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The map label for this gene is yehU [C]

Identifier: 29349975

GI number: 29349975

Start: 5987249

End: 5988289

Strand: Reverse

Name: yehU [C]

Synonym: BT_4567

Alternate gene names: 29349975

Gene position: 5988289-5987249 (Counterclockwise)

Preceding gene: 29349976

Following gene: 29349974

Centisome position: 95.65

GC content: 36.79

Gene sequence:

>1041_bases
ATGAACTTAAAGTACGAATGGATTAACACCCTATTTATAATACTGCCACTTTCCTTGTGCGTATTTATTATTGTAGATAT
CGCTTATAATGAGCGAATATGGGAACTGGATACTTTTGCCGTAAAAGCACGTTTACAGGCATTGGGCATCACTGTTGCTT
ACTTCTATCTTTTAAACTATATTTTTAAGCGGGTAGCCCGCTTCTTTATCGACAAAAGCAAAGATGAGAAGAAAGCAAAC
TGGAAAGAATACGTATGGGTGTTTCTGATAAACTTCGTCTTCCTAAATATCATGCATACATTCATTATGTTTTGCATAAC
GATGGCCGGGACTTTCAAATGGGGCGAATCGGCATTGATCAATGTGACAGGAGCTCTCCTGGCGTTTCTATATTATATAA
TGATACGCAATAGAATTTTATTCAAGAGTCTTATCGAGCAAAGCCTTCAATTAGAAAAAGTAAAAGTCGACCAACTGGAG
ACCGAACTTAAATTTCTGAAATCCCAATATCATCCGCATTTCCTGTTCAATGCTTTAAATACCATCTATTTTCAAGTGGA
TGAGAATAACAAAGTAGCCAAACAAAGTATCGAGCAGCTCTCCGACCTGTTGCGATATCAGCTTTATGATATAGAAAAGG
AAGTGACGATGGAACAGGAAATAAATTACCTGAGATCATATATTGCCTTTCAGCAATTGCGGATGAGCGAAAGGCTTATG
TTGGATTTATATTTCGACCCGCAACTAAAAGAGCAAAAAATACATCCTTTATTACTTCAGCCACTGATCGAGAATGCTTT
CAAATACGTAAGAGGAGATTACAAAATAAAACTGGAAATCAAAGTTGACGGAAACCAGATTCAGTCTGAGATAAAAAATT
CAATATCCTCCTCCCCATCTACTGCCAACAAAAAAGAGAAAGGGATAGGCATTGAGAATTTAAAACGCCGGCTTGACCTT
CTGTATCCTGAAAAATACAGCTTAGACTTCAAACAAACAGACCATATGTTTATCGCTAAATTAACCATAAACACTGATTG
A

Upstream 100 bases:

>100_bases
TTTCAATCGAGGCAAAGAGATTAAGAAATCTCAGAATGAAAACAGAATAGAAGAAAGTAAACGGATAGGTTTGTAGTATC
AAAGATTAAAATAGCAACTA

Downstream 100 bases:

>100_bases
TATGAAAATAAAATGTATCATTACAGATGATGAACCTATAGCAAGAAAAGGCTTGCGAGGGTATATCGAAAAAGTAGATT
TCCTCACCTTGACCGGAGAG

Product: two-component system sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNLKYEWINTLFIILPLSLCVFIIVDIAYNERIWELDTFAVKARLQALGITVAYFYLLNYIFKRVARFFIDKSKDEKKAN
WKEYVWVFLINFVFLNIMHTFIMFCITMAGTFKWGESALINVTGALLAFLYYIMIRNRILFKSLIEQSLQLEKVKVDQLE
TELKFLKSQYHPHFLFNALNTIYFQVDENNKVAKQSIEQLSDLLRYQLYDIEKEVTMEQEINYLRSYIAFQQLRMSERLM
LDLYFDPQLKEQKIHPLLLQPLIENAFKYVRGDYKIKLEIKVDGNQIQSEIKNSISSSPSTANKKEKGIGIENLKRRLDL
LYPEKYSLDFKQTDHMFIAKLTINTD

