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The map label for this gene is hex20 [H]

Identifier: 29349276

GI number: 29349276

Start: 5039698

End: 5041683

Strand: Reverse

Name: hex20 [H]

Synonym: BT_3868

Alternate gene names: 29349276

Gene position: 5041683-5039698 (Counterclockwise)

Preceding gene: 29349287

Following gene: 29349275

Centisome position: 80.53

GC content: 47.89

Gene sequence:

>1986_bases
ATGAGAAACAAGTTTGTATCTTTGCAAGCTCTGGCCTTATTGGTCATCTTTTGTCTGACGGGTAGCTTAACCCGTGCCGC
TGTCAACCCGAAACCGTTTGTTGTCCCCGAACTCAAACAATGGACGGGAAAAGACGGTAACTTCACTCCGGGAAAAGACA
CCCGAATCGTCTGCACTTCCCAAAATCCCGAATTACTGAGAATAGCCCGGATGTTCGCCGACGATTATCAACAGATGTTC
GGGCAGACATTAAGCGTAGCACAAGGCAAAGCCACGTCCGGCGATTTCGTCCTATCCTTGTCGGCAGACAAGAAGCTCGG
TGAGGAAGGTTACGCCATCAAGATAACCGACCGTGTAGCCATCTCCGCTCCCACCCCGACCGGTCTTTACTGGAGCACAC
GCACACTCCTGCAACTGGCGGAACAAAATCAGGAACGCTCACTCCCGCAAGGAACGATTCGTGATTATCCCGATTATCCG
CTTCGCGGTTTCATGATAGACTGTGGCCGTAAGTTCATTCCGATGGCTTATCTGCAGGACTTGGTGAAAATCATGGCTTA
CTACAAAATGAACACCCTGCAAGTCCATCTGAACGATAATGGATTCAAGCAATACTTCGAACACAACTGGGACAAGACTT
ACGCTGCCTTCCGGCTGGAATCGGAGACTTATCCGGGATTGACAGCCCGTGACGGCTCGTACTCCAAGAAAGAATTCATC
GATTTCCAGAAACAAGCGGCATCCAACTTCGTGGAAATCATTCCGGAAATTGACGTTCCCGCCCACTCACTGGCTCTCAC
CCATTACAAACCGGAAATCGGAAGCAAGGAGTACGGCATGGATCACCTTGACTTATTCAAGCCGGAAACTTACGAATTCG
TAGATGCTCTGTTCAAAGAATATCTGGAGGGCGACAATCCGGTATTCGTAGGCAAGCGTGTACATATCGGTACAGACGAA
TACTCGAACGCGAAGAAAGACGTGGTAGAAAAATTCCGTGCTTTCACCGACCATTACATCCGTTTTGTGGAAGGTTTCGG
CAAGCAAGCAGTCGTATGGGGCGCGCTCAGCCATGCCAAAGGCGATACGCCCGTCAAATCAGAAAATGTCGTCATGAATG
CTTGGTACAACGGATACGCCGATCCGGCAACTATGATCAAAGACGGATATCAACTGATCAGTATTCCGGACGGACTGGTA
TATATCGTTCCGAAAGCCGGCTACTATTATGATTACCTCAACGAACCATACTTATATAAGGAGTGGACACCCGCCCATAT
CGGCAAAGCTGTATTCGACGAAAAACATCCTTCCATTCTTGGCGGTATGTTTGCCATCTGGAACGACCATGTCGGCAACG
GTATCTCGGTGAAAGACATCCATCACCGTATATTCTCGCCCCTGCAAACACTCTCTGTAAAGATGTGGACAGGCGCTCAA
ACGGGCATTCCTTATGAAACATTCAATGAAAAACGTGCCCTCCTCAGCGAAGCGCCCGGAGTCAACCAACTGGCAAGAAT
CGGCAAAAAGCCGGAATTGGTATACGAACGTTCCACAGTCGCTCCCGGCAGCACTTCCGATTATCCGGAAATTGGCTATA
ATTACACTGTCAGTTTCGACATTACCGGAGCAAAAGAAAGTGAAGGAACCGAATTGTTCCGTTCGCCTAACGCCGTATTC
TATCTGTCAGACCCTATTCGGGGGATGATGGGATTTGCACGCGACGGCTATCTGAATACCTTCCCCTACAAAGTGAATCC
GGGAGAAAAAGCAACAATTCAGATAGAAGGAAACAATCGCAGCACAACGCTGAGAGTCAACGGTAAAGTGGTTGATGAAA
TGAATACGCAGAAACTTTACTTTAATGCGGGAAAAGATTCAATGAACTATGTACGTACACTAGTTTTCCCGCTGGAGAAA
GCAGGAAACTTTAATAGTAAGGTACAGAATCTGAAAGTATACAATTATTGCGTAAGCAAACCATAA

Upstream 100 bases:

>100_bases
AATAGCTTCACTTGTTGACAGATATCCAAATTATGCCTACTTTCAGCCAATAATTAACTATAATCATTTATTAATTAACA
AAAACACAAAAATCCCCCTT

Downstream 100 bases:

>100_bases
GATTTAGATACGGATTACACAGATTTCACATTTTTTTAGCGGTACAATCTACCAAAAACCGTATCAATCTGTGTAATCCG
CTTCTGGAAGAAGCACAATC

Product: glycosyl hydrolase

Products: NA

Alternate protein names: Beta-N-acetylgalactosaminidase; Beta-N-acetylglucosaminidase; Hex20 [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MRNKFVSLQALALLVIFCLTGSLTRAAVNPKPFVVPELKQWTGKDGNFTPGKDTRIVCTSQNPELLRIARMFADDYQQMF
GQTLSVAQGKATSGDFVLSLSADKKLGEEGYAIKITDRVAISAPTPTGLYWSTRTLLQLAEQNQERSLPQGTIRDYPDYP
LRGFMIDCGRKFIPMAYLQDLVKIMAYYKMNTLQVHLNDNGFKQYFEHNWDKTYAAFRLESETYPGLTARDGSYSKKEFI
DFQKQAASNFVEIIPEIDVPAHSLALTHYKPEIGSKEYGMDHLDLFKPETYEFVDALFKEYLEGDNPVFVGKRVHIGTDE
YSNAKKDVVEKFRAFTDHYIRFVEGFGKQAVVWGALSHAKGDTPVKSENVVMNAWYNGYADPATMIKDGYQLISIPDGLV
YIVPKAGYYYDYLNEPYLYKEWTPAHIGKAVFDEKHPSILGGMFAIWNDHVGNGISVKDIHHRIFSPLQTLSVKMWTGAQ
TGIPYETFNEKRALLSEAPGVNQLARIGKKPELVYERSTVAPGSTSDYPEIGYNYTVSFDITGAKESEGTELFRSPNAVF
YLSDPIRGMMGFARDGYLNTFPYKVNPGEKATIQIEGNNRSTTLRVNGKVVDEMNTQKLYFNAGKDSMNYVRTLVFPLEK
AGNFNSKVQNLKVYNYCVSKP

Sequences:

>Translated_661_residues
MRNKFVSLQALALLVIFCLTGSLTRAAVNPKPFVVPELKQWTGKDGNFTPGKDTRIVCTSQNPELLRIARMFADDYQQMF
GQTLSVAQGKATSGDFVLSLSADKKLGEEGYAIKITDRVAISAPTPTGLYWSTRTLLQLAEQNQERSLPQGTIRDYPDYP
LRGFMIDCGRKFIPMAYLQDLVKIMAYYKMNTLQVHLNDNGFKQYFEHNWDKTYAAFRLESETYPGLTARDGSYSKKEFI
DFQKQAASNFVEIIPEIDVPAHSLALTHYKPEIGSKEYGMDHLDLFKPETYEFVDALFKEYLEGDNPVFVGKRVHIGTDE
YSNAKKDVVEKFRAFTDHYIRFVEGFGKQAVVWGALSHAKGDTPVKSENVVMNAWYNGYADPATMIKDGYQLISIPDGLV
YIVPKAGYYYDYLNEPYLYKEWTPAHIGKAVFDEKHPSILGGMFAIWNDHVGNGISVKDIHHRIFSPLQTLSVKMWTGAQ
TGIPYETFNEKRALLSEAPGVNQLARIGKKPELVYERSTVAPGSTSDYPEIGYNYTVSFDITGAKESEGTELFRSPNAVF
YLSDPIRGMMGFARDGYLNTFPYKVNPGEKATIQIEGNNRSTTLRVNGKVVDEMNTQKLYFNAGKDSMNYVRTLVFPLEK
AGNFNSKVQNLKVYNYCVSKP
>Mature_661_residues
MRNKFVSLQALALLVIFCLTGSLTRAAVNPKPFVVPELKQWTGKDGNFTPGKDTRIVCTSQNPELLRIARMFADDYQQMF
GQTLSVAQGKATSGDFVLSLSADKKLGEEGYAIKITDRVAISAPTPTGLYWSTRTLLQLAEQNQERSLPQGTIRDYPDYP
LRGFMIDCGRKFIPMAYLQDLVKIMAYYKMNTLQVHLNDNGFKQYFEHNWDKTYAAFRLESETYPGLTARDGSYSKKEFI
DFQKQAASNFVEIIPEIDVPAHSLALTHYKPEIGSKEYGMDHLDLFKPETYEFVDALFKEYLEGDNPVFVGKRVHIGTDE
YSNAKKDVVEKFRAFTDHYIRFVEGFGKQAVVWGALSHAKGDTPVKSENVVMNAWYNGYADPATMIKDGYQLISIPDGLV
YIVPKAGYYYDYLNEPYLYKEWTPAHIGKAVFDEKHPSILGGMFAIWNDHVGNGISVKDIHHRIFSPLQTLSVKMWTGAQ
TGIPYETFNEKRALLSEAPGVNQLARIGKKPELVYERSTVAPGSTSDYPEIGYNYTVSFDITGAKESEGTELFRSPNAVF
YLSDPIRGMMGFARDGYLNTFPYKVNPGEKATIQIEGNNRSTTLRVNGKVVDEMNTQKLYFNAGKDSMNYVRTLVFPLEK
AGNFNSKVQNLKVYNYCVSKP

