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The map label for this gene is ribD [H]

Identifier: 29349136

GI number: 29349136

Start: 4838863

End: 4839882

Strand: Reverse

Name: ribD [H]

Synonym: BT_3728

Alternate gene names: 29349136

Gene position: 4839882-4838863 (Counterclockwise)

Preceding gene: 29349143

Following gene: 29349135

Centisome position: 77.31

GC content: 47.25

Gene sequence:

>1020_bases
ATGAGACGTTGCATTGAACTGGCAAAAAACGGACTGTGCAATGTCGCTCCAAACCCGATGGTAGGGGCTGTTATCGTATG
TGACGGACTTATTATCGGCGAAGGATATCACATCCGCTGCGGAGAGGCGCATGCCGAAGTAAACGCGATTCGTTCCGTCA
AAGACAAGTCTTTATTGAGCCGTTCCACCATTTATGTCAGCCTGGAACCTTGCTCACACTACGGAAAGACGCCTCCTTGT
GCCGACTTGATTATCGAGAAGCAGATTCCCCGTATTGTAATTGGCTGTCAAGACCCGTTCTCACAGGTCGCCGGACGAGG
AATTCAGAAGTTGCGGGACGCCGGAAGAGAAGTGACAGTAGGCGTACTGGAGAAAGAATGCAGGTATCTGATCCGGCGCT
TCATTACTTTCAATACGCTGCACCGCCCCTTTATCACACTAAAATGGGCAGAATCGGCTGATCATTTCATTGATGTAGAA
CGAACAGACGGCAATCCCGTAGTACTGTCCTCCCCTCTTACTTCCATGCTTGTACATAAAAAGAGAGCGGAAACTGATGC
AATCATGGTAGGCAGGCGGACAGCATTGTTGGACAATCCGTCGCTGACAGTCCGCAACTGGTACGGCCGGAATCCGGTAC
GCATCGTTTTGGACCGTGCATTGTCTCTTCCCCACAGCCTGCGTCTGTTTGACGGAGAAGTACCCACCATCGTATTTACA
GCAGAAAAACATCCGGACAAGAAGAACGTCACATACCGCACGATTGAATTCACACAGGATATTCTGCCACAGATCATGAA
AGTGCTATATCAACAAAAAATACAGTCCTTACTGGTAGAGGGAGGAAGTCAGCTGCTCCAATCATTTATTGATGCCGAAC
TATGGGATGAAGTATATATTGAGAAATGTCCGTGCAAGCTGAATTCCGGTGTTAAAGCACCTGAAATAAGCGATAATTTT
AGTTATTCGACTGAAAAACACTTCGACAGACAGATTTGGCATTATGTTTTCGAGAAATAG

Upstream 100 bases:

>100_bases
TGACGAATGTAAGCAGTGATGCGGTTCATATTTTACGATTTCGGAGTGCAAAAGTAAGAATAATATAGCGAAGAGCACCA
AAATGGAAGAAGAAAAATAC

Downstream 100 bases:

>100_bases
CTAAAATAGTTCTATTCAAGGGGTTCTACGTCGATAAAAACAGCGTTATTATCTATAATTTTATATAAAACTTCCCCTTA
ATGTTCTATATCGGAAAAAA

Product: riboflavin biosynthesis protein ribD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MRRCIELAKNGLCNVAPNPMVGAVIVCDGLIIGEGYHIRCGEAHAEVNAIRSVKDKSLLSRSTIYVSLEPCSHYGKTPPC
ADLIIEKQIPRIVIGCQDPFSQVAGRGIQKLRDAGREVTVGVLEKECRYLIRRFITFNTLHRPFITLKWAESADHFIDVE
RTDGNPVVLSSPLTSMLVHKKRAETDAIMVGRRTALLDNPSLTVRNWYGRNPVRIVLDRALSLPHSLRLFDGEVPTIVFT
AEKHPDKKNVTYRTIEFTQDILPQIMKVLYQQKIQSLLVEGGSQLLQSFIDAELWDEVYIEKCPCKLNSGVKAPEISDNF
SYSTEKHFDRQIWHYVFEK