Sequences:

>Translated_346_residues
MNLKYEWINTLFIILPLSLCVFIIVDIAYNERIWELDTFAVKARLQALGITVAYFYLLNYIFKRVARFFIDKSKDEKKAN
WKEYVWVFLINFVFLNIMHTFIMFCITMAGTFKWGESALINVTGALLAFLYYIMIRNRILFKSLIEQSLQLEKVKVDQLE
TELKFLKSQYHPHFLFNALNTIYFQVDENNKVAKQSIEQLSDLLRYQLYDIEKEVTMEQEINYLRSYIAFQQLRMSERLM
LDLYFDPQLKEQKIHPLLLQPLIENAFKYVRGDYKIKLEIKVDGNQIQSEIKNSISSSPSTANKKEKGIGIENLKRRLDL
LYPEKYSLDFKQTDHMFIAKLTINTD
>Mature_346_residues
MNLKYEWINTLFIILPLSLCVFIIVDIAYNERIWELDTFAVKARLQALGITVAYFYLLNYIFKRVARFFIDKSKDEKKAN
WKEYVWVFLINFVFLNIMHTFIMFCITMAGTFKWGESALINVTGALLAFLYYIMIRNRILFKSLIEQSLQLEKVKVDQLE
TELKFLKSQYHPHFLFNALNTIYFQVDENNKVAKQSIEQLSDLLRYQLYDIEKEVTMEQEINYLRSYIAFQQLRMSERLM
LDLYFDPQLKEQKIHPLLLQPLIENAFKYVRGDYKIKLEIKVDGNQIQSEIKNSISSSPSTANKKEKGIGIENLKRRLDL
LYPEKYSLDFKQTDHMFIAKLTINTD

Specific function: Probable member of the two-component regulatory system SE_0166/SE_0165. May activate SE_0165 by phosphorylation [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=184, Percent_Identity=27.1739130434783, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788723, Length=195, Percent_Identity=31.2820512820513, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR010559 [H]

Pfam domain/function: PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41180; Mature: 41180

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKYEWINTLFIILPLSLCVFIIVDIAYNERIWELDTFAVKARLQALGITVAYFYLLNY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
IFKRVARFFIDKSKDEKKANWKEYVWVFLINFVFLNIMHTFIMFCITMAGTFKWGESALI
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
NVTGALLAFLYYIMIRNRILFKSLIEQSLQLEKVKVDQLETELKFLKSQYHPHFLFNALN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TIYFQVDENNKVAKQSIEQLSDLLRYQLYDIEKEVTMEQEINYLRSYIAFQQLRMSERLM
HEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LDLYFDPQLKEQKIHPLLLQPLIENAFKYVRGDYKIKLEIKVDGNQIQSEIKNSISSSPS
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHCCCCC
TANKKEKGIGIENLKRRLDLLYPEKYSLDFKQTDHMFIAKLTINTD
CCCCHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MNLKYEWINTLFIILPLSLCVFIIVDIAYNERIWELDTFAVKARLQALGITVAYFYLLNY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
IFKRVARFFIDKSKDEKKANWKEYVWVFLINFVFLNIMHTFIMFCITMAGTFKWGESALI
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
NVTGALLAFLYYIMIRNRILFKSLIEQSLQLEKVKVDQLETELKFLKSQYHPHFLFNALN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TIYFQVDENNKVAKQSIEQLSDLLRYQLYDIEKEVTMEQEINYLRSYIAFQQLRMSERLM
HEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LDLYFDPQLKEQKIHPLLLQPLIENAFKYVRGDYKIKLEIKVDGNQIQSEIKNSISSSPS
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHCCCCC
TANKKEKGIGIENLKRRLDLLYPEKYSLDFKQTDHMFIAKLTINTD
CCCCHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]