DMLRKQRFDRLKELKFISDEMDYPVYQKEFDGKRPSWETLTPKQQEQWITDMATYAAMIE
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IVDSGIGELVETIKEKGMLDNTVFIFLSDNGATKEGGYLGQLMADLSNTPYRSYKSQCFQ
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHC
GGTSTPFILSYGDAEKNKMKGQICRQPAHIIDILPTCMDIATATYPSEFKENLPGKSLLP
CCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCC
PIHGKKIKPRELYFEHQSSCAIISNHWKLVRGSRNEPWELIDLSADPFETKDLSAQYPKL
CCCCCCCCHHHHHHHCCCCEEEEECCCCEEECCCCCCCEEEECCCCCCCCCCCCHHHHHH
VKKLEAKWNKWAKQCNVFPLENKPWTERINYYLKQNPDQSGIE
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10336424 [H]