Click here to switch to the map view.

The map label for this gene is citT [C]

Identifier: 29349147

GI number: 29349147

Start: 4852219

End: 4853733

Strand: Reverse

Name: citT [C]

Synonym: BT_3739

Alternate gene names: 29349147

Gene position: 4853733-4852219 (Counterclockwise)

Preceding gene: 29349152

Following gene: 29349145

Centisome position: 77.53

GC content: 43.17

Gene sequence:

>1515_bases
ATGTACAAGATTTTTCACGGCTTCCACCTAGTAGAAGCTTATCAGGACTTAAAGAAAGCTAAACGGTTAGCAAAGAATCA
GACAGTGGCCCGATGTATAAAGTTAACCATAGCTATTACCCTCTCTCTTATTTTATGGTTCCTTCCCATTGATACTTTTG
GAATAGAAGGGTTGACCGTTATAGAACAAAGACTTATTTCCATTTTCATTTTCGCCACACTCATGTGGGTGTTCGAAGCT
GTTCCGGCATGGACCACTTCCGTTCTTATTGTTGTACTATTATTACTTACCGTTTCCGACAGTAGTTTATGGTTCTTAAC
CCAAAATACTCCTGCGGAGGAATTAGGACAGACAGTCAAATATAAGTCTATCCTGCATTGCTTTGCCGATCCTATCATCA
TGCTGTTTATAGGTGGATTTATTCTTGCCATCGCAGCAACCAAAAGTGGACTGGATGTATTGTTGGCACGAGTTATGCTG
AGACCTTTCGGAACACAATCACGATATGTGCTATTGGGATTCATCCTCGTTACAGCTGTCTTTTCCATGTTTCTTAGCAA
TACGGCTACGGCGGCCATGATGCTTACCTTCCTTACTCCCGTATTAAAAGCACTCCCGGCAGATGGAAAAGGGAAAATCG
GATTGGCTATGGCCATTCCCGTTGCTGCCAATGTAGGTGGTATGGGAACTCCTATCGGTACACCACCTAACGCCATTGCT
TTAAAGTATTTGAATGATCCGGAAGGATTAAATCTGAATATCGGTTTTGGAGAATGGATGAGCTTTATGTTGCCTTACAC
TATTATTGTACTGTTTATAGCCTGGTTTATCCTCTTACGACTGTTTCCATTCAAACAAAAGAGCATCGAACTGCAAATTG
AAGGTGAAGCAAAGAAAGACTGGCGCTCCATTGTGGTTTATATCACCTTTGCTATAACGGTTCTATTGTGGATGTTCGAC
AAATTTACAGGAGTAAACTCCAATGTAGTGGCAATGATTCCGGTAGCTGTTTTTTGTATAACAGGCGTTATTACCAAACG
TGACCTGGAAGAGATCAGCTGGAGTGTACTCTGGATGGTAGCCGGCGGCTTCGCATTGGGCGTAGCCTTGCAAGAGACCG
GACTGGCAAAGCATATGATCGAAGCCATCCCATTCAGCACATGGCCCCCTGTACTGATGATTGTCGGTTCCGGACTGATT
TGCTATGCTATGGCCAACTTTATTTCACACACAGCCACCGCAGCATTACTCGTCCCTATTCTCGCCATTGCCGGAATCAG
CATGCGTGAAAACCTGTCATCGTTGGGAGGTGTAGAGACTTTATTAATTGGAGTCGCCATCGGATCATCGCTGGCAATGA
TATTACCAATTAGTACACCACCTAATGCCCTGGCACATGCCACAGGAATGATTCAGCAAAAAGATATGGAAAAGGTAGGT
ATCATTATGGGAATTATAGGACTTATCTTGGGATATACAATGCTGATCATACTCGGCTCCAACAAGTTATTATAA

Upstream 100 bases:

>100_bases
AAATATGTTAAATAAAAGAAATCTTTAACGTCAGACTAACTAAATACAAAATAAAAAGTTATTTTGCAAACGTTTTTTAA
TTTTATCTCATTCTAATATT

Downstream 100 bases:

>100_bases
ATAATCTATTAAAAAAAGAAGATGTCAAAAGCAGGATGATACATTTATCTTGCTTTTGACATCTTCTTCTTTTTCGAATT
TAGCGTCCTATAATCCTCTC

Product: Na+/dicarboxylate or sulfate symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MYKIFHGFHLVEAYQDLKKAKRLAKNQTVARCIKLTIAITLSLILWFLPIDTFGIEGLTVIEQRLISIFIFATLMWVFEA
VPAWTTSVLIVVLLLLTVSDSSLWFLTQNTPAEELGQTVKYKSILHCFADPIIMLFIGGFILAIAATKSGLDVLLARVML
RPFGTQSRYVLLGFILVTAVFSMFLSNTATAAMMLTFLTPVLKALPADGKGKIGLAMAIPVAANVGGMGTPIGTPPNAIA
LKYLNDPEGLNLNIGFGEWMSFMLPYTIIVLFIAWFILLRLFPFKQKSIELQIEGEAKKDWRSIVVYITFAITVLLWMFD
KFTGVNSNVVAMIPVAVFCITGVITKRDLEEISWSVLWMVAGGFALGVALQETGLAKHMIEAIPFSTWPPVLMIVGSGLI
CYAMANFISHTATAALLVPILAIAGISMRENLSSLGGVETLLIGVAIGSSLAMILPISTPPNALAHATGMIQQKDMEKVG
IIMGIIGLILGYTMLIILGSNKLL

Sequences:

>Translated_504_residues
MYKIFHGFHLVEAYQDLKKAKRLAKNQTVARCIKLTIAITLSLILWFLPIDTFGIEGLTVIEQRLISIFIFATLMWVFEA
VPAWTTSVLIVVLLLLTVSDSSLWFLTQNTPAEELGQTVKYKSILHCFADPIIMLFIGGFILAIAATKSGLDVLLARVML
RPFGTQSRYVLLGFILVTAVFSMFLSNTATAAMMLTFLTPVLKALPADGKGKIGLAMAIPVAANVGGMGTPIGTPPNAIA
LKYLNDPEGLNLNIGFGEWMSFMLPYTIIVLFIAWFILLRLFPFKQKSIELQIEGEAKKDWRSIVVYITFAITVLLWMFD
KFTGVNSNVVAMIPVAVFCITGVITKRDLEEISWSVLWMVAGGFALGVALQETGLAKHMIEAIPFSTWPPVLMIVGSGLI
CYAMANFISHTATAALLVPILAIAGISMRENLSSLGGVETLLIGVAIGSSLAMILPISTPPNALAHATGMIQQKDMEKVG
IIMGIIGLILGYTMLIILGSNKLL
>Mature_504_residues
MYKIFHGFHLVEAYQDLKKAKRLAKNQTVARCIKLTIAITLSLILWFLPIDTFGIEGLTVIEQRLISIFIFATLMWVFEA
VPAWTTSVLIVVLLLLTVSDSSLWFLTQNTPAEELGQTVKYKSILHCFADPIIMLFIGGFILAIAATKSGLDVLLARVML
RPFGTQSRYVLLGFILVTAVFSMFLSNTATAAMMLTFLTPVLKALPADGKGKIGLAMAIPVAANVGGMGTPIGTPPNAIA
LKYLNDPEGLNLNIGFGEWMSFMLPYTIIVLFIAWFILLRLFPFKQKSIELQIEGEAKKDWRSIVVYITFAITVLLWMFD
KFTGVNSNVVAMIPVAVFCITGVITKRDLEEISWSVLWMVAGGFALGVALQETGLAKHMIEAIPFSTWPPVLMIVGSGLI
CYAMANFISHTATAALLVPILAIAGISMRENLSSLGGVETLLIGVAIGSSLAMILPISTPPNALAHATGMIQQKDMEKVG
IIMGIIGLILGYTMLIILGSNKLL

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=529, Percent_Identity=24.7637051039698, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI301069349, Length=451, Percent_Identity=24.8337028824834, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI58761541, Length=475, Percent_Identity=24.6315789473684, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI31377715, Length=548, Percent_Identity=23.5401459854015, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI19923838, Length=330, Percent_Identity=26.0606060606061, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI301069353, Length=351, Percent_Identity=25.3561253561254, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI31795546, Length=334, Percent_Identity=25.1497005988024, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI301069346, Length=146, Percent_Identity=31.5068493150685, Blast_Score=80, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71988385, Length=479, Percent_Identity=29.6450939457203, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32565804, Length=476, Percent_Identity=29.4117647058824, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71989118, Length=497, Percent_Identity=23.5412474849095, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32564681, Length=520, Percent_Identity=22.1153846153846, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324340, Length=470, Percent_Identity=28.5106382978723, Blast_Score=153, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6322263, Length=449, Percent_Identity=26.5033407572383, Blast_Score=133, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6319885, Length=450, Percent_Identity=27.3333333333333, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI281362116, Length=549, Percent_Identity=24.2258652094718, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281362114, Length=548, Percent_Identity=24.4525547445255, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281362112, Length=548, Percent_Identity=24.4525547445255, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 54866; Mature: 54866

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKIFHGFHLVEAYQDLKKAKRLAKNQTVARCIKLTIAITLSLILWFLPIDTFGIEGLTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IEQRLISIFIFATLMWVFEAVPAWTTSVLIVVLLLLTVSDSSLWFLTQNTPAEELGQTVK
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
YKSILHCFADPIIMLFIGGFILAIAATKSGLDVLLARVMLRPFGTQSRYVLLGFILVTAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
FSMFLSNTATAAMMLTFLTPVLKALPADGKGKIGLAMAIPVAANVGGMGTPIGTPPNAIA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCEE
LKYLNDPEGLNLNIGFGEWMSFMLPYTIIVLFIAWFILLRLFPFKQKSIELQIEGEAKKD
EEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHH
WRSIVVYITFAITVLLWMFDKFTGVNSNVVAMIPVAVFCITGVITKRDLEEISWSVLWMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGGFALGVALQETGLAKHMIEAIPFSTWPPVLMIVGSGLICYAMANFISHTATAALLVPI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LAIAGISMRENLSSLGGVETLLIGVAIGSSLAMILPISTPPNALAHATGMIQQKDMEKVG
HHHCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
IIMGIIGLILGYTMLIILGSNKLL
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYKIFHGFHLVEAYQDLKKAKRLAKNQTVARCIKLTIAITLSLILWFLPIDTFGIEGLTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IEQRLISIFIFATLMWVFEAVPAWTTSVLIVVLLLLTVSDSSLWFLTQNTPAEELGQTVK
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
YKSILHCFADPIIMLFIGGFILAIAATKSGLDVLLARVMLRPFGTQSRYVLLGFILVTAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
FSMFLSNTATAAMMLTFLTPVLKALPADGKGKIGLAMAIPVAANVGGMGTPIGTPPNAIA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCEE
LKYLNDPEGLNLNIGFGEWMSFMLPYTIIVLFIAWFILLRLFPFKQKSIELQIEGEAKKD
EEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHH
WRSIVVYITFAITVLLWMFDKFTGVNSNVVAMIPVAVFCITGVITKRDLEEISWSVLWMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGGFALGVALQETGLAKHMIEAIPFSTWPPVLMIVGSGLICYAMANFISHTATAALLVPI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LAIAGISMRENLSSLGGVETLLIGVAIGSSLAMILPISTPPNALAHATGMIQQKDMEKVG
HHHCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
IIMGIIGLILGYTMLIILGSNKLL
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]