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The map label for this gene is cutC

Identifier: 29349824

GI number: 29349824

Start: 5819609

End: 5820358

Strand: Reverse

Name: cutC

Synonym: BT_4416

Alternate gene names: 29349824

Gene position: 5820358-5819609 (Counterclockwise)

Preceding gene: 29349825

Following gene: 29349816

Centisome position: 92.97

GC content: 48.27

Gene sequence:

>750_bases
ATGAAAAAGTACCAATTTGAAGTCTGTGCCAATTCCGTAGAAAGCTGTCTGGCAGCACAGGCAGGCGGAGCCGACCGGGT
AGAGTTATGTGCAGGTATTCCGGAAGGCGGGACGACTCCTTCTTACGGAGAGATATCGACAGCACGCGACATGCTGACAA
CGACTCGTCTGCATGTCATTATCCGTCCGCGGGGTGGGGATTTTCTTTATTCTCCCATCGAAGTGAGAACGATGCTGAAA
GATATAGAAATGGCACGGCAGTTGGGAGCTGACGGAGTGGTATTCGGTTGTCTGACGGCAAACGGGGAAATCGACCTTCC
TGTAATGCAAGAGTTAATGAAAGCCTCACAAGGGTTATCAGTGACTTTTCACCGTGCTTTTGATATATGCCGTGATCCTG
AAAAGGCTTTGGAGCAGATTATCGAACTGGGGTGTAACCGTATCCTTACTTCCGGTCAGCAAGCTACTGCCGAACTCGGA
ATCCCCTTGCTAAAAGCATTGCAGACACAGGCTTCCGGAAGAATTATCCTGCTTGCCGGATGTGGCGTGAACGAAAAAAA
TATCGCCCGCATTGCTTCGGAAACCGGAATACAGGAGTTTCATTTCTCCGCACGGGAAAGCATCAAGAGCGATATGAAGT
ATAAAAACGAATCAGTATCGATGGGCGGCACTGTACATATCGACGAATACGAACGAAATGTAACCACCGCCCAAAGAGTG
ATAAATACCATTCAGGCTATAAAAAGCTGA

Upstream 100 bases:

>100_bases
AATACAAGGGCGAAGCAATTCGCCCTTTTTCAATTTATCATCATTCACTTCTCATGTTTGCAGCATCACGCAGCAGCATA
CAGTCTAAAAGTATCAGCTT

Downstream 100 bases:

>100_bases
AAACTGCGATAAACAGCGATTTATAGTCCTGCAATAGCATACCTGTTTATAAATAAGGGATAATCGTAATATAAATACCG
GTAATAATAGCCGAGGTGAT

Product: Cu2+ homeostasis protein CutC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKKYQFEVCANSVESCLAAQAGGADRVELCAGIPEGGTTPSYGEISTARDMLTTTRLHVIIRPRGGDFLYSPIEVRTMLK
DIEMARQLGADGVVFGCLTANGEIDLPVMQELMKASQGLSVTFHRAFDICRDPEKALEQIIELGCNRILTSGQQATAELG
IPLLKALQTQASGRIILLAGCGVNEKNIARIASETGIQEFHFSARESIKSDMKYKNESVSMGGTVHIDEYERNVTTAQRV
INTIQAIKS

Sequences:

>Translated_249_residues
MKKYQFEVCANSVESCLAAQAGGADRVELCAGIPEGGTTPSYGEISTARDMLTTTRLHVIIRPRGGDFLYSPIEVRTMLK
DIEMARQLGADGVVFGCLTANGEIDLPVMQELMKASQGLSVTFHRAFDICRDPEKALEQIIELGCNRILTSGQQATAELG
IPLLKALQTQASGRIILLAGCGVNEKNIARIASETGIQEFHFSARESIKSDMKYKNESVSMGGTVHIDEYERNVTTAQRV
INTIQAIKS
>Mature_249_residues
MKKYQFEVCANSVESCLAAQAGGADRVELCAGIPEGGTTPSYGEISTARDMLTTTRLHVIIRPRGGDFLYSPIEVRTMLK
DIEMARQLGADGVVFGCLTANGEIDLPVMQELMKASQGLSVTFHRAFDICRDPEKALEQIIELGCNRILTSGQQATAELG
IPLLKALQTQASGRIILLAGCGVNEKNIARIASETGIQEFHFSARESIKSDMKYKNESVSMGGTVHIDEYERNVTTAQRV
INTIQAIKS

Specific function: Involved in copper homeostasis

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family

Homologues:

Organism=Homo sapiens, GI148596990, Length=244, Percent_Identity=47.5409836065574, Blast_Score=228, Evalue=5e-60,
Organism=Escherichia coli, GI87081995, Length=235, Percent_Identity=42.9787234042553, Blast_Score=187, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17556905, Length=221, Percent_Identity=38.0090497737557, Blast_Score=158, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21355415, Length=253, Percent_Identity=34.3873517786561, Blast_Score=146, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CUTC_BACTN (Q89ZG1)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_813327.1
- ProteinModelPortal:   Q89ZG1
- SMR:   Q89ZG1
- GeneID:   1074820
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_4416
- NMPDR:   fig|226186.1.peg.4414
- HOGENOM:   HBG535337
- OMA:   PVYAMIR
- PhylomeDB:   Q89ZG1
- ProtClustDB:   CLSK2391384
- BioCyc:   BTHE226186:BT_4416-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00795
- InterPro:   IPR005627
- Gene3D:   G3DSA:3.20.20.380
- PANTHER:   PTHR12598

Pfam domain/function: PF03932 CutC; SSF110395 CutC

EC number: NA

Molecular weight: Translated: 27071; Mature: 27071

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYQFEVCANSVESCLAAQAGGADRVELCAGIPEGGTTPSYGEISTARDMLTTTRLHVI
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEEEEEE
IRPRGGDFLYSPIEVRTMLKDIEMARQLGADGVVFGCLTANGEIDLPVMQELMKASQGLS
EEECCCCEEECHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCE
VTFHRAFDICRDPEKALEQIIELGCNRILTSGQQATAELGIPLLKALQTQASGRIILLAG
EEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHCCCCCEEEEEC
CGVNEKNIARIASETGIQEFHFSARESIKSDMKYKNESVSMGGTVHIDEYERNVTTAQRV
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHH
INTIQAIKS
HHHHHHHCC
>Mature Secondary Structure
MKKYQFEVCANSVESCLAAQAGGADRVELCAGIPEGGTTPSYGEISTARDMLTTTRLHVI
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEEEEEE
IRPRGGDFLYSPIEVRTMLKDIEMARQLGADGVVFGCLTANGEIDLPVMQELMKASQGLS
EEECCCCEEECHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCE
VTFHRAFDICRDPEKALEQIIELGCNRILTSGQQATAELGIPLLKALQTQASGRIILLAG
EEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHCCCCCEEEEEC
CGVNEKNIARIASETGIQEFHFSARESIKSDMKYKNESVSMGGTVHIDEYERNVTTAQRV
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHH
INTIQAIKS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928