Specific function: Catalyzes the cleavage of beta-N-acetylglucosaminides and beta-N-acetylgalactosaminides. Also catalyzes the hydrolysis of N-acetylchitooligomers. May be involved in chitin degradation. It is not able to cleave beta-glucosides [H]

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI189181666, Length=434, Percent_Identity=24.8847926267281, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4504373, Length=258, Percent_Identity=25.968992248062, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17569815, Length=467, Percent_Identity=21.4132762312634, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 74691; Mature: 74691

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNKFVSLQALALLVIFCLTGSLTRAAVNPKPFVVPELKQWTGKDGNFTPGKDTRIVCTS
CCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEC
QNPELLRIARMFADDYQQMFGQTLSVAQGKATSGDFVLSLSADKKLGEEGYAIKITDRVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEE
ISAPTPTGLYWSTRTLLQLAEQNQERSLPQGTIRDYPDYPLRGFMIDCGRKFIPMAYLQD
EECCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHH
LVKIMAYYKMNTLQVHLNDNGFKQYFEHNWDKTYAAFRLESETYPGLTARDGSYSKKEFI
HHHHHHHHCCEEEEEEECCCHHHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCCHHHHH
DFQKQAASNFVEIIPEIDVPAHSLALTHYKPEIGSKEYGMDHLDLFKPETYEFVDALFKE
HHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCCCCHHCCCCHHHCCCCCHHHHHHHHHHH
YLEGDNPVFVGKRVHIGTDEYSNAKKDVVEKFRAFTDHYIRFVEGFGKQAVVWGALSHAK
HHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCC
GDTPVKSENVVMNAWYNGYADPATMIKDGYQLISIPDGLVYIVPKAGYYYDYLNEPYLYK
CCCCCCCCCEEEEECCCCCCCHHHHHHCCCEEEECCCCEEEEEECCCEEEHHCCCCEEEE
EWTPAHIGKAVFDEKHPSILGGMFAIWNDHVGNGISVKDIHHRIFSPLQTLSVKMWTGAQ
CCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHEEEEECCCC
TGIPYETFNEKRALLSEAPGVNQLARIGKKPELVYERSTVAPGSTSDYPEIGYNYTVSFD
CCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEEE
ITGAKESEGTELFRSPNAVFYLSDPIRGMMGFARDGYLNTFPYKVNPGEKATIQIEGNNR
ECCCCCCCCCHHHCCCCEEEEECCCHHHHHHHCCCCCCCCCCEEECCCCEEEEEEECCCC
STTLRVNGKVVDEMNTQKLYFNAGKDSMNYVRTLVFPLEKAGNFNSKVQNLKVYNYCVSK
EEEEEECCEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEEEEECCC
P
C
>Mature Secondary Structure
MRNKFVSLQALALLVIFCLTGSLTRAAVNPKPFVVPELKQWTGKDGNFTPGKDTRIVCTS
CCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEC
QNPELLRIARMFADDYQQMFGQTLSVAQGKATSGDFVLSLSADKKLGEEGYAIKITDRVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEE
ISAPTPTGLYWSTRTLLQLAEQNQERSLPQGTIRDYPDYPLRGFMIDCGRKFIPMAYLQD
EECCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHH
LVKIMAYYKMNTLQVHLNDNGFKQYFEHNWDKTYAAFRLESETYPGLTARDGSYSKKEFI
HHHHHHHHCCEEEEEEECCCHHHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCCHHHHH
DFQKQAASNFVEIIPEIDVPAHSLALTHYKPEIGSKEYGMDHLDLFKPETYEFVDALFKE
HHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCCCCHHCCCCHHHCCCCCHHHHHHHHHHH
YLEGDNPVFVGKRVHIGTDEYSNAKKDVVEKFRAFTDHYIRFVEGFGKQAVVWGALSHAK
HHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCC
GDTPVKSENVVMNAWYNGYADPATMIKDGYQLISIPDGLVYIVPKAGYYYDYLNEPYLYK
CCCCCCCCCEEEEECCCCCCCHHHHHHCCCEEEECCCCEEEEEECCCEEEHHCCCCEEEE
EWTPAHIGKAVFDEKHPSILGGMFAIWNDHVGNGISVKDIHHRIFSPLQTLSVKMWTGAQ
CCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHEEEEECCCC
TGIPYETFNEKRALLSEAPGVNQLARIGKKPELVYERSTVAPGSTSDYPEIGYNYTVSFD
CCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEEE
ITGAKESEGTELFRSPNAVFYLSDPIRGMMGFARDGYLNTFPYKVNPGEKATIQIEGNNR
ECCCCCCCCCHHHCCCCEEEEECCCHHHHHHHCCCCCCCCCCEEECCCCEEEEEEECCCC
STTLRVNGKVVDEMNTQKLYFNAGKDSMNYVRTLVFPLEKAGNFNSKVQNLKVYNYCVSK
EEEEEECCEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEEEEECCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA