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The map label for this gene is argD [H]

Identifier: 29349166

GI number: 29349166

Start: 4878474

End: 4879595

Strand: Reverse

Name: argD [H]

Synonym: BT_3758

Alternate gene names: 29349166

Gene position: 4879595-4878474 (Counterclockwise)

Preceding gene: 29349167

Following gene: 29349165

Centisome position: 77.94

GC content: 49.64

Gene sequence:

>1122_bases
ATGAAATTATTCGACGTATATCCTTTATATGACATCAATATAGTCAAAGGACAAGGCTGTAAGGTATGGGATGAGAACGG
TACGGAATATCTGGACCTCTACGGAGGCCATGCCGTCATCTCCATCGGACACGCGCATCCCCACTATGTGGAGATGATCA
GCAATCAGGTAGCAACCCTTGGTTTCTATTCAAACTCGGTGATCAATAAGCTGCAGCAACAAGTAGCCGAACGATTGGGA
AAGATTTCCGGTTATGAAGACTACTCGCTGTTTCTGATCAACAGCGGAGCCGAAGCCAATGAAAACGCGCTGAAGCTGGC
TTCTTTCTATAACGGACGCACCAAAGTCATTTCTTTCAGCAAAGCCTTCCACGGACGTACATCCCTTGCAGTGGAGGCTA
CGAACAACCCCACCATCATTGCTCCGATCAACAACAACGGTCATGTGACCTATCTCCCTCTGAATGACATCGAAGCGATG
AAGCAGGAACTGGCGAAAGGTGACGTATGCGCTGTTATCATCGAAGGAATACAAGGAGTGGGCGGTATCAAAATACCGAC
TACCGAATTTATGCAGGAACTTCGCAAGGTTTGTACCGAAACCGGAACGATTCTGATTCTGGACGAAATCCAGAGTGGAT
ACGGCCGTAGCGGAAAATTCTTTGCCCATCAATACAACCATATCCAGCCAGACATCATCACCGTAGCCAAAGGCATCGGA
AACGGATTCCCGATGGCAGGTGTACTGATCAGCCCGATGTTCAAGCCCGTCTACGGACAACTGGGAACTACATTCGGCGG
AAATCACCTGGCCTGCTCGGCAGCTCTTGCCGTAATGGACGTCATCGAACAGGACAATCTGGTAGAAAATGCAAAAGCAG
TCGGCGACTACCTGCTGGAAGAACTCAAGAAATTCCCGCAAATCAAAGAGGTGCGCGGACGCGGACTGATGATCGGACTC
GAATTTGAAGAACCGATCAAGGAATTGCGCAGCCGCCTCATCTACGACGAACACGTATTTACGGGAGCCAGCGGGACGAA
TGTACTCCGCTTATTGCCCCCTCTCTGCCTCAGCATGGAGGAAGCGGACGAGTTCCTTGCCCGTTTCAAAAGAGTACTCT
AA

Upstream 100 bases:

>100_bases
GCCAGCGGACAAGCAGTTCATAACATGAACCTGATGTTCAACCTGGAAGAAACCGTAGGATTACGGCTGAAACCTTCCGC
TTTCTAAAAACAGAAGAATT

Downstream 100 bases:

>100_bases
CTGATATTTGATTAATAAACAGCGAACAAAAAAGCAGCCTCGAACAGAAAAACAGTTCTTATTCAGGCTGCTTTTTGTTT
TTTCGCAATTTACCGTTACC

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKLFDVYPLYDINIVKGQGCKVWDENGTEYLDLYGGHAVISIGHAHPHYVEMISNQVATLGFYSNSVINKLQQQVAERLG
KISGYEDYSLFLINSGAEANENALKLASFYNGRTKVISFSKAFHGRTSLAVEATNNPTIIAPINNNGHVTYLPLNDIEAM
KQELAKGDVCAVIIEGIQGVGGIKIPTTEFMQELRKVCTETGTILILDEIQSGYGRSGKFFAHQYNHIQPDIITVAKGIG
NGFPMAGVLISPMFKPVYGQLGTTFGGNHLACSAALAVMDVIEQDNLVENAKAVGDYLLEELKKFPQIKEVRGRGLMIGL
EFEEPIKELRSRLIYDEHVFTGASGTNVLRLLPPLCLSMEEADEFLARFKRVL

Sequences:

>Translated_373_residues
MKLFDVYPLYDINIVKGQGCKVWDENGTEYLDLYGGHAVISIGHAHPHYVEMISNQVATLGFYSNSVINKLQQQVAERLG
KISGYEDYSLFLINSGAEANENALKLASFYNGRTKVISFSKAFHGRTSLAVEATNNPTIIAPINNNGHVTYLPLNDIEAM
KQELAKGDVCAVIIEGIQGVGGIKIPTTEFMQELRKVCTETGTILILDEIQSGYGRSGKFFAHQYNHIQPDIITVAKGIG
NGFPMAGVLISPMFKPVYGQLGTTFGGNHLACSAALAVMDVIEQDNLVENAKAVGDYLLEELKKFPQIKEVRGRGLMIGL
EFEEPIKELRSRLIYDEHVFTGASGTNVLRLLPPLCLSMEEADEFLARFKRVL
>Mature_373_residues
MKLFDVYPLYDINIVKGQGCKVWDENGTEYLDLYGGHAVISIGHAHPHYVEMISNQVATLGFYSNSVINKLQQQVAERLG
KISGYEDYSLFLINSGAEANENALKLASFYNGRTKVISFSKAFHGRTSLAVEATNNPTIIAPINNNGHVTYLPLNDIEAM
KQELAKGDVCAVIIEGIQGVGGIKIPTTEFMQELRKVCTETGTILILDEIQSGYGRSGKFFAHQYNHIQPDIITVAKGIG
NGFPMAGVLISPMFKPVYGQLGTTFGGNHLACSAALAVMDVIEQDNLVENAKAVGDYLLEELKKFPQIKEVRGRGLMIGL
EFEEPIKELRSRLIYDEHVFTGASGTNVLRLLPPLCLSMEEADEFLARFKRVL

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=379, Percent_Identity=30.6068601583113, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI13994255, Length=416, Percent_Identity=30.2884615384615, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI37574042, Length=406, Percent_Identity=31.0344827586207, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=29.9760191846523, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI226442705, Length=408, Percent_Identity=29.9019607843137, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI284507298, Length=296, Percent_Identity=31.7567567567568, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI226442709, Length=376, Percent_Identity=30.3191489361702, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI188536080, Length=428, Percent_Identity=25.2336448598131, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI38679950, Length=428, Percent_Identity=25.2336448598131, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI38679946, Length=428, Percent_Identity=25.2336448598131, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI1789759, Length=389, Percent_Identity=34.4473007712082, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1788044, Length=375, Percent_Identity=34.6666666666667, Blast_Score=208, Evalue=4e-55,
Organism=Escherichia coli, GI145693181, Length=373, Percent_Identity=34.0482573726542, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1789016, Length=377, Percent_Identity=37.1352785145889, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1787560, Length=393, Percent_Identity=32.0610687022901, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1786349, Length=314, Percent_Identity=27.3885350318471, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1786991, Length=407, Percent_Identity=23.8329238329238, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=374, Percent_Identity=29.9465240641711, Blast_Score=204, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI32564660, Length=407, Percent_Identity=30.958230958231, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71992977, Length=410, Percent_Identity=29.0243902439024, Blast_Score=151, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI25144274, Length=250, Percent_Identity=31.2, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17541228, Length=420, Percent_Identity=23.5714285714286, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=138, Percent_Identity=29.7101449275362, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=387, Percent_Identity=35.6589147286822, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6323470, Length=382, Percent_Identity=30.8900523560209, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321456, Length=435, Percent_Identity=27.5862068965517, Blast_Score=115, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6324386, Length=372, Percent_Identity=27.1505376344086, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21356575, Length=410, Percent_Identity=33.4146341463415, Blast_Score=194, Evalue=9e-50,
Organism=Drosophila melanogaster, GI21357415, Length=389, Percent_Identity=28.5347043701799, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI28574759, Length=400, Percent_Identity=31.75, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI161085790, Length=401, Percent_Identity=31.9201995012469, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281366494, Length=424, Percent_Identity=23.8207547169811, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24667139, Length=424, Percent_Identity=23.8207547169811, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24667143, Length=424, Percent_Identity=23.8207547169811, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41096; Mature: 41096

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFDVYPLYDINIVKGQGCKVWDENGTEYLDLYGGHAVISIGHAHPHYVEMISNQVATL
CCEEEECCCEEEEEEECCCCEEECCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHEE
GFYSNSVINKLQQQVAERLGKISGYEDYSLFLINSGAEANENALKLASFYNGRTKVISFS
EEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEHHHHHCCCEEEEEEH
KAFHGRTSLAVEATNNPTIIAPINNNGHVTYLPLNDIEAMKQELAKGDVCAVIIEGIQGV
HHHCCCCEEEEEECCCCEEEEEECCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHCCC
GGIKIPTTEFMQELRKVCTETGTILILDEIQSGYGRSGKFFAHQYNHIQPDIITVAKGIG
CCCCCCHHHHHHHHHHHHHCCCCEEEEECHHCCCCCCCCEEEHHCCCCCCHHHHHHHHCC
NGFPMAGVLISPMFKPVYGQLGTTFGGNHLACSAALAVMDVIEQDNLVENAKAVGDYLLE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ELKKFPQIKEVRGRGLMIGLEFEEPIKELRSRLIYDEHVFTGASGTNVLRLLPPLCLSME
HHHHCCCHHHHCCCEEEEEECCHHHHHHHHHHHCHHHHEECCCCCCCHHHHHHHHHCCHH
EADEFLARFKRVL
HHHHHHHHHHHCC
>Mature Secondary Structure
MKLFDVYPLYDINIVKGQGCKVWDENGTEYLDLYGGHAVISIGHAHPHYVEMISNQVATL
CCEEEECCCEEEEEEECCCCEEECCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHEE
GFYSNSVINKLQQQVAERLGKISGYEDYSLFLINSGAEANENALKLASFYNGRTKVISFS
EEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEHHHHHCCCEEEEEEH
KAFHGRTSLAVEATNNPTIIAPINNNGHVTYLPLNDIEAMKQELAKGDVCAVIIEGIQGV
HHHCCCCEEEEEECCCCEEEEEECCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHCCC
GGIKIPTTEFMQELRKVCTETGTILILDEIQSGYGRSGKFFAHQYNHIQPDIITVAKGIG
CCCCCCHHHHHHHHHHHHHCCCCEEEEECHHCCCCCCCCEEEHHCCCCCCHHHHHHHHCC
NGFPMAGVLISPMFKPVYGQLGTTFGGNHLACSAALAVMDVIEQDNLVENAKAVGDYLLE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ELKKFPQIKEVRGRGLMIGLEFEEPIKELRSRLIYDEHVFTGASGTNVLRLLPPLCLSME
HHHHCCCHHHHCCCEEEEEECCHHHHHHHHHHHCHHHHEECCCCCCCHHHHHHHHHCCHH
EADEFLARFKRVL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025667; 9384377 [H]