Sequences:

>Translated_339_residues
MRRCIELAKNGLCNVAPNPMVGAVIVCDGLIIGEGYHIRCGEAHAEVNAIRSVKDKSLLSRSTIYVSLEPCSHYGKTPPC
ADLIIEKQIPRIVIGCQDPFSQVAGRGIQKLRDAGREVTVGVLEKECRYLIRRFITFNTLHRPFITLKWAESADHFIDVE
RTDGNPVVLSSPLTSMLVHKKRAETDAIMVGRRTALLDNPSLTVRNWYGRNPVRIVLDRALSLPHSLRLFDGEVPTIVFT
AEKHPDKKNVTYRTIEFTQDILPQIMKVLYQQKIQSLLVEGGSQLLQSFIDAELWDEVYIEKCPCKLNSGVKAPEISDNF
SYSTEKHFDRQIWHYVFEK
>Mature_339_residues
MRRCIELAKNGLCNVAPNPMVGAVIVCDGLIIGEGYHIRCGEAHAEVNAIRSVKDKSLLSRSTIYVSLEPCSHYGKTPPC
ADLIIEKQIPRIVIGCQDPFSQVAGRGIQKLRDAGREVTVGVLEKECRYLIRRFITFNTLHRPFITLKWAESADHFIDVE
RTDGNPVVLSSPLTSMLVHKKRAETDAIMVGRRTALLDNPSLTVRNWYGRNPVRIVLDRALSLPHSLRLFDGEVPTIVFT
AEKHPDKKNVTYRTIEFTQDILPQIMKVLYQQKIQSLLVEGGSQLLQSFIDAELWDEVYIEKCPCKLNSGVKAPEISDNF
SYSTEKHFDRQIWHYVFEK

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=334, Percent_Identity=35.6287425149701, Blast_Score=177, Evalue=7e-46,
Organism=Escherichia coli, GI145693172, Length=126, Percent_Identity=35.7142857142857, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 38462; Mature: 38462

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRCIELAKNGLCNVAPNPMVGAVIVCDGLIIGEGYHIRCGEAHAEVNAIRSVKDKSLLS
CHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCEEEECCCHHHHHHHHHHHHHHHHHC
RSTIYVSLEPCSHYGKTPPCADLIIEKQIPRIVIGCQDPFSQVAGRGIQKLRDAGREVTV
CCEEEEEECCHHCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEH
GVLEKECRYLIRRFITFNTLHRPFITLKWAESADHFIDVERTDGNPVVLSSPLTSMLVHK
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCEEEECCCHHHHHHHH
KRAETDAIMVGRRTALLDNPSLTVRNWYGRNPVRIVLDRALSLPHSLRLFDGEVPTIVFT
HHCCCCCEEECCCEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCCEEEEE
AEKHPDKKNVTYRTIEFTQDILPQIMKVLYQQKIQSLLVEGGSQLLQSFIDAELWDEVYI
ECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
EKCPCKLNSGVKAPEISDNFSYSTEKHFDRQIWHYVFEK
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRCIELAKNGLCNVAPNPMVGAVIVCDGLIIGEGYHIRCGEAHAEVNAIRSVKDKSLLS
CHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCEEEECCCHHHHHHHHHHHHHHHHHC
RSTIYVSLEPCSHYGKTPPCADLIIEKQIPRIVIGCQDPFSQVAGRGIQKLRDAGREVTV
CCEEEEEECCHHCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEH
GVLEKECRYLIRRFITFNTLHRPFITLKWAESADHFIDVERTDGNPVVLSSPLTSMLVHK
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCEEEECCCHHHHHHHH
KRAETDAIMVGRRTALLDNPSLTVRNWYGRNPVRIVLDRALSLPHSLRLFDGEVPTIVFT
HHCCCCCEEECCCEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCCEEEEE
AEKHPDKKNVTYRTIEFTQDILPQIMKVLYQQKIQSLLVEGGSQLLQSFIDAELWDEVYI
ECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
EKCPCKLNSGVKAPEISDNFSYSTEKHFDRQIWHYVFEK
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]